Alpha B-crystallin prevents the arrhythmogenic effects of particulate matter isolated from ambient air by attenuating oxidative stress

Toxicology and Applied Pharmacology

Volumn 266, Issue 2, 2013, Pages 267-275

  Park, Hyelim ^a,b   Park, Sanghoon ^a   Jeon, Hyunju ^a   Song, Byeong Wook ^a,b   Kim, Jin Bae ^c   Kim, Chang Soo ^a   Pak, Hui Nam ^a   Hwang, Ki Chul ^a,b   Lee, Moon Hyoung ^a   Chung, Ji Hyung ^a   Joung, Boyoung ^a,b  

^a Yonsei University College of Medicine   (South Korea)

^b Yonsei University   (South Korea)

^c Kyung Hee University Hospital   (South Korea)

Author keywords

Air pollution; Arrhythmia; Ca2+ calmodulin dependent protein kinase II; Heat shock protein; Particulate matter

Indexed keywords

ALPHA CRYSTALLIN; BETA CRYSTALLIN; CALCIUM CALMODULIN DEPENDENT PROTEIN KINASE II; HEAT SHOCK PROTEIN; REACTIVE OXYGEN METABOLITE; TRANSACTIVATOR PROTEIN; TRANSACTIVATOR PROTEIN ALPHA BETA CRYSTALLIN; UNCLASSIFIED DRUG;

ACTION POTENTIAL; AMBIENT AIR; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARRHYTHMOGENESIS; ARTICLE; CONTROLLED STUDY; EXHAUST GAS; HEART MUSCLE CELL; HEART VENTRICLE EXTRASYSTOLE; MALE; NONHUMAN; OXIDATIVE STRESS; PARTICULATE MATTER; QT INTERVAL; RAT; TRACHEA;

ACTION POTENTIALS; AIR POLLUTANTS; ALPHA-CRYSTALLIN B CHAIN; ANIMALS; ARRHYTHMIAS, CARDIAC; CALCIUM-CALMODULIN-DEPENDENT PROTEIN KINASE TYPE 2; MALE; MYOCYTES, CARDIAC; OXIDATIVE STRESS; PARTICULATE MATTER; RATS; RATS, SPRAGUE-DAWLEY; REACTIVE OXYGEN SPECIES; VEHICLE EMISSIONS; VENTRICULAR PREMATURE COMPLEXES;

RATTUS;

EID: 84871839836     PISSN: 0041008X     EISSN: 10960333     Source Type: Journal    
DOI: 10.1016/j.taap.2012.10.013     Document Type: Article

References (33)

