메뉴 건너뛰기




Volumn 21, Issue 1, 2013, Pages 64-72

Demonstration of CDX2 is highly antibody dependant

Author keywords

antibody clone; CDX2; external quality control; laboratory proficiency; protocol optimization

Indexed keywords

ANTIBODY; CDX2 88 ANTIBODY; DAK CDX2 ANTIBODY; EPR2764Y ANTIBODY; TRANSCRIPTION FACTOR CDX2; UNCLASSIFIED DRUG;

EID: 84871982705     PISSN: 15412016     EISSN: 15334058     Source Type: Journal    
DOI: 10.1097/PAI.0b013e318257f8aa     Document Type: Article
Times cited : (24)

References (51)
  • 1
    • 0030032310 scopus 로고    scopus 로고
    • An intestine-specific homeobox gene regulates proliferation and differentiation
    • Suh E, Traber PG. An intestine-specific homeobox gene regulates proliferation and differentiation. Mol Cell Biol. 1996;16:619-625. (Pubitemid 26029101)
    • (1996) Molecular and Cellular Biology , vol.16 , Issue.2 , pp. 619-625
    • Suh, E.1    Traber, P.G.2
  • 2
    • 0031446727 scopus 로고    scopus 로고
    • Cloning and chromosome assignment of the human CDX2 gene
    • DOI 10.1017/S0003480097006465
    • Drummond F, Putt W, Fox M, et al. Cloning and chromosome assignment of the human CDX2 gene. Ann Hum Genet. 1997;5:393-400. (Pubitemid 28040820)
    • (1997) Annals of Human Genetics , vol.61 , Issue.5 , pp. 393-400
    • Drummond, F.1    Putt, W.2    Fox, M.3    Edwards, Y.H.4
  • 3
    • 36248939194 scopus 로고    scopus 로고
    • CDX2 expression is progressively decreased in human gastric intestinal metaplasia, dysplasia and cancer
    • DOI 10.1038/modpathol.3800968, PII 3800968
    • Liu Q, The M, Ito K, et al. CDX2 expression is progressively decreased in human gastric intestinal metaplasia, dysplasia and cancer. Mod Pathol. 2007;20:1286-1297. (Pubitemid 350126854)
    • (2007) Modern Pathology , vol.20 , Issue.12 , pp. 1286-1297
    • Liu, Q.1    Teh, M.2    Ito, K.3    Shah, N.4    Ito, Y.5    Yeoh, K.G.6
  • 4
    • 0141742109 scopus 로고    scopus 로고
    • Cdx2 protein expression in normal and malignant human tissues: An immunohistochemical survey using tissue microarrays
    • DOI 10.1097/01.MP.0000086073.92773.55
    • Moskaluk CA, Zhang H, Powell SM, et al. CDX2 protein expression in normal and malignant human tissues: an immunohis-tochemical survey using tissue microarrays. Mod Pathol. 2003; 16:913-919. (Pubitemid 37152021)
    • (2003) Modern Pathology , vol.16 , Issue.9 , pp. 913-919
    • Moskaluk, C.A.1    Zhang, H.2    Powell, S.M.3    Cerilli, L.A.4    Hampton, G.M.5    Frierson Jr., H.F.6
  • 6
    • 0142200932 scopus 로고    scopus 로고
    • Cdx2 as a Marker of Epithelial Intestinal Differentiation in the Esophagus
    • DOI 10.1097/00000478-200311000-00006
    • Phillips RW, Frierson HF Jr, Moskaluk CA. Cdx2 as a marker of epithelial intestinal differentiation in the esophagus. Am J Surg Pathol. 2003;11:1442-1447. (Pubitemid 37315196)
    • (2003) American Journal of Surgical Pathology , vol.27 , Issue.11 , pp. 1442-1447
    • Phillips, R.W.1    Frierson Jr., H.F.2    Moskaluk, C.A.3
  • 9
    • 74249088974 scopus 로고    scopus 로고
    • Immunophenotype and molecular characterisation of adenocarcinoma of the small intestine
    • Overman MJ, Pozadzides J, Kopetz S, et al. Immunophenotype and molecular characterisation of adenocarcinoma of the small intestine. Br J Cancer. 2010;102:144-150.
    • (2010) Br J Cancer. , vol.102 , pp. 144-150
    • Overman, M.J.1    Pozadzides, J.2    Kopetz, S.3
  • 10
    • 0037371192 scopus 로고    scopus 로고
    • CDX2, a highly sensitive and specific marker of adenocarcinomas of intestinal origin
