In vitro expressed GPCR inserted in polymersome membranes for ligand-binding studies

Angewandte Chemie - International Edition

Volumn 52, Issue 2, 2013, Pages 749-753

  May, Sylvia ^a   Andreasson Ochsner, Mirjam ^a   Fu, Zhikang ^a   Low, Ying Xiu ^a   Tan, Darren ^a   De Hoog, Hans Peter M ^b   Ritz, Sandra ^c   Nallani, Madhavan ^a   Sinner, Eva Kathrin ^d  

^a INSTITUTE OF MATERIALS RESEARCH AND ENGINEERING   (Singapore)

^b NANYANG TECHNOLOGICAL UNIVERSITY   (Singapore)

^c MAX PLANCK INSTITUTE FOR POLYMER RESEARCH   (Germany)

^d UNIVERSITY OF NATURAL RESOURCES AND LIFE SCIENCES   (Austria)

Author keywords

biosensors; drug discovery; polymers; protein expression; receptors

Indexed keywords

BLOCK COPOLYMER VESICLES; CONFORMATIONAL INTEGRITY; DRUG DISCOVERY; DRUG SCREENING; G-PROTEIN COUPLED RECEPTORS; IN-VITRO; LIGAND BINDING; POLYMERSOMES; PROTEIN EXPRESSIONS; RECEPTORS;

AMINES; BIOSENSORS; BLOCK COPOLYMERS; LIGANDS; NEUROPHYSIOLOGY;

POLYMERS;

G PROTEIN COUPLED RECEPTOR; LIGAND; POLYMER;

ARTICLE; CHEMISTRY; DRUG DEVELOPMENT; HUMAN; METABOLISM;

DRUG DISCOVERY; HUMANS; LIGANDS; POLYMERS; RECEPTORS, G-PROTEIN-COUPLED;

EID: 84871940677     PISSN: 14337851     EISSN: 15213773     Source Type: Journal    
DOI: 10.1002/anie.201204645     Document Type: Article

References (26)

1. E. Jacoby, R. Bouhelal, M. Gerspacher, K. Seuwen, ChemMedChem 2006, 1, 760.
2. M. A. Yildirim, K. I. Goh, M. E. Cusick, A. L. Barabasi, M. Vidal, Nat. Biotechnol. 2007, 25, 1119.
3. X.-L. Tang, Y. Wang, D. L. Li, J. Luo, M. Y. Lui, Acta Pharmacol. Sin. 2012, 33, 363.
4. Y. Hong, B. L. Webb, H. Su, E. J. Mozdy, Y. Fang, Q. Wu, L. Liu, J. Beck, A. M. Ferrie, S. Raghavan, J. Mauro, A. Carre, D. Mueller, F. Lai, B. Rasnow, M. Johnson, H. Min, J. Salon, J. Lahiri, J. Am. Chem. Soc. 2005, 127, 15350.
5. C. Danelon, S. Terrettaz, O. Guenat, M. Koudelka, H. Vogel, Methods 2008, 46, 104.
6. K. Bailey, M. Bally, W. Leifert, J. Voros, T. McMurchie, Proteomics 2009, 9, 2052.
7. F. Degorce, A. Card, S. Soh, E. Trinquet, G. P. Knapik, B. Xie, Curr. Chem. Genomics 2009, 3, 22.
8. R. Heilker, M. Wolff, C. S. Tautermann, M. Bieler, Drug Discovery Today 2009, 14, 231.
9. M. Bally, K. Bailey, K. Sugihara, D. Grieshaber, J. Voros, B. Stadler, Small 2010, 6, 2481.
10. F. Katzen, T. C. Peterson, W. Kudlicki, Trends Biotechnol. 2009, 27, 455.
11. A. González-Pérez, K. B. Stibius, T. Vissing, C. H. Nielsen, O. G. Mouritsen, Langmuir 2009, 25, 10447.
12. Z. Z. F. Meng, J. Phys. Chem. Lett. 2011, 2, 1533.
13. A. González-Pérez, V. Castelletto, I. W. Hamley, P. Taboada, Soft Matter 2011, 7, 1129.
14. D. Hua, L. Kuang, H. Liang, J. Am. Chem. Soc. 2011, 133, 2354.
15. M. Nallani, M. Andreasson-Ochsner, C. W. Tan, E. K. Sinner, Y. Wisantoso, S. Geifman-Shochat, W. Hunziker, Biointerphases 2011, 6, 153.
16. M. Andreasson-Ochsner, Z. Fu, S. May, L. Y. Xiu, M. Nallani, E. K. Sinner, Langmuir 2012, 28, 2044.
17. A. Rath, M. Glibowicka, V. G. Nadeau, G. Chen, C. M. Deber, Proc. Natl. Acad. Sci. USA 2009, 106, 1760.
18. C. Missale, S. R. Nash, S. W. Robinson, M. Jaber, M. G. Caron, Physiol. Rev. 1998, 78, 189.
19. J. A. Gingrich, M. G. Caron, Annu. Rev. Neurosci. 1993, 16, 299
20. H.-P. M. de Hoog, M. Nallani, B. Liedberg, Polym. Chem. 2012, 3, 302.
21. C. Nardin, J. Widmer, M. Winterhalter, W. Meier, Eur. Phys. J. E 2001, 4, 403.
22. H. J. Choi, C. D. Montemagno, Nano Lett. 2005, 5, 2538.
23. C. Hyo-Jick, L. Hyeseung, D. M. Carlo, Nanotechnology 2005, 16, 1589.
24. M. Kumar, M. Grzelakowski, J. Zilles, M. Clark, W. Meier, Proc. Natl. Acad. Sci. USA 2007, 104, 20719.
25. G. Srinivas, D. E. Discher, M. L. Klein, Nano Lett. 2005, 5, 2343.
26. H. Bermudez, A. K. Brannan, D. A. Hammer, F. S. Bates, D. E. Discher, Macromolecules 2002, 35, 8203.