-
1
-
-
70450270900
-
Awakening guardian angels: Drugging the p53 pathway
-
Brown CJ, Lain S, Verma CS, Fersht AR, Lane DP (2009) Awakening guardian angels: drugging the p53 pathway. Nat Rev Cancer 9:862-873
-
(2009)
Nat Rev Cancer
, vol.9
, pp. 862-873
-
-
Brown, C.J.1
Lain, S.2
Verma, C.S.3
Fersht, A.R.4
Lane, D.P.5
-
2
-
-
0035751937
-
Assessing TP53 status in human tumours to evaluate clinical outcome
-
Soussi T, Beroud C (2001) Assessing TP53 status in human tumours to evaluate clinical outcome. Nat Rev Cancer 1:233-240
-
(2001)
Nat Rev Cancer
, vol.1
, pp. 233-240
-
-
Soussi, T.1
Beroud, C.2
-
3
-
-
65949083750
-
Cytoplasmic functions of the tumour suppressor p53
-
Green DR, Kroemer G (2009) Cytoplasmic functions of the tumour suppressor p53. Nature 458:1127-1130
-
(2009)
Nature
, vol.458
, pp. 1127-1130
-
-
Green, D.R.1
Kroemer, G.2
-
4
-
-
78149412314
-
Dynamics of microRNA biogenesis: Crosstalk between p53 network and microRNA processing pathway
-
Suzuki HI, Miyazono K (2010) Dynamics of microRNA biogenesis: crosstalk between p53 network and microRNA processing pathway. J Mol Med 88:1085-1094
-
(2010)
J Mol Med
, vol.88
, pp. 1085-1094
-
-
Suzuki, H.I.1
Miyazono, K.2
-
5
-
-
77955902024
-
The widespread regulation of microRNA biogenesis, function and decay
-
Krol J, Loedige I, Filipowicz W (2010) The widespread regulation of microRNA biogenesis, function and decay. Nat Rev Genet 11:597-610
-
(2010)
Nat Rev Genet
, vol.11
, pp. 597-610
-
-
Krol, J.1
Loedige, I.2
Filipowicz, W.3
-
6
-
-
25444457833
-
MicroRNAs: Critical regulators of development, cellular physiology and malignancy
-
Mendell JT (2005) MicroRNAs: critical regulators of development, cellular physiology and malignancy. Cell Cycle 4:1179-1184
-
(2005)
Cell Cycle
, vol.4
, pp. 1179-1184
-
-
Mendell, J.T.1
-
7
-
-
9144225636
-
The Microprocessor complex mediates the genesis of microRNAs
-
Gregor y RI, Yan KP, Amuthan G, Chendrimada T, Doratotaj B, Cooch N et al (2004) The Microprocessor complex mediates the genesis of microRNAs. Nature 432:235-240
-
(2004)
Nature
, vol.432
, pp. 235-240
-
-
Gregory, R.I.1
Yan, K.P.2
Amuthan, G.3
Chendrimada, T.4
Doratotaj, B.5
Cooch, N.6
-
8
-
-
0141843656
-
The nuclear RNase III Drosha initiates microRNA processing
-
Lee Y, Ahn C, Han J, Choi H, Kim J, Yim J et al (2003) The nuclear RNase III Drosha initiates microRNA processing. Nature 425: 415-419
-
(2003)
Nature
, vol.425
, pp. 415-419
-
-
Lee, Y.1
Ahn, C.2
Han, J.3
Choi, H.4
Kim, J.5
Yim, J.6
-
9
-
-
33744520104
-
Molecular basis for the recognition of primary microRNAs by the Drosha-DGCR8 complex
-
Han J, Lee Y, Yeom KH, Nam JW, Heo I, Rhee JK et al (2006) Molecular basis for the recognition of primary microRNAs by the Drosha-DGCR8 complex. Cell 125: 887-901
-
(2006)
Cell
, vol.125
, pp. 887-901
-
-
Han, J.1
Lee, Y.2
Yeom, K.H.3
Nam, J.W.4
Heo, I.5
Rhee, J.K.6
-
10
-
-
34247876168
-
DEAD-box RNA helicase subunits of the Drosha complex are required for processing of rRNA and a subset of microRNAs
-
Fukuda T, Yamagata K, Fujiyama S, Matsumoto T, Koshida I, Yoshimura K et al (2007) DEAD-box RNA helicase subunits of the Drosha complex are required for processing of rRNA and a subset of microRNAs. Nat Cell Biol 9: 604-611
-
(2007)
Nat Cell Biol
, vol.9
, pp. 604-611
-
-
Fukuda, T.1