    • Werling RW, Yaziji H, Bacchi CE, et al. CDX2, a highly sensitive and specific marker of adenocarcinomas of intestinal origin. Am J Surg Pathol. 2003;27:303-310.
    • (2003) Am J Surg Pathol. , vol.27 , pp. 303-310
    • Werling, R.W.1    Yaziji, H.2    Bacchi, C.E.3
  • 12
    • 84863989940 scopus 로고    scopus 로고
    • Expression of homeo-domain protein CDX2 in colorectal adenoma and adenocarcinoma
    • Bakaris S, Cetinkaya A, Ezberci F, et al. Expression of homeo-domain protein CDX2 in colorectal adenoma and adenocarcinoma. Histol Histopathol. 2008;23:1043-1047.
    • (2008) Histol Histopathol. , vol.23 , pp. 1043-1047
    • Bakaris, S.1    Cetinkaya, A.2    Ezberci, F.3
  • 13
    • 24144498763 scopus 로고    scopus 로고
    • CDX2 is a useful marker of intestinal-type differentiation
    • De Lott LB, Morrison C, Suster S, et al. CDX2 is a useful marker of intestinal-type differentiation. Arch Pathol Lab Med. 2005;129: 1100-1105.
    • (2005) Arch Pathol Lab Med. , vol.129 , pp. 1100-1105
    • De Lott, L.B.1    Morrison, C.2    Suster, S.3
  • 16
    • 68049113677 scopus 로고    scopus 로고
    • Relationship of CDX2 loss with molecular features and prognosis in colorectal cancer
    • Baba Y, Nosho K, Shima K, et al. Relationship of CDX2 loss with molecular features and prognosis in colorectal cancer. Clin Cancer Res. 2009;15:4665-4673.
    • (2009) Clin Cancer Res. , vol.15 , pp. 4665-4673
    • Baba, Y.1    Nosho, K.2    Shima, K.3
  • 18
    • 59049083733 scopus 로고    scopus 로고
    • Differentiating the indiffer-entiated: Immunohistochemical profile of medullary carcinoma of the colon with an emphasis on intestinal differentiation
    • Winn B, Tavares R, Fanion J, et al. Differentiating the indiffer-entiated: immunohistochemical profile of medullary carcinoma of the colon with an emphasis on intestinal differentiation. Hum Pathol. 2009;40:398-404.
    • (2009) Hum Pathol. , vol.40 , pp. 398-404
    • Winn, B.1    Tavares, R.2    Fanion, J.3
  • 19
    • 0037221727 scopus 로고    scopus 로고
    • Expression of intestine-specific transcription factors, CDX1 and CDX2, in intestinal metaplasia and gastric carcinomas
    • DOI 10.1002/path.1246
    • Almeida R, Silva E, Santos-Silva F, et al. Expression of intestine-specific transcription factors, CDX1 and CDX2, in intestinal metaplasia and gastric carcinomas. J Pathol. 2003;199:36-40. (Pubitemid 36054727)
    • (2003) Journal of Pathology , vol.199 , Issue.1 , pp. 36-40
    • Almeida, R.1    Silva, E.2    Santos-Silva, F.3    Silberg, D.G.4    Wang, J.5    De Bolos, C.6    David, L.7
  • 20
    • 14844320543 scopus 로고    scopus 로고
    • Utility of immunohistochemistry in distinguishing primary adenocarcinomas from metastatic breast carcinomas in the gastrointestinal tract
    • O'Connell FP, Wang HH, Odze RD. Utility of immunohistochem-istry in distinguishing primary adenocarcinomas from metastatic breast carcinomas in the gastrointestinal tract. Arch Pathol Lab Med. 2005;129:338-347. (Pubitemid 40343988)
    • (2005) Archives of Pathology and Laboratory Medicine , vol.129 , Issue.3 , pp. 338-347
    • O'Connell, F.P.1    Wang, H.H.2    Odze, R.D.3
  • 21
    • 12344329808 scopus 로고    scopus 로고
    • Use of novel immunohistochemical markers expressed in colonic adenocarcinoma to distinguish primary ovarian tumors from metastatic colorectal carcinoma
    • DOI 10.1038/modpathol.3800260
    • Logani S, Oliva E, Arnell PM, et al. Use of novel immunohisto-chemical markers expressed in colonic adenocarcinoma to distinguish primary ovarian tumors from metastatic colorectal carcinoma. Mod Pathol. 2005;18:19-25. (Pubitemid 40128090)
