αb-crystallin improves murine cardiac function and attenuates apoptosis in human endothelial cells exposed to ischemia-reperfusion

Annals of Thoracic Surgery

Volumn 91, Issue 6, 2011, Pages 1907-1913

  Velotta, Jeffrey B ^a   Kimura, Naoyuki ^a   Chang, Stephanie H ^a   Chung, Jaehoon ^a   Itoh, Satoshi ^a   Rothbard, Jonathan ^a   Yang, Philip C ^a   Steinman, Lawrence ^a   Robbins, Robert C ^a   Fischbein, Michael P ^a  

^a STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CASPASE 3; CASPASE 9; CRYAB PROTEIN; DNA FRAGMENT; HEAT SHOCK PROTEIN; PROTEIN BAX; PROTEIN BCL 2; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; CONTROLLED STUDY; DRUG EFFECT; DRUG MECHANISM; ENDOTHELIUM CELL; ENZYME ACTIVITY; ENZYME LINKED IMMUNOSORBENT ASSAY; HEART FUNCTION; HEART INFARCTION; HEART LEFT VENTRICLE EJECTION FRACTION; HEART MUSCLE CELL; HUMAN; HUMAN CELL; HYPOXIA; IN VITRO STUDY; IN VIVO CULTURE; ISCHEMIA; LEFT ANTERIOR DESCENDING CORONARY ARTERY; MICROVASCULAR ENDOTHELIAL CELL; MOUSE; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; NUCLEOTIDE SEQUENCE; POSTOPERATIVE PERIOD; PRIORITY JOURNAL; PROTEIN EXPRESSION; REOXYGENATION; REPERFUSION; REPERFUSION INJURY; WESTERN BLOTTING;

ALPHA-CRYSTALLIN B CHAIN; ANIMALS; APOPTOSIS; CELL LINE; ENDOTHELIAL CELLS; HUMANS; MALE; MICE; MICE, INBRED C57BL; MYOCARDIAL REPERFUSION INJURY; MYOCYTES, CARDIAC; VENTRICULAR FUNCTION, LEFT;

EID: 79957705137     PISSN: 00034975     EISSN: 15526259     Source Type: Journal    
DOI: 10.1016/j.athoracsur.2011.02.072     Document Type: Article

References (30)

