메뉴 건너뛰기




Volumn 49, Issue 1, 2013, Pages 52-61

Tobacco nitrosamine n-nitrosonornicotine as inhibitor of neuronal nicotinic acetylcholine receptors

Author keywords

N nitrosonornicotine (NNN); Nicotinic acetylcholine receptors

Indexed keywords

NICOTINIC RECEPTOR ALPHA4BETA2; NITROSAMINE; NITROSONORNICOTINE;

EID: 84871951588     PISSN: 08958696     EISSN: 15591166     Source Type: Journal    
DOI: 10.1007/s12031-012-9859-5     Document Type: Article
Times cited : (6)

References (48)
  • 1
    • 63049088086 scopus 로고    scopus 로고
    • Role of non-neuronal nicotinic acetylcholine receptors in angiogenesis
    • 19401144 10.1016/j.biocel.2009.01.013 1:CAS:528:DC%2BD1MXktFertbc%3D
    • Arias HR, Richards VE, Ng D, Ghafoori ME, Le V et al (2009) Role of non-neuronal nicotinic acetylcholine receptors in angiogenesis. Int J Biochem Cell Biol 41:1441-1451
    • (2009) Int J Biochem Cell Biol , vol.41 , pp. 1441-1451
    • Arias, H.R.1    Richards, V.E.2    Ng, D.3    Ghafoori, M.E.4    Le, V.5
  • 2
    • 33646800564 scopus 로고    scopus 로고
    • Nicotinic receptors mediate tumorigenic action of tobacco-derived nitrosamines on immortalized oral epithelial cells
    • 16582591 10.4161/cbt.5.5.2601 1:CAS:528:DC%2BD28Xot1ejsLk%3D
    • Arredondo J, Chernyavsky AI, Grando SA (2006a) Nicotinic receptors mediate tumorigenic action of tobacco-derived nitrosamines on immortalized oral epithelial cells. Cancer Biol Ther 5:511-517
    • (2006) Cancer Biol Ther , vol.5 , pp. 511-517
    • Arredondo, J.1    Chernyavsky, A.I.2    Grando, S.A.3
  • 3
    • 33748184886 scopus 로고    scopus 로고
    • The nicotinic receptor antagonists abolish pathobiologic effects of tobacco-derived nitrosamines on BEP2D cells
    • 16835749 10.1007/s00432-006-0113-9 1:CAS:528:DC%2BD28XoslWmsb0%3D
    • Arredondo J, Chernyavsky AI, Grando SA (2006b) The nicotinic receptor antagonists abolish pathobiologic effects of tobacco-derived nitrosamines on BEP2D cells. J Cancer Res Clin Oncol 132:653-663
    • (2006) J Cancer Res Clin Oncol , vol.132 , pp. 653-663
    • Arredondo, J.1    Chernyavsky, A.I.2    Grando, S.A.3
  • 4
    • 67649133580 scopus 로고    scopus 로고
    • Alpha-conotoxins as pharmacological probes of nicotinic acetylcholine receptors
    • 19448650 10.1038/aps.2009.47 1:CAS:528:DC%2BD1MXmvVSltLY%3D
    • Azam L, McIntosh JM (2009) Alpha-conotoxins as pharmacological probes of nicotinic acetylcholine receptors. Acta Pharmacol Sin 30:771-783
    • (2009) Acta Pharmacol Sin , vol.30 , pp. 771-783
    • Azam, L.1    McIntosh, J.M.2
  • 5
    • 0035902437 scopus 로고    scopus 로고
    • 3 receptor by nicotine, cocaine, and fluoxetine investigated by rapid chemical kinetic techniques
    • 11444989 10.1021/bi0106890 1:CAS:528:DC%2BD3MXksVSjsb8%3D
    • 3 receptor by nicotine, cocaine, and fluoxetine investigated by rapid chemical kinetic techniques. Biochemistry 40:8419-8429
    • (2001) Biochemistry , vol.40 , pp. 8419-8429
    • Breitinger, H.A.1    Geetha, N.2    Hess, G.P.3
  • 6
    • 0018848639 scopus 로고
    • Molecular mechanism of acetylcholine receptor-controlled ion translocation across cell membranes
    • 6928684 10.1073/pnas.77.2.842 1:CAS:528:DyaL3cXhslGru74%3D
    • Cash DJ, Hess GP (1980) Molecular mechanism of acetylcholine receptor-controlled ion translocation across cell membranes. Proc Natl Acad Sci USA 77:842-846
