Does treatment with bone marrow mononuclear cells recover skilled motor function after focal cortical ischemia? Analysis with a forelimb skilled motor task in rats

Brain Research

Volumn 1492, Issue , 2013, Pages 130-139

  De Fátima Dos Santos Sampaio, Maria ^a   Marcilio, Fralini Dos Santos ^a   Giraldi Guimarães, Arthur ^a  

^a UNIVERSIDADE ESTADUAL DO NORTE FLUMINENSE DARCY RIBEIRO   (Brazil)

Author keywords

Cell therapy; Cerebral cortex; Dexterity; Sensorimotor function; Stroke

Indexed keywords

SODIUM CHLORIDE;

ANIMAL EXPERIMENT; ARTICLE; BONE MARROW MONONUCLEAR CELL; BRAIN ISCHEMIA; CELL THERAPY; CONTROLLED STUDY; CONVALESCENCE; DRUG PELLET; EVOKED SOMATOSENSORY RESPONSE; FORELIMB; MALE; MONONUCLEAR CELL; MOTOR PERFORMANCE; NONHUMAN; PRIORITY JOURNAL; RAT; SENSORIMOTOR FUNCTION; THERMOCOAGULATION;

ANIMALS; BONE MARROW TRANSPLANTATION; BRAIN ISCHEMIA; DISEASE MODELS, ANIMAL; FORELIMB; LEUKOCYTES, MONONUCLEAR; MALE; MOTOR SKILLS; RATS; RATS, WISTAR; RECOVERY OF FUNCTION;

ANIMALIA; RATTUS; RATTUS NORVEGICUS;

EID: 84871921915     PISSN: 00068993     EISSN: 18726240     Source Type: Journal    
DOI: 10.1016/j.brainres.2012.11.026     Document Type: Article

References (42)

