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Volumn 23, Issue 1, 2013, Pages 20-28

Variants in the 15q25 gene cluster are associated with risk for schizophrenia and bipolar disorder

Author keywords

15q25 gene cluster; bipolar disorder; CHRNA5; nicotine dependence; schizophrenia

Indexed keywords

ADULT; AFRICAN AMERICAN; ARTICLE; AUTOPSY; BIPOLAR DISORDER; CHROMOSOME 15Q; EUROPEAN AMERICAN; FEMALE; GENE EXPRESSION; GENETIC ASSOCIATION; GENETIC RISK; GENETIC VARIABILITY; GENOTYPE; HUMAN; HUMAN TISSUE; MAJOR CLINICAL STUDY; MALE; NEGATIVE SYNDROME; PERIPHERAL BLOOD MONONUCLEAR CELL; PRIORITY JOURNAL; SCHIZOPHRENIA; SINGLE NUCLEOTIDE POLYMORPHISM;

EID: 84871796589     PISSN: 09558829     EISSN: 14735873     Source Type: Journal    
DOI: 10.1097/YPG.0b013e32835bd5f1     Document Type: Article
Times cited : (35)

References (56)
  • 1
    • 73049084248 scopus 로고    scopus 로고
    • Convergence of genetic findings for nicotine dependence and smoking related diseases with chromosome 15q24-25
    • Bierut LJ (2010). Convergence of genetic findings for nicotine dependence and smoking related diseases with chromosome 15q24-25. Trends Pharmacol Sci 31:46-51.
    • (2010) Trends Pharmacol Sci , vol.31 , pp. 46-51
    • Bierut, L.J.1
  • 3
    • 0002616202 scopus 로고    scopus 로고
    • The common genetic liability between schizophrenia and bipolar disorder: A review
    • Bramon E, Sham PC (2001). The common genetic liability between schizophrenia and bipolar disorder: a review. Curr Psychiatry Rep 3:332-337.
    • (2001) Curr Psychiatry Rep , vol.3 , pp. 332-337
    • Bramon, E.1    Sham, P.C.2
  • 4
    • 0031977231 scopus 로고    scopus 로고
    • Substance abuse in schizophrenia: A review
    • Buckley PF (1998). Substance abuse in schizophrenia: a review. J Clin Psychiatry 59:26-30.
    • (1998) J Clin Psychiatry , vol.59 , pp. 26-30
    • Buckley, P.F.1
  • 5
    • 36549065299 scopus 로고    scopus 로고
    • The prevalence and significance of substance use disorders in bipolar type i and II disorder
    • Cerullo MA, Strakowski SM (2007). The prevalence and significance of substance use disorders in bipolar type I and II disorder. Subst Abuse Treat Prev Policy 2:29.
    • (2007) Subst Abuse Treat Prev Policy , vol.2 , pp. 29
    • Cerullo, M.A.1    Strakowski, S.M.2
  • 6
    • 84862870071 scopus 로고    scopus 로고
    • Nicotine dependence and comorbid psychiatric disorders: Examination of specific genetic variants in the CHRNA5-A3-B4 nicotinic receptor genes
    • Chen LS, Xian H, Grucza RA, Saccone NL,Wang JC, Johnson EO, et al. (2012). Nicotine dependence and comorbid psychiatric disorders: examination of specific genetic variants in the CHRNA5-A3-B4 nicotinic receptor genes. Drug Alcohol Depend 123:S42-S51, http://dx.doi.org.proxy.library.vcu.edu/ 10.1016/j.drugalcdep.2012.01.014.
    • (2012) Drug Alcohol Depend , vol.123
    • Chen, L.S.1    Xian, H.2    Grucza, R.A.3    Saccone Nlwang, J.C.4    Johnson, E.O.5
  • 7
    • 0031786335 scopus 로고    scopus 로고
    • Nicotine dependence and schizophrenia: Clinical phenomenon and laboratory findings
    • Dalack GW, Healy DJ, Meador-Woodruff JH (1998). Nicotine dependence and schizophrenia: clinical phenomenon and laboratory findings. Am J Psychiatry 155:1490-1501.
