Protective effect of planarian DJ-1 against 6-hydroxydopamine-induced neurotoxicity

Neuroscience Research

Volumn 74, Issue 3-4, 2012, Pages 277-283

  Tsushima, Jun ^a   Nishimura, Kaneyasu ^a,b,e   Tashiro, Natsuka ^a   Takata, Kazuyuki ^a   Ashihara, Eishi ^a   Yoshimoto, Kanji ^c   Ariga, Hiroyoshi ^d   Agata, Kiyokazu ^b   Kitamura, Yoshihisa ^a  

^a KYOTO PHARMACEUTICAL UNIVERSITY   (Japan)

^b KYOTO UNIVERSITY   (Japan)

^c KYOTO PREFECTURAL UNIVERSITY OF MEDICINE   (Japan)

^d HOKKAIDO UNIVERSITY   (Japan)

^e KYOTO UNIVERSITY   (Japan)

Author keywords

6 Hydroxydopamine induced neurotoxicity; DJ 1; Oxidative stress; Planarians

Indexed keywords

ANTIOXIDANT; MESSENGER RNA; OXIDOPAMINE; REACTIVE OXYGEN METABOLITE;

ANIMAL EXPERIMENT; ARTICLE; CANCER CELL CULTURE; CENTRAL NERVOUS SYSTEM; DOPAMINERGIC NERVE CELL; GENE EXPRESSION; GENE FUNCTION; GENE ISOLATION; HUMAN; HUMAN CELL; IN SITU HYBRIDIZATION; NEUROPROTECTION; NEUROTOXICITY; NONHUMAN; ONCOGENE; PHARYNX; PRIORITY JOURNAL; RNA INTERFERENCE; STEM CELL;

ADRENERGIC AGENTS; AMINO ACID SEQUENCE; ANIMALS; BLOTTING, WESTERN; CELL LINE, TUMOR; DOPAMINERGIC NEURONS; FLUORESCENT ANTIBODY TECHNIQUE; HUMANS; IN SITU HYBRIDIZATION; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MOLECULAR SEQUENCE DATA; NEUROBLASTOMA; ONCOGENE PROTEINS; OXIDOPAMINE; PLANARIANS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SEQUENCE HOMOLOGY, AMINO ACID;

EID: 84871932847     PISSN: 01680102     EISSN: 18728111     Source Type: Journal    
DOI: 10.1016/j.neures.2012.09.003     Document Type: Article

References (47)

