Influence of intra- and extracellular acidification on free radical formation and mitochondria membrane potential in rat brain synaptosomes

Journal of Molecular Neuroscience

Volumn 49, Issue 1, 2013, Pages 211-222

  Pekun, Tatyana G ^a   Lemeshchenko, Valeriya V ^a   Lyskova, Tamara I ^a   Waseem, Tatyana V ^a   Fedorovich, Sergei V ^a  

^a INSTITUTE OF PHOTOBIOLOGY   (Belarus)

Author keywords

Acidosis; Ischemia; Mitochondria; Presynaptic; Superoxide anion; Synaptosomes

Indexed keywords

CARBONYL CYANIDE CHLOROPHENYLHYDRAZONE; HYDROETHIDINE; OXIDOREDUCTASE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; RHODAMINE 123; SUPEROXIDE DISMUTASE;

ACIDIFICATION; ANIMAL TISSUE; ARTICLE; BRAIN SYNAPTOSOME; CELL PH; ENZYME ACTIVITY; HEMISPHERE; MALE; MEMBRANE DEPOLARIZATION; MITOCHONDRIAL MEMBRANE POTENTIAL; NONHUMAN; OXIDATIVE STRESS; PH; RAT; SYNAPTIC TRANSMISSION;

ACIDOSIS; AMILORIDE; ANIMALS; BRAIN; EXTRACELLULAR SPACE; FLUORESCENT DYES; HYDROGEN-ION CONCENTRATION; INTRACELLULAR SPACE; MALE; MEMBRANE POTENTIAL, MITOCHONDRIAL; MITOCHONDRIA; OXIDATIVE STRESS; RATS; RATS, WISTAR; SUPEROXIDES; SYNAPTOSOMES; UNCOUPLING AGENTS; VOLTAGE-SENSITIVE DYE IMAGING;

RATTUS;

EID: 84871981451     PISSN: 08958696     EISSN: 15591166     Source Type: Journal    
DOI: 10.1007/s12031-012-9913-3     Document Type: Article

References (60)

