메뉴 건너뛰기




Volumn 132, Issue 4, 2009, Pages 531-538

CDX-2 expression is a common event in primary intestinal-type endocervical adenocarcinoma

Author keywords

CDX 2; Cervical adenocarcinoma; Intestinal differentiation

Indexed keywords

CYTOKERATIN 20; CYTOKERATIN 7; PROTEIN P16; TRANSCRIPTION FACTOR CDX2; CDX 2 3 PROTEIN; CDX-2-3 PROTEIN; CYCLIN DEPENDENT KINASE INHIBITOR 2A; HOMEODOMAIN PROTEIN; TRANSACTIVATOR PROTEIN;

EID: 70349563903     PISSN: 00029173     EISSN: None     Source Type: Journal    
DOI: 10.1309/AJCP7E5ASGOENPFP     Document Type: Article
Times cited : (14)

References (44)
  • 1
    • 0037905503 scopus 로고    scopus 로고
    • Diagnostic and therapeutic management of cancer of an unknown primary
    • DOI 10.1016/S0959-8049(03)00547-1
    • Pavlidis N, Briasoulis E, Hainsworth J, et al. Diagnostic and therapeutic management of cancer of unknown primary. Eur J Cancer. 2003;39:1990-2005. (Pubitemid 37297755)
    • (2003) European Journal of Cancer , vol.39 , Issue.14 , pp. 1990-2005
    • Pavlidis, N.1    Briasoulis, E.2    Hainsworth, J.3    Greco, F.A.4
  • 2
    • 0037294510 scopus 로고    scopus 로고
    • The unknown biology of the unknown primary tumour: A literature review
    • DOI 10.1093/annonc/mdg068
    • van de Wouw AJ, Jansen RI, Speel EJ, et al. The unknown biology of the unknown primary tumor: a literature review. Ann Oncol. 2003;14:191-196. (Pubitemid 36305428)
    • (2003) Annals of Oncology , vol.14 , Issue.2 , pp. 191-196
    • Van De Wouw, A.J.1    Jansen, R.L.H.2    Speel, E.J.M.3    Hillen, H.F.P.4
  • 3
    • 1942530860 scopus 로고    scopus 로고
    • Diagnostic Strategies for Unknown Primary Cancer
    • DOI 10.1002/cncr.20202
    • Varadhachary GR, Abbruzzese JL, Lenzi R. Diagnostic strategies for unknown primary cancer. Cancer. 2004;100:1776-1785. (Pubitemid 38529553)
    • (2004) Cancer , vol.100 , Issue.9 , pp. 1776-1785
    • Varadhachary, G.R.1    Abbruzzese, J.L.2    Lenzi, R.3
  • 4
    • 35348931111 scopus 로고    scopus 로고
    • Panels of immunohistochemical markers help determine primary sites of metastatic adenocarcinoma
    • Park S-Y, Kim B-H, Kim J-H, et al. Panels of immunohistochemical markers help determine primary sites of metastatic adenocarcinoma. Arch Pathol Lab Med. 2007;131:1561-1567.
    • (2007) Arch Pathol Lab Med. , vol.131 , pp. 1561-1567
    • Park, S.-Y.1    Kim, B.-H.2    Kim, J.-H.3
  • 5
    • 0029013612 scopus 로고
    • Coordinate expression of cytokeratins 7 and 20 defines unique subsets of carcinomas
    • Wang NP, Zee S, Zarbo RJ, et al. Coordinate expression of cytokeratins 7 and 20 defines unique subsets of carcinomas. Appl Immunohistochem Mol Morphol. 1995;3:99-107.