    • (2005) Modern Pathology , vol.18 , Issue.1 , pp. 19-25
    • Logani, S.1    Oliva, E.2    Arnell, P.M.3    Amin, M.B.4    Young, R.H.5
  • 22
    • 33750304107 scopus 로고    scopus 로고
    • Immunohistochemical expression of CDX2 in primary ovarian mucinous tumors and metastatic mucinous carcinomas involving the ovary: Comparison with CK20 and correlation with coordinate expression of CK7
    • DOI 10.1038/modpathol.3800698, PII 3800698
    • Vang R, Gown AM, Wu LSF, et al. Immunohistochemical expression of CDX2 in primary ovarian mucinous tumors and metastatic mucinous carcinomas involving the ovary: comparison with CK20 and correlation with coordinate expression of CK7. Mod Pathol. 2006;19:1421-1428. (Pubitemid 44624160)
    • (2006) Modern Pathology , vol.19 , Issue.11 , pp. 1421-1428
    • Vang, R.1    Gown, A.M.2    Wu, L.-S.-F.3    Barry, T.S.4    Wheeler, D.T.5    Yemelyanova, A.6    Seidman, J.D.7    Ronnett, B.M.8
  • 24
    • 79955918354 scopus 로고    scopus 로고
    • Low-grade nonintestinal sinonasal adenocarcinoma: A diagnosis of exclusion
    • Bhaijee F, Carron J, Bell D. Low-grade nonintestinal sinonasal adenocarcinoma: a diagnosis of exclusion. Ann Diagn Pathol. 2011;15:181-184.
    • (2011) Ann Diagn Pathol. , vol.15 , pp. 181-184
    • Bhaijee, F.1    Carron, J.2    Bell, D.3
  • 25
    • 30544436321 scopus 로고    scopus 로고
    • Value of CDX2, villin, and α-methylacyl coenzyme A racemase immunostains in the distinction between primary adenocarcinoma of the bladder and secondary colorectal adenocarcinoma
    • DOI 10.1038/modpathol.3800407, PII 3800407
    • Suh N, Yang XJ, Tretiakova MS, et al. Value of CDX2, villin, and alpha-methylacyl coenzyme A racemase immunostains in the distinction between primary adenocarcinoma of the bladder and secondary colorectal adenocarcinoma. Mod Pathol. 2005;18:1217-1222. (Pubitemid 43079921)
    • (2005) Modern Pathology , vol.18 , Issue.9 , pp. 1217-1222
    • Suh, N.1    Yang, X.J.2    Tretiakova, M.S.3    Humphrey, P.A.4    Wang, H.L.5
  • 26
    • 79957992674 scopus 로고    scopus 로고
    • Immunohistochemical analysis in a morphologic spectrum of urachal epithelial neoplasms: Diagnostic implications and pitfalls
    • Paner GP, McKenney JK, Barkan GA, et al. Immunohistochemical analysis in a morphologic spectrum of urachal epithelial neoplasms: diagnostic implications and pitfalls. Am J Surg Pathol. 2011;35:787-798.
    • (2011) Am J Surg Pathol. , vol.35 , pp. 787-798
    • Paner, G.P.1    McKenney, J.K.2    Barkan, G.A.3
  • 27
    • 4344644561 scopus 로고    scopus 로고
    • CDX-2 homeobox gene product expression in neuroendocrine tumors
    • Barbareschi M, Roldo C, Zamboni G, et al. CDX-2 homeobox gene product expression in neuroendocrine tumors. Am J Surg Pathol. 2004;28:1169-1179.
    • (2004) Am J Surg Pathol. , vol.28 , pp. 1169-1179
    • Barbareschi, M.1    Roldo, C.2    Zamboni, G.3
  • 29
    • 33749458480 scopus 로고    scopus 로고
    • Expression of the intestinal transcription factor CDX2 in carcinoid tumors is a marker of midgut origin
    • Jaffee IM, Rahmani M, Singhal MG, et al. Expression of the intestinal transcription factor CDX2 in carcinoid tumors is a marker of midgut origin. Arch Pathol Lab Med. 2006;130:1522-1526. (Pubitemid 44520720)
    • (2006) Archives of Pathology and Laboratory Medicine , vol.130 , Issue.10 , pp. 1522-1526
    • Jaffee, I.M.1    Rahmani, M.2    Singhal, M.C.3    Younes, M.4
  • 30
    • 14644411795 scopus 로고    scopus 로고
    • Usefulness of CDX2 and TTF-1 in differentiating gastrointestinal from pulmonary carcinoids
