Modification of pharmacokinetic and abuse-related effects of cocaine by human-derived cocaine hydrolase in monkeys

Addiction Biology

Volumn 18, Issue 1, 2013, Pages 30-39

  Schindler, Charles W ^a   Justinova, Zuzana ^a,b   Lafleur, David ^c   Woods, Doug ^d   Roschke, Viktor ^c   Hallak, Hussein ^e   Sklair Tavron, Liora ^e   Redhi, Godfrey H ^a   Yasar, Sevil ^f   Bergman, Jack ^g   Goldberg, Steven R ^a  

^a NATIONAL INSTITUTE ON DRUG ABUSE   (United States)

^b UNIVERSITY OF MARYLAND SCHOOL OF MEDICINE   (United States)

^c Zyngenia Inc   (United States)

^d Teva Pharmaceutical Industries Ltd ^*  (United States)

^e TEVA PHARMACEUTICALS   (Israel)

^f JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^g HARVARD MEDICAL SCHOOL   (United States)

Author keywords

Cocaine; discrimination; hydrolase; reinstatement; self administration; squirrel monkeys

Indexed keywords

ALBUMIN COCAINE HYDROLASE; CHOLINESTERASE; COCAINE; ECGONINE METHYL ESTER; METHAMPHETAMINE; RECOMBINANT ENZYME; UNCLASSIFIED DRUG;

ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ARTICLE; CATALYSIS; CONTROLLED STUDY; DOSE RESPONSE; DRUG BLOOD LEVEL; DRUG EFFECT; DRUG HALF LIFE; DRUG SELF ADMINISTRATION; ENZYME ACTIVITY; GENE MUTATION; MALE; NONHUMAN; PRIORITY JOURNAL; REINFORCEMENT; SQUIRREL MONKEY;

EID: 84871772754     PISSN: 13556215     EISSN: 13691600     Source Type: Journal    
DOI: 10.1111/j.1369-1600.2011.00424.x     Document Type: Article

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