    • (1995) Appl Immunohistochem Mol Morphol. , vol.3 , pp. 99-107
    • Wang, N.P.1    Zee, S.2    Zarbo, R.J.3
  • 6
    • 0033795923 scopus 로고    scopus 로고
    • Cytokeratin 7 and Cytokeratin 20 expression in epithelial neoplasms: A survey of 435 cases
    • Chu P, Wu E, Weiss LM. Cytokeratin 7 and cytokeratin 20 expression in epithelial neoplasms: a survey of 435 cases. Mod Pathol. 2000;13:962-972. (Pubitemid 30736647)
    • (2000) Modern Pathology , vol.13 , Issue.9 , pp. 962-972
    • Chu, P.1    Wu, E.2    Weiss, L.M.3
  • 7
    • 0034801209 scopus 로고    scopus 로고
    • Identifying the primary sites of metastatic carcinoma: The increasing role of immunohistochemistry
    • DOI 10.1054/cdip.2001.0079
    • Pecciarini L, Cangi MG, Doglioni C. Identifying the primary sites of metastatic carcinoma: the increasing role of immunohistochemistry. Curr Diagn Pathol. 2001;7:168-175. (Pubitemid 32906449)
    • (2001) Current Diagnostic Pathology , vol.7 , Issue.3 , pp. 168-175
    • Pecciarini, L.1    Giulia Cangi, M.2    Doglioni, C.3
  • 8
    • 0031899634 scopus 로고    scopus 로고
    • Tracing the origin of adenocarcinomas with unknown primary using immunohistochemistry: Differential diagnosis between colonic and ovarian carcinomas as primary sites
    • DOI 10.1016/S0046-8177(98)90065-X
    • Lagendijk JH, Mullink H, Van Diest PJ, et al. Tracing the origin of adenocarcinomas with unknown primary using immunohistochemistry: differential diagnosis between colonic and ovarian carcinomas as primary sites. Hum Pathol. 1998;29:491-497. (Pubitemid 28213469)
    • (1998) Human Pathology , vol.29 , Issue.5 , pp. 491-497
    • Lagendijk, J.H.1    Mullink, H.2    Van Diest, P.J.3    Meijer, G.A.4    Meijer, C.J.L.M.5
  • 9
    • 0029161088 scopus 로고
    • Keratins 7 and 20 as diagnostic markers of carcinomas metastatic to the ovary
    • Wauters CAP, Smedts F, Gerrits LG, et al. Keratins 7 and 20 as diagnostic markers of carcinomas metastatic to the ovary. Hum Pathol. 1995;26:850-855.
    • (1995) Hum Pathol. , vol.26 , pp. 850-855
    • Wauters, C.A.P.1    Smedts, F.2    Gerrits, L.G.3
  • 10
    • 0030802982 scopus 로고    scopus 로고
    • Differences in expression of homeobox transcription factors in proximal and distal human small intestine
    • DOI 10.1053/gast.1997.v113.pm9247466
    • Walters JR, Howard A, Rumble HE, et al. Differences in expression of homeobox transcription factors in proximal and distal human small intestine. Gastroenterology. 1997;113:472-477. (Pubitemid 27351773)
    • (1997) Gastroenterology , vol.113 , Issue.2 , pp. 472-477
    • Walters, J.R.F.1    Howard, A.2    Rumble, H.E.E.3    Prathalingam, S.R.4    Shaw-Smith, C.J.5    Legon, S.6
  • 11
    • 0028243649 scopus 로고
    • Structure of the murine homeobox gene cdx-2. Expression in embryonic and adult intestinal epithelium
    • James R, Erler T, Kazenwadel J. Structure of the murine homeobox gene, cdx-2: expression in embryonic and adult intestinal epithelium. J Biol Chem. 1994;269:15229-15237. (Pubitemid 24198371)
    • (1994) Journal of Biological Chemistry , vol.269 , Issue.21 , pp. 15229-15237
    • James, R.1    Erler, T.2    Kazenwadel, J.3
  • 12
    • 0037371192 scopus 로고    scopus 로고
    • CDX2, a highly sensitive and specific marker of adenocarcinomas of intestinal origin: An immunohistochemical survey of 476 primary and metastatic carcinomas
    • DOI 10.1097/00000478-200303000-00003
    • Werling RW, Yaziji H, Bacchi CE, et al. CDX-2, a highly sensitive and specific marker of adenocarcinomas of intestinal origin: an immunohistochemical survey of 476 primary and metastatic carcinomas. Am J Surg Pathol. 2003;27:303-310. (Pubitemid 36245795)
    • (2003) American Journal of Surgical Pathology , vol.27 , Issue.3 , pp. 303-310
