-
1
-
-
0018630244
-
The natural history of breast cancer patients with brain metastases
-
498057 10.1002/1097-0142(197911)44:5<1913: AID-CNCR2820440554>3.0. CO;2-D 1:STN:280:DyaL3c%2FksVKhsw%3D%3D
-
DiStefano A, Yong YY, Hortobagyi GN, Blumenschein GR (1979) The natural history of breast cancer patients with brain metastases. Cancer 44:1913-1918
-
(1979)
Cancer
, vol.44
, pp. 1913-1918
-
-
Distefano, A.1
Yong, Y.Y.2
Hortobagyi, G.N.3
Blumenschein, G.R.4
-
2
-
-
0021050124
-
Central nervous system metastasis from breast carcinoma. Autopsy study
-
6640506 10.1002/1097-0142(19831215)52:12<2349: AID- CNCR2820521231>3.0.CO;2-B 1:STN:280:DyaL2c%2FlsV2qtg%3D%3D
-
Tsukada Y, Fouad A, Pickren JW, Lane WW (1983) Central nervous system metastasis from breast carcinoma. Autopsy study. Cancer 52:2349-2354
-
(1983)
Cancer
, vol.52
, pp. 2349-2354
-
-
Tsukada, Y.1
Fouad, A.2
Pickren, J.W.3
Lane, W.W.4
-
3
-
-
0023777633
-
Breast cancer: Metastatic patterns and their prognosis
-
3420442 10.1097/00007611-198809000-00011 1:STN:280:DyaL1czjs12nug%3D%3D
-
Patanaphan V, Salazar OM, Risco R (1988) Breast cancer: metastatic patterns and their prognosis. South Med J 81:1109-1112
-
(1988)
South Med J
, vol.81
, pp. 1109-1112
-
-
Patanaphan, V.1
Salazar, O.M.2
Risco, R.3
-
4
-
-
0020606340
-
Breast carcinoma: Pattern of metastasis at autopsy
-
6345937 10.1002/jso.2930230311 1:STN:280:DyaL3s3ktlWhtw%3D%3D
-
Lee YT (1983) Breast carcinoma: pattern of metastasis at autopsy. J Surg Oncol 23:175-180
-
(1983)
J Surg Oncol
, vol.23
, pp. 175-180
-
-
Lee, Y.T.1
-
5
-
-
0018887334
-
Causes of death in breast cancer: A clinicopathologic study
-
7388758 10.1002/1097-0142(19800701)46:1<162: AID-CNCR2820460127>3. 0.CO;2-B
-
Hagemeister FB Jr, Buzdar AU, Luna MA, Blumenschein GR (1980) Causes of death in breast cancer: a clinicopathologic study. Cancer 46:162-167
-
(1980)
Cancer
, vol.46
, pp. 162-167
-
-
Hagemeister, Jr.F.B.1
Buzdar, A.U.2
Luna, M.A.3
Blumenschein, G.R.4
-
6
-
-
0018888910
-
Causes of death and metastatic patterns in patients with mammary cancer. Ten-year autopsy study
-
6243853 1:STN:280:DyaL3c7islensw%3D%3D
-
Cho SY, Choi HY (1980) Causes of death and metastatic patterns in patients with mammary cancer. Ten-year autopsy study. Am J Clin Pathol 73:232-234
-
(1980)
Am J Clin Pathol
, vol.73
, pp. 232-234
-
-
Cho, S.Y.1
Choi, H.Y.2
-
7
-
-
0024337144
-
Studies of the HER-2/neu proto-oncogene in human breast and ovarian cancer
-
2470152 10.1126/science.2470152 1:STN:280:DyaL1M3kt1Wntg%3D%3D
-
Slamon DJ, Godolphin W, Jones LA, Holt JA, Wong SG, Keith DE, Levin WJ, Stuart SG, Udove J, Ullrich A (1989) Studies of the HER-2/neu proto-oncogene in human breast and ovarian cancer. Science 244:707-712
-
(1989)
Science
, vol.244
, pp. 707-712
-
-
Slamon, D.J.1
Godolphin, W.2
Jones, L.A.3
Holt, J.A.4
Wong, S.G.5
Keith, D.E.6
Levin, W.J.7
Stuart, S.G.8
Udove, J.9
Ullrich, A.10
-
8
-
-
36148992565
-
Breast cancer brain metastases
-
17717635 10.1007/s10555-007-9083-x
-
Cheng X, Hung MC (2007) Breast cancer brain metastases. Cancer Metastasis Rev 26:635-643
-
(2007)
Cancer Metastasis Rev
, vol.26
, pp. 635-643
-
-
Cheng, X.1
Hung, M.C.2
-
9
-
-
12744279331
-
Increased risk of brain metastases in patients with HER-2/neu-positive breast carcinoma
-
15578684 10.1002/cncr.20813
-
Altaha R, Crowell E, Hobbs G, Higa G, Abraham J (2005) Increased risk of brain metastases in patients with HER-2/neu-positive breast carcinoma. Cancer 103:442-443
-
(2005)
Cancer
, vol.103
, pp. 442-443
-
-
Altaha, R.1
Crowell, E.2
Hobbs, G.3
Higa, G.4
Abraham, J.5
-
10
-
-
79960429096
-
Central nervous system metastases in patients with HER2-positive metastatic breast cancer: Incidence, treatment, and survival in patients from registHER
-
21768129 10.1158/1078-0432.CCR-10-2962 1:CAS:528:DC%2BC3MXovFehtLs%3D
-
Brufsky AM, Mayer M, Rugo HS, Kaufman PA, Tan-Chiu E, Tripathy D, Tudor IC, Wang LI, Brammer MG, Shing M, Yood MU, Yardley DA (2011) Central nervous system metastases in patients with HER2-positive metastatic breast cancer: incidence, treatment, and survival in patients from registHER. Clin Cancer Res 17:4834-4843
-
(2011)
Clin Cancer Res
, vol.17
, pp. 4834-4843
-
-
Brufsky, A.M.1
Mayer, M.2
Rugo, H.S.3
Kaufman, P.A.4
Tan-Chiu, E.5
Tripathy, D.6
Tudor, I.C.7
Wang, L.I.8
Brammer, M.G.9
Shing, M.10
Yood, M.U.11
Yardley, D.A.12
-
11
-
-
33645104239
-
Incidence, pattern and timing of brain metastases among patients with advanced breast cancer treated with trastuzumab
-
16546866 10.1080/02841860500486630 1:CAS:528:DC%2BD28Xis1Cit7c%3D
-
Yau T, Swanton C, Chua S, Sue A, Walsh G, Rostom A, Johnston SR, O'Brien ME, Smith IE (2006) Incidence, pattern and timing of brain metastases among patients with advanced breast cancer treated with trastuzumab. Acta Oncol 45:196-201
-
(2006)
Acta Oncol
, vol.45
, pp. 196-201
-
-
Yau, T.1
Swanton, C.2
Chua, S.3
Sue, A.4
Walsh, G.5
Rostom, A.6
Johnston, S.R.7
O'Brien, M.E.8
Smith, I.E.9
-
12
-
-
0038010542
-
Central nervous system metastases in women who receive trastuzumab-based therapy for metastatic breast carcinoma
-
12784331 10.1002/cncr.11436
-
Bendell JC, Domchek SM, Burstein HJ, Harris L, Younger J, Kuter I, Bunnell C, Rue M, Gelman R, Winer E (2003) Central nervous system metastases in women who receive trastuzumab-based therapy for metastatic breast carcinoma. Cancer 97:2972-2977
-
(2003)
Cancer
, vol.97
, pp. 2972-2977
-
-
Bendell, J.C.1
Domchek, S.M.2
Burstein, H.J.3
Harris, L.4
Younger, J.5
Kuter, I.6
Bunnell, C.7
Rue, M.8
Gelman, R.9
Winer, E.10
-
13
-
-
4344691784
-
Incidence of cerebral metastases in patients treated with trastuzumab for metastatic breast cancer
-
15266327 1:CAS:528:DC%2BD2cXmsVCgs7k%3D
-
Clayton AJ, Danson S, Jolly S, Ryder WD, Burt PA, Stewart AL, Wilkinson PM, Welch RS, Magee B, Wilson G, Howell A, Wardley AM (2004) Incidence of cerebral metastases in patients treated with trastuzumab for metastatic breast cancer. Br J Cancer 91:639-643