    • (1980) Proc Natl Acad Sci USA , vol.77 , pp. 842-846
    • Cash, D.J.1    Hess, G.P.2
  • 7
    • 79952777760 scopus 로고    scopus 로고
    • Inhibition mechanism of the rat α3β4 nicotinic acetylcholine receptor by the Alzheimer therapeutic tacrine
    • 21247200 10.1021/bi101789y 1:CAS:528:DC%2BC3MXisVyksrk%3D
    • Cheffer A, Ulrich H (2011) Inhibition mechanism of the rat α3β4 nicotinic acetylcholine receptor by the Alzheimer therapeutic tacrine. Biochemistry 50:1763-1770
    • (2011) Biochemistry , vol.50 , pp. 1763-1770
    • Cheffer, A.1    Ulrich, H.2
  • 8
    • 84861968401 scopus 로고    scopus 로고
    • Lipophilicity as a determinant of binding of procaine analogs to rat α3b4 nicotinic acetylcholine receptor
    • doi: 10.1002/jnr.23047
    • Cheffer A, Vieira ME, do Amaral AT, Ulrich H (2012) Lipophilicity as a determinant of binding of procaine analogs to rat α3b4 nicotinic acetylcholine receptor. J Neurosci Res. doi: 10.1002/jnr.23047
    • (2012) J Neurosci Res.
    • Cheffer, A.1    Vieira, M.E.2    Do Amaral, A.T.3    Ulrich, H.4
  • 9
    • 84865747853 scopus 로고    scopus 로고
    • New associations of the genetic polymorphisms in nicotinic receptor genes with the risk of lung cancer
    • doi: 10.1016/j.lfs.2011.12.023
    • Chikova A, Bernard HU, Shchepotin IB, Grando SA (2012) New associations of the genetic polymorphisms in nicotinic receptor genes with the risk of lung cancer. Life Sci. doi: 10.1016/j.lfs.2011.12.023
    • (2012) Life Sci.
    • Chikova, A.1    Bernard, H.U.2    Shchepotin, I.B.3    Grando, S.A.4
  • 10
    • 33645029262 scopus 로고    scopus 로고
    • Nicotine enhances intracellular nicotinic receptor maturation: A novel mechanism of neural plasticity?
    • 16458492 10.1016/j.jphysparis.2005.12.012 1:CAS:528:DC%2BD28XisF2isbo%3D
    • Corringer PJ, Sallette J, Changeux JP (2006) Nicotine enhances intracellular nicotinic receptor maturation: a novel mechanism of neural plasticity? J Physiol Paris 99:162-171
    • (2006) J Physiol Paris , vol.99 , pp. 162-171
    • Corringer, P.J.1    Sallette, J.2    Changeux, J.P.3
  • 11
    • 72649093670 scopus 로고    scopus 로고
    • Smoking, nicotine and neuropsychiatric disorders
    • 19665479 10.1016/j.neubiorev.2009.07.013
    • Dome P, Lazary J, Kalapos MP, Rihmer Z (2009) Smoking, nicotine and neuropsychiatric disorders. Neurosci Biobehav Rev 34:295-342
    • (2009) Neurosci Biobehav Rev , vol.34 , pp. 295-342
    • Dome, P.1    Lazary, J.2    Kalapos, M.P.3    Rihmer, Z.4
  • 12
    • 0035312614 scopus 로고    scopus 로고
    • Tobacco cembranoids block behavioral sensitization to nicotine and inhibit neuronal acetylcholine receptor function
    • 11276047 10.1002/jnr.1049 1:CAS:528:DC%2BD3MXisFWltbk%3D
    • Ferchmin PA, Lucas RJ, Hann RM, Fryer JD, Eaton JB et al (2001) Tobacco cembranoids block behavioral sensitization to nicotine and inhibit neuronal acetylcholine receptor function. J Neurosci Res 64:18-25
    • (2001) J Neurosci Res , vol.64 , pp. 18-25
    • Ferchmin, P.A.1    Lucas, R.J.2    Hann, R.M.3    Fryer, J.D.4    Eaton, J.B.5
  • 13
    • 70350389580 scopus 로고    scopus 로고
    • Actions of octocoral and tobacco cembranoids on nicotinic receptors
    • 19281835 10.1016/j.toxicon.2009.02.033 1:CAS:528:DC%2BD1MXhtlekt7vI
    • Ferchmin PA, Pagán OR, Ulrich H, Szeto AC, Hann RM et al (2009) Actions of octocoral and tobacco cembranoids on nicotinic receptors. Toxicon 54:1174-1182
