메뉴 건너뛰기




Volumn 75, Issue , 2013, Pages 25-32

Application of an efficient strategy for discovery and purification of bioactive compounds from Chinese herbal medicines, a case study on the Puerariae thomsonii Flos

Author keywords

Bioassay guided fractionation; HPLC ESI Q TOF MS; HSCCC; Puerariae thomsonii Flos; Tectorigenin

Indexed keywords

6 HYDROXYGENISTEIN 6,7 DI O GLUCOSIDE; ANTINEOPLASTIC AGENT; GENISTEIN 7 O GLUCOSIDE; PUERARIA EXTRACT; PUERARIAE THOMSONII FLOS EXTRACT; TECTORIGENIN; TECTORIGENIN 7O [BETA DEXTRO XYLOPYRANOSYL(1-6)BETA DEXTRO GLUCOPYRANOSIDE; UNCLASSIFIED DRUG;

EID: 84871752042     PISSN: 07317085     EISSN: 1873264X     Source Type: Journal    
DOI: 10.1016/j.jpba.2012.11.009     Document Type: Article
Times cited : (18)

References (30)
  • 1
    • 52049109838 scopus 로고    scopus 로고
    • Natural products in drug discovery
    • Harvey A.L. Natural products in drug discovery. Drug Discov. Today 2008, 13:894-901.
    • (2008) Drug Discov. Today , vol.13 , pp. 894-901
    • Harvey, A.L.1
  • 2
    • 44249098800 scopus 로고    scopus 로고
    • Natural products to drugs: natural product-derived compounds in clinical trials
    • Butler M.S. Natural products to drugs: natural product-derived compounds in clinical trials. Nat. Prod. Rep. 2008, 25:475-516.
    • (2008) Nat. Prod. Rep. , vol.25 , pp. 475-516
    • Butler, M.S.1
  • 3
    • 39149084998 scopus 로고    scopus 로고
    • Analysis of Chinese herbal medicines with holistic approaches and integrated evaluation models
    • Li P., Qi L.W., Liu E.H., Zhou J.L., Wen X.D. Analysis of Chinese herbal medicines with holistic approaches and integrated evaluation models. Trends Anal. Chem. 2008, 27:66-77.
    • (2008) Trends Anal. Chem. , vol.27 , pp. 66-77
    • Li, P.1    Qi, L.W.2    Liu, E.H.3    Zhou, J.L.4    Wen, X.D.5
  • 5
    • 78651238811 scopus 로고    scopus 로고
    • Target-guided isolation and purification of antioxidants from Selaginella sinensis by offline coupling of DPPH-HPLC and HSCCC experiments
    • Zhang Y.P., Shi S.Y., Wang Y.X., Huang K.L. Target-guided isolation and purification of antioxidants from Selaginella sinensis by offline coupling of DPPH-HPLC and HSCCC experiments. J. Chromatogr. B 2011, 879:191-196.
    • (2011) J. Chromatogr. B , vol.879 , pp. 191-196
    • Zhang, Y.P.1    Shi, S.Y.2    Wang, Y.X.3    Huang, K.L.4
  • 6
    • 58349101317 scopus 로고    scopus 로고
    • Bioassay guided discovery of apoptosis inducers from gamboge by high-speed counter-current chromatography and high-pressure liquid chromatography/electrospray ionization quadrupole time-of-flight mass spectrometry
    • Han Q.B., Zhou Y., Feng C., Xu G., Huang S.X., Li S.L., Qiao C.F., Song J.Z., Chang D.C., Luo K.Q., Xu H.X. Bioassay guided discovery of apoptosis inducers from gamboge by high-speed counter-current chromatography and high-pressure liquid chromatography/electrospray ionization quadrupole time-of-flight mass spectrometry. J. Chromatogr. B 2009, 877:401-407.
    • (2009) J. Chromatogr. B , vol.877 , pp. 401-407