    • Werling, R.W.1    Yaziji, H.2    Bacchi, C.E.3    Gown, A.M.4
  • 13
    • 0141742109 scopus 로고    scopus 로고
    • Cdx2 protein expression in normal and malignant human tissues: An immunohistochemical survey using tissue microarrays
    • DOI 10.1097/01.MP.0000086073.92773.55
    • Moskaluk CA, Zhang H, Powell SM, et al. CDX-2 expression in normal and malignant human tissues: an immunohistochemical survey using tissue microarrays. Mod Pathol. 2003;16:913-919. (Pubitemid 37152021)
    • (2003) Modern Pathology , vol.16 , Issue.9 , pp. 913-919
    • Moskaluk, C.A.1    Zhang, H.2    Powell, S.M.3    Cerilli, L.A.4    Hampton, G.M.5    Frierson Jr., H.F.6
  • 15
    • 3242797249 scopus 로고    scopus 로고
    • Immunophenotypic differences between intestinal-type and low grade papillary sinonasal adenocarcinomas: An immunohistochemical study of 22 cases utilizing CDX-2 and MUC2
    • Cathro HP, Mills SE. Immunophenotypic differences between intestinal-type and low grade papillary sinonasal adenocarcinomas: an immunohistochemical study of 22 cases utilizing CDX-2 and MUC2. Am J Surg Pathol. 2004;28:1026-1032.
    • (2004) Am J Surg Pathol. , vol.28 , pp. 1026-1032
    • Cathro, H.P.1    Mills, S.E.2
  • 16
    • 0347419393 scopus 로고    scopus 로고
    • CDX2 immunoreactivity in primary and metastatic ovarian mucinous tumours
    • DOI 10.1007/s00428-003-0910-3
    • Fraggetta F, Pelosi G, Cafici A, et al. CDX-2 immunoreactivity in primary and metastatic ovarian mucinous tumours. Virchows Arch. 2003;443:782-786. (Pubitemid 38030633)
    • (2003) Virchows Archiv , vol.443 , Issue.6 , pp. 782-786
    • Fraggetta, F.1    Pelosi, G.2    Cafici, A.3    Scollo, P.4    Nuciforo, P.5    Viale, G.6
  • 17
    • 56149088548 scopus 로고    scopus 로고
    • Comprehensive evaluation of CDX-2 in invasive cervical adenocarcinomas: Immunopositivity in the absence of overt colorectal morphology
    • Sullivan LM, Smolkin ME, Frierson HF, et al. Comprehensive evaluation of CDX-2 in invasive cervical adenocarcinomas: immunopositivity in the absence of overt colorectal morphology. Am J Surg Pathol. 2008;32:1608-1612.
    • (2008) Am J Surg Pathol. , vol.32 , pp. 1608-1612
    • Sullivan, L.M.1    Smolkin, M.E.2    Frierson, H.F.3
  • 19
    • 0344737850 scopus 로고    scopus 로고
    • Primary Cervical Adenocarcinoma with Intestinal Differentiation and Colonic Carcinoma Metastatic to Cervix: An Investigation Using Cdx-2 and a Limited Immunohistochemical Panel
    • Raspollini MR, Baroni G, Taddei A, et al. Primary cervical adenocarcinoma with intestinal differentiation and colonic carcinoma metastatic to cervix: an investigation using cdx-2 and a limited immunohistochemical panel. Arch Pathol Lab Med. 2003;127:1586-1590. (Pubitemid 37517469)
    • (2003) Archives of Pathology and Laboratory Medicine , vol.127 , Issue.12 , pp. 1586-1590
    • Raspollini, M.R.1    Baroni, G.2    Taddei, A.3    Taddei, G.L.4
  • 20
    • 0036090767 scopus 로고    scopus 로고
    • Keratin expression in human tissues and neoplasms
    • DOI 10.1046/j.1365-2559.2002.01387.x
    • Chu PG, Weiss LM. Keratin expression in human tissues and neoplasms. Histopathology. 2002;40:403-439. (Pubitemid 34535443)
    • (2002) Histopathology , vol.40 , Issue.5 , pp. 403-439
    • Chu, P.G.1    Weiss, L.M.2
  • 21
    • 0029878961 scopus 로고    scopus 로고
    • Cytokeratins 7 and 20 and carcinoembryonic antigen in ovarian and colonic carcinoma
    • Berezowski K, Stastny J, Kornstein M. Cytokeratin 7 and 20 and carcinoembryonic antigen in ovarian and colonic carcinoma. Mod Pathol. 1996;9:426-429. (Pubitemid 26152008)
    • (1996) Modern Pathology , vol.9 , Issue.4 , pp. 426-429
    • Berezowski, K.1    Stastny, J.F.2    Kornstein, M.J.3
  • 24