1. Agata K., Soejima Y., Kato K., Kobayashi C., Umesono Y., Watanabe K. Structure of the planarian central nervous system (CNS) revealed by neuronal cell markers. Zoolog. Sci. 1998, 15:433-440.
2. Agata K., Watanabe K. Molecular and cellular aspects of planarian regeneration. Semin. Cell Dev. Biol. 1999, 10:377-383.
3. Agata K., Umesono Y. Brain regeneration from pluripotent stem cells in planarian. Philos. Trans. R. Soc. Lond. B: Biol. Sci. 2008, 363:2071-2078.
4. Bonifati V., Rizzu P., van Baren M.J., Schaap O., Breedveld G.J., Krieger E., Dekker M.C., Squitieri F., Ibanez P., Joosse M., van Dongen J.W., Vanacore N., van Swieten J.C., Brice A., Meco G., van Duijn C.M., Oostra B.A., Heutink P. Mutations in the DJ-1 gene associated with autosomal recessive early-onset parkinsonism. Science 2003, 299:256-259.
5. Canet-Aviles R.M., Wilson M.A., Miller D.W., Ahmad R., McLendon C., Bandyopadhyay S., Baptista M.J., Ringe D., Petsko G.A., Cookson M.R. The Parkinson's disease protein DJ-1 is neuroprotective due to cysteine-sulfinic acid-driven mitochondrial localization. Proc. Natl. Acad. Sci. U.S.A. 2004, 101:9103-9108.
6. Cebrià F., Kudome T., Nakazawa M., Mineta K., Ikeo K., Gojobori T., Agata K. The expression of neural-specific genes reveals the structural and molecular complexity of the planarian central nervous system. Mech. Dev. 2002, 116:199-204.
7. Eisenhoffer G.T., Kang H., Sánchez Alvarado A. Molecular analysis of stem cells and their descendants during cell turnover and regeneration in the planarian Schmidtea mediterranea. Cell Stem Cell 2008, 3:327-339.
8. Gasser T. Mendelian forms of Parkinson's disease. Biochim. Biophys. Acta 2009, 7:587-596.
9. Gorner K., Holtorf E., Odoy S., Nuscher B., Yamamoto A., Regula J.T., Beyer K., Haass C., Kahle P.J. Differential effects of Parkinson's disease-associated mutations on stability and folding of DJ-1. J. Biol. Chem. 2004, 279:5691-6943.
10. Hayashi T., Asami M., Higuchi S., Shibata N., Agata K. Isolation of planarian X-ray-sensitive stem cells by fluorescence-activated cell sorting. Dev. Growth Differ. 2006, 48:371-380.
11. Honbou K., Suzuki N.N., Horiuchi M., Niki T., Taira T., Ariga H., Inagaki F. The crystal structure of DJ-1, a protein related to male fertility and Parkinson's disease. J. Biol. Chem. 2003, 278:31380-31384.
12. Inden M., Taira T., Kitamura Y., Yanagida T., Tsuchiya D., Takata K., Yanagisawa D., Nishimura K., Taniguchi T., Kiso Y., Yoshimoto K., Agatsuma T., Koide-Yoshida S., Iguchi-Ariga S.M., Shimohama S., Ariga H. PARK7 DJ-1 protects against degeneration of nigral dopaminergic neurons in Parkinson's disease rat model. Neurobiol. Dis. 2006, 24:144-158.
13. Kinumi T., Kimata J., Taira T., Ariga H., Niki E. Cysteine-106 of DJ-1 is the most sensitive cysteine residue to hydrogen peroxide mediated oxidation in vivo in human umbilical vein endothelial cells. Biochem. Biophys. Res. Commun. 2004, 317:722-728.
14. Kitamura Y., Kosaka T., Kakimura J., Matsuoka Y., Kohno Y., Nomura Y., Taniguchi T. Protective effects of the antiparkinsonian drugs talipexole and pramipexole against 1-methyl-4-phenylpyridiniuminduced apoptotic death in human neuroblastoma SH-SY5Y cells. Mol. Pharmacol. 1998, 54:1046-1054.
15. Lang A.E., Lozano A.M. Parkinson's disease. First of two parts. N. Engl. J. Med. 1998, 339:1044-1053.
16. Lang A.E., Lozano A.M. Parkinson's disease. Second of two parts. N. Engl. J. Med. 1998, 339:1130-1143.
17. Lees A.J., Hardy J., Revesz T. Parkinson's disease. Lancet 2009, 373:2055-2066.
18. Miller D.W., Ahmad R., Hague S., Baptista M.J., Canet-Aviles R., McLendon C., Carter D.M., Zhu P.P., Stadler J., Chandran J., Klinefelter G.R., Blackstone C., Cookson M.R. L166P mutant DJ-1, causative for recessive Parkinson's disease, is degraded through the ubiquitin-proteasome system. J. Biol. Chem. 2003, 278:36588-36595.
19. Mineta K., Nakazawa M., Cebria F., Ikeo K., Agata K., Gojobori T. Origin and evolutionary process of the CNS elucidated by comparative genomics analysis of planarian ESTs. Proc. Natl. Acad. Sci. U.S.A. 2003, 100:7666-7671.
20. Moore D.J., Zhang L., Dawson T.M., Dawson V.L. A missense mutation (L166P) in DJ-1, linked to familial Parkinson's disease, confers reduced protein stability and impairs homo-oligomerization. J. Neurochem. 2003, 87:1558-1567.
21. Moore D.J., West A.B., Dawson V.L., Dawson T.M. Molecular pathophysiology of Parkinson's disease. Annu. Rev. Neurosci. 2005, 28:57-87.
22. Nagakubo D., Taira T., Kitaura H., Ikeda M., Tamai K., Iguchi-Ariga S.M., Ariga H. DJ-1, a novel oncogene which transforms mouse NIH3T3 cells in cooperation with ras. Biochem. Biophys. Res. Commun. 1997, 231:509-513.
23. Nakazawa M., Cebrià F., Mineta K., Ikeo K., Agata K., Gojobori T. Search for the evolutionary origin of a brain: planarian brain characterized by microarray. Mol. Biol. Evol. 2003, 20:784-791.
24. Niki T., Takahashi-Niki K., Taira T., Iguchi-Ariga S.M., Ariga H. DJBP: a novel DJ-1-binding protein, negatively regulates the androgen receptor by recruiting histone deacetylase complex, and DJ-1 antagonizes this inhibition by abrogation of this complex. Mol. Cancer Res. 2003, 1:247-261.