-
(2004)
Br J Cancer
, vol.91
, pp. 639-643
-
-
Clayton, A.J.1
Danson, S.2
Jolly, S.3
Ryder, W.D.4
Burt, P.A.5
Stewart, A.L.6
Wilkinson, P.M.7
Welch, R.S.8
Magee, B.9
Wilson, G.10
Howell, A.11
Wardley, A.M.12
-
14
-
-
33646372698
-
Characteristics of patients with brain metastases receiving trastuzumab for HER2 overexpressing metastatic breast cancer
-
16026983 10.1016/j.breast.2005.04.017 1:STN:280:DC%2BD28zptVCqtA%3D%3D
-
Stemmler HJ, Kahlert S, Siekiera W, Untch M, Heinrich B, Heinemann V (2006) Characteristics of patients with brain metastases receiving trastuzumab for HER2 overexpressing metastatic breast cancer. Breast 15:219-225
-
(2006)
Breast
, vol.15
, pp. 219-225
-
-
Stemmler, H.J.1
Kahlert, S.2
Siekiera, W.3
Untch, M.4
Heinrich, B.5
Heinemann, V.6
-
15
-
-
62549135630
-
Trastuzumab treatment improves brain metastasis outcomes through control and durable prolongation of systemic extracranial disease in HER2-overexpressing breast cancer patients
-
19240719 10.1038/sj.bjc.6604941 1:CAS:528:DC%2BD1MXjt1Gjsb8%3D
-
Park YH, Park MJ, Ji SH, Yi SY, Lim DH, Nam DH, Lee JI, Park W, Choi DH, Huh SJ, Ahn JS, Kang WK, Park K, Im YH (2009) Trastuzumab treatment improves brain metastasis outcomes through control and durable prolongation of systemic extracranial disease in HER2-overexpressing breast cancer patients. Br J Cancer 100:894-900
-
(2009)
Br J Cancer
, vol.100
, pp. 894-900
-
-
Park, Y.H.1
Park, M.J.2
Ji, S.H.3
Yi, S.Y.4
Lim, D.H.5
Nam, D.H.6
Lee, J.I.7
Park, W.8
Choi, D.H.9
Huh, S.J.10
Ahn, J.S.11
Kang, W.K.12
Park, K.13
Im, Y.H.14
-
16
-
-
33646869874
-
Identifying breast cancer patients at risk for Central Nervous System (CNS) metastases in trials of the International Breast Cancer Study Group (IBCSG)
-
16603601 10.1093/annonc/mdl064 1:STN:280:DC%2BD283nslenuw%3D%3D
-
Pestalozzi BC, Zahrieh D, Price KN, Holmberg SB, Lindtner J, Collins J, Crivellari D, Fey MF, Murray E, Pagani O, Simoncini E, Castiglione-Gertsch M, Gelber RD, Coates AS, Goldhirsch A (2006) Identifying breast cancer patients at risk for Central Nervous System (CNS) metastases in trials of the International Breast Cancer Study Group (IBCSG). Ann Oncol 17:935-944
-
(2006)
Ann Oncol
, vol.17
, pp. 935-944
-
-
Pestalozzi, B.C.1
Zahrieh, D.2
Price, K.N.3
Holmberg, S.B.4
Lindtner, J.5
Collins, J.6
Crivellari, D.7
Fey, M.F.8
Murray, E.9
Pagani, O.10
Simoncini, E.11
Castiglione-Gertsch, M.12
Gelber, R.D.13
Coates, A.S.14
Goldhirsch, A.15
-
17
-
-
0026059293
-
Association of c-erbB-2 protein over-expression with high rate of cell proliferation, increased risk of visceral metastasis and poor long-term survival in breast cancer
-
1682277 10.1002/ijc.2910490504 1:STN:280:DyaK38%2FktVelsQ%3D%3D
-
Kallioniemi OP, Holli K, Visakorpi T, Koivula T, Helin HH, Isola JJ (1991) Association of c-erbB-2 protein over-expression with high rate of cell proliferation, increased risk of visceral metastasis and poor long-term survival in breast cancer. Int J Cancer 49:650-655
-
(1991)
Int J Cancer
, vol.49
, pp. 650-655
-
-
Kallioniemi, O.P.1
Holli, K.2
Visakorpi, T.3
Koivula, T.4
Helin, H.H.5
Isola, J.J.6
-
18
-
-
34247346051
-
Prognostic significance of human epidermal growth factor receptor positivity for the development of brain metastasis after newly diagnosed breast cancer
-
17102066 10.1200/JCO.2006.07.0250 1:CAS:528:DC%2BD2sXhtVChsrc%3D
-
Gabos Z, Sinha R, Hanson J, Chauhan N, Hugh J, Mackey JR, Abdulkarim B (2006) Prognostic significance of human epidermal growth factor receptor positivity for the development of brain metastasis after newly diagnosed breast cancer. J Clin Oncol 24:5658-5663
-
(2006)
J Clin Oncol
, vol.24
, pp. 5658-5663
-
-
Gabos, Z.1
Sinha, R.2
Hanson, J.3
Chauhan, N.4
Hugh, J.5
MacKey, J.R.6
Abdulkarim, B.7
-
19
-
-
51049123414
-
A six-gene signature predicting breast cancer lung metastasis
-
18676831 10.1158/0008-5472.CAN-08-0436 1:CAS:528:DC%2BD1cXpt1Sqtb4%3D
-
Landemaine T, Jackson A, Bellahcene A, Rucci N, Sin S, Abad BM, Sierra A, Boudinet A, Guinebretiere JM, Ricevuto E, Nogues C, Briffod M, Bieche I, Cherel P, Garcia T, Castronovo V, Teti A, Lidereau R, Driouch K (2008) A six-gene signature predicting breast cancer lung metastasis. Cancer Res 68:6092-6099
-
(2008)
Cancer Res
, vol.68
, pp. 6092-6099
-
-
Landemaine, T.1
Jackson, A.2
Bellahcene, A.3
Rucci, N.4
Sin, S.5
Abad, B.M.6
Sierra, A.7
Boudinet, A.8
Guinebretiere, J.M.9
Ricevuto, E.10
Nogues, C.11
Briffod, M.12
Bieche, I.13
Cherel, P.14
Garcia, T.15
Castronovo, V.16
Teti, A.17
Lidereau, R.18
Driouch, K.19
-
20
-
-
13444268127
-
Distinct organ-specific metastatic potential of individual breast cancer cells and primary tumors
-
15630443 1:CAS:528:DC%2BD2MXis1eluw%3D%3D
-
Minn AJ, Kang Y, Serganova I, Gupta GP, Giri DD, Doubrovin M, Ponomarev V, Gerald WL, Blasberg R, Massague J (2005) Distinct organ-specific metastatic potential of individual breast cancer cells and primary tumors. J Clin Invest 115:44-55
-
(2005)
J Clin Invest
, vol.115
, pp. 44-55
-
-
Minn, A.J.1
Kang, Y.2
Serganova, I.3
Gupta, G.P.4
Giri, D.D.5
Doubrovin, M.6
Ponomarev, V.7
Gerald, W.L.8
Blasberg, R.9
Massague, J.10
-
21
-
-
84871617801
-
13-gene signature to predict rapid development of brain metastases in patients with HER2-positive advanced breast cancer
-
Polish Brain Metastasis Consortium, Military Institute of Medicine WP, Medical University of Gdansk GP, Indiana University School of Medicine II, Wolfson Institute of Preventive Medicine LUK, National Cancer Institute BM, National Institutes of Health BM, Bialystock Oncology Center BP, Opole Oncological Center OP, Institute for Oncology and Radiology BSaM, Indiana University Simon Cancer Center II Abstract 505
-