    • 12344329808 scopus 로고    scopus 로고
    • Use of novel immunohistochemical markers expressed in colonic adenocarcinoma to distinguish primary ovarian tumors from metastatic colorectal carcinoma
    • DOI 10.1038/modpathol.3800260
    • Logani S, Oliva E, Amell PM, et al. Use of novel immunohistochemical markers expressed in colonic adenocarcinoma to distinguish primary ovarian tumors from metastatic colorectal carcinoma. Mod Pathol. 2005;18:19-25. (Pubitemid 40128090)
    • (2005) Modern Pathology , vol.18 , Issue.1 , pp. 19-25
    • Logani, S.1    Oliva, E.2    Arnell, P.M.3    Amin, M.B.4    Young, R.H.5
  • 27
    • 33748082975 scopus 로고    scopus 로고
    • Cytokeratins 7 and 20 in primary and secondary mucinous tumors of the ovary: Analysis of coordinate immunohistochemical expression profiles and staining distribution in 179 cases
    • DOI 10.1097/01.pas.0000213281.43036.bb, PII 0000047820060900000009
    • Vang R, Gown AM, Barry TS, et al. Cytokeratins 7 and 20 in primary and secondary mucinous tumors of the ovary: analysis of coordinate immunohistochemical expression profiles and staining distribution in 179 cases. Am J Surg Pathol. 2006;30:1130-1139. (Pubitemid 44299346)
    • (2006) American Journal of Surgical Pathology , vol.30 , Issue.9 , pp. 1130-1139
    • Vang, R.1    Gown, A.M.2    Barry, T.S.3    Wheeler, D.T.4    Yemelyanova, A.5    Seidman, J.D.6    Ronnett, B.M.7
  • 28
    • 33750304107 scopus 로고    scopus 로고
    • Immunohistochemical expression of CDX2 in primary ovarian mucinous tumors and metastatic mucinous carcinomas involving the ovary: Comparison with CK20 and correlation with coordinate expression of CK7
    • DOI 10.1038/modpathol.3800698, PII 3800698
    • Vang R, Gown AM, Wu LS, et al. Immunohistochemical expression of CDX-2 in primary ovarian mucinous tumors and metastatic mucinous carcinomas involving the ovary: comparison with CK20 and correlation with coordinate expression of CK7. Mod Pathol. 2006;19:1421-1428. (Pubitemid 44624160)
    • (2006) Modern Pathology , vol.19 , Issue.11 , pp. 1421-1428
    • Vang, R.1    Gown, A.M.2    Wu, L.-S.-F.3    Barry, T.S.4    Wheeler, D.T.5    Yemelyanova, A.6    Seidman, J.D.7    Ronnett, B.M.8
  • 29
    • 39349093993 scopus 로고    scopus 로고
    • Intestinal-type cervical adenocarcinoma in situ and adenocarcinoma exhibit a partial enteric immunophenotype with consistent expression of CDX2
    • DOI 10.1097/pgp.0b013e31815698e7, PII 0000434720080100000018
    • McCluggage WG, Shah R, Connolly LE, et al. Intestinal type cervical adenocarcinoma in situ and adenocarcinoma exhibit a partial enteric immunophenotype with consistent expression of CDX-2. Int J Gynecol Pathol. 2008;27:92-100. (Pubitemid 351627980)
    • (2008) International Journal of Gynecological Pathology , vol.27 , Issue.1 , pp. 92-100
    • McCluggage, W.G.1    Shah, R.2    Connolly, L.E.3    McBride, H.A.4
  • 32
    • 0031740497 scopus 로고    scopus 로고
    • Expression status of p16 protein is associated with human papillomavirus oncogenic potential in cervical and genital lesions
    • Sano T, Oyama T, Kashiwabara K, et al. Expression status of p16 protein is associated with human papillomavirus oncogenic potential in cervical and genital lesions. Am J Pathol. 1998;153:1741-1748. (Pubitemid 28550662)
    • (1998) American Journal of Pathology , vol.153 , Issue.6 , pp. 1741-1748
    • Sano, T.1    Oyama, T.2    Kashiwabara, K.3    Fukuda, T.4    Nakajima, T.5
  • 33
    • 0034898099 scopus 로고    scopus 로고
    • Cytokeratin subset immunostaining in rectal adenocarcinoma and normal anal glands
    • Ramalingam P, Hart WR, Goldblum JR. Cytokeratin subset immunostaining in rectal adenocarcinoma and normal anal glands. Arch Pathol Lab Med. 2001;125:1074-1077.