    • (2009) Toxicon , vol.54 , pp. 1174-1182
    • Ferchmin, P.A.1    Pagán, O.R.2    Ulrich, H.3    Szeto, A.C.4    Hann, R.M.5
  • 14
    • 11844276603 scopus 로고    scopus 로고
    • Neuronal nicotinic receptors: From structure to pathology
    • 15649582 10.1016/j.pneurobio.2004.09.006 1:CAS:528:DC%2BD2MXksVertA%3D%3D
    • Gotti C, Clementi F (2004) Neuronal nicotinic receptors: from structure to pathology. Prog Neurobiol 74:363-396
    • (2004) Prog Neurobiol , vol.74 , pp. 363-396
    • Gotti, C.1    Clementi, F.2
  • 15
    • 68349130498 scopus 로고    scopus 로고
    • Structural and functional diversity of native brain neuronal nicotinic receptors
    • 19481063 10.1016/j.bcp.2009.05.024 1:CAS:528:DC%2BD1MXhtVSmsLjK
    • Gotti C, Clementi F, Fornari A, Gaimarri A, Guiducci S et al (2009) Structural and functional diversity of native brain neuronal nicotinic receptors. Biochem Pharmacol 78:703-711
    • (2009) Biochem Pharmacol , vol.78 , pp. 703-711
    • Gotti, C.1    Clementi, F.2    Fornari, A.3    Gaimarri, A.4    Guiducci, S.5
  • 16
    • 68349133597 scopus 로고    scopus 로고
    • Nicotine-induced upregulation of nicotinic receptors: Underlying mechanisms and relevance to nicotine addiction
    • 19540212 10.1016/j.bcp.2009.06.011 1:CAS:528:DC%2BD1MXhtVSmsLnJ
    • Govind AP, Vezina P, Green WN (2009) Nicotine-induced upregulation of nicotinic receptors: underlying mechanisms and relevance to nicotine addiction. Biochem Pharmacol 78:756-765
    • (2009) Biochem Pharmacol , vol.78 , pp. 756-765
    • Govind, A.P.1    Vezina, P.2    Green, W.N.3
  • 17
    • 0031831381 scopus 로고    scopus 로고
    • Biochemistry, biology, and carcinogenicity of tobacco-specific N-nitrosamines
    • 9625726 10.1021/tx980005y 1:CAS:528:DyaK1cXjvFarsrs%3D
    • Hecht SS (1998) Biochemistry, biology, and carcinogenicity of tobacco-specific N-nitrosamines. Chem Res Toxicol 11:559-603
    • (1998) Chem Res Toxicol , vol.11 , pp. 559-603
    • Hecht, S.S.1
  • 18
    • 0033535375 scopus 로고    scopus 로고
    • DNA adduct formation from tobacco-specific N-nitrosamines
    • 10064856 10.1016/S0027-5107(99)00014-7 1:CAS:528:DyaK1MXhvF2rtLk%3D
    • Hecht SS (1999) DNA adduct formation from tobacco-specific N-nitrosamines. Mutat Res 424:127-142
    • (1999) Mutat Res , vol.424 , pp. 127-142
    • Hecht, S.S.1
  • 19
    • 0023898409 scopus 로고
    • Tobacco-specific nitrosamines, an important group of carcinogens in tobacco and tobacco smoke
    • 3286030 10.1093/carcin/9.6.875 1:CAS:528:DyaL1cXktFyht7o%3D
    • Hecht SS, Hoffmann D (1988) Tobacco-specific nitrosamines, an important group of carcinogens in tobacco and tobacco smoke. Carcinogenesis 9:875-884
    • (1988) Carcinogenesis , vol.9 , pp. 875-884
    • Hecht, S.S.1    Hoffmann, D.2
  • 20
    • 0018096625 scopus 로고
    • Tobacco-specific nitrosamines: Formation by nitrosation of nicotine during curing of tobacco and carcinogenicity in strain A mice
    • 633391 1:CAS:528:DyaE1cXltVWnsrg%3D
    • Hecht SS, Chen CB, Hirota N, Omaf RM, Tso TC et al (1978) Tobacco-specific nitrosamines: formation by nitrosation of nicotine during curing of tobacco and carcinogenicity in strain A mice. J Natl Cancer Inst 60:819-824
    • (1978) J Natl Cancer Inst , vol.60 , pp. 819-824