    • DOI 10.1309/UKN6-PVRK-XHG4-22DA
    • Saqi A, Alexis D, Remotti F, et al. Usefulness of CDX2 and TTF-1 in differentiating gastrointestinal from pulmonary carcinoids. Am J Surg Pathol. 2005;123:394-404. (Pubitemid 40315081)
    • (2005) American Journal of Clinical Pathology , vol.123 , Issue.3 , pp. 394-404
    • Saqi, A.1    Alexis, D.2    Remotti, F.3    Bhagat, G.4
  • 31
    • 14644440543 scopus 로고    scopus 로고
    • Immunohistochemical staining in the diagnosis of pancreatobiliary and ampulla of Vater adenocarcinoma: Application of CDX2, CK17, MUC1, and MUC2
    • DOI 10.1097/01.pas.0000149708.12335.6a
    • Chu PG, Schwarz RE, Lau SK, et al. Immunohistochemical staining in the diagnosis of pancreatobiliary and ampulla of Vater adenocarcinoma. Am J Surg Pathol. 2005;29:359-367. (Pubitemid 40321972)
    • (2005) American Journal of Surgical Pathology , vol.29 , Issue.3 , pp. 359-367
    • Chu, P.G.1    Schwarz, R.E.2    Lau, S.K.3    Yen, Y.4    Weiss, L.M.5
  • 32
    • 70349563903 scopus 로고    scopus 로고
    • CDX-2 expression is a common event in primary intestinal-type endocervical adenocarcinoma
    • Saad RS, Ismiil N, Dube V, et al. CDX-2 expression is a common event in primary intestinal-type endocervical adenocarcinoma. Am J Clin Pathol. 2009;132:531-538.
    • (2009) Am J Clin Pathol. , vol.132 , pp. 531-538
    • Saad, R.S.1    Ismiil, N.2    Dube, V.3
  • 33
    • 56149088548 scopus 로고    scopus 로고
    • Comprehensive evaluation of CDX2 in invasive cervical adenocarcinomas
    • Sullivan LM, Smolkin ME, Frierson HF, et al. Comprehensive evaluation of CDX2 in invasive cervical adenocarcinomas. Am J Surg Pathol. 2008;32:1608-1612.
    • (2008) Am J Surg Pathol. , vol.32 , pp. 1608-1612
    • Sullivan, L.M.1    Smolkin, M.E.2    Frierson, H.F.3
  • 34
    • 70349546316 scopus 로고    scopus 로고
    • CDX2 expression in yolk sac component of testicular germ cell tumors
    • Bing Z, Pasha T, Tomaszewski JE, et al. CDX2 expression in yolk sac component of testicular germ cell tumors. Int J Surg Pathol. 2009;17:373-377.
    • (2009) Int J Surg Pathol. , vol.17 , pp. 373-377
    • Bing, Z.1    Pasha, T.2    Tomaszewski, J.E.3
  • 35
    • 2642567642 scopus 로고    scopus 로고
    • CK20 expression, CDX2 expression, K-ras mutation, and goblet cell morphology in a subset of lung adenocarcinomas
    • DOI 10.1002/path.1566
    • Yatabe Y, Koga T, Mitsudomi T, et al. CK20 expression, CDX2 expression, K-ras mutation, and goblet cell morphology in a subset of lung adenocarcinomas. J Pathol. 2004;203:645-652. (Pubitemid 38714101)
    • (2004) Journal of Pathology , vol.203 , Issue.2 , pp. 645-652
    • Yatabe, Y.1    Koga, T.2    Mitsudomi, T.3    Takahashi, T.4
  • 36
    • 34247124145 scopus 로고    scopus 로고
    • Primary lung cancer presenting with gastrointestinal tract involvement: Clinicopathologic and immunohistochemical features in a series of 18 consecutive cases
    • PII 0124389420070200000004
    • Rossi G, Marchioni A, Romagnani E, et al. Primary lung cancer presenting with gastrointestinal tract involvement: clinicopathologic and immunohistochemical features in a series of 18 consecutive cases. J Thorac Oncol. 2007;2:115-120. (Pubitemid 47181338)
    • (2007) Journal of Thoracic Oncology , vol.2 , Issue.2 , pp. 115-120
    • Rossi, G.1    Marchioni, A.2    Romagnani, E.3    Bertolini, F.4    Longo, L.5    Cavazza, A.6    Barbieri, F.7
  • 37
    • 35948994055 scopus 로고    scopus 로고
    • Utility of tissue-specific transcription factors thyroid transcription factor 1 and Cdx2 in determining the primary site of metastatic adenocarcinomas to the brain