    • Han, Q.B.1    Zhou, Y.2    Feng, C.3    Xu, G.4    Huang, S.X.5    Li, S.L.6    Qiao, C.F.7    Song, J.Z.8    Chang, D.C.9    Luo, K.Q.10    Xu, H.X.11
  • 7
    • 84861178077 scopus 로고    scopus 로고
    • Bioassay-guided isolation of antioxidants from Astragalus altaicus by combination of chromatographic techniques
    • Yang C.Y., Yang Y., Aisa H.A., Xin X.L., Ma H.R., Abulimiti Y., Zhao Y.X. Bioassay-guided isolation of antioxidants from Astragalus altaicus by combination of chromatographic techniques. J. Sep. Sci. 2012, 35:977-983.
    • (2012) J. Sep. Sci. , vol.35 , pp. 977-983
    • Yang, C.Y.1    Yang, Y.2    Aisa, H.A.3    Xin, X.L.4    Ma, H.R.5    Abulimiti, Y.6    Zhao, Y.X.7
  • 8
    • 70349778830 scopus 로고    scopus 로고
    • Herbal medicine analysis by liquid chromatography/time-of-flight mass spectrometry
    • Zhou J.L., Qi L.W., Li P. Herbal medicine analysis by liquid chromatography/time-of-flight mass spectrometry. J. Chromatogr. A 2009, 1216:7582-7594.
    • (2009) J. Chromatogr. A , vol.1216 , pp. 7582-7594
    • Zhou, J.L.1    Qi, L.W.2    Li, P.3
  • 9
    • 80052818824 scopus 로고    scopus 로고
    • Ultra performance liquid chromatography coupled with quadrupole time-of-flight mass spectrometric procedure for qualitative and quantitative analyses of nortriterpenoids and lignans in the genus Schisandra
    • Zhou Y., Huang S.X., Pu J.X., Li J.R., Ding L.S., Chen D.F., Sun H.D., Xu H.X. Ultra performance liquid chromatography coupled with quadrupole time-of-flight mass spectrometric procedure for qualitative and quantitative analyses of nortriterpenoids and lignans in the genus Schisandra. J. Pharm. Biomed. Anal. 2011, 56:916-927.
    • (2011) J. Pharm. Biomed. Anal. , vol.56 , pp. 916-927
    • Zhou, Y.1    Huang, S.X.2    Pu, J.X.3    Li, J.R.4    Ding, L.S.5    Chen, D.F.6    Sun, H.D.7    Xu, H.X.8
  • 10
    • 79960975990 scopus 로고    scopus 로고
    • Ultrasonic/microwave assisted extraction and diagnostic ion filtering strategy by liquid chromatography-quadrupole time-of-flight mass spectrometry for rapid characterization of flavonoids in Spatholobus suberectus
    • Cheng X.L., Wan J.Y., Li P., Qi L.W. Ultrasonic/microwave assisted extraction and diagnostic ion filtering strategy by liquid chromatography-quadrupole time-of-flight mass spectrometry for rapid characterization of flavonoids in Spatholobus suberectus. J. Chromatogr. A 2011, 1218:5774-5786.
    • (2011) J. Chromatogr. A , vol.1218 , pp. 5774-5786
    • Cheng, X.L.1    Wan, J.Y.2    Li, P.3    Qi, L.W.4
  • 11
    • 33645831761 scopus 로고    scopus 로고
    • Developments in the application of counter-current chromatography to plant analysis
    • Marston A., Hostettmann K. Developments in the application of counter-current chromatography to plant analysis. J. Chromatogr. A 2006, 1112:181-194.
    • (2006) J. Chromatogr. A , vol.1112 , pp. 181-194
    • Marston, A.1    Hostettmann, K.2
  • 12
    • 34548317131 scopus 로고    scopus 로고
    • Isolation of ursolic acid from apple peels by high speed counter-current chromatography