    • Hecht, S.S.1    Chen, C.B.2    Hirota, N.3    Omaf, R.M.4    Tso, T.C.5
  • 21
    • 0018790793 scopus 로고
    • Fast kinetic studies on the interaction of a fluorescent agonist with the membrane-bound acetylcholine receptor from Torpedo marmorata
    • 436843 10.1111/j.1432-1033.1979.tb12893.x 1:CAS:528:DyaE1MXhvVWlurg%3D
    • Heidmann T, Changeux JP (1979) Fast kinetic studies on the interaction of a fluorescent agonist with the membrane-bound acetylcholine receptor from Torpedo marmorata. Eur J Biochem 94:255-279
    • (1979) Eur J Biochem , vol.94 , pp. 255-279
    • Heidmann, T.1    Changeux, J.P.2
  • 22
    • 0020972770 scopus 로고
    • Acetylcholine receptor-controlled ion translocation: Chemical kinetic investigations of the mechanism
    • 10.1146/annurev.bb.12.060183.002303 1:CAS:528:DyaL3sXksVyqu78%3D
    • Hess GP, Cash DJ, Aoshima H (1983) Acetylcholine receptor-controlled ion translocation: chemical kinetic investigations of the mechanism. Ann Rev Biophys Bioeng 12:443-473
    • (1983) Ann Rev Biophys Bioeng , vol.12 , pp. 443-473
    • Hess, G.P.1    Cash, D.J.2    Aoshima, H.3
  • 23
    • 12944289798 scopus 로고    scopus 로고
    • Mechanism-based discovery of ligands that counteract inhibition of the nicotinic acetylcholine receptor by cocaine and MK-801
    • 11095713 10.1073/pnas.240459497 1:CAS:528:DC%2BD3cXoslynsbo%3D
    • Hess GP, Ulrich H, Breitinger HG, Niu L, Gameiro AM et al (2000) Mechanism-based discovery of ligands that counteract inhibition of the nicotinic acetylcholine receptor by cocaine and MK-801. Proc Natl Acad Sci USA 97:13895-13900
    • (2000) Proc Natl Acad Sci USA , vol.97 , pp. 13895-13900
    • Hess, G.P.1    Ulrich, H.2    Breitinger, H.G.3    Niu, L.4    Gameiro, A.M.5
  • 24
    • 0016290521 scopus 로고
    • N'-Nitrosonornicotine in tobacco
    • 4414773 10.1126/science.186.4160.265 1:CAS:528:DyaE2MXhvFOr
    • Hoffmann D, Hecht SS, Ornaf RM, Wynder EL (1974) N'-Nitrosonornicotine in tobacco. Science 186:265-267
    • (1974) Science , vol.186 , pp. 265-267
    • Hoffmann, D.1    Hecht, S.S.2    Ornaf, R.M.3    Wynder, E.L.4
  • 25
    • 22844432580 scopus 로고    scopus 로고
    • Neuronal nicotinic acetylcholine receptors: Structural revelations, target identifications, and therapeutic inspirations
    • 16033252 10.1021/jm040219e 1:CAS:528:DC%2BD2MXmtlSgt78%3D
    • Jensen AA, Frolund B, Liljefors T, Krogsgaard-Larsen T (2005) Neuronal nicotinic acetylcholine receptors: structural revelations, target identifications, and therapeutic inspirations. J Med Chem 48:4705-4745
    • (2005) J Med Chem , vol.48 , pp. 4705-4745
    • Jensen, A.A.1    Frolund, B.2    Liljefors, T.3    Krogsgaard-Larsen, T.4
  • 26
    • 84965075853 scopus 로고
    • A study of the desensitization produced by acetylcholine at the motor end-plate
    • 13463799 1:STN:280:DyaG1c%2Fgs1Cmug%3D%3D
    • Katz B, Thesleff S (1957) A study of the desensitization produced by acetylcholine at the motor end-plate. J Physiol 138:63-80
    • (1957) J Physiol , vol.138 , pp. 63-80
    • Katz, B.1    Thesleff, S.2
  • 27
    • 0347093473 scopus 로고    scopus 로고
    • Mechanism-based approach to the successful prevention of cocaine inhibition of the neuronal (α3β4) nicotinic acetylcholine receptor
    • 14717603 10.1021/bi034838l 1:CAS:528:DC%2BD3sXpvVKhurg%3D
