Imaging mass spectrometry and genome mining reveal highly antifungal virulence factor of mushroom soft rot pathogen

Angewandte Chemie - International Edition

Volumn 51, Issue 52, 2012, Pages 13173-13177

  Graupner, Katharina ^a   Scherlach, Kirstin ^a   Bretschneider, Tom ^a   Lackner, Gerald ^a   Roth, Martin ^a   Gross, Harald ^b   Hertweck, Christian ^a,c  

^a HANS KNÖLL INSTITUTE   (Germany)

^b UNIVERSITY OF TÜBINGEN   (Germany)

^c FRIEDRICH SCHILLER UNIVERSITY JENA   (Germany)

Author keywords

Biosynthesis; Janthinobacterium agaricidamnosum; Lipopeptides; Natural products; Structure elucidation

Indexed keywords

AGARICUS BISPORUS; ANTI-FUNGAL; ANTIFUNGAL AGENTS; ANTIFUNGALS; BACTERIAL INFECTIONS; BUTTON MUSHROOM; CAUSATIVE AGENTS; COMPLETE DISSOLUTION; DIRECT CONTACT; FUNGAL INFECTION; GENOME MINING; GRAM-NEGATIVE BACTERIA; HUMAN PATHOGENS; IMAGING MASS SPECTROMETRY; JANTHINOBACTERIUM AGARICIDAMNOSUM; LIPOPEPTIDES; LYTIC ENZYMES; NATURAL PRODUCTS; PATHOBIOLOGY; PROTECTIVE MEASURES; SOFT ROT BACTERIUM; SOFT-ROT; STRUCTURE ELUCIDATION; VIRULENCE FACTORS;

BACTERIA; BIOCHEMISTRY; BIOSYNTHESIS; FUNGI; GENES; SECONDARY ION MASS SPECTROMETRY; TISSUE;

PATHOGENS;

ANTIFUNGAL AGENT; CYCLOPEPTIDE; JAGARICIN; NONRIBOSOMAL PEPTIDE SYNTHETASE; PEPTIDE SYNTHASE; POLYKETIDE SYNTHASE;

AGARICALES; ARTICLE; BACTERIAL GENOME; BIOLOGY; CHEMISTRY; CONFORMATION; DRUG EFFECT; FUNGUS; GENETICS; GRAM NEGATIVE BACTERIUM; GROWTH, DEVELOPMENT AND AGING; ISOLATION AND PURIFICATION; MASS SPECTROMETRY; METABOLISM; MICROBIOLOGY; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PLANT ROOT; SYNTHESIS;

AGARICALES; ANTIFUNGAL AGENTS; COMPUTATIONAL BIOLOGY; FUNGI; GENOME, BACTERIAL; GRAM-NEGATIVE BACTERIA; MAGNETIC RESONANCE SPECTROSCOPY; MOLECULAR CONFORMATION; PEPTIDE SYNTHASES; PEPTIDES, CYCLIC; PLANT ROOTS; POLYKETIDE SYNTHASES; SPECTROMETRY, MASS, MATRIX-ASSISTED LASER DESORPTION-IONIZATION;

EID: 84871959363     PISSN: 14337851     EISSN: 15213773     Source Type: Journal    
DOI: 10.1002/anie.201206658     Document Type: Article

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