Duchnowska R, Jassem J, Goswami CP, Gokem-Polar Y, Thorat MA, Flores N, Hua E, Woditschka S, Palmieri D, Steinberg S, Biernat W, Sosinka-Mielcarek K, Szostkiewicz B, Czartoryska-Arlukowicz B, Radecka B, Tomasevic Z, Sledge GW, Steeg PS, Badve SS, Polish Brain Metastasis Consortium, Military Institute of Medicine WP, Medical University of Gdansk GP, Indiana University School of Medicine II, Wolfson Institute of Preventive Medicine LUK, National Cancer Institute BM, National Institutes of Health BM, Bialystock Oncology Center BP, Opole Oncological Center OP, Institute for Oncology and Radiology BSaM, Indiana University Simon Cancer Center II (2012) 13-gene signature to predict rapid development of brain metastases in patients with HER2-positive advanced breast cancer. J Clin Oncol 30:Abstract 505
-
(2012)
J Clin Oncol
, vol.30
-
-
Duchnowska, R.1
Jassem, J.2
Goswami, C.P.3
Gokem-Polar, Y.4
Ma, T.5
Flores, N.6
Hua, E.7
Woditschka, S.8
Palmieri, D.9
Steinberg, S.10
Biernat, W.11
Sosinka-Mielcarek, K.12
Szostkiewicz, B.13
Czartoryska-Arlukowicz, B.14
Radecka, B.15
Tomasevic, Z.16
Sledge, G.W.17
Steeg, P.S.18
Badve, S.S.19
-
22
-
-
3543083922
-
The risk of central nervous system metastases after trastuzumab therapy in patients with breast carcinoma
-
15305414 10.1002/cncr.20418 1:CAS:528:DC%2BD2cXntlSqtbo%3D
-
Lai R, Dang CT, Malkin MG, Abrey LE (2004) The risk of central nervous system metastases after trastuzumab therapy in patients with breast carcinoma. Cancer 101:810-816
-
(2004)
Cancer
, vol.101
, pp. 810-816
-
-
Lai, R.1
Dang, C.T.2
Malkin, M.G.3
Abrey, L.E.4
-
23
-
-
0041696795
-
Increased rate of brain metastasis with trastuzumab therapy not associated with impaired survival
-
12864939 10.3816/CBC.2003.n.016 1:CAS:528:DC%2BD3sXmt1Olsrk%3D
-
Lower EE, Drosick DR, Blau R, Brennan L, Danneman W, Hawley DK (2003) Increased rate of brain metastasis with trastuzumab therapy not associated with impaired survival. Clin Breast Cancer 4:114-119
-
(2003)
Clin Breast Cancer
, vol.4
, pp. 114-119
-
-
Lower, E.E.1
Drosick, D.R.2
Blau, R.3
Brennan, L.4
Danneman, W.5
Hawley, D.K.6
-
24
-
-
27744440126
-
Isolated central nervous system metastases in patients with HER2-overexpressing advanced breast cancer treated with first-line trastuzumab-based therapy
-
16150805 10.1093/annonc/mdi371 1:STN:280:DC%2BD2MrlvFGlsA%3D%3D
-
Burstein HJ, Lieberman G, Slamon DJ, Winer EP, Klein P (2005) Isolated central nervous system metastases in patients with HER2-overexpressing advanced breast cancer treated with first-line trastuzumab-based therapy. Ann Oncol 16:1772-1777
-
(2005)
Ann Oncol
, vol.16
, pp. 1772-1777
-
-
Burstein, H.J.1
Lieberman, G.2
Slamon, D.J.3
Winer, E.P.4
Klein, P.5
-
25
-
-
26844536978
-
Trastuzumab plus adjuvant chemotherapy for operable HER2-positive breast cancer
-
16236738 10.1056/NEJMoa052122 1:CAS:528:DC%2BD2MXhtFansr3F
-
Romond EH, Perez EA, Bryant J, Suman VJ, Geyer CE Jr, Davidson NE, Tan-Chiu E, Martino S, Paik S, Kaufman PA, Swain SM, Pisansky TM, Fehrenbacher L, Kutteh LA, Vogel VG, Visscher DW, Yothers G, Jenkins RB, Brown AM, Dakhil SR, Mamounas EP, Lingle WL, Klein PM, Ingle JN, Wolmark N (2005) Trastuzumab plus adjuvant chemotherapy for operable HER2-positive breast cancer. N Engl J Med 353:1673-1684
-
(2005)
N Engl J Med
, vol.353
, pp. 1673-1684
-
-
Romond, E.H.1
Perez, E.A.2
Bryant, J.3
Suman, V.J.4
Geyer, Jr.C.E.5
Davidson, N.E.6
Tan-Chiu, E.7
Martino, S.8
Paik, S.9
Kaufman, P.A.10
Swain, S.M.11
Pisansky, T.M.12
Fehrenbacher, L.13
Kutteh, L.A.14
Vogel, V.G.15
Visscher, D.W.16
Yothers, G.17
Jenkins, R.B.18
Brown, A.M.19
Dakhil, S.R.20
Mamounas, E.P.21
Lingle, W.L.22
Klein, P.M.23
Ingle, J.N.24
Wolmark, N.25
more..
-
26
-
-
33845914783
-
2-year follow-up of trastuzumab after adjuvant chemotherapy in HER2-positive breast cancer: A randomised controlled trial
-
17208639 10.1016/S0140-6736(07)60028-2 1:CAS:528:DC%2BD2sXit12itg%3D%3D
-
Smith I, Procter M, Gelber RD, Guillaume S, Feyereislova A, Dowsett M, Goldhirsch A, Untch M, Mariani G, Baselga J, Kaufmann M, Cameron D, Bell R, Bergh J, Coleman R, Wardley A, Harbeck N, Lopez RI, Mallmann P, Gelmon K, Wilcken N, Wist E, Sanchez RP, Piccart-Gebhart MJ (2007) 2-year follow-up of trastuzumab after adjuvant chemotherapy in HER2-positive breast cancer: a randomised controlled trial. Lancet 369:29-36
-
(2007)
Lancet
, vol.369
, pp. 29-36
-
-
Smith, I.1
Procter, M.2
Gelber, R.D.3
Guillaume, S.4
Feyereislova, A.5
Dowsett, M.6
Goldhirsch, A.7
Untch, M.8
Mariani, G.9
Baselga, J.10
Kaufmann, M.11
Cameron, D.12
Bell, R.13
Bergh, J.14
Coleman, R.15
Wardley, A.16
Harbeck, N.17
Lopez, R.I.18
Mallmann, P.19
Gelmon, K.20
Wilcken, N.21
Wist, E.22
Sanchez, R.P.23
Piccart-Gebhart, M.J.24
more..
-
27
-
-
38549134656
-
Cardiotoxicity and incidence of brain metastases after adjuvant trastuzumab for early breast cancer: The dark side of the moon? A meta-analysis of the randomized trials
-
17638068 10.1007/s10549-007-9663-z 1:CAS:528:DC%2BD1cXlsV2nt74%3D
-
Bria E, Cuppone F, Fornier M, Nistico C, Carlini P, Milella M, Sperduti I, Terzoli E, Cognetti F, Giannarelli D (2008) Cardiotoxicity and incidence of brain metastases after adjuvant trastuzumab for early breast cancer: the dark side of the moon? A meta-analysis of the randomized trials. Breast Cancer Res Treat 109:231-239
-
(2008)
Breast Cancer Res Treat
, vol.109
, pp. 231-239
-
-
Bria, E.1
Cuppone, F.2
Fornier, M.3
Nistico, C.4
Carlini, P.5
Milella, M.6
Sperduti, I.7
Terzoli, E.8
Cognetti, F.9
Giannarelli, D.10
-
28
-
-
34548444589
-
Adjuvant trastuzumab in the treatment of her-2-positive early breast cancer: A meta-analysis of published randomized trials
-
17686164 10.1186/1471-2407-7-153
-
Viani GA, Afonso SL, Stefano EJ, De Fendi LI, Soares FV (2007) Adjuvant trastuzumab in the treatment of her-2-positive early breast cancer: a meta-analysis of published randomized trials. BMC Cancer 7:153
-
(2007)
BMC Cancer
, vol.7
, pp. 153
-
-
Viani, G.A.1
Afonso, S.L.2
Stefano, E.J.3
De Fendi, L.I.4
Soares, F.V.5
-
29
-
-
84887267911
-
