메뉴 건너뛰기




Volumn 38, Issue 1, 2013, Pages 4-10

Immunohistochemical profile of NF-κB/p50, NF-κB/p65, MMP-9, MMP-2, and u-PA in experimental cervical spondylotic myelopathy

Author keywords

cervical spondylotic myelopathy; glial cells; MMP 2; MMP 9; neurons; NF B; spinal cord; u PA

Indexed keywords

GELATINASE A; GELATINASE B; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; TRANSCRIPTION FACTOR RELA; UROKINASE;

EID: 84871977280     PISSN: 03622436     EISSN: 15281159     Source Type: Journal    
DOI: 10.1097/BRS.0b013e318261ea6f     Document Type: Article
Times cited : (35)

References (51)
  • 1
    • 0032535533 scopus 로고    scopus 로고
    • A review of the pathophysiology of cervical spondylotic myelopathy with insights for potential novel mechanisms drawn from traumatic spinal cord injury
    • DOI 10.1097/00007632-199812150-00012
    • Fehlings MG, Skaf G. A review of the pathophysiology of cervical spondylotic myelopathy with insights for potential novel mechanisms drawn from traumatic spinal cord injury. Spine 1998; 23: 2730-7. (Pubitemid 29013985)
    • (1998) Spine , vol.23 , Issue.24 , pp. 2730-2737
    • Fehlings, M.G.1    Skaf, G.2
  • 3
    • 34250898562 scopus 로고    scopus 로고
    • NF-κB as a potential molecular target for cancer therapy
    • Lee CH, Jeon YT, Kim SH, et al. NF-κ B as a potential molecular target for cancer therapy. Biofactors 2007; 29: 19-35. (Pubitemid 46985299)
    • (2007) BioFactors , vol.29 , Issue.1 , pp. 19-35
    • Lee, C.H.1    Jeon, Y.-T.2    Kim, S.-H.3    Song, Y.-S.4
  • 4
    • 0035174615 scopus 로고    scopus 로고
    • Series introduction: The transcription factor NF-κ B and human disease
    • Baldwin AS, Jr. Series introduction: the transcription factor NF-κ B and human disease. J Clin Invest 2001; 107: 3-6.
    • (2001) J Clin Invest , vol.107 , pp. 3-6
    • Baldwin Jr., A.S.1
  • 5
    • 33645999706 scopus 로고    scopus 로고
    • NF-κ B and IKK as therapeutic targets in cancer
    • Kim HJ, Hawke N, Baldwin AS. NF-κ B and IKK as therapeutic targets in cancer. Cell Death Differ 2001; 13: 738-47.
    • (2001) Cell Death Differ , vol.13 , pp. 738-747
    • Kim, H.J.1    Hawke, N.2    Baldwin, A.S.3
  • 6
    • 0026896029 scopus 로고
    • The matrix-degrading metalloproteinases
    • Matrisian LM. The matrix-degrading metalloproteinases. Bio Essays 1992; 14: 455-63.
    • (1992) Bio Essays , vol.14 , pp. 455-463
    • Matrisian, L.M.1
  • 7
    • 0035500490 scopus 로고    scopus 로고
    • The many faces of metalloproteases: Cell growth, invasion, angiogenesis, and metastasis
    • Chang C, Werb Z. The many faces of metalloproteases: cell growth, invasion, angiogenesis, and metastasis. Trends Cell Biol 2001; 11: S37-43.