    • Krivoshein AV, Hess GP (2004) Mechanism-based approach to the successful prevention of cocaine inhibition of the neuronal (α3β4) nicotinic acetylcholine receptor. Biochemistry 43:481-489
    • (2004) Biochemistry , vol.43 , pp. 481-489
    • Krivoshein, A.V.1    Hess, G.P.2
  • 28
    • 2442502651 scopus 로고    scopus 로고
    • Maternal smoking and the risk of orofacial clefts: Susceptibility with NAT1 and NAT2 polymorphisms
    • 15127906 10.1097/01.ede.0000112214.33432.cc
    • Lammer EJ, Shaw GM, Iovannisci DM, Van Waes J, Finnell RH (2004) Maternal smoking and the risk of orofacial clefts: susceptibility with NAT1 and NAT2 polymorphisms. Epidemiology 15:150-156
    • (2004) Epidemiology , vol.15 , pp. 150-156
    • Lammer, E.J.1    Shaw, G.M.2    Iovannisci, D.M.3    Van Waes, J.4    Finnell, R.H.5
  • 29
    • 33845413410 scopus 로고    scopus 로고
    • Sequential interplay of nicotinic and GABAergic signaling guides neuronal development
    • 17158331 10.1126/science.1134246 1:CAS:528:DC%2BD28Xht1OntL%2FO
    • Liu Z, Neff RA, Berq DK (2006) Sequential interplay of nicotinic and GABAergic signaling guides neuronal development. Science 314:1610-1613
    • (2006) Science , vol.314 , pp. 1610-1613
    • Liu, Z.1    Neff, R.A.2    Berq, D.K.3
  • 30
    • 8844232736 scopus 로고    scopus 로고
    • On-line screening of conformationally constrained nicotines and anabasines for agonist activity at the alpha3beta4- and alpha4beta2-nicotinic acetylcholine receptors using immobilized receptor-based liquid chromatographic stationary phases
    • 15556538 10.1016/j.jchromb.2004.09.042 1:CAS:528:DC%2BD2cXhtVSnsL7K
    • Moaddel R, Jozwiak K, Yamaguchi R, Cobello C, Whittington K et al (2004) On-line screening of conformationally constrained nicotines and anabasines for agonist activity at the alpha3beta4- and alpha4beta2-nicotinic acetylcholine receptors using immobilized receptor-based liquid chromatographic stationary phases. J Chromatogr B Analyt Technol Biomed Life Sci 813:235-240
    • (2004) J Chromatogr B Analyt Technol Biomed Life Sci , vol.813 , pp. 235-240
    • Moaddel, R.1    Jozwiak, K.2    Yamaguchi, R.3    Cobello, C.4    Whittington, K.5
  • 31
    • 52249091997 scopus 로고    scopus 로고
    • A novel physiological property of snake bradykinin-potentiating peptides - Reversion of MK-801 inhibition of nicotinic acetylcholine receptors
    • 18598727 10.1016/j.peptides.2008.06.002 1:CAS:528:DC%2BD1cXhtFCkur3F
    • Nery AA, Trujillo CA, Lameu C, Konno K, Oliveira V et al (2008) A novel physiological property of snake bradykinin-potentiating peptides - reversion of MK-801 inhibition of nicotinic acetylcholine receptors. Peptides 29:1708-1715
    • (2008) Peptides , vol.29 , pp. 1708-1715
    • Nery, A.A.1    Trujillo, C.A.2    Lameu, C.3    Konno, K.4    Oliveira, V.5
  • 32
    • 77954538960 scopus 로고    scopus 로고
    • Alpha7 nicotinic acetylcholine receptor expression and activity during neuronal differentiation of PC12 pheochromocytoma cells
    • 20461497 10.1007/s12031-010-9369-2 1:CAS:528:DC%2BC3cXmslShsbY%3D
    • Nery AA, Resende RR, Martins AH, Trujillo CA, Eterovic VA et al (2010) Alpha7 nicotinic acetylcholine receptor expression and activity during neuronal differentiation of PC12 pheochromocytoma cells. J Mol Neurosci 41:329-339
    • (2010) J Mol Neurosci , vol.41 , pp. 329-339
    • Nery, A.A.1    Resende, R.R.2    Martins, A.H.3    Trujillo, C.A.4    Eterovic, V.A.5