1. Benjamin I.J., McMillan D.R. Stress (heat shock) proteins: molecular chaperones in cardiovascular biology and disease. Circ. Res. 1998, 83:117-132.
2. Brook R.D., Franklin B., Cascio W., Hong Y., Howard G., Lipsett M., Luepker R., Mittleman M., Samet J., Smith S.C., Tager I. Air pollution and cardiovascular disease: a statement for healthcare professionals from the Expert Panel on Population and Prevention Science of the American Heart Association. Circulation 2004, 109:2655-2671.
3. Cozzi E., Hazarika S., Stallings H.W., Cascio W.E., Devlin R.B., Lust R.M., Wingard C.J., Van Scott M.R. Ultrafine particulate matter exposure augments ischemia-reperfusion injury in mice. Am. J. Physiol. Heart Circ. Physiol. 2006, 291:H894-H903.
4. Devlin R.B., Ghio A.J., Kehrl H., Sanders G., Cascio W. Elderly humans exposed to concentrated air pollution particles have decreased heart rate variability. Eur. Respir. J. Suppl. 2003, 40:76s-80s.
5. Dockery D.W., Luttmann-Gibson H., Rich D.Q., Link M.S., Mittleman M.A., Gold D.R., Koutrakis P., Schwartz J.D., Verrier R.L. Association of air pollution with increased incidence of ventricular tachyarrhythmias recorded by implanted cardioverter defibrillators. Environ. Health Perspect. 2005, 113:670-674.
6. Erickson J.R., Joiner M.L., Guan X., Kutschke W., Yang J., Oddis C.V., Bartlett R.K., Lowe J.S., O'Donnell S.E., Aykin-Burns N., Zimmerman M.C., Zimmerman K., Ham A.J., Weiss R.M., Spitz D.R., Shea M.A., Colbran R.J., Mohler P.J., Anderson M.E. A dynamic pathway for calcium-independent activation of CaMKII by methionine oxidation. Cell 2008, 133:462-474.
7. Fedorov V.V., Lozinsky I.T., Sosunov E.A., Anyukhovsky E.P., Rosen M.R., Balke C.W., Efimov I.R. Application of blebbistatin as an excitation-contraction uncoupler for electrophysiologic study of rat and rabbit hearts. Hear. Rhythm. 2007, 4:619-626.
8. Garfinkel A., Kim Y.H., Voroshilovsky O., Qu Z., Kil J.R., Lee M.H., Karagueuzian H.S., Weiss J.N., Chen P.S. Preventing ventricular fibrillation by flattening cardiac restitution. Proc. Natl. Acad. Sci. U. S. A. 2000, 97:6061-6066.
9. Golenhofen N., Redel A., Wawrousek E.F., Drenckhahn D. Ischemia-induced increase of stiffness of alphaB-crystallin/HSPB2-deficient myocardium. Pflugers Arch. 2006, 451:518-525.
10. Hoek G., Brunekreef B., Fischer P., van Wijnen J. The association between air pollution and heart failure, arrhythmia, embolism, thrombosis, and other cardiovascular causes of death in a time series study. Epidemiology 2001, 12:355-357.
11. Kadono T., Zhang X.Q., Srinivasan S., Ishida H., Barry W.H., Benjamin I.J. CRYAB and HSPB2 deficiency increases myocyte mitochondrial permeability transition and mitochondrial calcium uptake. J. Mol. Cell. Cardiol. 2006, 40:783-789.
12. Kappe G., Franck E., Verschuure P., Boelens W.C., Leunissen J.A., de Jong W.W. The human genome encodes 10 alpha-crystallin-related small heat shock proteins: HspB1-10. Cell Stress Chaperones 2003, 8:53-61.
13. Kim J.B., Kim C., Choi E., Park S., Park H., Pak H.N., Lee M.H., Shin D.C., Hwang K.C., Joung B. Particulate air pollution induces arrhythmia via oxidative stress and calcium calmodulin kinase II activation. Toxicol. Appl. Pharmacol. 2012, 259:66-73.
14. Kwon J.H., Kim J.B., Lee K.H., Kang S.M., Chung N., Jang Y., Chung J.H. Protective effect of heat shock protein 27 using protein transduction domain-mediated delivery on ischemia/reperfusion heart injury. Biochem. Biophys. Res. Commun. 2007, 363:399-404.
15. Ljungman P.L., Berglind N., Holmgren C., Gadler F., Edvardsson N., Pershagen G., Rosenqvist M., Sjogren B., Bellander T. Rapid effects of air pollution on ventricular arrhythmias. Eur. Heart J. 2008, 29:2894-2901.
16. Maloyan A., Sanbe A., Osinska H., Westfall M., Robinson D., Imahashi K., Murphy E., Robbins J. Mitochondrial dysfunction and apoptosis underlie the pathogenic process in alpha-B-crystallin desmin-related cardiomyopathy. Circulation 2005, 112:3451-3461.