    • (2001) Trends Cell Biol , vol.11
    • Chang, C.1    Werb, Z.2
  • 9
    • 0035405886 scopus 로고    scopus 로고
    • Metalloproteinases in biology and pathology of the nervous system
    • DOI 10.1038/35081571
    • Yong VW, Power C, Forsyth P, et al. Metalloproteinases in biology and pathology of the nervous system. Nat Rev Neurosci 2001; 2: 502-11. (Pubitemid 33676585)
    • (2001) Nature Reviews Neuroscience , vol.2 , Issue.7 , pp. 502-511
    • Yong, V.W.1    Power, C.2    Forsyth, P.3    Edwards, D.R.4
  • 10
    • 19344366798 scopus 로고    scopus 로고
    • Gelatinase-mediated migration and invasion of cancer cells
    • DOI 10.1016/j.bbcan.2005.03.001, PII S0304419X05000077
    • Bjorklund M, Koivunen E. Gelatinase-mediated migration and invasion of cancer cells. Biochim Biophys Acta 2005; 1755: 37-69. (Pubitemid 40720240)
    • (2005) Biochimica et Biophysica Acta - Reviews on Cancer , vol.1755 , Issue.1 , pp. 37-69
    • Bjorklund, M.1    Koivunen, E.2
  • 12
    • 0028973084 scopus 로고
    • Tumor necrosis factor-alpha-induced gelatinase B causes delayed opening of the blood-brain barrier: An expanded therapeutic window
    • DOI 10.1016/0006-8993(95)01089-0
    • Rosenberg GA, Estrada E Y, Dencoff JE, et al. Tumor necrosis factor-α-induced gelatinase B causes delayed opening of the blood-brain barrier (BBB): an expanded therapeutic window. Brain Res 1995; 703: 151-5. (Pubitemid 3013581)
    • (1995) Brain Research , vol.703 , Issue.1-2 , pp. 151-155
    • Rosenberg, G.A.1    Estrada, E.Y.2    Dencoff, J.E.3    Stetler-Stevenson, W.G.4
  • 13
    • 0029889674 scopus 로고    scopus 로고
    • Effect of steroids on CSF matrix metalloproteinases in multiple sclerosis: Relation to blood-brain barrier injury
    • Rosenberg GA, Dencoff JE, Correa N, Jr, et al. Effect of steroids on CSF matrix metalloproteinases in multiple sclerosis: relation to BBB injury. Neurology 1996; 46: 1626-32. (Pubitemid 26185784)
    • (1996) Neurology , vol.46 , Issue.6 , pp. 1626-1632
    • Rosenberg, G.A.1    Dencoff, J.E.2    Correa Jr., N.3    Reiners, M.4    Ford, C.C.5
  • 14
    • 0031693557 scopus 로고    scopus 로고
    • Matrix metalloproteinases and TIMPs are associated with blood-brain barrier opening after reperfusion in rat brain
    • Rosenberg GA, Estrada EY, Dencoff JE. MMPs and TIMPs are associated with BBB opening after reperfusion in rat brain. Stroke 1998; 29: 2189-95. (Pubitemid 28443538)
    • (1998) Stroke , vol.29 , Issue.10 , pp. 2189-2195
    • Rosenberg, G.A.1    Estrada, E.Y.2    Dencoff, J.E.3
  • 15
    • 0036758650 scopus 로고    scopus 로고
    • Matrix metalloproteinases limit functional recovery after spinal cord injury by modulation of early vascular events
    • Noble LJ, Donovan F, Igarashi T, et al. MMPs limit functional recovery after spinal cord injury by modulation of early vascular events. J Neurosci 2002; 22: 7526-35. (Pubitemid 35386354)
    • (2002) Journal of Neuroscience , vol.22 , Issue.17 , pp. 7526-7535
    • Noble, L.J.1    Donovan, F.2    Igarashi, T.3    Goussev, S.4    Werb, Z.5
  • 16
    • 0035194622 scopus 로고    scopus 로고
    • Matrix metalloproteinase inhibition prevents oxidative stress-associated blood-brain barrier disruption after transient focal cerebral ischemia
    • Gasche Y, Copin JC, Sugawara T, et al. MMP inhibition prevents oxidative stress-associated BBB disruption after transient focal cerebral ischemia. J Cereb Blood Flow Metab 2001; 21: 1393-400. (Pubitemid 33120943)
    • (2001) Journal of Cerebral Blood Flow and Metabolism , vol.21 , Issue.12 , pp. 1393-1400
    • Gasche, Y.1    Copin, J.-C.2    Sugawara, T.3    Fujimura, M.4    Chan, P.H.5
  • 17
    • 0141869839 scopus 로고    scopus 로고
    • Neurodegeneration in striatum induced by the mitochondrial toxin 3-nitropropionic acid: Role of matrix metalloproteinase-9 in early blood-brain barrier disruption?
    • Kim GW, Gasche Y, Grzeschik S, et al. Neurodegeneration in stri-atum induced by the mitochondrial toxin 3-nitropropionic acid: role of MMP-9 in early BBB disruption? J Neurosci 2003; 23: 8733-42. (Pubitemid 37176654)
    • (2003) Journal of Neuroscience , vol.23 , Issue.25 , pp. 8733-8742
    • Kim, G.W.1    Gasche, Y.2    Grzeschik, S.3    Copin, J.-C.4    Maier, C.M.5    Chan, P.H.6
  • 18
    • 0026442957 scopus 로고
    • Gelatinase in the cerebrospi-nal fluid of patients with multiple sclerosis and other inflammatory neurological disorders
    • Gijbels K, Masure S, Carton H, et al. Gelatinase in the cerebrospi-nal fluid of patients with multiple sclerosis and other inflammatory neurological disorders. J Neuroimmunol 1992; 41: 29-34.
