Myelin is dependent on the Charcot-Marie-Tooth Type 4H disease culprit protein FRABIN/FGD4 in Schwann cells

Brain

Volumn 135, Issue 12, 2012, Pages 3567-3583

  Horn, Michael ^a   Baumann, Reto ^a   Pereira, Jorge A ^a   Sidiropoulos, Páris N M ^a   Somandin, Christian ^a   Welzl, Hans ^b   Stendel, Claudia ^a,e   Lühmann, Tessa ^a,c   Wessig, Carsten ^c   Toyka, Klaus V ^c   Relvas, João B ^a,d   Senderek, Jan ^a,f   Suter, Ueli ^a  

^a ETH ZURICH   (Switzerland)

^b UNIVERSITY OF ZURICH   (Switzerland)

^c UNIVERSITY OF WÜRZBURG   (Germany)

^d UNIVERSITY OF PORTO   (Portugal)

^e RWTH AACHEN UNIVERSITY   (Germany)

^f LUDWIG MAXIMILIANS UNIVERSITY   (Germany)

Author keywords

CharcotMarieTooth disease; Frabin Fgd4; hereditary motor and sensory neuropathy; myelination; Rho GTPase Cdc42

Indexed keywords

CRE RECOMBINASE; FGD4 PROTEIN; FRABIN PROTEIN; GUANINE NUCLEOTIDE EXCHANGE FACTOR; MYELIN; PROTEIN CDC42; UNCLASSIFIED DRUG;

ALLELE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN ELECTROPHYSIOLOGY; CELL TYPE; CHARCOT MARIE TOOTH TYPE 4H DISEASE; CONTROLLED STUDY; DEMYELINATION; ENDOCYTOSIS; GENE DELETION; GENE DISRUPTION; GENE EXPRESSION; GENE FREQUENCY; GENE SEQUENCE; HEREDITARY MOTOR SENSORY NEUROPATHY; LOXP SITE; MOUSE; MYELIN DEFICIENCY; MYELINATION; NERVE CELL; NERVE FIBER; NONHUMAN; PATHOPHYSIOLOGY; PERIPHERAL NERVE; PERIPHERAL NERVOUS SYSTEM; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; SCHWANN CELL;

EID: 84871796541     PISSN: 00068950     EISSN: 14602156     Source Type: Journal    
DOI: 10.1093/brain/aws275     Document Type: Article

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