17. Morrison L.E., Whittaker R.J., Klepper R.E., Wawrousek E.F., Glembotski C.C. Roles for alphaB-crystallin and HSPB2 in protecting the myocardium from ischemia-reperfusion-induced damage in a KO mouse model. Am. J. Physiol. Heart Circ. Physiol. 2004, 286:H847-H855.
18. Nemmar A., Hoet P.H., Vanquickenborne B., Dinsdale D., Thomeer M., Hoylaerts M.F., Vanbilloen H., Mortelmans L., Nemery B. Passage of inhaled particles into the blood circulation in humans. Circulation 2002, 105:411-414.
19. Pastore J.M., Girouard S.D., Laurita K.R., Akar F.G., Rosenbaum D.S. Mechanism linking T-wave alternans to the genesis of cardiac fibrillation. Circulation 1999, 99:1385-1394.
20. Perng M.D., Muchowski P.J., van Den I.P., Wu G.J., Hutcheson A.M., Clark J.I., Quinlan R.A. The cardiomyopathy and lens cataract mutation in alphaB-crystallin alters its protein structure, chaperone activity, and interaction with intermediate filaments in vitro. J. Biol. Chem. 1999, 274:33235-33243.
21. Peters A., Dockery D.W., Muller J.E., Mittleman M.A. Increased particulate air pollution and the triggering of myocardial infarction. Circulation 2001, 103:2810-2815.
22. Pope C.A., Burnett R.T., Thurston G.D., Thun M.J., Calle E.E., Krewski D., Godleski J.J. Cardiovascular mortality and long-term exposure to particulate air pollution: epidemiological evidence of general pathophysiological pathways of disease. Circulation 2004, 109:71-77.
23. Rajasekaran N.S., Connell P., Christians E.S., Yan L.J., Taylor R.P., Orosz A., Zhang X.Q., Stevenson T.J., Peshock R.M., Leopold J.A., Barry W.H., Loscalzo J., Odelberg S.J., Benjamin I.J. Human alpha B-crystallin mutation causes oxido-reductive stress and protein aggregation cardiomyopathy in mice. Cell 2007, 130:427-439.
24. Ray P.S., Martin J.L., Swanson E.A., Otani H., Dillmann W.H., Das D.K. Transgene overexpression of alphaB crystallin confers simultaneous protection against cardiomyocyte apoptosis and necrosis during myocardial ischemia and reperfusion. FASEB J. 2001, 15:393-402.
25. Salama G., Lombardi R., Elson J. Maps of optical action potentials and NADH fluorescence in intact working hearts. Am. J. Physiol. 1987, 252:H384-H394.
26. Song Y., Shryock J.C., Wagner S., Maier L.S., Belardinelli L. Blocking late sodium current reduces hydrogen peroxide-induced arrhythmogenic activity and contractile dysfunction. J. Pharmacol. Exp. Ther. 2006, 318:214-222.
27. Szentadrassy N., Banyasz T., Biro T., Szabo G., Toth B.I., Magyar J., Lazar J., Varro A., Kovacs L., Nanasi P.P. Apico-basal inhomogeneity in distribution of ion channels in canine and human ventricular myocardium. Cardiovasc. Res. 2005, 65:851-860.
28. Tobias H.J., Beving D.E., Ziemann P.J., Sakurai H., Zuk M., McMurry P.H., Zarling D., Waytulonis R., Kittelson D.B. Chemical analysis of diesel engine nanoparticles using a nano-DMA/thermal desorption particle beam mass spectrometer. Environ. Sci. Technol. 2001, 35:2233-2243.
29. Velotta J.B., Kimura N., Chang S.H., Chung J., Itoh S., Rothbard J., Yang P.C., Steinman L., Robbins R.C., Fischbein M.P. alphaB-crystallin improves murine cardiac function and attenuates apoptosis in human endothelial cells exposed to ischemia-reperfusion. Ann. Thorac. Surg. 2011, 91:1907-1913.
30. Vila-Petroff M., Salas M.A., Said M., Valverde C.A., Sapia L., Portiansky E., Hajjar R.J., Kranias E.G., Mundina-Weilenmann C., Mattiazzi A. CaMKII inhibition protects against necrosis and apoptosis in irreversible ischemia-reperfusion injury. Cardiovasc. Res. 2007, 73:689-698.
31. Xie L.H., Chen F., Karagueuzian H.S., Weiss J.N. Oxidative-stress-induced afterdepolarizations and calmodulin kinase II signaling. Circ. Res. 2009, 104:79-86.
32. Xiong C., Friedlander S.K. Morphological properties of atmospheric aerosol aggregates. Proc. Natl. Acad. Sci. U. S. A. 2001, 98:11851-11856.
33. Zhang R., Khoo M.S., Wu Y., Yang Y., Grueter C.E., Ni G., Price E.E., Thiel W., Guatimosim S., Song L.S., Madu E.C., Shah A.N., Vishnivetskaya T.A., Atkinson J.B., Gurevich V.V., Salama G., Lederer W.J., Colbran R.J., Anderson M.E. Calmodulin kinase II inhibition protects against structural heart disease. Nat. Med. 2005, 11:409-417.