    • (1992) J Neuroimmunol , vol.41 , pp. 29-34
    • Gijbels, K.1    Masure, S.2    Carton, H.3
  • 19
    • 0027368518 scopus 로고
    • Gelatinase B is present in the cerebrospinal fluid during experimental autoimmune encephalomyelitis and cleaves myelin basic protein
    • DOI 10.1002/jnr.490360409
    • Gijbels K, Proost P, Masure S, et al. Gelatinase B is present in the cere-brospinal fluid during experimental autoimmune encephalomyelitis and cleaves myelin basic protein. J Neurosci Res 1993; 36: 432-40. (Pubitemid 23326323)
    • (1993) Journal of Neuroscience Research , vol.36 , Issue.4 , pp. 432-440
    • Gijbels, K.1    Proost, P.2    Masure, S.3    Carton, H.4    Billiau, A.5    Opdenakker, G.6
  • 20
  • 22
    • 0035478029 scopus 로고    scopus 로고
    • Effects of matrix metalloproteinase-9 gene knock-out on the proteolysis of blood-brain barrier and white matter components after cerebral ischemia
    • Asahi M, Wang X, Mori T, et al. Effects of matrix metalloprotein-ase-9 gene knock-out on the proteolysis of blood-brain barrier and white matter components after cerebral ischemia. J Neurosci 2001; 21: 7724-32. (Pubitemid 32904971)
    • (2001) Journal of Neuroscience , vol.21 , Issue.19 , pp. 7724-7732
    • Asahi, M.1    Wang, X.2    Mori, T.3    Sumii, T.4    Jung, J.-C.5    Moskowitz, M.A.6    Fini, M.E.7    Lo, E.H.8
  • 25
    • 32344433332 scopus 로고    scopus 로고
    • Role of intracellular S100A4 for migration of rat astrocytes
    • DOI 10.1002/glia.20284
    • Takenaga K, Kozlova EN. Role of intracellular S100A4 for migration of rat astrocytes. Glia 2006; 53: 313-21. (Pubitemid 43221352)
    • (2006) GLIA , vol.53 , Issue.3 , pp. 313-321
    • Takenaga, K.1    Kozlova, E.N.2
  • 27
    • 0033545342 scopus 로고    scopus 로고
    • Acute-phase proteins and other systemic responses to inflammation
    • DOI 10.1056/NEJM199902113400607
    • Gabay C, Kushner I. Acute-phase proteins and other systemic responses to inflammation. N Engl J Med 1999;340:448-54. (Pubitemid 29084777)
    • (1999) New England Journal of Medicine , vol.340 , Issue.6 , pp. 448-454
    • Gabay, C.1    Kushner, I.2
  • 28
    • 25144499286 scopus 로고    scopus 로고
    • A role for the plasminogen activator system in inflammation and neurodegeneration in the central nervous system during experimental allergic encephalomyelitis
    • East E, Baker D, Pryce G, et al. A role for the plasminogen activator system in inflammation and neurodegeneration in the central nervous system during experimental allergic encephalomyelitis. Am J Pathol 2005;167:545-54. (Pubitemid 43026108)
    • (2005) American Journal of Pathology , vol.167 , Issue.2 , pp. 545-554
    • East, E.1    Baker, D.2    Pryce, G.3    Lijnen, H.R.4    Cuzner, M.L.5    Gveric, D.6
  • 30
    • 80455164671 scopus 로고    scopus 로고
    • New experimental rabbit animal model for CSM
    • Klironomos G, Karadimas S, Mavrakis A, et al. New experimental rabbit animal model for CSM. Spinal Cord 2011; 49: 1097-102.
    • (2011) Spinal Cord , vol.49 , pp. 1097-1102
    • Klironomos, G.1    Karadimas, S.2    Mavrakis, A.3
  • 31
    • 26244445240 scopus 로고    scopus 로고
    • NF-κ in the survival and plasticity of neurons
    • Mattson M P. NF-κ in the survival and plasticity of neurons. Neurochem Res 2005; 30: 883-93.