Incidence and risk of central nervous system (CNS) metastases as a site of first recurrence in patients (pts) with HER2-positive (HER2+) breast cancer treated with adjuvant trastuzumab (T)
-
Abstract 609
-
Olson EM, Abdel-Rasoul M, Sing-Ying Wu C, Maly J, Pan XJ, Shapiro CL (2012) Incidence and risk of central nervous system (CNS) metastases as a site of first recurrence in patients (pts) with HER2-positive (HER2+) breast cancer treated with adjuvant trastuzumab (T). J Clin Oncol 30:Abstract 609
-
(2012)
J Clin Oncol
, vol.30
-
-
Olson, E.M.1
Abdel-Rasoul, M.2
Sing-Ying Wu, C.3
Maly, J.4
Pan, X.J.5
Shapiro, C.L.6
-
30
-
-
77953787668
-
Brain metastases and breast cancer subtypes
-
20389139 10.1159/000296307
-
Gonzalez-Angulo AM, Hortobagyi GN (2010) Brain metastases and breast cancer subtypes. Onkologie 33:143-144
-
(2010)
Onkologie
, vol.33
, pp. 143-144
-
-
Gonzalez-Angulo, A.M.1
Hortobagyi, G.N.2
-
31
-
-
33747163007
-
Primary breast cancer phenotypes associated with propensity for central nervous system metastases
-
16826579 10.1002/cncr.22041
-
Tham YL, Sexton K, Kramer R, Hilsenbeck S, Elledge R (2006) Primary breast cancer phenotypes associated with propensity for central nervous system metastases. Cancer 107:696-704
-
(2006)
Cancer
, vol.107
, pp. 696-704
-
-
Tham, Y.L.1
Sexton, K.2
Kramer, R.3
Hilsenbeck, S.4
Elledge, R.5
-
32
-
-
84871775256
-
RegistHER: Patient characteristics and time course of central nervous system metastases in patients with HER2-positive metastatic breast cancer
-
Abstract 89
-
Brufsky A, Rugo HS, Kaufman PA, Tan-Chiu E, Yood M, Tripathy D, Birkner M, Brammer MG, Yardley DA (2008) RegistHER: Patient characteristics and time course of central nervous system metastases in patients with HER2-positive metastatic breast cancer. J Clin Oncol 26:Abstract 89
-
(2008)
J Clin Oncol
, vol.26
-
-
Brufsky, A.1
Rugo, H.S.2
Kaufman, P.A.3
Tan-Chiu, E.4
Yood, M.5
Tripathy, D.6
Birkner, M.7
Brammer, M.G.8
Yardley, D.A.9
-
33
-
-
46249099391
-
Defining prognosis for women with breast cancer and CNS metastases by HER2 status
-
18334512 10.1093/annonc/mdn036 1:STN:280:DC%2BD1cvgvVOkuw%3D%3D
-
Dawood S, Broglio K, Esteva FJ, Ibrahim NK, Kau SW, Islam R, Aldape KD, Yu TK, Hortobagyi GN, Gonzalez-Angulo AM (2008) Defining prognosis for women with breast cancer and CNS metastases by HER2 status. Ann Oncol 19:1242-1248
-
(2008)
Ann Oncol
, vol.19
, pp. 1242-1248
-
-
Dawood, S.1
Broglio, K.2
Esteva, F.J.3
Ibrahim, N.K.4
Kau, S.W.5
Islam, R.6
Aldape, K.D.7
Yu, T.K.8
Hortobagyi, G.N.9
Gonzalez-Angulo, A.M.10
-
34
-
-
36348947965
-
Trastuzumab prolongs overall survival in patients with brain metastases from Her2 positive breast cancer
-
17557136 10.1007/s11060-007-9420-5 1:CAS:528:DC%2BD2sXhsVygt77E
-
Bartsch R, Rottenfusser A, Wenzel C, Dieckmann K, Pluschnig U, Altorjai G, Rudas M, Mader RM, Poetter R, Zielinski CC, Steger GG (2007) Trastuzumab prolongs overall survival in patients with brain metastases from Her2 positive breast cancer. J Neurooncol 85:311-317
-
(2007)
J Neurooncol
, vol.85
, pp. 311-317
-
-
Bartsch, R.1
Rottenfusser, A.2
Wenzel, C.3
Dieckmann, K.4
Pluschnig, U.5
Altorjai, G.6
Rudas, M.7
Mader, R.M.8
Poetter, R.9
Zielinski, C.C.10
Steger, G.G.11
-
35
-
-
44949181989
-
Extended survival in women with brain metastases from HER2 overexpressing breast cancer
-
18525303 10.1097/COC.0b013e31815a43c4 1:CAS:528:DC%2BD1cXntFWgu7k%3D
-
Church DN, Modgil R, Guglani S, Bahl A, Hopkins K, Braybrooke JP, Blair P, Price CG (2008) Extended survival in women with brain metastases from HER2 overexpressing breast cancer. Am J Clin Oncol 31:250-254
-
(2008)
Am J Clin Oncol
, vol.31
, pp. 250-254
-
-
Church, D.N.1
Modgil, R.2
Guglani, S.3
Bahl, A.4
Hopkins, K.5
Braybrooke, J.P.6
Blair, P.7
Price, C.G.8
-
36
-
-
33845694512
-
Delivery of chemotherapy and antibodies across the blood-brain barrier and the role of chemoprotection, in primary and metastatic brain tumors: Report of the Eleventh Annual Blood-Brain Barrier Consortium meeting
-
16858513 10.1007/s11060-006-9209-y
-
Doolittle ND, Peereboom DM, Christoforidis GA, Hall WA, Palmieri D, Brock PR, Campbell KC, Dickey DT, Muldoon LL, O'Neill BP, Peterson DR, Pollock B, Soussain C, Smith Q, Tyson RM, Neuwelt EA (2007) Delivery of chemotherapy and antibodies across the blood-brain barrier and the role of chemoprotection, in primary and metastatic brain tumors: report of the Eleventh Annual Blood-Brain Barrier Consortium meeting. J Neurooncol 81:81-91
-
(2007)
J Neurooncol
, vol.81
, pp. 81-91
-
-
Doolittle, N.D.1
Peereboom, D.M.2
Christoforidis, G.A.3
Hall, W.A.4
Palmieri, D.5
Brock, P.R.6
Campbell, K.C.7
Dickey, D.T.8
Muldoon, L.L.9
O'Neill, B.P.10
Peterson, D.R.11
Pollock, B.12
Soussain, C.13
Smith, Q.14
Tyson, R.M.15
Neuwelt, E.A.16
-
37
-
-
4444309646
-
CNS metastases in breast cancer
-
15337811 10.1200/JCO.2004.01.175
-
Lin NU, Bellon JR, Winer EP (2004) CNS metastases in breast cancer. J Clin Oncol 22:3608-3617
-
(2004)
J Clin Oncol
, vol.22
, pp. 3608-3617
-
-
Lin, N.U.1
Bellon, J.R.2
Winer, E.P.3
-
38
-
-
78650378532
-
Heterogeneous blood-tumor barrier permeability determines drug efficacy in mouse brain metastases of breast cancer
-
20829328 10.1158/1078-0432.CCR-10-1564 1:CAS:528:DC%2BC3cXhsFamtL3F
-
Lockman PR, Mittapalli RK, Taskar KS, Rudraraju V, Gril B, Bohn KA, Adkins CE, Roberts A, Thorsheim HR, Gaasch JA, Huang S, Palmieri D, Steeg PS, Smith QR (2010) Heterogeneous blood-tumor barrier permeability determines drug efficacy in mouse brain metastases of breast cancer. Clin Cancer Res 16:5664-5678
-
(2010)
Clin Cancer Res
, vol.16
, pp. 5664-5678
-
-
Lockman, P.R.1
Mittapalli, R.K.2
Taskar, K.S.3
Rudraraju, V.4
Gril, B.5
Bohn, K.A.6
Adkins, C.E.7
Roberts, A.8
Thorsheim, H.R.9
Gaasch, J.A.10
Huang, S.11
Palmieri, D.12
Steeg, P.S.13
Smith, Q.R.14
-
39
-
-
54449102442
-
Chemotherapy in breast cancer patients with brain metastases: Have new chemotherapic agents changed the clinical outcome?