  • 33
    • 0027212222 scopus 로고
    • An acetylcholine receptor regulatory site in BC3H1 cells: Characterized by laser-pulse photolysis in the microsecond-to-millisecond time region
    • 8471597 10.1021/bi00066a001 1:CAS:528:DyaK3sXhvVCjt7s%3D
    • Niu L, Hess GP (1993) An acetylcholine receptor regulatory site in BC3H1 cells: characterized by laser-pulse photolysis in the microsecond-to-millisecond time region. Biochemistry 32:3831-3835
    • (1993) Biochemistry , vol.32 , pp. 3831-3835
    • Niu, L.1    Hess, G.P.2
  • 34
    • 67449149484 scopus 로고    scopus 로고
    • A cembranoid from tobacco prevents the expression of nicotine-induced withdrawal behavior in planarian worms
    • 19490913 10.1016/j.ejphar.2009.05.022
    • Pagán OR, Rowlands AL, Fattore AL, Coudron T, Urban KR et al (2009) A cembranoid from tobacco prevents the expression of nicotine-induced withdrawal behavior in planarian worms. Eur J Pharmacol 615:118-124
    • (2009) Eur J Pharmacol , vol.615 , pp. 118-124
    • Pagán, O.R.1    Rowlands, A.L.2    Fattore, A.L.3    Coudron, T.4    Urban, K.R.5
  • 35
    • 40949096392 scopus 로고    scopus 로고
    • Role of acetylcholine receptors in proliferation and differentiation of P19 embryonal carcinoma cells
    • 18331729 10.1016/j.yexcr.2008.01.003 1:CAS:528:DC%2BD1cXktFCjuro%3D
    • Resende RR, Alves AS, Britto LR, Ulrich H (2008) Role of acetylcholine receptors in proliferation and differentiation of P19 embryonal carcinoma cells. Exp Cell Res 314:1429-1443
    • (2008) Exp Cell Res , vol.314 , pp. 1429-1443
    • Resende, R.R.1    Alves, A.S.2    Britto, L.R.3    Ulrich, H.4
  • 36
    • 0000802778 scopus 로고
    • Macrocyclic diterpenes. α- And β-4,8,13-duvatriene-1,3-diols from tobacco
    • 10.1021/jo01058a056 1:CAS:528:DyaF3sXjsVSm
    • Roberts DL, Rowland RL (1962) Macrocyclic diterpenes. α- and β-4,8,13-duvatriene-1,3-diols from tobacco. J Org Chem 27:3989-3995
    • (1962) J Org Chem , vol.27 , pp. 3989-3995
    • Roberts, D.L.1    Rowland, R.L.2
  • 37
    • 12344296676 scopus 로고    scopus 로고
    • Effect of N'-nitrosonornicotine (NNN) on murine palatal fusion in vitro
    • 15664274 10.1016/j.tox.2004.10.015 1:CAS:528:DC%2BD2MXms1OjsA%3D%3D
    • Saito T, Cui XM, Yamamoto T, Shiomi N, Bringas PJ et al (2005) Effect of N'-nitrosonornicotine (NNN) on murine palatal fusion in vitro. Toxicology 207:475-485
    • (2005) Toxicology , vol.207 , pp. 475-485
    • Saito, T.1    Cui, X.M.2    Yamamoto, T.3    Shiomi, N.4    Bringas, P.J.5
  • 38
    • 34249284421 scopus 로고    scopus 로고
    • Nitrosamines as nicotinic receptor ligands
    • 17459420 10.1016/j.lfs.2007.03.006 1:CAS:528:DC%2BD2sXmtVeht70%3D
    • Schuller HM (2007) Nitrosamines as nicotinic receptor ligands. Life Sci 80:2274-2280
    • (2007) Life Sci , vol.80 , pp. 2274-2280
    • Schuller, H.M.1
  • 39
    • 0032499397 scopus 로고    scopus 로고
    • Tobacco-specific carcinogenic nitrosamines. Ligands for nicotinic acetylcholine receptors in human lung cancer cells
    • 10076528 10.1016/S0006-2952(97)00651-5 1:CAS:528:DyaK1cXislemsb4%3D
    • Schuller HM, Orloff M (1998) Tobacco-specific carcinogenic nitrosamines. Ligands for nicotinic acetylcholine receptors in human lung cancer cells. Biochem Pharmacol 55:1377-1384
    • (1998) Biochem Pharmacol , vol.55 , pp. 1377-1384
    • Schuller, H.M.1    Orloff, M.2