Yamagata, K.2
Fujiyama, S.3
Matsumoto, T.4
Koshida, I.5
Yoshimura, K.6
-
11
-
-
0347361541
-
Exportin-5 mediates the nuclear export of pre-microRNAs and short hairpin RNAs
-
Yi R, Qin Y, Macara IG, Cullen BR (2003) Exportin-5 mediates the nuclear export of pre-microRNAs and short hairpin RNAs. Genes Dev 17:3011-3016
-
(2003)
Genes Dev
, vol.17
, pp. 3011-3016
-
-
Yi, R.1
Qin, Y.2
MacAra, I.G.3
Cullen, B.R.4
-
12
-
-
27744537851
-
Human RISC couples microRNA biogenesis and posttranscriptional gene silencing
-
Gregory RI, Chendrimada TP, Cooch N, Shiekhattar R (2005) Human RISC couples microRNA biogenesis and posttranscriptional gene silencing. Cell 123:631-640
-
(2005)
Cell
, vol.123
, pp. 631-640
-
-
Gregory, R.I.1
Chendrimada, T.P.2
Cooch, N.3
Shiekhattar, R.4
-
13
-
-
78650639749
-
Emerging complexity of microRNA generation cascades
-
Suzuki HI, Miyazono K (2011) Emerging complexity of microRNA generation cascades. J Biochem 149(1):15-25
-
(2011)
J Biochem
, vol.149
, Issue.1
, pp. 15-25
-
-
Suzuki, H.I.1
Miyazono, K.2
-
14
-
-
34250851115
-
A microRNA component of the p53 tumour suppressor network
-
He L, He X, Lim LP, de Stanchina E, Xuan Z, Liang Y et al (2007) A microRNA component of the p53 tumour suppressor network. Nature 447:1130-1134
-
(2007)
Nature
, vol.447
, pp. 1130-1134
-
-
He, L.1
He, X.2
Lim, L.P.3
De Stanchina, E.4
Xuan, Z.5
Liang, Y.6
-
15
-
-
34249817549
-
Transactivation of miR-34a by p53 broadly in fluences gene expression and promotes apoptosis
-
Chang TC, Wentzel EA, Kent OA, Ramachandran K, Mullendore M, Lee KH et al (2007) Transactivation of miR-34a by p53 broadly in fluences gene expression and promotes apoptosis. Mol Cell 26:745-752
-
(2007)
Mol Cell
, vol.26
, pp. 745-752
-
-
Chang, T.C.1
Wentzel, E.A.2
Kent, O.A.3
Ramachandran, K.4
Mullendore, M.5
Lee, K.H.6
-
16
-
-
34249822779
-
Transcriptional activation of miR-34a contributes to p53-mediated apoptosis
-
Raver-Shapira N, Marciano E, Meiri E, Spector Y, Rosenfeld N, Moskovits N et al (2007) Transcriptional activation of miR-34a contributes to p53-mediated apoptosis. Mol Cell 26:731-743
-
(2007)
Mol Cell
, vol.26
, pp. 731-743
-
-
Raver-Shapira, N.1
Marciano, E.2
Meiri, E.3
Spector, Y.4
Rosenfeld, N.5
Moskovits, N.6
-
17
-
-
34250868124
-
Differential regulation of microRNAs by p53 revealed by massively parallel sequencing: MiR-34a is a p53 target that induces apoptosis and G1-arrest
-
Tarasov V, Jung P, Verdoodt B, Lodygin D, Epanchintsev A, Menssen A et al (2007) Differential regulation of microRNAs by p53 revealed by massively parallel sequencing: miR-34a is a p53 target that induces apoptosis and G1-arrest. Cell Cycle 6:1586-1593
-
(2007)
Cell Cycle
, vol.6
, pp. 1586-1593
-
-
Tarasov, V.1
Jung, P.2
Verdoodt, B.3
Lodygin, D.4
Epanchintsev, A.5
Menssen, A.6
-
18
-
-
57749099102
-
P53-Responsive micrornas 192 and 215 are capable of inducing cell cycle arrest
-
Braun CJ, Zhang X, Savelyeva I, Wolff S, Moll UM, Schepeler T et al (2008) p53-Responsive micrornas 192 and 215 are capable of inducing cell cycle arrest. Cancer Res 68:10094-10104
-
(2008)
Cancer Res
, vol.68
, pp. 10094-10104
-
-
Braun, C.J.1
Zhang, X.2
Savelyeva, I.3
Wolff, S.4
Moll, U.M.5
Schepeler, T.6
-
19
-
-
57749116172
-
Coordinated regulation of cell cycle transcripts by p53-Inducible microRNAs, miR-192 and miR-215