1. M. Alaverdashvili, and I.Q. Whishaw Compensation aids skilled reaching in aging and in recovery from forelimb motor cortex stroke in the rat Neuroscience 167 2010 21 30
2. M. Alaverdashvili, and I.Q. Whishaw Motor cortex stroke impairs individual digit movement in skilled reaching by the rat Eur. J. Neurosci. 28 2008 311 322
3. V. Battistella, G.R. de Freitas, L.M. da Fonseca, D. Mercante, B. Gutfilen, R.C. Goldenberg, J.V. Dias, T.H. Kasai-Brunswick, E. Wajnberg, P.H. Rosado-de-Castro, S.V. Alves-Leon, R. Mendez-Otero, and C. Andre Safety of autologous bone marrow mononuclear cell transplantation in patients with nonacute ischemic stroke Regen. Med. 6 2011 45 52
4. L.I. Benowitz, and S.T. Carmichael Promoting axonal rewiring to improve outcome after stroke Neurobiol. Dis. 37 2010 259 266
5. J. Biernaskie, A. Szymanska, V. Windle, and D. Corbett Bi-hemispheric contribution to functional motor recovery of the affected forelimb following focal ischemic brain injury in rats Eur. J. Neurosci. 21 2005 989 999
6. M. Brenneman, S. Sharma, M. Harting, R. Strong, C.S. Cox Jr., J. Aronowski, J.C. Grotta, and S.I. Savitz Autologous bone marrow mononuclear cells enhance recovery after acute ischemic stroke in young and middle-aged rats J. Cereb. Blood Flow Metab. 30 2010 140 149
7. S.D. Bury, and T.A. Jones Unilateral sensorimotor cortex lesions in adult rats facilitate motor skill learning with the unaffected forelimb and trainining-induced dendritic structural plasticity in the motor cortex J. Neurosci. 22 2002 8597 8606
8. M. Chopp, and Y. Li Treatment of neural injury with marrow stromal cells Lancet Neurol. 1 2002 92 100
9. J.M. Conner, A. Culberson, C. Packowski, A.A. Chiba, and M.H. Tuszynski Lesions of the basal forebrain cholinergic system impair task acquisition and abolish cortical plasticity associated with motor skill learning Neuron 38 2003 819 829
10. B.J. Crain, S.D. Tran, and E. Mezey Transplanted human bone marrow cells generate new brain cells J. Neurol. Sci. 233 2005 121 123
11. A. de Vasconcelos dos Santos, J. da Costa Reis, B. Diaz Paredes, L. Moraes, Jasmin, A. Giraldi-Guimarães, and R. Mendez-Otero Therapeutic window for treatment of cortical ischemia with bone marrow-derived cells in rats 1306 2010 149 158 Brain Res. 1306 2010 149 158
12. O.A. Gharbawie, R.N. Auer, and I.Q. Whishaw Subcortical middle cerebral artery ischemia abolishes the digit flexion and closing used for grasping in rat skilled reaching Neuroscience 137 2006 1107 1118
13. A. Giraldi-Guimarães, M. Rezende-Lima, F.P. Bruno, and R. Mendez-Otero Treatment with bone marrow mononuclear cells induces functional recovery and decreases neurodegeneration after sensorimotor cortical ischemia in rats Brain Res. 1266 2009 108 120
14. M. Grabowski, P. Brundin, and B.B. Johansson Paw-reaching, sensorimotor, and rotational behavior after brain infarction in rats Stroke 24 1993 889 895
15. S. Iihoshi, O. Honmou, K. Houkin, K. Hashi, and J.D. Kocsis A therapeutic window for intravenous administration of autologous bone marrow after cerebral ischemia in adult rats Brain Res. 1007 2004 1 9
16. H. Jarratt, and B. Hyland Neuronal activity in rat red nucleus during forelimb reach-to-grasp movements Neuroscience 88 1999 629 642
17. T.A. Jones, C.J. Chu, L.A. Grande, and A.D. Gregory Motor skills training enhances lesion-induced structural plasticity in the motor cortex of adult rats J. Neurosci. 19 1999 10153 10163
18. N. Kamiya, M. Ueda, H. Igarashi, Y. Nishiyama, S. Suda, T. Inaba, and Y. Katayama Intra-arterial transplantation of bone marrow mononuclear cells immediately after reperfusion decreases brain injury after focal ischemia in rats Life Sci. 83 2008 433 437
19. J.A. Kleim, S. Barbay, and R.J. Nudo Functional reorganization of the rat motor cortex following motor skill learning J. Neurophysiol. 80 1998 3321 3325
20. J.A. Kleim, T.M. Hogg, P.M. VandenBerg, N.R. Cooper, R. Bruneau, and M. Remple Cortical synaptogenesis and motor map reorganization occur during late, but not early, phase of motor skill learning J. Neurosci. 24 2004 628 633