25. Nishimura K., Kitamura Y., Inoue T., Umesono Y., Sano S., Yoshimoto K., Inden M., Takata K., Taniguchi T., Shimohama S., Agata K. Reconstruction of dopaminergic neural network and locomotion function in planarian regenerates. Dev. Neurobiol. 2007, 67:1059-1078.
26. Nishimura K., Kitamura Y., Inoue T., Umesono Y., Yoshimoto K., Takeuchi K., Taniguchi T., Agata K. Identification and distribution of tryptophan hydroxylase (TPH)-positive neurons in the planarian Dugesia japonica. Neurosci. Res. 2007, 59:101-106.
27. Nishimura K., Kitamura Y., Umesono Y., Takeuchi K., Takata K., Taniguchi T., Agata K. Identification of glutamic acid decarboxylase gene and distribution of GABAergic nervous system in the planarian Dugesia japonica. Neuroscience 2008, 153:1103-1114.
28. Nishimura K., Kitamura Y., Inoue T., Umesono Y., Taniguchi T., Agata K. Characterization of tyramine β-hydroxylase in planarian Dugesia japonica: cloning and expression. Neurochem. Int. 2008, 53:184-192.
29. Nishimura K., Kitamura Y., Taniguchi T., Agata K. Analysis of motor function modulated by cholinergic neurons in planarian Dugesia japonica. Neuroscience 2010, 168:18-30.
30. Nishimura K., Inoue T., Yoshimoto K., Taniguchi T., Kitamura Y., Agata K. Regeneration of dopaminergic neurons after 6-hydroxydopamine-induced lesion in planarian brain. J. Neurochem. 2011, 119:1217-1231.
31. Olzmann J.A., Brown K., Wilkinson K.D., Rees H.D., Huai Q., Ke H., Levey A.I., Li L., Chin L.S. Familial Parkinson's disease associated L166P mutation disrupts DJ-1 protein folding and function. J. Biol. Chem. 2004, 279:8506-8515.
32. Orii H., Sakurai T., Watanabe K. Distribution of the stem cells (neoblasts) in the planarian Dugesia japonica. Dev. Genes Evol. 2005, 215:143-157.
33. Reddien P.W., Sanchez Alvarado A. Fundamentals of planarian regeneration. Annu. Rev. Cell Dev. Biol. 2004, 20:725-757.
34. Sánchez Alvarado A., Newmark P.A. Double-stranded RNA specifically disrupts gene expression during planarian regeneration. Proc. Natl. Acad. Sci. U.S.A. 1999, 96:5049-5054.
35. Shendelman S., Jonason A., Martinat C., Leete T., Abeliovich A. DJ-1 is a redox-dependent molecular chaperone that inhibits alpha-synuclein aggregate formation. PLoS Biol. 2004, 2:e362.
36. Shibata N., Rouhana L., Agata K. Cellular and molecular dissection of pluripotent adult somatic stem cells in planarians. Dev. Growth Differ. 2010, 52:27-41.
37. Shinbo Y., Taira T., Niki T., Iguchi-Ariga S.M., Ariga H. DJ-1 restores p53 transcription activity inhibited by Topors/p53BP3. Int. J. Oncol. 2005, 26:641-648.
38. Shinbo Y., Niki T., Taira T., Ooe H., Takahashi-Niki K., Maita C., Seino C., Iguchi-Ariga S.M., Ariga H. Proper SUMO-1 conjugation is essential to DJ-1 to exert its full activities. Cell Death Differ. 2006, 13:96-108.
39. Taira T., Saito Y., Niki T., Iguchi-Ariga S.M., Takahashi K., Ariga H. DJ-1 has a role in antioxidative stress to prevent cell death. EMBO Rep. 2004, 5:213-218.
40. Takahashi K., Taira T., Niki T., Seino C., Iguchi-Ariga S.M., Ariga H. DJ-1 positively regulates the androgen receptor by impairing the binding of PIASx alpha to the receptor. J. Biol. Chem. 2001, 276:37556-37563.
41. Takahashi-Niki K., Niki T., Taira T., Iguchi-Ariga S.M., Ariga H. Reduced anti-oxidative stress activities of DJ-1 mutants found in Parkinson's disease patients. Biochem. Biophys. Res. Commun. 2004, 320:389-397.
42. Takano T., Pulvers J.N., Inoue T., Tarui H., Sakamoto H., Agata K., Umesono Y. Regeneration-dependent conditional gene knockdown (Readyknock) in planarian: demonstration of requirement for Djsnap-25 expression in the brain for negative phototactic behavior. Dev. Growth Differ. 2007, 49:383-394.
43. Tazaki A., Gaudieri S., Ikeo K., Gojobori T., Watanabe K., Agata K. Neural network in planarian revealed by an antibody against planarian synaptotagmin homologue. Biochem. Biophys. Res. Commun. 1999, 260:426-432.
44. Watanabe K., Sakai F., Orii H. Stepwise dilution screening of a cDNA library by polymerase chain reaction. Anal. Biochem. 1997, 252:213-214.
45. Yanagida T., Tsushima J., Kitamura Y., Yanagisawa D., Takata K., Shibaike T., Yamamoto A., Taniguchi T., Yasui H., Taira T., Morikawa S., Inubushi T., Tooyama I., Ariga H. Oxidative stress induction of DJ-1 protein in reactive astrocytes scavenges free radicals and reduces cell injury. Oxid. Med. Cell. Longev. 2009, 2:36-42.
46. Yanagisawa D., Kitamura Y., Inden M., Takata K., Taniguchi T., Morikawa S., Morita M., Inubushi T., Tooyama I., Taira T., Iguchi-Ariga S.M., Akaike A., Ariga H. DJ-1 protects against neurodegeneration caused by focal cerebral ischemia and reperfusion in rats. J. Cereb. Blood Flow Metab. 2008, 28:563-578.
47. Zhou W., Zhu M., Wilson M.A., Petsko G.A., Fink A.L. The oxidation state of DJ-1 regulates its chaperone activity toward alpha-synuclein. J. Mol. Biol. 2006, 356:1036-1048.