-
18550383 10.1016/j.critrevonc.2008.04.004
-
Tosoni A, Franceschi E, Brandes AA (2008) Chemotherapy in breast cancer patients with brain metastases: have new chemotherapic agents changed the clinical outcome? Crit Rev Oncol Hematol 68:212-221
-
(2008)
Crit Rev Oncol Hematol
, vol.68
, pp. 212-221
-
-
Tosoni, A.1
Franceschi, E.2
Brandes, A.A.3
-
40
-
-
0036632353
-
Changes in blood-brain barrier permeability induced by radiotherapy: Implications for timing of chemotherapy? (Review)
-
12066192
-
van Vulpen M, Kal HB, Taphoorn MJ, El-Sharouni SY (2002) Changes in blood-brain barrier permeability induced by radiotherapy: implications for timing of chemotherapy? (Review). Oncol Rep 9:683-688
-
(2002)
Oncol Rep
, vol.9
, pp. 683-688
-
-
Van Vulpen, M.1
Kal, H.B.2
Taphoorn, M.J.3
El-Sharouni, S.Y.4
-
41
-
-
79952073192
-
The role of the organ microenvironment in brain metastasis
-
21167939 10.1016/j.semcancer.2010.12.009
-
Fidler IJ (2011) The role of the organ microenvironment in brain metastasis. Semin Cancer Biol 21:107-112
-
(2011)
Semin Cancer Biol
, vol.21
, pp. 107-112
-
-
Fidler, I.J.1
-
42
-
-
34250177984
-
The blood-brain barrier and cancer: Transporters, treatment, and Trojan horses
-
17363519 10.1158/1078-0432.CCR-06-2854 1:CAS:528:DC%2BD2sXivV2gtrg%3D
-
Deeken JF, Loscher W (2007) The blood-brain barrier and cancer: transporters, treatment, and Trojan horses. Clin Cancer Res 13:1663-1674
-
(2007)
Clin Cancer Res
, vol.13
, pp. 1663-1674
-
-
Deeken, J.F.1
Loscher, W.2
-
43
-
-
75649093779
-
Disruption of the blood brain barrier by brain metastases of triple-negative and basal-type breast cancer but not HER2/neu-positive breast cancer
-
19937674 10.1002/cncr.24735
-
Yonemori K, Tsuta K, Ono M, Shimizu C, Hirakawa A, Hasegawa T, Hatanaka Y, Narita Y, Shibui S, Fujiwara Y (2010) Disruption of the blood brain barrier by brain metastases of triple-negative and basal-type breast cancer but not HER2/neu-positive breast cancer. Cancer 116:302-308
-
(2010)
Cancer
, vol.116
, pp. 302-308
-
-
Yonemori, K.1
Tsuta, K.2
Ono, M.3
Shimizu, C.4
Hirakawa, A.5
Hasegawa, T.6
Hatanaka, Y.7
Narita, Y.8
Shibui, S.9
Fujiwara, Y.10
-
44
-
-
14044264295
-
Temozolomide (TMZ) combined with cisplatin (CDDP) in patients with brain metastases from solid tumors: A Hellenic Cooperative Oncology Group (HeCOG) Phase II study
-
15719277 10.1007/s11060-004-9176-0 1:CAS:528:DC%2BD2MXhtlCjsLfK
-
Christodoulou C, Bafaloukos D, Linardou H, Aravantinos G, Bamias A, Carina M, Klouvas G, Skarlos D (2005) Temozolomide (TMZ) combined with cisplatin (CDDP) in patients with brain metastases from solid tumors: a Hellenic Cooperative Oncology Group (HeCOG) Phase II study. J Neurooncol 71:61-65
-
(2005)
J Neurooncol
, vol.71
, pp. 61-65
-
-
Christodoulou, C.1
Bafaloukos, D.2
Linardou, H.3
Aravantinos, G.4
Bamias, A.5
Carina, M.6
Klouvas, G.7
Skarlos, D.8
-
45
-
-
34347355387
-
Phase II study of temozolomide and concomitant whole-brain radiotherapy in patients with brain metastases from solid tumors
-
17596744 10.1159/000102557 1:CAS:528:DC%2BD2sXntVSltrk%3D
-
Kouvaris JR, Miliadou A, Kouloulias VE, Kolokouris D, Balafouta MJ, Papacharalampous XN, Vlahos LJ (2007) Phase II study of temozolomide and concomitant whole-brain radiotherapy in patients with brain metastases from solid tumors. Onkologie 30:361-366
-
(2007)
Onkologie
, vol.30
, pp. 361-366
-
-
Kouvaris, J.R.1
Miliadou, A.2
Kouloulias, V.E.3
Kolokouris, D.4
Balafouta, M.J.5
Papacharalampous, X.N.6
Vlahos, L.J.7
-
46
-
-
55549112218
-
Phase 2 trial of temozolomide using protracted low-dose and whole-brain radiotherapy for nonsmall cell lung cancer and breast cancer patients with brain metastases
-
18798231 10.1002/cncr.23859 1:CAS:528:DC%2BD1cXhtlKru77F
-
Addeo R, De Rosa C, Faiola V, Leo L, Cennamo G, Montella L, Guarrasi R, Vincenzi B, Caraglia M, del Prete S (2008) Phase 2 trial of temozolomide using protracted low-dose and whole-brain radiotherapy for nonsmall cell lung cancer and breast cancer patients with brain metastases. Cancer 113:2524-2531
-
(2008)
Cancer
, vol.113
, pp. 2524-2531
-
-
Addeo, R.1
De Rosa, C.2
Faiola, V.3
Leo, L.4
Cennamo, G.5
Montella, L.6
Guarrasi, R.7
Vincenzi, B.8
Caraglia, M.9
Del Prete, S.10
-
47
-
-
77949638554
-
Dose-dense temozolomide regimen for the treatment of brain metastases from melanoma, breast cancer, or lung cancer not amenable to surgery or radiosurgery: A multicenter phase II study
-
19767314 10.1093/annonc/mdp343 1:STN:280:DC%2BC3c7isVGmsA%3D%3D
-
Siena S, Crino L, Danova M, Del PS, Cascinu S, Salvagni S, Schiavetto I, Vitali M, Bajetta E (2010) Dose-dense temozolomide regimen for the treatment of brain metastases from melanoma, breast cancer, or lung cancer not amenable to surgery or radiosurgery: a multicenter phase II study. Ann Oncol 21:655-661
-
(2010)
Ann Oncol
, vol.21
, pp. 655-661
-
-
Siena, S.1
Crino, L.2
Danova, M.3
Del, P.S.4
Cascinu, S.5
Salvagni, S.6
Schiavetto, I.7
Vitali, M.8
Bajetta, E.9
-
48
-
-
0019946071
-
Phase II clinical trial of cis dichlorodiammine platinum (Cis DDP) in metastatic brain tumors
-
6761344 10.1007/BF00406247 1:STN:280:DyaL3s7jsF2nsw%3D%3D
-
Kolaric K, Roth A, Jelicic I, Matkovic A (1982) Phase II clinical trial of cis dichlorodiammine platinum (Cis DDP) in metastatic brain tumors. J Cancer Res Clin Oncol 104:287-293
-
(1982)
J Cancer Res Clin Oncol
, vol.104
, pp. 287-293
-
-
Kolaric, K.1
Roth, A.2
Jelicic, I.3
Matkovic, A.4
-
49
-
-
0030744082
-
Phase II trial of cisplatinum and etoposide in brain metastases of solid tumors
-
9266451 10.1023/A:1005835430489 1:STN:280:DyaK2svhtFCksQ%3D%3D
-
Vinolas N, Graus F, Mellado B, Caralt L, Estape J (1997) Phase II trial of cisplatinum and etoposide in brain metastases of solid tumors. J Neurooncol 35:145-148
-
(1997)
J Neurooncol
, vol.35
, pp. 145-148
-
-
Vinolas, N.1
Graus, F.2
Mellado, B.3
Caralt, L.4
Estape, J.5
-
50
-
-
0033120802
-
Front-line chemotherapy with cisplatin and etoposide for patients with brain metastases from breast carcinoma, nonsmall cell lung carcinoma, or malignant melanoma: A prospective study
-
10193952 10.1002/(SICI)1097-0142(19990401)85:7<1599: AID-CNCR23>3.0.CO;2-# 1:CAS:528:DyaK1MXitlaqs7g%3D
-
Franciosi V, Cocconi G, Michiara M, Di CF, Fosser V, Tonato M, Carlini P, Boni C, Di SS (1999) Front-line chemotherapy with cisplatin and etoposide for patients with brain metastases from breast carcinoma, nonsmall cell lung carcinoma, or malignant melanoma: a prospective study. Cancer 85:1599-1605
-
(1999)
Cancer
, vol.85
, pp. 1599-1605
-
-
Franciosi, V.1
Cocconi, G.2
Michiara, M.3
Di, C.F.4
Fosser, V.5
Tonato, M.6
Carlini, P.7
Boni, C.8
Di, S.S.9
-
51
-
-
55549128225
-
A phase 2 trial of whole-brain radiotherapy combined with intravenous chemotherapy in patients with brain metastases from breast cancer
-
18780315 10.1002/cncr.23858 1:CAS:528:DC%2BD1cXhtlKru7%2FM
-
