Diphenylene iodonium stimulates glucose uptake in skeletal muscle cells through mitochondrial complex I inhibition and activation of AMP-activated protein kinase

Cellular Signalling

Volumn 19, Issue 7, 2007, Pages 1610-1620

  Hutchinson, Dana S ^a,b   Csikasz, Robert I ^a   Yamamoto, Daniel L ^a   Shabalina, Irina G ^a   Wikström, Per ^c   Wilcke, Mona ^c   Bengtsson, Tore ^a  

^a STOCKHOLM UNIVERSITY   (Sweden)

^b MONASH UNIVERSITY   (Australia)

^c Glucox Biotech AB   (Sweden)

Author keywords

AMPK; DPI; Glucose uptake; L6; Mitochondria; NADPH oxidase; Skeletal muscle

Indexed keywords

2 MORPHOLINO 8 PHENYLCHROMONE; ADENOSINE TRIPHOSPHATE; APOCYNIN; BENZIMIDAZOLE DERIVATIVE; CHIMERIC PROTEIN; DIPHENYLIODONIUM SALT; GLUCOSE; GLYCOPROTEIN GP 91; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; MESSENGER RNA; METFORMIN; NEUTRAL INSULIN; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; PROTEIN NOX4; PROTEIN P22; PROTEIN P47; PROTEIN TAT GP91DS; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASE (UBIQUINONE); STO 609; TRANSACTIVATOR PROTEIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; DIABETES MELLITUS; DRUG MECHANISM; ENZYME ACTIVATION; ENZYME INHIBITION; GLUCOSE BLOOD LEVEL; GLUCOSE HOMEOSTASIS; GLUCOSE TRANSPORT; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; RAT; SKELETAL MUSCLE;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ACETOPHENONES; ACETYL-COA CARBOXYLASE; ADENOSINE TRIPHOSPHATE; ANIMALS; CELL DIFFERENTIATION; ELECTRON TRANSPORT COMPLEX I; ENZYME ACTIVATION; ENZYME INHIBITORS; GENE EXPRESSION REGULATION, ENZYMOLOGIC; GLUCOSE; GLYCOGEN; GLYCOGEN SYNTHASE KINASE 3; GLYCOPROTEINS; MICE; MITOCHONDRIA; MULTIENZYME COMPLEXES; MUSCLE, SKELETAL; NADPH OXIDASE; ONIUM COMPOUNDS; OXYGEN CONSUMPTION; PHOSPHORYLATION; PROTEIN-SERINE-THREONINE KINASES; RATS; RNA, MESSENGER; SERINE;

RODENTIA;

EID: 34249277087     PISSN: 08986568     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cellsig.2007.02.006     Document Type: Article

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