Inosine alters gene expression and axonal projections in neurons contralateral to a cortical infarct and improves skilled use of the impaired limb

Journal of Neuroscience

Volumn 29, Issue 25, 2009, Pages 8187-8197

  Zai, Laila ^a   Ferrari, Christina ^a   Subbaiah, Sathish ^a,b   Havton, Leif A ^c   Coppola, Giovanni ^c   Strittmatter, Stephen ^d   Irwin, Nina ^a,b   Geschwind, Daniel ^c   Benowitz, Larry I ^a,b  

^a BOSTON CHILDREN S HOSPITAL   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

INOSINE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BEHAVIOR; BRAIN CORTEX; BRAIN INFARCTION; BRAIN INJURY; CONTROLLED STUDY; CONVALESCENCE; DENERVATION; DISEASE MODEL; FEMALE; FOOD INTAKE; FOREFOOT; GENE CONTROL; GENE EXPRESSION; GENE FUNCTION; GENETIC TRANSCRIPTION; GRIP STRENGTH; HEMISPHERE; IMMUNOHISTOCHEMISTRY; LASER CAPTURE MICRODISSECTION; LIMB MOVEMENT; MICROARRAY ANALYSIS; NERVE FIBER GROWTH; NERVE PROJECTION; NONHUMAN; PRIORITY JOURNAL; PYRAMIDAL TRACT; QUANTITATIVE ANALYSIS; RAT; SENSORIMOTOR CORTEX; SPINAL CORD; STROKE; SURVIVAL TIME; SYNAPSE; UPREGULATION;

ANIMALS; AXONS; BRAIN INFARCTION; CEREBRAL CORTEX; COMPLEMENT C1Q; COMPLEMENT C3; DISEASE MODELS, ANIMAL; EXTREMITIES; FUNCTIONAL LATERALITY; GENE EXPRESSION REGULATION; HEAT-SHOCK PROTEINS; IMMUNOHISTOCHEMISTRY; INJECTIONS, INTRAVENTRICULAR; INOSINE; NEURONS; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PROTEASOME ENDOPEPTIDASE COMPLEX; RATS; RATS, SPRAGUE-DAWLEY; RECOVERY OF FUNCTION; RNA, MESSENGER; TREATMENT OUTCOME; UBIQUITINATION;

EID: 67649321875     PISSN: 02706474     EISSN: 15292401     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.0414-09.2009     Document Type: Article

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