    • (1998) Am J Psychiatry , vol.155 , pp. 1490-1501
    • Dalack, G.W.1    Healy, D.J.2    Meador-Woodruff, J.H.3
  • 8
    • 20444463577 scopus 로고    scopus 로고
    • A meta-analysis of worldwide studies demonstrates an association between schizophrenia and tobacco smoking behaviors
    • De Leon J, Diaz FJ (2005). A meta-analysis of worldwide studies demonstrates an association between schizophrenia and tobacco smoking behaviors. Schizophr Res 76:135-157.
    • (2005) Schizophr Res , vol.76 , pp. 135-157
    • De Leon, J.1    Diaz, F.J.2
  • 9
    • 0028225793 scopus 로고
    • Patterns of substance abuse in schizophrenia: Nature and significance
    • DeQuardo JR, Carpenter CF, Tandon R (1994). Patterns of substance abuse in schizophrenia: nature and significance. J Psychiatr Res 28:267-275.
    • (1994) J Psychiatr Res , vol.28 , pp. 267-275
    • Dequardo, J.R.1    Carpenter, C.F.2    Tandon, R.3
  • 10
    • 61549091581 scopus 로고    scopus 로고
    • Tobacco smoking behaviors in bipolar disorder: A comparison of the general population, schizophrenia, and major depression
    • Diaz FJ, James D, Botts S, Maw L, Susce MT, de Leon J (2009). Tobacco smoking behaviors in bipolar disorder: a comparison of the general population, schizophrenia, and major depression. Bipolar Disord 11:154-165.
    • (2009) Bipolar Disord , vol.11 , pp. 154-165
    • Diaz, F.J.1    James, D.2    Botts, S.3    Maw, L.4    Susce, M.T.5    De Leon, J.6
  • 11
    • 41649094148 scopus 로고    scopus 로고
    • Likelihood-based association analysis for nuclear families and unrelated subjects with missing genotype data
    • Dudbridge F (2008). Likelihood-based association analysis for nuclear families and unrelated subjects with missing genotype data. Hum Hered 66:87-98.
    • (2008) Hum Hered , vol.66 , pp. 87-98
    • Dudbridge, F.1
  • 12
    • 78049443195 scopus 로고    scopus 로고
    • Nicotinic acetylcholine receptor genes on chromosome 15q25.1 are associated with nicotine and opioid dependence severity
    • Erlich PM, Hoffman SN, Rukstalis M, Han JJ, Chu X, Linda Kao WH, et al. (2010). Nicotinic acetylcholine receptor genes on chromosome 15q25.1 are associated with nicotine and opioid dependence severity. Hum Genet 128:491-499.
    • (2010) Hum Genet , vol.128 , pp. 491-499
    • Erlich, P.M.1    Hoffman, S.N.2    Rukstalis, M.3    Han, J.J.4    Chu, X.5    Linda Kao, W.H.6
  • 13
    • 26444474920 scopus 로고    scopus 로고
    • Relationship between a high-risk haplotype in the DTNBP1 (dysbindin) gene and clinical features of schizophrenia
    • Fanous AH, van den Oord EJ, Riley BP, Aggen SH, Neale MC, O'Neill FA, et al. (2005). Relationship between a high-risk haplotype in the DTNBP1 (dysbindin) gene and clinical features of schizophrenia. Am J Psychiatry 162:1824-1832.
    • (2005) Am J Psychiatry , vol.162 , pp. 1824-1832
    • Fanous, A.H.1    Van Den Oord, E.J.2    Riley, B.P.3    Aggen, S.H.4    Neale, M.C.5    O'Neill, F.A.6
  • 15
    • 0026800996 scopus 로고
    • Cigarette smoking in schizophrenia: Relationship to psychopathology and medication side effects
    • Goff DC, Henderson DC, Amico E (1992). Cigarette smoking in schizophrenia: relationship to psychopathology and medication side effects. Am J Psychiatry 149:1189-1194.