  • 41
    • 26844498333 scopus 로고    scopus 로고
    • Conversion of nicotine to nornicotine in Nicotiana tabacum is mediated by CYP82E4, a cytochrome P450 monooxygenase
    • 16192354 10.1073/pnas.0506581102 1:CAS:528:DC%2BD2MXhtFKjsbrI
    • Siminszky B, Gavilano L, Bowen SW, Dewey RE (2005) Conversion of nicotine to nornicotine in Nicotiana tabacum is mediated by CYP82E4, a cytochrome P450 monooxygenase. Proc Natl Acad Sci USA 102:14919-14924
    • (2005) Proc Natl Acad Sci USA , vol.102 , pp. 14919-14924
    • Siminszky, B.1    Gavilano, L.2    Bowen, S.W.3    Dewey, R.E.4
  • 42
    • 0021150988 scopus 로고
    • Agonists block currents through acetylcholine receptor channels
    • 6478036 10.1016/S0006-3495(84)84022-9 1:CAS:528:DyaL2cXltVCrs70%3D
    • Sine SM, Steinbach JH (1984) Agonists block currents through acetylcholine receptor channels. Biophys J 46:277-283
    • (1984) Biophys J , vol.46 , pp. 277-283
    • Sine, S.M.1    Steinbach, J.H.2
  • 43
    • 0018389601 scopus 로고
    • Functional consequences of agonist-mediated state transitions in the cholinergic receptor - Studies in cultured muscle cells
    • 429353 1:CAS:528:DyaE1MXktFelsrY%3D
    • Sine S, Taylor P (1979) Functional consequences of agonist-mediated state transitions in the cholinergic receptor - studies in cultured muscle cells. J Biol Chem 254:3315-3325
    • (1979) J Biol Chem , vol.254 , pp. 3315-3325
    • Sine, S.1    Taylor, P.2
  • 45
    • 0023516913 scopus 로고
    • Chemical kinetic measurements of a mammalian acetylcholine receptor by a fast-reaction technique
    • 2447583 10.1073/pnas.84.24.8758 1:CAS:528:DyaL1cXht1Cmu7g%3D
    • Udgaonkar JB, Hess GP (1987) Chemical kinetic measurements of a mammalian acetylcholine receptor by a fast-reaction technique. Proc Natl Acad Sci USA 84:8758-8762
    • (1987) Proc Natl Acad Sci USA , vol.84 , pp. 8758-8762
    • Udgaonkar, J.B.1    Hess, G.P.2
  • 46
    • 38049046785 scopus 로고    scopus 로고
    • Mode of cembranoid action on embryonic muscle acetylcholine receptor
    • 17868151 10.1002/jnr.21468 1:CAS:528:DC%2BD1cXnsV2jug%3D%3D
    • Ulrich H, Akk G, Nery AA, Trujillo CA, Rodriguez AD et al (2008) Mode of cembranoid action on embryonic muscle acetylcholine receptor. J Neurosci Res 86:93-107
    • (2008) J Neurosci Res , vol.86 , pp. 93-107
    • Ulrich, H.1    Akk, G.2    Nery, A.A.3    Trujillo, C.A.4    Rodriguez, A.D.5
  • 47
    • 84871958852 scopus 로고    scopus 로고
    • World Health Organization Accessed 29 Feb 2012
    • World Health Organization (2012) Tobacco key facts. Available at: http://www.who.int/mediacentre/factsheets/fs339/en/index.html. Accessed 29 Feb 2012
    • (2012) Tobacco Key Facts
  • 48
    • 0031595642 scopus 로고    scopus 로고
    • Rat α3β4 subtype of neuronal nicotinic acetylcholine receptor stably expressed in a transfected cell line: Pharmacology of ligand binding and function
    • 1:CAS:528:DyaK1cXlsVWls78%3D
    • Xiao Y, Meyer EL, Thompson JM, Surin A, Wroblewski J et al (1998) Rat α3β4 subtype of neuronal nicotinic acetylcholine receptor stably expressed in a transfected cell line: pharmacology of ligand binding and function. Mol Pharmacol 54:322-333
    • (1998) Mol Pharm , vol.54 , pp. 322-333
    • Xiao, Y.1    Meyer, E.L.2    Thompson, J.M.3    Surin, A.4    Wroblewski, J.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.