    • (2005) Neurochem Res , vol.30 , pp. 883-893
    • Mattson, M.P.1
  • 32
  • 33
    • 0030697366 scopus 로고    scopus 로고
    • Reactive astrocytes: Cellular and molecular cues to biological function
    • DOI 10.1016/S0166-2236(97)01139-9
    • Ridet JL, Malhotra SK, Privat A, et al. Reactive astrocytes: cellular and molecular cues to biological function. Trends Neurosci 1997; 20: 570-7. (Pubitemid 27508969)
    • (1997) Trends in Neurosciences , vol.20 , Issue.12 , pp. 570-577
    • Ridet, J.L.1    Malhotra, S.K.2    Privat, A.3    Gage, F.H.4
  • 34
    • 0033216123 scopus 로고    scopus 로고
    • Cellular and molecular mechanisms of glial scarring and progressive cavitation: In vivo and in vitro analysis of inflammation-induced secondary injury after CNS trauma
    • Fitch MT, Doller C, Combs CK, et al. Cellular and molecular mechanisms of glial scarring and progressive cavitation: in vivo and in vitro analysis of inflammation-induced secondary injury after CNS trauma. J Neurosci 1999; 19: 8182-98. (Pubitemid 30226738)
    • (1999) Journal of Neuroscience , vol.19 , Issue.19 , pp. 8182-8198
    • Fitch, M.T.1    Doller, C.2    Combs, C.K.3    Landreth, G.E.4    Silver, J.5
  • 35
    • 0035863456 scopus 로고    scopus 로고
    • Modulating astrogliosis after neurotrauma
    • DOI 10.1002/1097-4547(20010115)63:2<109::AID-JNR1002>3.0.CO;2-J
    • McGraw J, Hiebert GW, Steeves JD. Modulating astrogliosis after neurotrauma. J Neurosci Res 2001; 63: 109-15. (Pubitemid 32041861)
    • (2001) Journal of Neuroscience Research , vol.63 , Issue.2 , pp. 109-115
    • McGraw, J.1    Hiebert, G.W.2    Steeves, J.D.3
  • 36
    • 84885836421 scopus 로고    scopus 로고
    • Requirement of functional ryanodine receptor type 3 for astrocyte migration
    • Matyash M, Matyash V, Nolte C, et al. Requirement of functional ryanodine receptor type 3 for astrocyte migration. FASEB J 2005;302005; 30: 883-93.
    • (2005) FASEB J , vol.30 , pp. 883-893
    • Matyash, M.1    Matyash, V.2    Nolte, C.3
  • 37
    • 58149379612 scopus 로고    scopus 로고
    • MMP-9 facilitates glial scar formation in the injured spinal cord
    • Hsu JY, Bourguignon LY, Adams CM, et al. MMP-9 facilitates glial scar formation in the injured spinal cord. J Neurosci 2008; 28: 13467-77.
    • (2008) J Neurosci , vol.28 , pp. 13467-13477
    • Hsu, J.Y.1    Bourguignon, L.Y.2    Adams, C.M.3
  • 38
    • 0141497935 scopus 로고    scopus 로고
    • Differential temporal expression of MMPs after spinal cord injury: Relationship to revascularization and wound healing
    • Goussev S, Hsu JY, Lin Y, et al. Differential temporal expression of MMPs after spinal cord injury: relationship to revascularization and wound healing. J Neurosurg Spine 2003; 99: 188-97.
    • (2003) J Neurosurg Spine , vol.99 , pp. 188-197
    • Goussev, S.1    Hsu, J.Y.2    Lin, Y.3
  • 40
  • 41
    • 0035156633 scopus 로고    scopus 로고
    • TNF-α stimulates activation of pro-MMP2 in human skin through NF-κB mediated induction of MT1-MMP
    • Han YP, Tuan TL, Wu H, et al. F-α stimulates activation of pro-MMP-2 in human skin through NF-κ B mediated induction of MT1-MMP. J Cell Sci 2001; 114: 131-9. (Pubitemid 32118063)
    • (2001) Journal of Cell Science , vol.114 , Issue.1 , pp. 131-139
    • Han, Y.-P.1    Tuan, T.-L.2    Wu, H.3    Hughes, M.4    Garner, W.L.5
  • 43
    • 0028302061 scopus 로고
    • Elevated levels of plasminogen activators in the pathogenesis of delayed radiation damage in rat cervical spinal cord in vivo
    • DOI 10.2307/3578687
    • Sawaya R, Rayford A, Kono S, et al. Elevated levels of plasminogen activators in the pathogenesis of delayed radiation damage in rat cervical spinal cord in vivo. Radiat Res 1994; 138: 386-91. (Pubitemid 24181222)
    • (1994) Radiation Research , vol.138 , Issue.3 , pp. 386-391
    • Sawaya, R.1    Rayford, A.2    Kono, S.3    Ang, K.K.4    Feng, Y.5    Stephens, L.C.6    Rao, J.S.7
  • 44
    • 72049085794 scopus 로고    scopus 로고
    • Role of plasminogen activator in spinal cord remodeling after spinal cord injury
    • Seeds NW, Akison L, Minor K. Role of plasminogen activator in spinal cord remodeling after spinal cord injury. Respir Physiol Neurobiol 2009; 169: 141-9.
