FOXO1 impairs whereas statin protects endothelial function in diabetes through reciprocal regulation of Krüppel-like factor 2

Cardiovascular Research

Volumn 97, Issue 1, 2013, Pages 143-152

  Lee, Hae Young ^a,b   Youn, Seock Won ^a   Cho, Hyun Jai ^a,b   Kwon, Yoo Wook ^a   Lee, Sae Won ^a   Kim, Sung Jin ^a   Park, Young Bae ^b   Oh, Byung Hee ^b   Kim, Hyo Soo ^a,b  

^a National Research Laboratory for Cardiovascular Stem Cell Niche   (South Korea)

^b Seoul National University Hospital   (South Korea)

Author keywords

Diabetes; FOXO1; Kr ppel like factor 2; Statin

Indexed keywords

ALPHA TUBULIN; ATORVASTATIN; ENDOTHELIAL NITRIC OXIDE SYNTHASE; GLUCOSE; KRUPPEL LIKE FACTOR 2; MESSENGER RNA; TRANSCRIPTION FACTOR FKHR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL NUCLEUS; CELLULAR DISTRIBUTION; CHROMATIN IMMUNOPRECIPITATION; CYTOPLASM; ENDOTHELIAL DYSFUNCTION; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; IN VIVO GENE TRANSFER; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; UMBILICAL VEIN ENDOTHELIAL CELL; VASCULAR ENDOTHELIUM; VASODILATATION; VIRAL GENE DELIVERY SYSTEM;

ANIMALS; BASE SEQUENCE; BINDING SITES; BLOOD GLUCOSE; CELLS, CULTURED; CHROMATIN IMMUNOPRECIPITATION; CYTOPROTECTION; DIABETES MELLITUS, TYPE 2; DIABETIC ANGIOPATHIES; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; ENDOTHELIUM, VASCULAR; FORKHEAD TRANSCRIPTION FACTORS; GENE EXPRESSION REGULATION; HEPTANOIC ACIDS; HUMAN UMBILICAL VEIN ENDOTHELIAL CELLS; HUMANS; HYDROXYMETHYLGLUTARYL-COA REDUCTASE INHIBITORS; KRUPPEL-LIKE TRANSCRIPTION FACTORS; MALE; MEVALONIC ACID; MOLECULAR SEQUENCE DATA; NERVE TISSUE PROTEINS; NITRIC OXIDE SYNTHASE TYPE III; PHOSPHORYLATION; PROMOTER REGIONS, GENETIC; PYRROLES; RATS; RATS, INBRED OLETF; RNA INTERFERENCE; TIME FACTORS; TRANSFECTION; VASODILATION; VASODILATOR AGENTS;

EID: 84871797076     PISSN: 00086363     EISSN: 17553245     Source Type: Journal    
DOI: 10.1093/cvr/cvs283     Document Type: Article

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