    • (1992) Am J Psychiatry , vol.149 , pp. 1189-1194
    • Goff, D.C.1    Henderson, D.C.2    Amico, E.3
  • 18
    • 0029088632 scopus 로고
    • Level of functioning, severity of illness, and smoking status among chronic psychiatric patients
    • Hall RG, Duhamel M, McClanahan R, Miles G, Nason C, Rosen S, et al. (1995). Level of functioning, severity of illness, and smoking status among chronic psychiatric patients. J Nerv Ment Dis 183:468-471.
    • (1995) J Nerv Ment Dis , vol.183 , pp. 468-471
    • Hall, R.G.1    Duhamel, M.2    McClanahan, R.3    Miles, G.4    Nason, C.5    Rosen, S.6
  • 20
    • 17744366803 scopus 로고    scopus 로고
    • Co-morbidity of smoking in patients with psychiatric and substance use disorders
    • Kalman D, Morrissette SB, George TP (2005). Co-morbidity of smoking in patients with psychiatric and substance use disorders. Am J Addict 14:106-123.
    • (2005) Am J Addict , vol.14 , pp. 106-123
    • Kalman, D.1    Morrissette, S.B.2    George, T.P.3
  • 21
    • 0029983060 scopus 로고    scopus 로고
    • Irish study on high-density schizophrenia families: Field methods and power to detect linkage
    • Kendler KS, O'Neill FA, Burke J, Murphy B, Duke F, Straub RE, et al. (1996). Irish study on high-density schizophrenia families: field methods and power to detect linkage. Am J Med Genet 67:179-190.
    • (1996) Am J Med Genet , vol.67 , pp. 179-190
    • Kendler, K.S.1    O'Neill, F.A.2    Burke, J.3    Murphy, B.4    Duke, F.5    Straub, R.E.6
  • 22
    • 0141567810 scopus 로고    scopus 로고
    • The structure of genetic and environmental risk factors for common psychiatric and substance use disorders in men and women
    • Kendler KS, Prescott CA, Myers J, Neale MC (2003). The structure of genetic and environmental risk factors for common psychiatric and substance use disorders in men and women. Arch Gen Psychiatry 60:929-937.
    • (2003) Arch Gen Psychiatry , vol.60 , pp. 929-937
    • Kendler, K.S.1    Prescott, C.A.2    Myers, J.3    Neale, M.C.4
  • 24
    • 36448982527 scopus 로고    scopus 로고
    • Smoking, genetics, and schizophrenia: Evidence for self medication
    • Leonard S, Mexal S, Freedman R (2007). Smoking, genetics, and schizophrenia: evidence for self medication. J Dual Diagn 3:43-59.
    • (2007) J Dual Diagn , vol.3 , pp. 43-59
    • Leonard, S.1    Mexal, S.2    Freedman, R.3
  • 25
  • 26
    • 33645559825 scopus 로고    scopus 로고
    • The genetics of nicotine dependence
    • Li MD (2006). The genetics of nicotine dependence. Curr Psychiatry Rep 8:158-164.
    • (2006) Curr Psychiatry Rep , vol.8 , pp. 158-164
    • Li, M.D.1
  • 27
    • 77949869076 scopus 로고    scopus 로고
    • Association and interaction analysis of variants in CHRNA5/CHRNA3/CHRNB4 gene cluster with nicotine dependence in African and European Americans
    • Li MD, Xu Q, Lou XY, Payne TJ, Niu T, Ma JZ (2010). Association and interaction analysis of variants in CHRNA5/CHRNA3/CHRNB4 gene cluster with nicotine dependence in African and European Americans. Am J Med Genet B Neuropsychiatr Genet 153B:745-756.
    • (2010) Am J Med Genet B Neuropsychiatr Genet , vol.153 , pp. 745-756
    • Li, M.D.1    Xu, Q.2    Lou, X.Y.3    Payne, T.J.4    Niu, T.5    Ma, J.Z.6
  • 28
    • 58149464318 scopus 로고    scopus 로고
    • Common genetic determinants of schizophrenia and bipolar disorder in Swedish families: A population-based study
    • Lichtenstein P, Yip BH, Bjork C, Pawitan Y, Cannon TD, Sullivan PF, et al. (2009). Common genetic determinants of schizophrenia and bipolar disorder in Swedish families: a population-based study. Lancet 373:234-239.