Cassier PA, Ray-Coquard I, Sunyach MP, Lancry L, Guastalla JP, Ferlay C, Gomez F, Cure H, Lortholary A, Claude L, Blay JY, Bachelot T (2008) A phase 2 trial of whole-brain radiotherapy combined with intravenous chemotherapy in patients with brain metastases from breast cancer. Cancer 113:2532-2538
-
(2008)
Cancer
, vol.113
, pp. 2532-2538
-
-
Cassier, P.A.1
Ray-Coquard, I.2
Sunyach, M.P.3
Lancry, L.4
Guastalla, J.P.5
Ferlay, C.6
Gomez, F.7
Cure, H.8
Lortholary, A.9
Claude, L.10
Blay, J.Y.11
Bachelot, T.12
-
52
-
-
35448952569
-
Capecitabine therapy of central nervous system metastases from breast cancer
-
17611719 10.1007/s11060-007-9409-0 1:CAS:528:DC%2BD2sXhtl2gs7rI
-
Ekenel M, Hormigo AM, Peak S, DeAngelis LM, Abrey LE (2007) Capecitabine therapy of central nervous system metastases from breast cancer. J Neurooncol 85:223-227
-
(2007)
J Neurooncol
, vol.85
, pp. 223-227
-
-
Ekenel, M.1
Hormigo, A.M.2
Peak, S.3
Deangelis, L.M.4
Abrey, L.E.5
-
53
-
-
67349192199
-
Concurrent capecitabine and whole-brain radiotherapy for treatment of brain metastases in breast cancer patients
-
19169856 10.1007/s11060-008-9791-2 1:CAS:528:DC%2BD1MXmsVClsbo%3D
-
Chargari C, Kirova YM, Dieras V, Castro PP, Campana F, Cottu PH, Pierga J, Fourquet A (2009) Concurrent capecitabine and whole-brain radiotherapy for treatment of brain metastases in breast cancer patients. J Neurooncol 93:379-384
-
(2009)
J Neurooncol
, vol.93
, pp. 379-384
-
-
Chargari, C.1
Kirova, Y.M.2
Dieras, V.3
Castro, P.P.4
Campana, F.5
Cottu, P.H.6
Pierga, J.7
Fourquet, A.8
-
54
-
-
77951474500
-
Biodistribution of 89Zr-trastuzumab and PET imaging of HER2-positive lesions in patients with metastatic breast cancer
-
20357763 10.1038/clpt.2010.12 1:CAS:528:DC%2BC3cXkvFCntLc%3D
-
Dijkers EC, Oude Munnink TH, Kosterink JG, Brouwers AH, Jager PL, de Jong JR, van Dongen GA, Schroder CP, Lub-de Hooge MN, de Vries EG (2010) Biodistribution of 89Zr-trastuzumab and PET imaging of HER2-positive lesions in patients with metastatic breast cancer. Clin Pharmacol Ther 87:586-592
-
(2010)
Clin Pharmacol Ther
, vol.87
, pp. 586-592
-
-
Dijkers, E.C.1
Oude Munnink, T.H.2
Kosterink, J.G.3
Brouwers, A.H.4
Jager, P.L.5
De Jong, J.R.6
Van Dongen, G.A.7
Schroder, C.P.8
Lub-De Hooge, M.N.9
De Vries, E.G.10
-
55
-
-
33845599378
-
Ratio of trastuzumab levels in serum and cerebrospinal fluid is altered in HER2-positive breast cancer patients with brain metastases and impairment of blood-brain barrier
-
17159499 10.1097/01.cad.0000236313.50833.ee 1:CAS:528:DC%2BD28Xht1yrt7bO
-
Stemmler HJ, Schmitt M, Willems A, Bernhard H, Harbeck N, Heinemann V (2007) Ratio of trastuzumab levels in serum and cerebrospinal fluid is altered in HER2-positive breast cancer patients with brain metastases and impairment of blood-brain barrier. Anticancer Drugs 18:23-28
-
(2007)
Anticancer Drugs
, vol.18
, pp. 23-28
-
-
Stemmler, H.J.1
Schmitt, M.2
Willems, A.3
Bernhard, H.4
Harbeck, N.5
Heinemann, V.6
-
56
-
-
3242686392
-
Sensitization of breast cancer cells to radiation by trastuzumab
-
14617784 1:CAS:528:DC%2BD3sXovFCqtLo%3D
-
Liang K, Lu Y, Jin W, Ang KK, Milas L, Fan Z (2003) Sensitization of breast cancer cells to radiation by trastuzumab. Mol Cancer Ther 2:1113-1120
-
(2003)
Mol Cancer Ther
, vol.2
, pp. 1113-1120
-
-
Liang, K.1
Lu, Y.2
Jin, W.3
Ang, K.K.4
Milas, L.5
Fan, Z.6
-
57
-
-
80053597907
-
Preliminary results of whole brain radiotherapy with concurrent trastuzumab for treatment of brain metastases in breast cancer patients
-
20932686 10.1016/j.ijrobp.2010.06.057
-
Chargari C, Idrissi HR, Pierga JY, Bollet MA, Dieras V, Campana F, Cottu P, Fourquet A, Kirova YM (2011) Preliminary results of whole brain radiotherapy with concurrent trastuzumab for treatment of brain metastases in breast cancer patients. Int J Radiat Oncol Biol Phys 81:631-636
-
(2011)
Int J Radiat Oncol Biol Phys
, vol.81
, pp. 631-636
-
-
Chargari, C.1
Idrissi, H.R.2
Pierga, J.Y.3
Bollet, M.A.4
Dieras, V.5
Campana, F.6
Cottu, P.7
Fourquet, A.8
Kirova, Y.M.9
-
58
-
-
0344758982
-
Efficacy of intracerebral microinfusion of trastuzumab in an athymic rat model of intracerebral metastatic breast cancer
-
14654531 1:CAS:528:DC%2BD3sXpsVejtLk%3D
-
Grossi PM, Ochiai H, Archer GE, McLendon RE, Zalutsky MR, Friedman AH, Friedman HS, Bigner DD, Sampson JH (2003) Efficacy of intracerebral microinfusion of trastuzumab in an athymic rat model of intracerebral metastatic breast cancer. Clin Cancer Res 9:5514-5520
-
(2003)
Clin Cancer Res
, vol.9
, pp. 5514-5520
-
-
Grossi, P.M.1
Ochiai, H.2
Archer, G.E.3
McLendon, R.E.4
Zalutsky, M.R.5
Friedman, A.H.6
Friedman, H.S.7
Bigner, D.D.8
Sampson, J.H.9
-
59
-
-
63949084960
-
Extended survival of a HER-2-positive metastatic breast cancer patient with brain metastases also treated with intrathecal trastuzumab
-
18987856 10.1007/s00280-008-0859-7
-
Colozza M, Minenza E, Gori S, Fenocchio D, Paolucci C, Aristei C, Floridi P (2009) Extended survival of a HER-2-positive metastatic breast cancer patient with brain metastases also treated with intrathecal trastuzumab. Cancer Chemother Pharmacol 63:1157-1159
-
(2009)
Cancer Chemother Pharmacol
, vol.63
, pp. 1157-1159
-
-
Colozza, M.1
Minenza, E.2
Gori, S.3
Fenocchio, D.4
Paolucci, C.5
Aristei, C.6
Floridi, P.7
-
60
-
-
0035188978
-
Use of intrathecal trastuzumab in a patient with carcinomatous meningitis
-
11899418 10.1016/S1526-8209(11)70419-0 1:STN:280:DC%2BD387mvVagtw%3D%3D
-
Laufman LR, Forsthoefel KF (2001) Use of intrathecal trastuzumab in a patient with carcinomatous meningitis. Clin Breast Cancer 2:235
-
(2001)
Clin Breast Cancer
, vol.2
, pp. 235
-
-
Laufman, L.R.1
Forsthoefel, K.F.2
-
61
-
-
54949107844
-
High-dose intrathecal trastuzumab for leptomeningeal metastases secondary to HER-2 overexpressing breast cancer
-
18845838 10.1093/annonc/mdn654 1:STN:280:DC%2BD1cnosFeluw%3D%3D
-
Mir O, Ropert S, Alexandre J, Lemare F, Goldwasser F (2008) High-dose intrathecal trastuzumab for leptomeningeal metastases secondary to HER-2 overexpressing breast cancer. Ann Oncol 19:1978-1980
-
(2008)
Ann Oncol
, vol.19
, pp. 1978-1980
-
-
Mir, O.1
Ropert, S.2
Alexandre, J.3
Lemare, F.4
Goldwasser, F.5
-
62
-
-
79958251618
-
Complete response in HER2+ leptomeningeal carcinomatosis from breast cancer with intrathecal trastuzumab
-
21369716 10.1007/s10549-011-1417-2 1:CAS:528:DC%2BC3MXmtlyrsrY%3D
-
Oliveira M, Braga S, Passos-Coelho JL, Fonseca R, Oliveira J (2011) Complete response in HER2+ leptomeningeal carcinomatosis from breast cancer with intrathecal trastuzumab. Breast Cancer Res Treat 127:841-844
-
(2011)
Breast Cancer Res Treat
, vol.127
, pp. 841-844
-
-
Oliveira, M.1
Braga, S.2
Passos-Coelho, J.L.3
Fonseca, R.4
Oliveira, J.5
-
63
-
-
33747828928
-
Meningeal carcinomatosis from breast cancer treated with intrathecal trastuzumab
-
16945774 10.1016/S1470-2045(06)70864-6
-
Platini C, Long J, Walter S (2006) Meningeal carcinomatosis from breast cancer treated with intrathecal trastuzumab. Lancet Oncol 7:778-780
-
(2006)
Lancet Oncol
, vol.7
, pp. 778-780
-
-