    • Frighetto R.T., Welendorf R.M., Nigro E.N., Frighetto N., Siani A.C. Isolation of ursolic acid from apple peels by high speed counter-current chromatography. Food Chem. 2008, 106:767-771.
    • (2008) Food Chem. , vol.106 , pp. 767-771
    • Frighetto, R.T.1    Welendorf, R.M.2    Nigro, E.N.3    Frighetto, N.4    Siani, A.C.5
  • 13
    • 62249217188 scopus 로고    scopus 로고
    • Preparative separation of flavonoids in Adinandra nitida leaves by high-speedcounter-current chromatography and their effects on human epidermal carcinoma cancer cells
    • Yuan E.D., Liu B.G., Ning Z.X., Chen C.G. Preparative separation of flavonoids in Adinandra nitida leaves by high-speedcounter-current chromatography and their effects on human epidermal carcinoma cancer cells. Food Chem. 2009, 115:1158-1163.
    • (2009) Food Chem. , vol.115 , pp. 1158-1163
    • Yuan, E.D.1    Liu, B.G.2    Ning, Z.X.3    Chen, C.G.4
  • 14
    • 13644268562 scopus 로고    scopus 로고
    • Golden rules and pitfalls in selecting optim conditions for high-speed counter-current chromatography
    • Ito Y. Golden rules and pitfalls in selecting optim conditions for high-speed counter-current chromatography. J. Chromatogr. A 2005, 1065:145-168.
    • (2005) J. Chromatogr. A , vol.1065 , pp. 145-168
    • Ito, Y.1
  • 15
    • 33744944776 scopus 로고    scopus 로고
    • Estogenic effect of main components kakkalide and tectoridin of Puerariae Flos and their metabolites
    • Shin J.E., Bae E.A., Lee Y.C., Ma J.Y., Kim D.H. Estogenic effect of main components kakkalide and tectoridin of Puerariae Flos and their metabolites. Biol. Pharm. Bull. 2006, 29:1202-1206.
    • (2006) Biol. Pharm. Bull. , vol.29 , pp. 1202-1206
    • Shin, J.E.1    Bae, E.A.2    Lee, Y.C.3    Ma, J.Y.4    Kim, D.H.5
  • 16
    • 18244369994 scopus 로고    scopus 로고
    • Hepato-protective effect of tectoridin and tectorigenin on tert-butyl hyperoxide-induced liver injury
    • Lee H.U., Bae E.A., Kim D.H. Hepato-protective effect of tectoridin and tectorigenin on tert-butyl hyperoxide-induced liver injury. J. Pharmacol. Sci. 2005, 97:541-544.
    • (2005) J. Pharmacol. Sci. , vol.97 , pp. 541-544
    • Lee, H.U.1    Bae, E.A.2    Kim, D.H.3
  • 17
    • 79954422522 scopus 로고    scopus 로고
    • Kudzu root: traditional uses and potential medicinal benefits in diabetes and cardiovascular diseases
    • Wong K.H., Li G.Q., Li K.M., Razmovski N.V., Chan K. Kudzu root: traditional uses and potential medicinal benefits in diabetes and cardiovascular diseases. J. Ethnopharmacol. 2011, 134:584-607.
    • (2011) J. Ethnopharmacol. , vol.134 , pp. 584-607
    • Wong, K.H.1    Li, G.Q.2    Li, K.M.3    Razmovski, N.V.4    Chan, K.5
  • 18
    • 84862804856 scopus 로고    scopus 로고
    • In vitro evaluation of tectoridin, tectorigenin and tectorigenin sodium sulfonate on antioxidant properties
    • Han T., Cheng G., Liu Y., Yang H., Hu Y.T., Huang W. In vitro evaluation of tectoridin, tectorigenin and tectorigenin sodium sulfonate on antioxidant properties. Food Chem. Toxicol. 2012, 50:409-414.
    • (2012) Food Chem. Toxicol. , vol.50 , pp. 409-414
    • Han, T.1    Cheng, G.2    Liu, Y.3    Yang, H.4    Hu, Y.T.5    Huang, W.6