    • (2009) Lancet , vol.373 , pp. 234-239
    • Lichtenstein, P.1    Yip, B.H.2    Bjork, C.3    Pawitan, Y.4    Cannon, T.D.5    Sullivan, P.F.6
  • 29
    • 77951766653 scopus 로고    scopus 로고
    • Association between a 15q25 gene variant, smoking quantity and tobaccorelated cancers among 17000 individuals
    • Lips EH, Gaborieau V, McKay JD, Chabrier A, Hung RJ, Boffetta P, et al. (2010). Association between a 15q25 gene variant, smoking quantity and tobaccorelated cancers among 17000 individuals. Int J Epidemiol 39:563-577.
    • (2010) Int J Epidemiol , vol.39 , pp. 563-577
    • Lips, E.H.1    Gaborieau, V.2    McKay, J.D.3    Chabrier, A.4    Hung, R.J.5    Boffetta, P.6
  • 30
    • 77951751034 scopus 로고    scopus 로고
    • Meta-analysis and imputation refines the association of 15q25 with smoking quantity
    • Liu JZ, Tozzi F, Waterworth DM, Pillai SG, Muglia P, Middleton L, et al. (2010). Meta-analysis and imputation refines the association of 15q25 with smoking quantity. Nat Genet 42:436-440.
    • (2010) Nat Genet , vol.42 , pp. 436-440
    • Liu, J.Z.1    Tozzi, F.2    Waterworth, D.M.3    Pillai, S.G.4    Muglia, P.5    Middleton, L.6
  • 32
    • 77952714079 scopus 로고    scopus 로고
    • GWAMA software for genome-wide association meta-analysis
    • Magi R, Morris AP (2010). GWAMA: software for genome-wide association meta-analysis. BMC Bioinformatics 11:288.
    • (2010) BMC Bioinformatics , vol.11 , pp. 288
    • Magi, R.1    Morris, A.P.2
  • 34
    • 1842539516 scopus 로고    scopus 로고
    • A simple correction for multiple testing for SNPs in linkage disequilibrium with each other
    • Nyholt DR (2004). A simple correction for multiple testing for SNPs in linkage disequilibrium with each other. Am J Hum Genet 74:765-769.
    • (2004) Am J Hum Genet , vol.74 , pp. 765-769
    • Nyholt, D.R.1
  • 37
    • 34548292504 scopus 로고    scopus 로고
    • PLINK: A toolset for whole-genome association and populationbased linkage analysis
    • Purcell S, Neale B, Todd-Brown K, Thomas L, Ferreira MAR, Bender D, et al. (2007). PLINK: a toolset for whole-genome association and populationbased linkage analysis. Am J Hum Genet 81:559-575.
    • (2007) Am J Hum Genet , vol.81 , pp. 559-575
    • Purcell, S.1    Neale, B.2    Todd-Brown, K.3    Thomas, L.4    Mar, F.5    Bender, D.6
  • 38
    • 71649113424 scopus 로고    scopus 로고
    • The dystrobrevin binding protein 1 (DTNBP1) gene is associated with schizophrenia in the Irish Case Control Study of Schizophrenia (ICCSS) sample
    • Riley B, Kuo PH, Maher BS, Fanous AH, Sun J, Wormley B, et al. (2009). The dystrobrevin binding protein 1 (DTNBP1) gene is associated with schizophrenia in the Irish Case Control Study of Schizophrenia (ICCSS) sample. Schizophr Res 115:245-253.
    • (2009) Schizophr Res , vol.115 , pp. 245-253
    • Riley, B.1    Kuo, P.H.2    Maher, B.S.3    Fanous, A.H.4    Sun, J.5    Wormley, B.6
  • 39
    • 66649097962 scopus 로고    scopus 로고
    • Multiple distinct risk loci for nicotine dependence identified by dense coverage of the complete family of nicotinic receptor subunit (CHRN) genes
    • Saccone NL, Saccone SF, Hinrichs AL, Stitzel JA, Duan W, Pergadia ML, et al. (2009). Multiple distinct risk loci for nicotine dependence identified by dense coverage of the complete family of nicotinic receptor subunit (CHRN) genes. Am J Med Genet B Neuropsychiatr Genet 150B:453-466.