Platini, C.1
Long, J.2
Walter, S.3
-
64
-
-
53749101969
-
Intrathecal trastuzumab (Herceptin) and methotrexate for meningeal carcinomatosis in HER2-overexpressing metastatic breast cancer: A case report
-
18690096 10.1097/CAD.0b013e32830b58b0 1:CAS:528:DC%2BD1cXpsFKqu7o%3D
-
Stemmler HJ, Mengele K, Schmitt M, Harbeck N, Laessig D, Herrmann KA, Schaffer P, Heinemann V (2008) Intrathecal trastuzumab (Herceptin) and methotrexate for meningeal carcinomatosis in HER2-overexpressing metastatic breast cancer: a case report. Anticancer Drugs 19:832-836
-
(2008)
Anticancer Drugs
, vol.19
, pp. 832-836
-
-
Stemmler, H.J.1
Mengele, K.2
Schmitt, M.3
Harbeck, N.4
Laessig, D.5
Herrmann, K.A.6
Schaffer, P.7
Heinemann, V.8
-
65
-
-
33744939239
-
Application of intrathecal trastuzumab (Herceptintrade mark) for treatment of meningeal carcinomatosis in HER2-overexpressing metastatic breast cancer
-
16596213 1:CAS:528:DC%2BD28XksFKiurY%3D
-
Stemmler HJ, Schmitt M, Harbeck N, Willems A, Bernhard H, Lassig D, Schoenberg S, Heinemann V (2006) Application of intrathecal trastuzumab (Herceptin™) for treatment of meningeal carcinomatosis in HER2-overexpressing metastatic breast cancer. Oncol Rep 15:1373-1377
-
(2006)
Oncol Rep
, vol.15
, pp. 1373-1377
-
-
Stemmler, H.J.1
Schmitt, M.2
Harbeck, N.3
Willems, A.4
Bernhard, H.5
Lassig, D.6
Schoenberg, S.7
Heinemann, V.8
-
66
-
-
23944476155
-
Phase i safety, pharmacokinetics, and clinical activity study of lapatinib (GW572016), a reversible dual inhibitor of epidermal growth factor receptor tyrosine kinases, in heavily pretreated patients with metastatic carcinomas
-
15955900 10.1200/JCO.2005.16.584 1:CAS:528:DC%2BD2MXpslOrtL0%3D
-
Burris HA III, Hurwitz HI, Dees EC, Dowlati A, Blackwell KL, O'Neil B, Marcom PK, Ellis MJ, Overmoyer B, Jones SF, Harris JL, Smith DA, Koch KM, Stead A, Mangum S, Spector NL (2005) Phase I safety, pharmacokinetics, and clinical activity study of lapatinib (GW572016), a reversible dual inhibitor of epidermal growth factor receptor tyrosine kinases, in heavily pretreated patients with metastatic carcinomas. J Clin Oncol 23:5305-5313
-
(2005)
J Clin Oncol
, vol.23
, pp. 5305-5313
-
-
Burris III, H.A.1
Hurwitz, H.I.2
Dees, E.C.3
Dowlati, A.4
Blackwell, K.L.5
O'Neil, B.6
Marcom, P.K.7
Ellis, M.J.8
Overmoyer, B.9
Jones, S.F.10
Harris, J.L.11
Smith, D.A.12
Koch, K.M.13
Stead, A.14
Mangum, S.15
Spector, N.L.16
-
67
-
-
33845886440
-
Lapatinib plus capecitabine for HER2-positive advanced breast cancer
-
17192538 10.1056/NEJMoa064320 1:CAS:528:DC%2BD2sXhslSqsA%3D%3D
-
Geyer CE, Forster J, Lindquist D, Chan S, Romieu CG, Pienkowski T, Jagiello-Gruszfeld A, Crown J, Chan A, Kaufman B, Skarlos D, Campone M, Davidson N, Berger M, Oliva C, Rubin SD, Stein S, Cameron D (2006) Lapatinib plus capecitabine for HER2-positive advanced breast cancer. N Engl J Med 355:2733-2743
-
(2006)
N Engl J Med
, vol.355
, pp. 2733-2743
-
-
Geyer, C.E.1
Forster, J.2
Lindquist, D.3
Chan, S.4
Romieu, C.G.5
Pienkowski, T.6
Jagiello-Gruszfeld, A.7
Crown, J.8
Chan, A.9
Kaufman, B.10
Skarlos, D.11
Campone, M.12
Davidson, N.13
Berger, M.14
Oliva, C.15
Rubin, S.D.16
Stein, S.17
Cameron, D.18
-
68
-
-
73149115341
-
Lapatinib combined with letrozole versus letrozole and placebo as first-line therapy for postmenopausal hormone receptor-positive metastatic breast cancer
-
19786658 10.1200/JCO.2009.23.3734 1:CAS:528:DC%2BC3cXhtVWit7w%3D
-
Johnston S, Pippen J Jr, Pivot X, Lichinitser M, Sadeghi S, Dieras V, Gomez HL, Romieu G, Manikhas A, Kennedy MJ, Press MF, Maltzman J, Florance A, O'Rourke L, Oliva C, Stein S, Pegram M (2009) Lapatinib combined with letrozole versus letrozole and placebo as first-line therapy for postmenopausal hormone receptor-positive metastatic breast cancer. J Clin Oncol 27:5538-5546
-
(2009)
J Clin Oncol
, vol.27
, pp. 5538-5546
-
-
Johnston, S.1
Pippen, Jr.J.2
Pivot, X.3
Lichinitser, M.4
Sadeghi, S.5
Dieras, V.6
Gomez, H.L.7
Romieu, G.8
Manikhas, A.9
Kennedy, M.J.10
Press, M.F.11
Maltzman, J.12
Florance, A.13
O'Rourke, L.14
Oliva, C.15
Stein, S.16
Pegram, M.17
-
69
-
-
59649115878
-
An unexpected synergist role of P-glycoprotein and breast cancer resistance protein on the central nervous system penetration of the tyrosine kinase inhibitor lapatinib (N-{3-chloro-4-[(3-fluorobenzyl)oxy]phenyl}-6-[5- ({[2-(methylsulfonyl)ethy l]amino}methyl)-2-furyl]-4-quinazolinamine; GW572016)
-
19056914 10.1124/dmd.108.024646 1:CAS:528:DC%2BD1MXhs1Krtro%3D
-
Polli JW, Olson KL, Chism JP, John-Williams LS, Yeager RL, Woodard SM, Otto V, Castellino S, Demby VE (2009) An unexpected synergist role of P-glycoprotein and breast cancer resistance protein on the central nervous system penetration of the tyrosine kinase inhibitor lapatinib (N-{3-chloro-4-[(3-fluorobenzyl)oxy]phenyl}-6-[5-({[2-(methylsulfonyl)ethy l]amino}methyl)-2-furyl]-4-quinazolinamine; GW572016). Drug Metab Dispos 37:439-442
-
(2009)
Drug Metab Dispos
, vol.37
, pp. 439-442
-
-
Polli, J.W.1
Olson, K.L.2
Chism, J.P.3
John-Williams, L.S.4
Yeager, R.L.5
Woodard, S.M.6
Otto, V.7
Castellino, S.8
Demby, V.E.9
-
70
-
-
42949112556
-
Phase II trial of lapatinib for brain metastases in patients with human epidermal growth factor receptor 2-positive breast cancer
-
18421051 10.1200/JCO.2007.12.3588 1:CAS:528:DC%2BD1cXlvFaqs7o%3D
-
Lin NU, Carey LA, Liu MC, Younger J, Come SE, Ewend M, Harris GJ, Bullitt E, Van den Abbeele AD, Henson JW, Li X, Gelman R, Burstein HJ, Kasparian E, Kirsch DG, Crawford A, Hochberg F, Winer EP (2008) Phase II trial of lapatinib for brain metastases in patients with human epidermal growth factor receptor 2-positive breast cancer. J Clin Oncol 26:1993-1999
-
(2008)
J Clin Oncol
, vol.26
, pp. 1993-1999
-
-
Lin, N.U.1
Carey, L.A.2
Liu, M.C.3
Younger, J.4
Come, S.E.5
Ewend, M.6
Harris, G.J.7
Bullitt, E.8
Van Den Abbeele, A.D.9
Henson, J.W.10
Li, X.11
Gelman, R.12
Burstein, H.J.13
Kasparian, E.14
Kirsch, D.G.15
Crawford, A.16
Hochberg, F.17
Winer, E.P.18
-
71
-
-
63149110733
-
Multicenter phase II study of lapatinib in patients with brain metastases from HER2-positive breast cancer
-
19228746 10.1158/1078-0432.CCR-08-1080 1:CAS:528:DC%2BD1MXitVOktLo%3D
-
Lin NU, Dieras V, Paul D, Lossignol D, Christodoulou C, Stemmler HJ, Roche H, Liu MC, Greil R, Ciruelos E, Loibl S, Gori S, Wardley A, Yardley D, Brufsky A, Blum JL, Rubin SD, Dharan B, Steplewski K, Zembryki D, Oliva C, Roychowdhury D, Paoletti P, Winer EP (2009) Multicenter phase II study of lapatinib in patients with brain metastases from HER2-positive breast cancer. Clin Cancer Res 15:1452-1459
-
(2009)
Clin Cancer Res
, vol.15
, pp. 1452-1459
-
-
Lin, N.U.1
Dieras, V.2
Paul, D.3
Lossignol, D.4
Christodoulou, C.5
Stemmler, H.J.6
Roche, H.7
Liu, M.C.8
Greil, R.9
Ciruelos, E.10
Loibl, S.11
Gori, S.12
Wardley, A.13
Yardley, D.14
Brufsky, A.15
Blum, J.L.16
Rubin, S.D.17
Dharan, B.18
Steplewski, K.19
Zembryki, D.20
Oliva, C.21
Roychowdhury, D.22
Paoletti, P.23
Winer, E.P.24
more..