    • (2001) Arch Pathol Lab Med. , vol.125 , pp. 1074-1077
    • Ramalingam, P.1    Hart, W.R.2    Goldblum, J.R.3
  • 35
    • 0031889885 scopus 로고    scopus 로고
    • Perianal Paget's disease: A histologic and immunohistochemical study of 11 cases with and without associated rectal adenocarcinoma
    • Goldblum JR, Hart WR. Perianal Paget's disease: a histologic and immunohistochemical study of 11 cases with and without associated rectal adenocarcinoma. Am J Surg Pathol. 1998;22:170-179.
    • (1998) Am J Surg Pathol. , vol.22 , pp. 170-179
    • Goldblum, J.R.1    Hart, W.R.2
  • 36
    • 0032430608 scopus 로고    scopus 로고
    • Perianal Paget's disease: Distinguishing primary and secondary lesions using immunohistochemical studies including gross cystic disease fluid protein-15 and cytokeratin 20 expression
    • Nowak MA, Guerriere-Kovach P, Pathan A, et al. Perianal Paget's disease: distinguishing primary and secondary lesions using immunohistochemical studies including gross cystic disease fluid protein-15 and cytokeratin 20 expression. Arch Pathol Lab Med. 1998;122:1077-1081. (Pubitemid 29009399)
    • (1998) Archives of Pathology and Laboratory Medicine , vol.122 , Issue.12 , pp. 1077-1081
    • Nowak, M.A.1    Guerriere-Kovach, P.2    Pathan, A.3    Campbell, T.E.4    Deppisch, L.M.5
  • 37
    • 2942687852 scopus 로고    scopus 로고
    • Diagnostic utility of CDX-2 expression in separating metastatic gastrointestinal adenocarcinoma from other metastatic adenocarcinomas in fine needle aspiration cytology using cell block
    • Saad RS, Essig DL, Silverman JF, et al. Diagnostic utility of CDX-2 expression in separating metastatic gastrointestinal adenocarcinoma from other metastatic adenocarcinomas in fine needle aspiration cytology using cell block. Cancer. 2004;102:168-173.
    • (2004) Cancer , vol.102 , pp. 168-173
    • Saad, R.S.1    Essig, D.L.2    Silverman, J.F.3
  • 38
    • 66549088325 scopus 로고    scopus 로고
    • CDX-2, cytokeratins 7 and 20 immunoreactivity in rectal adenocarcinomas [published online ahead of print December 18, 2008]
    • Saad RS, Rowsell C, Khalifa MA, et al. CDX-2, cytokeratins 7 and 20 immunoreactivity in rectal adenocarcinomas [published online ahead of print December 18, 2008]. Appl Immunohistochem Mol Morphol. 2009;17:196-201.