    • Strickland-Marmol LB, Khoor A, Livingston SK, et al. Utility of tissue-specific transcription factors thyroid transcription factor 1 and Cdx2 in determining the primary site of metastatic adenocarci-nomas to the brain. Arch Pathol Lab Med. 2007;131:1686-1690. (Pubitemid 350077466)
    • (2007) Archives of Pathology and Laboratory Medicine , vol.131 , Issue.11 , pp. 1686-1690
    • Strickland-Marmol, L.B.1    Khoor, A.2    Livingston, S.K.3    Rojiani, A.4
  • 38
    • 47749156446 scopus 로고    scopus 로고
    • Morules in endometrioid proliferations of the uterus and ovary consistently express the intestinal transcription factor CDX2
    • DOI 10.1111/j.1365-2559.2008.03083.x
    • Houghton O, Connolly LE, McCluggage WG. Morules in endometrioid proliferations of the uterus and ovary consistently express the intestinal transcription factor CDX2. Histopathology. 2008;53:156-165. (Pubitemid 352032773)
    • (2008) Histopathology , vol.53 , Issue.2 , pp. 156-165
    • Houghton, O.1    Connolly, L.E.2    McCluggage, W.G.3
  • 39
    • 33846452138 scopus 로고    scopus 로고
    • Urothelial-type adenocarcinoma of the prostate mimicking metastatic colorectal adenocarcinoma
    • Adley BP, Maxwell K, Dalton DP, et al. Urothelial-type adeno-carcinoma of the prostate mimicking metastatic colorectal adeno-carcinoma. Int Braz J Urol. 2006;32:681-687. (Pubitemid 46138856)
    • (2006) International Braz J Urol , vol.32 , Issue.6 , pp. 681-687
    • Adley, B.P.1    Maxwell, K.2    Dalton, D.P.3    Yang, X.J.4
  • 40
    • 46749114801 scopus 로고    scopus 로고
    • Cdx2, cytokeratin 20, thyroid transcription factor 1, and prostate-specific antigen expression in unusual subtypes of prostate cancer
    • Leite KR, Mitteldorf CA, Srougi M, et al. Cdx2, cytokeratin 20, thyroid transcription factor 1, and prostate-specific antigen expression in unusual subtypes of prostate cancer. Ann Diagn Pathol. 2008;12:260-266.
    • (2008) Ann Diagn Pathol. , vol.12 , pp. 260-266
    • Leite, K.R.1    Mitteldorf, C.A.2    Srougi, M.3
  • 41
    • 84871972350 scopus 로고    scopus 로고
    • http://www.nordiqc.org/Run-27-B8-C2/Assessment/assessment-27-CDX2.htm.
  • 42
    • 84871969192 scopus 로고    scopus 로고
    • Accessed July 25, 2011
    • Available at: http://www.webcitation.org/60RaNqrY7. Accessed July 25, 2011.
  • 43
    • 84871982471 scopus 로고    scopus 로고
    • http://www.cellmarque.com/cmc/P-antibodydetail.php?id = 2025.
  • 44
    • 84871951309 scopus 로고    scopus 로고
    • Accessed July 25, 2011
    • Available at: http://www.webcitation.org/60Rb5MnQP. Accessed July 25, 2011.
  • 45
    • 84871960347 scopus 로고    scopus 로고
    • http://www.dako.com/us/download.pdf?objectid=118787001.
  • 46
    • 84871942775 scopus 로고    scopus 로고
    • Accessed July 25, 2011
    • Available at: http://www.webcitation.org/60Ray4dwv. Accessed July 25, 2011.
  • 47
    • 84871950005 scopus 로고    scopus 로고
    • http://www.leica-microsystems.com/fileadmin/img-uploads/novoc astra-reagents/Novocastra-datasheets/cdx2.pdf.
  • 48
    • 84871943345 scopus 로고    scopus 로고
    • Accessed July 25, 2011
    • Available at: http://www.webcitation.org/60RafgPJ7. Accessed July 25, 2011.
  • 49
    • 84871940970 scopus 로고    scopus 로고
    • http://www.biogenex.com/int-doc/DS-English/932-392M-EN12492926 79.pd.
  • 50
    • 84871971508 scopus 로고    scopus 로고
    • Accessed July 25, 2011
    • Available at: http://www.webcitation.org/60Rb1yOmb. Accessed July 25, 2011.


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.