    • (2009) Am J Med Genet B Neuropsychiatr Genet , vol.150 , pp. 453-466
    • Saccone, N.L.1    Saccone, S.F.2    Hinrichs, A.L.3    Stitzel, J.A.4    Duan, W.5    Pergadia, M.L.6
  • 40
    • 33644974019 scopus 로고    scopus 로고
    • A fast and flexible statistical model for large-scale population genotype data: Applications to inferring missing genotypes and haplotypic phase
    • Scheet P, Stephens M (2006). A fast and flexible statistical model for large-scale population genotype data: applications to inferring missing genotypes and haplotypic phase. Am J Hum Genet 78:629-644.
    • (2006) Am J Hum Genet , vol.78 , pp. 629-644
    • Scheet, P.1    Stephens, M.2
  • 41
    • 45449091369 scopus 로고    scopus 로고
    • Shared gene expression alterations in schizophrenia and bipolar disorder
    • Shao L, Vawter MP (2008). Shared gene expression alterations in schizophrenia and bipolar disorder. Biol Psychiatry 64:89-97.
    • (2008) Biol Psychiatry , vol.64 , pp. 89-97
    • Shao, L.1    Vawter, M.P.2
  • 42
    • 77954761157 scopus 로고    scopus 로고
    • Variation in nicotinic acetylcholine receptor genes is associated with multiple substance dependence phenotypes
    • Sherva R, Kranzler HR, Yu Y, Logue MW, Poling J, Arias AJ, et al. (2010). Variation in nicotinic acetylcholine receptor genes is associated with multiple substance dependence phenotypes. Neuropsychopharmacology 35:1921- 1931.
    • (2010) Neuropsychopharmacology , vol.35 , pp. 1921-1931
    • Sherva, R.1    Kranzler, H.R.2    Yu, Y.3    Logue, M.W.4    Poling, J.5    Arias, A.J.6
  • 43
    • 0028061488 scopus 로고
    • Substance abuse in psychotic disorders: Associations with affective syndromes
    • Strakowski SM, Tohen M, Flaum M, Amador X (1994). Substance abuse in psychotic disorders: associations with affective syndromes. Schizophr Res 14:73-81.
    • (1994) Schizophr Res , vol.14 , pp. 73-81
    • Strakowski, S.M.1    Tohen, M.2    Flaum, M.3    Amador, X.4
  • 44
    • 0344305525 scopus 로고    scopus 로고
    • Schizophrenia as a complex trait: Evidence from a meta analysis of twin studies
    • Sullivan PF, Kendler KS, Neale MC (2003). Schizophrenia as a complex trait: evidence from a meta analysis of twin studies. Arch Gen Psychiatry 60:1187-1192.
    • (2003) Arch Gen Psychiatry , vol.60 , pp. 1187-1192
    • Sullivan, P.F.1    Kendler, K.S.2    Neale, M.C.3
  • 46
    • 26444499116 scopus 로고    scopus 로고
    • Cigarette smoking topography in smokers with schizophrenia and matched non-psychiatric controls
    • Tidey JW, Rohsenow DJ, Kaplan GB, Swift RM (2005). Cigarette smoking topography in smokers with schizophrenia and matched non-psychiatric controls. Drug Alcohol Depend 80:259-265.
    • (2005) Drug Alcohol Depend , vol.80 , pp. 259-265
    • Tidey, J.W.1    Rohsenow, D.J.2    Kaplan, G.B.3    Swift, R.M.4
  • 47
    • 77951711343 scopus 로고    scopus 로고
    • Tobacco and genetics (tag) consortium Genome-wide meta-analyses identify multiple loci associated with smoking behavior
    • Tobacco and Genetics (TAG) Consortium (2010). Genome-wide meta-analyses identify multiple loci associated with smoking behavior. Nat Genet 42:441-447.
    • (2010) Nat Genet , vol.42 , pp. 441-447
  • 48
    • 17344367165 scopus 로고    scopus 로고
    • Cooccurrence of abuse of different drugs in men: The role of drug-specific and shared vulnerabilities
    • Tsuang MT, Lyons MJ, Meyer JM, Doyle T, Eisen SA, Goldberg J, et al. (1998). Cooccurrence of abuse of different drugs in men: the role of drug-specific and shared vulnerabilities. Arch Gen Psychiatry 55:967-972.