    • (2009) Respir Physiol Neurobiol , vol.169 , pp. 141-149
    • Seeds, N.W.1    Akison, L.2    Minor, K.3
  • 45
    • 0031596140 scopus 로고    scopus 로고
    • Nuclear factor κB/p50 activates an element in the distal matrix metalloproteinase 1 promoter in interleukin-1β-stimulated synovial fibroblasts
    • DOI 10.1002/1529-0131(199811)41:11<1987::AID-ART14>3.0.CO;2-8
    • Vincenti MP, Coon CI, Brinckerhoff CE. NF-κ B/p50 activates an element in the distal MMP-1 promoter in interleukin-1beta-stimulated synovial fibroblasts. Arthritis Rheum 1998; 41: 1987-94. (Pubitemid 28506689)
    • (1998) Arthritis and Rheumatism , vol.41 , Issue.11 , pp. 1987-1994
    • Vincenti, M.P.1    Coon, C.I.2    Brinckerhoff, C.E.3
  • 46
    • 23044455714 scopus 로고    scopus 로고
    • Osteopontin: It's role in regulation of cell motility and nuclear factor κB-mediated urokinase type plasminogen activator expression
    • DOI 10.1080/15216540500159424
    • Das R, Philip S, Mahabeleshwar GH, et al. Osteopontin: its role in regulation of cell motility an nuclear factor kappa B-mediated urokinase type plasminogen activator expression. IUBMB Life 2005; 57: 441-7. (Pubitemid 41073126)
    • (2005) IUBMB Life , vol.57 , Issue.6 , pp. 441-447
    • Das, R.1    Philip, S.2    Mahabeleshwar, G.H.3    Bulbule, A.4    Kundu, G.C.5
  • 47
    • 2942717090 scopus 로고    scopus 로고
    • Signaling pathways responsible for cancer cell invasion as targets for cancer therapy
    • DOI 10.2174/1568009043332961
    • Sliva D. Signaling pathways responsible for cancer cell invasion as targets for cancer therapy. Curr Cancer Drug Targets 2004; 4: 327-36. (Pubitemid 38797244)
    • (2004) Current Cancer Drug Targets , vol.4 , Issue.4 , pp. 327-336
    • Sliva, D.1
  • 48
    • 0028970647 scopus 로고
    • Inhibition of NF-kappa B-RelA expression by antisense oligodeoxynucleotides suppresses synthesis of urokinase-type plasminogen activator (uPA) but not its inhibitor PAI-1
    • Reuning U, Wilhelm O, Nishiguchi T, et al. Inhibition of NF-kappa B-RelA expression by antisense oligodeoxynucleotides suppresses synthesis of urokinase-type plasminogen activator (uPA) but not its inhibitor PAI-1. Nucleic Acids Res 1995; 23: 3887-93.
    • (1995) Nucleic Acids Res , vol.23 , pp. 3887-3893
    • Reuning, U.1    Wilhelm, O.2    Nishiguchi, T.3
  • 49
    • 34248178375 scopus 로고    scopus 로고
    • Inhibition of angiogenesis and invasion by 3,3́-diindolylmethane is mediated by the NF-κB downstream target genes MMP-9 and uPA that regulated bioavailability of VEGF in prostate cancer
    • DOI 10.1158/0008-5472.CAN-06-4277
    • Kong D, Li Y, Wang Z, et al. Inhibition of angiogenesis and invasion by 3, 3́-diindolylmethane is mediated by the NF-κ B downstream target genes MMP-9 and u-PA that regulated bioavailability of vascular endothelial growth factor in prostate cancer. Cancer Res 2007; 67: 3310-19. (Pubitemid 46724870)
    • (2007) Cancer Research , vol.67 , Issue.7 , pp. 3310-3319
    • Kong, D.1    Li, Y.2    Wang, Z.3    Banerjee, S.4    Sarkar, F.H.5
  • 51
    • 64649087510 scopus 로고    scopus 로고
    • NF-κB inhibition in human hepa-tocellular carcinoma and its potential as adjunct to sorafenib-based therapy
    • Wu JM, Sheng H, Saxena R, et al. NF-κ B inhibition in human hepa-tocellular carcinoma and its potential as adjunct to sorafenib-based therapy. Cancer Lett 2009; 278: 145-55.
    • (2009) Cancer Lett , vol.278 , pp. 145-155
    • Wu, J.M.1    Sheng, H.2    Saxena, R.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.