1. Lutsch G, Vetter R, Offhauss U, et al. Abundance and location of the small heat shock proteins HSP25 and alphaB-crystallin in rat and human heart. Circulation 1997;96:3466-76. (Pubitemid 27513421)
2. Kamradt MC, Lu M, Werner ME, et al. The small heat shock protein alpha B-crystallin is a novel inhibitor of TRAIL-induced apoptosis that suppresses the activation of caspase-3. J Biol Chem 2005;280:11059-66. (Pubitemid 40418409)
3. Morrison LE, Hoover HE, Therauf DJ, Glembotski CC. Mimicking phosphorylation of alphaB-crystallin on serine-59 is necessary and sufficient to provide maximal protection of cardiac myocytes from apoptosis. Circ Res 2003; 92:203-11. (Pubitemid 36254276)
4. Paulin D, Huet A, Khanamyrian L, Xue Z. Desminopathies in muscle disease. J Pathol 2004;204:418-27. (Pubitemid 39468153)
5. Morrison LE, Whittaker RJ, Klepper RE, Wawrousek EF, Glembotski CC. Roles for alphaB-crystallin and HSPB2 in protecting the myocardium from ischemia-reperfusion-induced damage in a KO mouse model. Am J Physiol Heart Circ Physiol 2004;286:H847-55.
6. Ray PS, Martin JL, Swanson EA, Otani H, Dillmann W, Das DK. Transgene overexpression of alphaB crystallin confers simultaneous protection against cardiomyocyte apoptosis and necrosis during myocardial ischemia and reperfusion. FASEB J 2001;15:393-402. (Pubitemid 32141431)
7. Ousman SS, Tomooka BH, van Noort JM, et al. Protective and therapeutic role for alphaB-crystallin in autoimmune demyelination. Nature 2007;448:474-9. (Pubitemid 47123511)
8. Claycomb WC, Lanson NA, Stallworth BS, et al. HL-1 cells: a cardiac muscle cell line that contracts and retains phenotypic characteristics of the adult cardiomyocyte. Proc Natl Acad Sci USA 1998;95:2979-84. (Pubitemid 28135840)
9. González-Juanatey JR, Piñeiro R, Iglesias MJ, et al. GH prevents apoptosis in cardiomyocytes cultured in vitro through a calcineurin-dependent mechanism. J Endocrinol 2004;180:325-35. (Pubitemid 38312614)
10. Gao J, Chang Chua C, Chen Z, et al. Resistin, an adipocytokine, offers protection against acute myocardial infarction. J Mol Cell Cardiol 2007;43:601-9.
11. Barba I, Chavarria L, Ruiz-Meana M, Mirabet M, Agulló E, Garcia-Dorado D. Effect of intracellular lipid droplets on cytosolic Ca2+ and cell death during ischaemia-reperfusion injury in cardiomyocytes. J Physiol 2009;587:1331-41.
12. Ades EW, Candal FJ, Swerlick RA, at al. HMEC-1: establishment of an immortalized human microvascular endothelial cell line. J Invest Dermatol 1992;99:683-90. (Pubitemid 23002027)
13. Lee WH, Kang S, Vlachos PP, Lee YW. A novel in vitro ischemia/reperfusion injury model. Arch Pharm Res 2009;32: 421-9.
14. True AL, Rahman A, Malik AB. Activation of NF-kappaB induced by H2O2 and TNF-alpha and its effects on ICAM-1 expression in endothelial cells. Am J Physiol Lung Cell Mol Physiol 2000;279:L302-11.
15. Eum SY, Lee YW, Hennig B, Toborek M. VEGF regulates PCB 104-mediated stimulation of permeability and transmigration of breast cancer cells in human microvascular endothelial cells. Exp Cell Res 2004;296:231-44. (Pubitemid 38624644)
16. Hu S, Huang M, Li Z, et al. MicroRNA-210 as a novel therapy for treatment of ischemic heart disease. Circulation 2010; 122(Suppl):124-31.
17. Lin KY, Ito A, Asagami T, et al. Impaired nitric oxide synthase pathway in diabetes mellitus: role of asymmetric dimethylarginine and dimethylarginine dimethylaminohydrolase. Circulation 2002;106:987-92. (Pubitemid 34925335)
18. Shang L, Ananthakrishnan R, Li Q, et al. RAGE modulates hypoxia/reoxygenation injury in adult murine cardiomyocytes through JNK and GSK-3beta signaling pathways. PLoS One 2010;5:e10092.
19. Davidson SM, Duchen MR. Endothelial mitochondria: contributing to vascular function and disease. Circ Res 2007;100: 1128-41. (Pubitemid 46684126)
20. Benjamin IJ, Guo Y, Srinivasan S, et al. CRYAB and HSPB2 deficiency alters cardiac metabolism and paradoxically confers protection against myocardial ischemia in aging mice. Am J Physiol Heart Circ Physiol 2007;293:H3201-9.
21. Wollert KC, Meyer GP, Lotz J, et al. Intracoronary autologous bone-marrow cell transfer after myocardial infarction: the BOOST randomized controlled clinical trial. Lancet 2004; 364:141-8. (Pubitemid 38891685)
22. Schachinger V, Erbs S, Elsasser A, et al. Intracoronary bone marrow-derived progenitor cells in acute myocardial infarction. N Engl J Med 2006;355:1210-21. (Pubitemid 44427445)
23. Cobb BA, Petrash JM. Characterization of alpha-crystallin-plasma membrane binding. J Biol Chem 2000;275:6664-72.
24. Kozawa O, Matsuno H, Niwa M, Hatakeyama D, Kato K, Uematsu T. AlphaB-crystallin, a low-molecular-weight heat shock protein, acts as a regulator of platelet function. Cell Stress Chaperones 2001;6:21-8. (Pubitemid 32275325)
25. Nagaraj RH, Oya-Ito T, Bhat M, Liu B. Dicarbonyl stress and apoptosis of vascular cells: prevention by alphaB-crystallin. Ann NY Acad Sci 2005;1043:158-65. (Pubitemid 41123902)
26. Liu B, Bhat M, Nagaraj RH. AlphaB-crystallin inhibits glucose-induced apoptosis in vascular endothelial cells. Biochem Biophys Res Commun 2004;321:254-8. (Pubitemid 39055632)
27. Dimberg A, Rylova S, Dieterich LC, et al. AlphaB-crystallin promotes tumor angiogenesis by increasing vascular survival during tube morphogenesis. Blood 2008;111:2015-23. (Pubitemid 351451512)
28. Kamradt MC, Chen F, Cryns VL. The small heat shock protein alpha B-crystallin negatively regulates cytochrome c-and caspase-8-dependent activation of caspase-3 by inhibiting its autoproteolytic maturation. J Biol Chem 2001;276: 16059-63.
29. Golenhofen N, Ness W, Wawrousek EF, Drenckhahn D. Expression and induction of the stress protein alpha-B-crystallin in vascular endothelial cells. Histochem Cell Biol 2002;117:203-9. (Pubitemid 34253324)
30. Clements R, Sodha N, Feng J, et al. Phosphorylation and translocation of heat shock protein 27 and αβ-crystallin in human myocardium after cardioplegia and cardiopulmonary bypass. J Thorac Cardiovasc Surg 2007;134:1461-70.