    • (1998) Arch Gen Psychiatry , vol.55 , pp. 967-972
    • Tsuang, M.T.1    Lyons, M.J.2    Meyer, J.M.3    Doyle, T.4    Eisen, S.A.5    Goldberg, J.6
  • 49
    • 0345097499 scopus 로고    scopus 로고
    • Smoking among psychiatric outpatients: Relationship to substance use, diagnosis, and illness severity
    • Vanable PA, Carey MP, Carey KB, Maisto SA (2003). Smoking among psychiatric outpatients: relationship to substance use, diagnosis, and illness severity. Psychol Addict Behav 17:259-265.
    • (2003) Psychol Addict Behav , vol.17 , pp. 259-265
    • Vanable, P.A.1    Carey, M.P.2    Carey, K.B.3    Maisto, S.A.4
  • 50
    • 68049090045 scopus 로고    scopus 로고
    • Risk for nicotine dependence and lung cancer is conferred by mRNA expression levels and amino acid change in CHRNA5
    • Wang JC, Cruchaga C, Saccone NL, Bertelsen S, Liu P, Budde JP, et al. (2009). Risk for nicotine dependence and lung cancer is conferred by mRNA expression levels and amino acid change in CHRNA5. Hum Mol Genet 18:3125-3135.
    • (2009) Hum Mol Genet , vol.18 , pp. 3125-3135
    • Wang, J.C.1    Cruchaga, C.2    Saccone, N.L.3    Bertelsen, S.4    Liu, P.5    Budde, J.P.6
  • 51
    • 82455172054 scopus 로고    scopus 로고
    • Association of the CHRNA5-A3- B4 gene cluster with heaviness of smoking: A meta-analysis
    • Ware JJ, van den Bree MB, Munafo MR (2011). Association of the CHRNA5-A3- B4 gene cluster with heaviness of smoking: a meta-analysis. Nicotine Tob Res 13:1167-1175.
    • (2011) Nicotine Tob Res , vol.13 , pp. 1167-1175
    • Ware, J.J.1    Van Den Bree, M.B.2    Munafo, M.R.3
  • 52
  • 53
    • 76649095277 scopus 로고    scopus 로고
    • Why do patients with schizophrenia smoke?
    • Winterer G (2010). Why do patients with schizophrenia smoke? Curr Opin Psychiatry 23:112-119.
    • (2010) Curr Opin Psychiatry , vol.23 , pp. 112-119
    • Winterer, G.1
  • 54
    • 78851471766 scopus 로고    scopus 로고
    • Risk gene variants for nicotine dependence in the CHRNA5-CHRNA3- CHRNB4 cluster are associated with cognitive performance
    • Winterer G, Mittelstrass K, Giegling I, Lamina C, Fehr C, Brenner H, et al. (2010). Risk gene variants for nicotine dependence in the CHRNA5-CHRNA3- CHRNB4 cluster are associated with cognitive performance. Am J Med Genet B Neuropsychiatr Genet 153B:1448-1458.
    • (2010) Am J Med Genet B Neuropsychiatr Genet , vol.153 , pp. 1448-1458
    • Winterer, G.1    Mittelstrass, K.2    Giegling, I.3    Lamina, C.4    Fehr, C.5    Brenner, H.6
  • 56
    • 78651322488 scopus 로고    scopus 로고
    • Variation in the nicotinic acetylcholine receptor gene cluster CHRNA5-CHRNA3-CHRNB4 and its interaction with recent tobacco use influence cognitive flexibility
    • Zhang H, Kranzler HR, Poling J, Gelernter J (2010). Variation in the nicotinic acetylcholine receptor gene cluster CHRNA5-CHRNA3-CHRNB4 and its interaction with recent tobacco use influence cognitive flexibility. Neuropsychopharmacology 35:2211-2224.
    • (2010) Neuropsychopharmacology , vol.35 , pp. 2211-2224
    • Zhang, H.1    Kranzler, H.R.2    Poling, J.3    Gelernter, J.4


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