    • (2009) Appl Immunohistochem Mol Morphol. , vol.17 , pp. 196-201
    • Saad, R.S.1    Rowsell, C.2    Khalifa, M.A.3
  • 39
    • 0346992299 scopus 로고    scopus 로고
    • The Value of Cdx2 Immunostaining in Differentiating Primary Ovarian Carcinomas from Colonic Carcinomas Metastatic to the Ovaries
    • DOI 10.1097/01.pgp.0000101141.31270.a0
    • Groisman GM, Meir A, Sabo E. The value of CDX-2 immunostaining in differentiating primary ovarian carcinomas from colonic carcinomas metastatic to the ovaries. Int J Gynecol Pathol. 2004;23:52-57. (Pubitemid 38018238)
    • (2004) International Journal of Gynecological Pathology , vol.23 , Issue.1 , pp. 52-57
    • Groisman, G.M.1    Meir, A.2    Sabo, E.3
  • 40
    • 0032920473 scopus 로고    scopus 로고
    • Adenocarcinomas metastatic to the liver: The value of cytokeratins 20 and 7 in the search for unknown primary tumors
    • DOI 10.1002/(SICI)1097-0142(19990101)85:1<171::AID-CNCR24>3.0.CO;2- V
    • Tot T. Adenocarcinomas metastatic to the liver: the value of cytokeratins 20 and 7 in the search for unknown primary tumors. Cancer. 1999;85:171-177. (Pubitemid 29031372)
    • (1999) Cancer , vol.85 , Issue.1 , pp. 171-177
    • Tot, T.1
  • 41
    • 14644442941 scopus 로고    scopus 로고
    • Synchronous and metachronous endocervical and ovarian neoplasms: Evidence supporting interpretation of the ovarian neoplasms as metastatic endocervical adenocarcinomas simulating primary ovarian surface epithelial neoplasms
    • DOI 10.1097/01.pas.0000152136.81771.12
    • Elishaev E, Gilks CB, Miller D, et al. Synchronous and metachronous endocervical and ovarian neoplasms: evidence supporting interpretation of the ovarian neoplasms as metastatic endocervical adenocarcinomas simulating primary ovarian surface epithelial neoplasms. Am J Surg Pathol. 2005;29:281-294. (Pubitemid 40321963)
    • (2005) American Journal of Surgical Pathology , vol.29 , Issue.3 , pp. 281-294
    • Elishaev, E.1    Gilks, C.B.2    Miller, D.3    Srodon, M.4    Kurman, R.J.5    Ronnett, B.M.6
  • 42
    • 1642494668 scopus 로고    scopus 로고
    • Distinction of Endocervical and Endometrial Adenocarcinomas: Immunohistochemical p16 Expression Correlated with Human Papillomavirus (HPV) DNA Detection
    • DOI 10.1097/00000478-200402000-00002
    • Ansari-Lari MA, Staebler A, Zaino RJ, et al. Distinction of endocervical and endometrial adenocarcinomas: immunohistochemical p16 expression correlated with human papillomavirus (HPV) DNA detection. Am J Surg Pathol. 2004;28:160-167. (Pubitemid 38124723)
    • (2004) American Journal of Surgical Pathology , vol.28 , Issue.2 , pp. 160-167
    • Ansari-Lari, M.A.1    Staebler, A.2    Zaino, R.J.3    Shah, K.V.4    Ronnett, B.M.5
  • 43
    • 34248177239 scopus 로고    scopus 로고
    • Distribution of human papillomavirus types in different histological subtypes of cervical adenocarcinoma
    • Hadzisejdć I, Krasević M, Haller H, et al. Distribution of human papillomavirus types in different histological subtypes of cervical adenocarcinoma. Coll Antropol. 2007;31(suppl 2):97-102.
    • (2007) Coll Antropol. , vol.31 , Issue.SUPPL. 2 , pp. 97-102
    • Hadzisejdć, I.1    Krasević, M.2    Haller, H.3
  • 44
    • 0142209277 scopus 로고    scopus 로고
    • The value of HPV DNA typing in the distinction between adenocarcinoma of endocervical and endometrial origin
    • DOI 10.1080/00313020310001602611
    • Plunkett M, Brestovac B, Thompson J, et al. The value of HPV DNA typing in the distinction between adenocarcinoma of endocervical and endometrial origin. Pathology. 2003;35:397-401. (Pubitemid 37310980)
    • (2003) Pathology , vol.35 , Issue.5 , pp. 397-401
    • Plunkett, M.K.1    Brestovac, B.2    Thompson, J.E.3    Sterrett, G.F.4    Filion, P.R.5    Smith, D.W.6    Frost, F.A.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.