-
Georges SA, Biery MC, Kim SY, Schelter JM, Guo J, Chang AN et al (2008) Coordinated regulation of cell cycle transcripts by p53-Inducible microRNAs, miR-192 and miR-215. Cancer Res 68:10105-10112
-
(2008)
Cancer Res
, vol.68
, pp. 10105-10112
-
-
Georges, S.A.1
Biery, M.C.2
Kim, S.Y.3
Schelter, J.M.4
Guo, J.5
Chang, A.N.6
-
20
-
-
70349220767
-
Repression of the miR-17-92 cluster by p53 has an important function in hypoxia-induced apoptosis
-
Yan HL, Xue G, Mei Q, Wang YZ, Ding FX, Liu MF et al (2009) Repression of the miR-17-92 cluster by p53 has an important function in hypoxia-induced apoptosis. EMBO J 28: 2719-2732
-
(2009)
EMBO J
, vol.28
, pp. 2719-2732
-
-
Yan, H.L.1
Xue, G.2
Mei, Q.3
Wang, Y.Z.4
Ding, F.X.5
Liu, M.F.6
-
21
-
-
67749143728
-
Modulation of microRNA processing by p53
-
Suzuki HI, Yamagata K, Sugimoto K, Iwamoto T, Kato S, Miyazono K (2009) Modulation of microRNA processing by p53. Nature 460:529-533
-
(2009)
Nature
, vol.460
, pp. 529-533
-
-
Suzuki, H.I.1
Yamagata, K.2
Sugimoto, K.3
Iwamoto, T.4
Kato, S.5
Miyazono, K.6
-
22
-
-
67651149479
-
MicroRNA-mediated gene silencing modulates the UV-induced DNA-damage response
-
Pothof J, Verkaik NS, van Ijcken IW, Wiemer EA, Ta VT, van der Horst GT et al (2009) MicroRNA-mediated gene silencing modulates the UV-induced DNA-damage response. EMBO J 28:2090-2099
-
(2009)
EMBO J
, vol.28
, pp. 2090-2099
-
-
Pothof, J.1
Verkaik, N.S.2
Van Ijcken, I.W.3
Wiemer, E.A.4
Ta, V.T.5
Van Der Horst, G.T.6
-
23
-
-
20044373828
-
The DEAD box protein p68: A novel transcriptional coactivator of the p53 tumour suppressor
-
Bates GJ, Nicol SM, Wilson BJ, Jacobs AM, Bourdon JC, Wardrop J et al (2005) The DEAD box protein p68: a novel transcriptional coactivator of the p53 tumour suppressor. EMBO J 24:543-553
-
(2005)
EMBO J
, vol.24
, pp. 543-553
-
-
Bates, G.J.1
Nicol, S.M.2
Wilson, B.J.3
Jacobs, A.M.4
Bourdon, J.C.5
Wardrop, J.6
-
24
-
-
58149215802
-
MiR-29 miRNAs activate p53 by targeting p85 alpha and CDC42
-
Park SY, Lee JH, Ha M, Nam JW, Kim VN (2009) miR-29 miRNAs activate p53 by targeting p85 alpha and CDC42. Nat Struct Mol Biol 16:23-29
-
(2009)
Nat Struct Mol Biol
, vol.16
, pp. 23-29
-
-
Park, S.Y.1
Lee, J.H.2
Ha, M.3
Nam, J.W.4
Kim, V.N.5
-
25
-
-
64349101658
-
MicroRNA-125b is a novel negative regulator of p53
-
Le MT, Teh C, Shyh-Chang N, Xie H, Zhou B, Korzh V et al (2009) MicroRNA-125b is a novel negative regulator of p53. Genes Dev 23:862-876
-
(2009)
Genes Dev
, vol.23
, pp. 862-876
-
-
Le, M.T.1
Teh, C.2
Shyh-Chang, N.3
Xie, H.4
Zhou, B.5
Korzh, V.6
-
26
-
-
67651007766
-
MiR-122/cyclin G1 interaction modulates p53 activity and affects doxorubicin sensitivity of human hepatocarcinoma cells
-
Fornari F, Gramantieri L, Giovannini C, Veronese A, Ferracin M, Sabbioni S et al (2009) MiR-122/cyclin G1 interaction modulates p53 activity and affects doxorubicin sensitivity of human hepatocarcinoma cells. Cancer Res 69:5761-5767
-
(2009)
Cancer Res
, vol.69
, pp. 5761-5767
-
-
Fornari, F.1
Gramantieri, L.2
Giovannini, C.3
Veronese, A.4
Ferracin, M.5
Sabbioni, S.6
-
27
-
-
33646056975
-
A genetic screen implicates miRNA-372 and miRNA-373 as oncogenes in testicular germ cell tumors
-