  • 19
    • 0035172712 scopus 로고    scopus 로고
    • Tectorigenin an isoflavonoids of Pueraria thunbergiana Benth., induces differentiation and apoptosis in human promyelocytic leukemia HL-60 cells
    • Lee K.T., Sohn I.C., Kim Y.K., Choi J.H., Choi J.W., Park H.J., Itoh Y., Miyamoto K. Tectorigenin an isoflavonoids of Pueraria thunbergiana Benth., induces differentiation and apoptosis in human promyelocytic leukemia HL-60 cells. Biol. Pharm. Bull. 2001, 24:1117-1121.
    • (2001) Biol. Pharm. Bull. , vol.24 , pp. 1117-1121
    • Lee, K.T.1    Sohn, I.C.2    Kim, Y.K.3    Choi, J.H.4    Choi, J.W.5    Park, H.J.6    Itoh, Y.7    Miyamoto, K.8
  • 20
    • 0032848459 scopus 로고    scopus 로고
    • Separation and purification of isoflavonoids from Pueraria lobata by high-speed counter-current chromatography
    • Cao X.L., Tian Y., Zhang T.Y., Li X., Ito Y. Separation and purification of isoflavonoids from Pueraria lobata by high-speed counter-current chromatography. J. Chromatogr. A 1999, 855:709-713.
    • (1999) J. Chromatogr. A , vol.855 , pp. 709-713
    • Cao, X.L.1    Tian, Y.2    Zhang, T.Y.3    Li, X.4    Ito, Y.5
  • 21
    • 77953614549 scopus 로고    scopus 로고
    • Simultaneous analysis of isoflavonoids and saponins in Pueraria flowers using HPLC coupled to an evaporative light scattering detector and isolation of a new isoflavonoids diglucoside
    • Niiho Y., Nakajima Y., Yamazaki T., Okamoto M., Tsuchihashi R., Kodera M., Kinjo J., Nohara T. Simultaneous analysis of isoflavonoids and saponins in Pueraria flowers using HPLC coupled to an evaporative light scattering detector and isolation of a new isoflavonoids diglucoside. J. Nat. Med. 2010, 64:313-320.
    • (2010) J. Nat. Med. , vol.64 , pp. 313-320
    • Niiho, Y.1    Nakajima, Y.2    Yamazaki, T.3    Okamoto, M.4    Tsuchihashi, R.5    Kodera, M.6    Kinjo, J.7    Nohara, T.8
  • 25
    • 84862777794 scopus 로고    scopus 로고
    • Systematic separation and purification of eighteen antioxidants from Pueraria lobata flower using HSCCC target-guided by DPPH-HPLC experiment
    • Shi S.Y., Ma Y.J., Zhang Y.P., Liu L.L., Liu Q., Peng M.J., Xiong X. Systematic separation and purification of eighteen antioxidants from Pueraria lobata flower using HSCCC target-guided by DPPH-HPLC experiment. Sep. Purif. Technol. 2012, 89:225-233.
    • (2012) Sep. Purif. Technol. , vol.89 , pp. 225-233
    • Shi, S.Y.1    Ma, Y.J.2    Zhang, Y.P.3    Liu, L.L.4    Liu, Q.5    Peng, M.J.6    Xiong, X.7
  • 28
    • 14044267753 scopus 로고    scopus 로고
    • Induction of cancer cell apoptosis by flavonoids is associated with their ability to inhibit fatty acid synthase activity
    • Brusslmans K., Vrolix R., Verhoeven G., Swinnen J. Induction of cancer cell apoptosis by flavonoids is associated with their ability to inhibit fatty acid synthase activity. J. Biol. Chem. 2005, 280:5636-5645.
    • (2005) J. Biol. Chem. , vol.280 , pp. 5636-5645
    • Brusslmans, K.1    Vrolix, R.2    Verhoeven, G.3    Swinnen, J.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.