1. Alekseenko AV, Waseem TV, Fedorovich SV (2008) Ferritin, a protein containing iron nanoparticles, induces reactive oxygen species formation and inhibits glutamate uptake in rat brain synaptosomes. Brain Res 1241:193-200
2. Alekseenko AV, Lemeshchenko VV, Pekun TG, Waseem TV, Fedorovich SV (2012) Glutamate-induced free radical formation in rat brain synaptosomes is not dependent on intrasynaptosomal mitochondria membrane potential. Neurosci Lett 513:238-242
3. Behrens MM, Ali SS, Dao DN et al (2007) Ketamine-induced loss of phenotype of fast-spiking interneurons is mediated by NADPH-oxidase. Science 318:1645-1647
4. Bindokas VP, Jordan J, Lee CC, Miller RJ (1996) Superoxide production in rat hippocampal neurons: selective imaging with hydroethidine. J Neurosci 16:1324-1336
5. Bolay H, Gursoy-Ozdemir Y, Sara Y, Onur R, Can A, Dalkara T (2002) Persistent defect in transmitter release and synapsin phosphorylation in cerebral cortex after transient moderate ischemic injury. Stroke 33:1369-1375
6. Bralet J, Bouvier C, Schreiber L, Boquilon M (1991) Effect of acidosis on lipid peroxidation in brain slices. Brain Res 539:175-177
7. Bralet J, Schreiber L, Bouviern C (1992) Effect of acidosis and anoxia on iron delocalization from brain homogenates. Biochem Pharmacol 43:979-983
8. Chesler M (2003) Regulation and modulation of pH in the brain. Physiol Rev 83:1183-1221
9. Chinopoulos C, Tretter L, Adam-Vizi V (1999) Depolarization of in situ mitochondria due to hydrogen peroxide-induced oxidative stress in nerve terminals: inhibition of á-ketoglutarate dehydrogenase. J Neurochem 73:220-228
10. Correia SC, Carvalho C, Cardoso S et al (2010) Mitochondrial preconditioning: a potential neuroprotective strategy. Front Aging Neurosci 2:A138
11. Crowell JW, Kaufmann BN (1961) Changes in tissue pH after cardiac arrest. Am J Physiol 200:743-745
12. Deyev IE, Sohet F, Vassilenko KP et al (2011) Insulin receptor-related receptor as an extracellular alkali sensor. Cell Metab 13:679-689
13. Drapeau P, Nachshen DA (1988) Effects of lowering extracellular and cytosolic pH on calcium fluxes, cytosolic calcium levels and transmitter release in presynaptic nerve terminals isolated from rat brain. J Gen Physiol 91:305-315
14. Eccles RM, Loyning Y, Oshima T (1966) Effects of hypoxia on the monosynaptic reflex pathway in the cat spinal cord. J Neurophysiol 29:315-331
15. Fedorovich SV, Aksentsev SL, Konev SV (1996) Acidosis inhibits calcium accumulation in intrasynaptosomal mitochondria. Acta Neurobiol Exp 56:703
16. Fedorovich SV, Aksentsev SL, Lyskova TI, Kaler GV, Fedulov AS, Konev SV (1997) Effect of acidosis on membrane potential and calcium transport in rat brain synaptosomes. Biofizika 42:412-416 (in Russian)
17. Fedorovich SV, Kaler GV, Konev SV (2003) Effect of low pH on glutamate uptake and release in isolated presynaptic endings from rat brain. Neurochem Res 28:715-721
18. Giniatullin AR, Darios F, Shakirzyanova A, Davletov B, Giniatullin R (2006) SNAP25 is a pre-synaptic target for the depressant action of reactive oxygen species on transmitter release. J Neurochem 98:1789-1797
19. Hajos F (1975) An improved method for the preparation of synaptosomal fractions in high purity. Brain Res 93:485-489
20. Halliwell B (2006) Oxidative stress and neurodegeneration: where are we now? J Neurochem 97:1634-1658
21. Herschkowitz N, Katchman AN, Veregge S (1993) Site of synaptic depression during hypoxia: a patch-clamp analysis. J Neurophysiol 69:432-441
22. Hofmeijer J, van Putten MJAM (2012) Ischemic cerebral damage. An appraisal of synaptic failure. Stroke 43:607-615
23. Hsu KS, Liang YC, Huang CC (2000) Influence of an extracellular acidosis on excitatory synaptic transmission and long-term potentiation in the CA1 region of rat hippocampal slices. J Neurosci Res 62:403-415
24. Hutchinson DS, Csikasz RI, Yamamoto DL et al (2007) Diphenylene iodinium stimulates glucose uptake in skeletal muscle cells through mitochondrial complex I inhibition and activation of AMP-activated protein kinase. Cell Signal 19:1610-1620
25. Isaev NK, Stelmashook EV, Plotnikov EY et al (2008) Role of acidosis, NMDA receptors, and acid-sensitive ion channel 1a (ASIC1a) in neuronal death induced by ischemia. Biochem Mosc 73:1171-1175
26. Kalyanaraman B, Darley-Usmar V, Davies KJA et al (2012) Measuring reactive oxygen species and nitrogen species with fluorescent probes: challenges and limitations. Free Rad Biol Med 52:1-6
27. Keating DI (2008) Mitochondrial dysfunction, oxidative stress, regulation of exocytosis and their relevance to neurodegenerative diseases. J Neurochem 104:298-305
28. Kellenberger S, Schild L (2002) Epithelial sodium channel/degenerin family of ion channels: a variety of functions for a shared structure. Physiol Rev 82:735-767
29. Kraig RP, Chesler M (1990) Astrocytic acidosis in hyperglycemic and complete ischemia. J Cereb Blood Flow Metab 10:104-114