21. D.S. Krause, N.D. Theise, M.I. Collector, O. Henegariu, S. Hwang, R. Gardner, S. Neutzel, and S.J. Sharkis Multi-organ, multi-lineage engraftment by a single bone marrow-derived stem cell Cell 105 2001 369 377
22. Z. Liu, Y. Li, R.L. Zhang, Y. Cui, and M. Chopp Bone marrow stromal cells promote skilled motor recovery and enhance contralesional axonal connections after ischemic stroke in adult mice Stroke 42 2011 740 744
23. D.J. Maltman, S.A. Hardy, and S.A. Przyborski Role of mesenchymal stem cells in neurogenesis and nervous system repair Neurochem. Int. 59 2011 347 356
24. R. Mendez-Otero, G.R. de Freitas, C. André, M.L. de Mendonça, M. Friedrich, and J. Oliveira-Filho Potential roles of bone marrow stem cells in stroke therapy Regen. Med. 2 2007 417 423
25. E. Mezey Bone marrow-derived stem cells in neurological diseases: stones or masons? Regen. Med. 2 2007 37 49
26. M.H. Monfils, E.J. Plautz, and J.A. Kleim In search of the motor engram: motor map plasticity as a mechanism for encoding motor experience Neuroscientist 11 2005 471 483
27. R. Morris, A.P. Tosolini, J.D. Goldstein, and I.Q. Whishaw Impaired arpeggio movement in skilled reaching by rubrospinal tract lesions in the rat: a behavioral/anatomical fractionation J. Neurotrauma 282 2011 2439 2451
28. R.J. Nudo Postinfarct cortical plasticity and behavioral recovery Stroke 38 2007 840 845
29. S.H. Orkin Diversification of haematopoietic stem cells to specific lineages Nat. Rev. Genet. 1 2000 57 64
30. G. Paxinos, and C. Watson The Rat Brain in Stereotaxic Coordinates 5th ed. 2005 Elsevier Academic Press San Diego
31. J. Polentes, P. Jendelova, M. Cailleret, H. Braun, N. Romanyuk, P. Tropel, M. Brenot, V. Itier, C. Seminatore, K. Baldauf, K. Turnovcova, D. Jirak, M. Teletin, J. Côme, J. Tournois, K. Reymann, E. Sykova, S. Viville, and B. Onteniente Human induced pluripotent stem cells improve stroke outcome and reduce secondary degeneration in the recipient brain Cell Transplant. 2012
32. V. Riban, and M.F. Chesselet Region-specific sprouting of crossed corticofugal fibers after unilateral cortical lesions in adult mice Exp. Neurol. 197 2006 451 457
33. S.I. Savitz, V. Misra, M. Kasam, H. Juneja, C.S. Cox Jr., S. Alderman, I. Aisiku, S. Kar, A. Gee, and J.C. Grotta Intravenous autologous bone marrow mononuclear cells for ischemic stroke Ann. Neurol. 70 2011 59 69
34. K.L. Schaar, M.M. Brenneman, and S.I. Savitz Functional assessments in the rodent stroke model Exp. Transl. Stroke Med. 2 2010 1 11
35. T. Schallert Behavioral tests for preclinical intervention assessment NeuroRx 3 2006 497 504
36. W.C. Shyu, Y.J. Lee, D.D. Liu, S.Z. Lin, and H. Li Homing genes, cell therapy and stroke Front. Biosci. 11 2006 899 907
37. F.G. Szele, C. Alexander, and M.F. Chesselet Expression of molecules associated with neuronal plasticity in the striatum after aspiration and thermocoagulatory lesions of the cerebral cortex in adult rats J. Neurosci. 15 1995 4429 4448
38. M. Takahashi, T.S. Li, R. Suzuki, T. Kobayashi, H. Ito, Y. Ikeda, M. Matsuzaki, and K. Hamano Cytokines produced by bone marrow cells can contribute to functional improvement of the infarcted heart by protecting cardiomyocytes from ischemic injury Am. J. Physiol. Heart Circ. Physiol. 291 2006 886 893
39. Q.R. Wang, B.H. Wang, Y.H. Huang, G. Dai, W.M. Li, and Q. Yan Purification and growth of endothelial progenitor cells from murine bone marrow mononuclear cells J. Cell Biochem. 103 2008 21 29
40. I.L. Weissman, D.J. Anderson, and F. Gage Stem and progenitor cells: origins, phenotypes, lineage commitments, and transdifferentiations Annu. Rev. Cell Dev. Biol. 17 2001 387 403
41. B. Yang, R. Strong, S. Sharma, M. Brenneman, K. Mallikarjunarao, X. Xi, J.C. Grotta, J. Aronowski, and S.I. Savitz Therapeutic time window and dose response of autologous bone marrow mononuclear cells for ischemic stroke J. Neurosci. Res. 89 2011 833 839
42. L. Zai, C. Ferrari, S. Subbaiah, L.A. Havton, G. Coppola, S. Strittmatter, N. Irwin, D. Geschwind, and L.I. Benowitz Inosine alters gene expression and axonal projections in neurons contralateral to a cortical infarct and improves skilled use of the impaired limb J. Neurosci. 29 2009 8187 8197