Voorhoeve PM, le Sage C, Schrier M, Gillis AJ, Stoop H, Nagel R et al (2006) A genetic screen implicates miRNA-372 and miRNA-373 as oncogenes in testicular germ cell tumors. Cell 124:1169-1181
-
(2006)
Cell
, vol.124
, pp. 1169-1181
-
-
Voorhoeve, P.M.1
Le Sage, C.2
Schrier, M.3
Gillis, A.J.4
Stoop, H.5
Nagel, R.6
-
28
-
-
46249107572
-
Loss of miRNA biogenesis induces p19Arf-p53 signaling and senescence in primary cells
-
Mudhasani R, Zhu Z, Hutvagner G, Eischen CM, Lyle S, Hall LL et al (2008) Loss of miRNA biogenesis induces p19Arf-p53 signaling and senescence in primary cells. J Cell Biol 181:1055-1063
-
(2008)
J Cell Biol
, vol.181
, pp. 1055-1063
-
-
Mudhasani, R.1
Zhu, Z.2
Hutvagner, G.3
Eischen, C.M.4
Lyle, S.5
Hall, L.L.6
-
29
-
-
77958558613
-
TAp63 suppresses metastasis through coordinate regulation of Dicer and miRNAs
-
Su X, Chakravarti D, Cho MS, Liu L, Gi YJ, Lin YL et al (2010) TAp63 suppresses metastasis through coordinate regulation of Dicer and miRNAs. Nature 467:986-990
-
(2010)
Nature
, vol.467
, pp. 986-990
-
-
Su, X.1
Chakravarti, D.2
Cho, M.S.3
Liu, L.4
Gi, Y.J.5
Lin, Y.L.6
-
30
-
-
79952278023
-
Quantitation of microRNAs by realtime RT-qPCR
-
Chen C, Tan R, Wong L, Fekete R, Halsey J (2011) Quantitation of microRNAs by realtime RT-qPCR. Methods Mol Biol 687: 113-134
-
(2011)
Methods Mol Biol
, vol.687
, pp. 113-134
-
-
Chen, C.1
Tan, R.2
Wong, L.3
Fekete, R.4
Halsey, J.5
-
31
-
-
0036354884
-
Reversible cross-linking combined with immunoprecipitation to study RNA-protein interactions in vivo
-
Niranjanakumari S, Lasda E, Brazas R, Garcia-Blanco MA (2002) Reversible cross-linking combined with immunoprecipitation to study RNA-protein interactions in vivo. Methods 26:182-190
-
(2002)
Methods
, vol.26
, pp. 182-190
-
-
Niranjanakumari, S.1
Lasda, E.2
Brazas, R.3
Garcia-Blanco, M.A.4
-
32
-
-
33344461310
-
A transient heterochromatic state in Xist preempts X inactivation choice without RNA stabilization
-
Sun BK, Deaton AM, Lee JT (2006) A transient heterochromatic state in Xist preempts X inactivation choice without RNA stabilization. Mol Cell 21:617-628
-
(2006)
Mol Cell
, vol.21
, pp. 617-628
-
-
Sun, B.K.1
Deaton, A.M.2
Lee, J.T.3
-
33
-
-
33746041435
-
Drosophila ribosomal proteins are associated with linker histone H1 and suppress gene transcription
-
Ni JQ, Liu LP, Hess D, Rietdorf J, Sun FL (2006) Drosophila ribosomal proteins are associated with linker histone H1 and suppress gene transcription. Genes Dev 20:1959-1973
-
(2006)
Genes Dev
, vol.20
, pp. 1959-1973
-
-
Ni, J.Q.1
Liu, L.P.2
Hess, D.3
Rietdorf, J.4
Sun, F.L.5
-
34
-
-
33749047034
-
MicroRNA biogenesis: Isolation and characterization of the microprocessor complex
-
Gregory RI, Chendrimada TP, Shiekhattar R (2006) MicroRNA biogenesis: isolation and characterization of the microprocessor complex. Methods Mol Biol 342:33-47
-
(2006)
Methods Mol Biol
, vol.342
, pp. 33-47
-
-
Gregory, R.I.1
Chendrimada, T.P.2
Shiekhattar, R.3
-
35
-
-
33749077732
-
In vitro precursor microRNA processing assays using Drosophila Schneider-2 cell lysates
-
Ishizuka A, Saito K, Siomi MC, Siomi H (2006) In vitro precursor microRNA processing assays using Drosophila Schneider-2 cell lysates. Methods Mol Biol 342:277-286
-
(2006)
Methods Mol Biol
, vol.342
, pp. 277-286
-
-
Ishizuka, A.1
Saito, K.2
Siomi, M.C.3
Siomi, H.4
|