30. Krishtal OA, Pidoplichko VI (1981) A receptor for protons in the membrane of sensory neurons may participate in nociception. Neuroscience 6:2599-2601
31. LeBel CP, Bondy SC (1990) Sensitive and rapid quantitation of oxygen reactive species formation in rat synaptosomes. Neurochem Int 17:435-440
32. Lowry O, Rosenbrough H, Farr H, Randall R (1951) Protein measurements with folin reagent. J Biol Chem 193:265-279
33. Lyskova TI, Aksentsev SL, Fedorovich SV et al (1997) Effect of ischemic damage factors on lipid peroxidation in rat brain synaptosomes. Biofizika 42:408-411 (In Russian)
34. Misra H, Fridovich I (1972) The role of superoxide anion in the autooxidation of epinephrine and simple assay for superoxide dismutase. J Biol Chem 247:3170-3175
35. Mittmann T, Qu M, Zilles K, Luhmann HI (1998) Long-term cellular dysfunction after focal cerebral ischemia: in vitro analysis. Neuroscience 85:15-27
36. + on the electrical properties of excitable cells. Annu Rev Neurosci 7:257-278
37. Nachshen DA, Drapeau P (1988) The regulation of cytosolic pH in isolated presynaptic nerve terminals from rat brain. J Gen Physiol 91:289-303
38. Neumann-Haefilin T, Witte OW (2000) Periinfarct and remote excitability changes after transient middle cerebral artery occlusion. J Cereb Blood Flow Metab 20:45-52
39. Obara M, Szeliga M, Albrecht J (2008) Regulation of pH in the mammalian central nervous system under normal and pathological conditions: fact and hypotheses. Neurochem Int 52:905-919
40. Pekun TG, Waseem TV, Fedorovich SV (2012) Extracellular acidification leads to reactive oxygen species formation in rat brain synaptosomes. Biofizika 57:253-257 (in Russian)
41. Ravati A, Ahlemeyer B, Becker A, Klumpp S, Krieglstein J (2001) Preconditioning-induced neuroprotection is mediated by reactive oxygen species and activation of the transcription factor nuclear factor kappaB. J Neurochem 78:909-919
42. Reynolds IJ, Hastings TG (1995) Glutamate induces the production of reactive oxygen species in cultured forebrain neurons following NMDA receptor activation. J Neurosci 15:3318-3327
43. 2+: molecular determinants and functional consequences. Physiol Rev 86:369-408
44. 2+ fluxes in rat brain synaptosomes. Biochem Biophys Res Com 242:123-128
45. Schrimpf SP, Meskenaite V, Brunner E et al (2005) Proteomic analysis of synaptosomes using isotope-coded affinity tags and mass spectrometry. Proteomics 5:2631-2641
46. Selivanov VA, Zeak JA, Roca J, Cascante M, Trucco M, Votyakova TV (2008) The role of external and matrix pH in mitochondrial reactive oxygen species generation. J Biol Chem 288:29292-29300
47. Setsukinai T-I, Urano Y, Kakinuma K, Majima HJ, Nagano T (2003) Development of novel fluorescence probes that can reliably detect reactive oxygen species and distinguish specific species. J Biol Chem 278:3170-3175
48. Siesjo BK, Bendek G, Koide T, Westerberg E, Wieloch T (1985) Influence of acidosis on lipid peroxidation in brain tissues in vitro. J Cereb Blood Flow Metab 5:253-258
49. Sudhof TC (2004) The synaptic vesicle cycle. Annu Rev Neurosci 27:509-547
50. Thorn WG, Heitman R (1954) pH der Gehirunde vom Kaninchen in situ wahrend perakuter, totaler Ischaemie, reiner Anoxie und in der Erholung. Pflug Arch 218:501-510
51. Tombaugh GC, Sapolsky RM (1993) Evolving concepts about the role of acidosis in ischemic neuropathology. J Neurochem 61:793-803
52. Tretter L, Chinopoulos C, Adam-Vizi V (1997) Enhances depolarization-evoked calcium signal and reduced [ATP]/[ADP] ratio are unrelated events induced by oxidative stress in synaptosomes. J Neurochem 69:2529-2537
53. Voglis G, Tavernarakis N (2008) A synaptic DEG/ENaC ion channel mediates learning in C. elegans by facilitating dopamine signaling. EMBO J 27:3288-3299
54. Waseem TV, Konev SV, Fedorovich SV (2004) Influence of hypotonic shock on glutamate and GABA uptake in rat brain synaptosomes. Neurochem Res 29:1653-1658
55. Waseem TV, Rakovich AA, Lavrukevich TV, Konev SV, Fedorovich SV (2005) Calcium regulates the mode of exocytosis induced by hypotonic shock in isolated neuronal presynaptic endings. Neurochem Int 46:235-242
56. Waseem TV, Kolos VA, Lapatsina LP, Fedorovich SV (2007) Hypertonic shrinking but not hypotonic swelling increases sodium concentration in rat brain synaptosomes. Brain Res Bull 73:135-142
57. Wind S, Beuerlin K, Eucker T et al (2010) Comparative pharmacology of chemically distinct NADPH oxidase inhibitors. Br J Pharmacol 161:885-898
58. Xiong Z-G, Zhu X-M, Chu X-P et al (2004) Neuroprotection in ischemia: blocking calcium-permeable acid-sensing ion channels. Cell 118:687-698
59. Yates CM, Butterworth J, Tennant MC, Gordon A (1990) Enzyme activities in relation to pH and lactate in postmortem brain in Alzheimer-type and other dementia. J Neurochem 55:1624-1630
60. Ying W, Han S-K, Miller JW, Swanson RA (1999) Acidosis potentiates oxidative neuronal death by multiple mechanisms. J Neurochem 73:1549-1556