-
72
-
-
77949542447
-
Treatment of HER2-positive metastatic breast cancer with lapatinib and capecitabine in the lapatinib expanded access programme, including efficacy in brain metastases - The UK experience
-
20179708 10.1038/sj.bjc.6605586 1:CAS:528:DC%2BC3cXjt1ynu70%3D
-
Sutherland S, Ashley S, Miles D, Chan S, Wardley A, Davidson N, Bhatti R, Shehata M, Nouras H, Camburn T, Johnston SR (2010) Treatment of HER2-positive metastatic breast cancer with lapatinib and capecitabine in the lapatinib expanded access programme, including efficacy in brain metastases - the UK experience. Br J Cancer 102:995-1002
-
(2010)
Br J Cancer
, vol.102
, pp. 995-1002
-
-
Sutherland, S.1
Ashley, S.2
Miles, D.3
Chan, S.4
Wardley, A.5
Davidson, N.6
Bhatti, R.7
Shehata, M.8
Nouras, H.9
Camburn, T.10
Johnston, S.R.11
-
73
-
-
84864191059
-
Clinical outcomes of HER2-positive metastatic breast cancer patients with brain metastasis treated with lapatinib and capecitabine: An open-label expanded access study in Korea
-
22839200 10.1186/1471-2407-12-322
-
Ro J, Park S, Kim SB, Kim TY, Im YH, Rha SY, Chung JS, Moon H, Santillana S (2012) Clinical outcomes of HER2-positive metastatic breast cancer patients with brain metastasis treated with lapatinib and capecitabine: an open-label expanded access study in Korea. BMC Cancer 12:322
-
(2012)
BMC Cancer
, vol.12
, pp. 322
-
-
Ro, J.1
Park, S.2
Kim, S.B.3
Kim, T.Y.4
Im, Y.H.5
Rha, S.Y.6
Chung, J.S.7
Moon, H.8
Santillana, S.9
-
74
-
-
79952017724
-
Clinical outcome of patients with brain metastases from HER2-positive breast cancer treated with lapatinib and capecitabine
-
20724575 10.1093/annonc/mdq434 1:STN:280:DC%2BC3M3htV2itw%3D%3D
-
Metro G, Foglietta J, Russillo M, Stocchi L, Vidiri A, Giannarelli D, Crino L, Papaldo P, Mottolese M, Cognetti F, Fabi A, Gori S (2011) Clinical outcome of patients with brain metastases from HER2-positive breast cancer treated with lapatinib and capecitabine. Ann Oncol 22:625-630
-
(2011)
Ann Oncol
, vol.22
, pp. 625-630
-
-
Metro, G.1
Foglietta, J.2
Russillo, M.3
Stocchi, L.4
Vidiri, A.5
Giannarelli, D.6
Crino, L.7
Papaldo, P.8
Mottolese, M.9
Cognetti, F.10
Fabi, A.11
Gori, S.12
-
75
-
-
84855218212
-
LANDSCAPE: An FNCLCC phase II study with lapatinib (L) and capecitabine (C) in patients with brain metastases (BM) from HER2-positive (+) metastatic breast cancer (MBC) before whole-brain radiotherapy (WBR)
-
Abstract 509
-
Bachelot TD, Romieu G, Campone M, Dieras V, Cropet C, Roche HH, Jimenez M, Le Rhun E, Pierga J, Goncalves A, Leheurteur M, Domont J, Gutierrez M, Cure H, Ferrero J, Labbe C (2011) LANDSCAPE: An FNCLCC phase II study with lapatinib (L) and capecitabine (C) in patients with brain metastases (BM) from HER2-positive (+) metastatic breast cancer (MBC) before whole-brain radiotherapy (WBR). J Clin Oncol 29:Abstract 509
-
(2011)
J Clin Oncol
, vol.29
-
-
Bachelot, T.D.1
Romieu, G.2
Campone, M.3
Dieras, V.4
Cropet, C.5
Roche, H.H.6
Jimenez, M.7
Le Rhun, E.8
Pierga, J.9
Goncalves, A.10
Leheurteur, M.11
Domont, J.12
Gutierrez, M.13
Cure, H.14
Ferrero, J.15
Labbe, C.16
-
76
-
-
82955163167
-
Randomized phase II study of lapatinib plus capecitabine or lapatinib plus topotecan for patients with HER2-positive breast cancer brain metastases
-
21706359 10.1007/s11060-011-0629-y 1:CAS:528:DC%2BC3MXhsVyrtLfN
-
Lin NU, Eierman W, Greil R, Campone M, Kaufman B, Steplewski K, Lane SR, Zembryki D, Rubin SD, Winer EP (2011) Randomized phase II study of lapatinib plus capecitabine or lapatinib plus topotecan for patients with HER2-positive breast cancer brain metastases. J Neurooncol 105:613-620
-
(2011)
J Neurooncol
, vol.105
, pp. 613-620
-
-
Lin, N.U.1
Eierman, W.2
Greil, R.3
Campone, M.4
Kaufman, B.5
Steplewski, K.6
Lane, S.R.7
Zembryki, D.8
Rubin, S.D.9
Winer, E.P.10
-
77
-
-
56549113680
-
A phase III randomized comparison of lapatinib plus capecitabine versus capecitabine alone in women with advanced breast cancer that has progressed on trastuzumab: Updated efficacy and biomarker analyses
-
18188694 10.1007/s10549-007-9885-0 1:CAS:528:DC%2BD1cXhtl2mu7bI
-
Cameron D, Casey M, Press M, Lindquist D, Pienkowski T, Romieu CG, Chan S, Jagiello-Gruszfeld A, Kaufman B, Crown J, Chan A, Campone M, Viens P, Davidson N, Gorbounova V, Raats JI, Skarlos D, Newstat B, Roychowdhury D, Paoletti P, Oliva C, Rubin S, Stein S, Geyer CE (2008) A phase III randomized comparison of lapatinib plus capecitabine versus capecitabine alone in women with advanced breast cancer that has progressed on trastuzumab: updated efficacy and biomarker analyses. Breast Cancer Res Treat 112:533-543
-
(2008)
Breast Cancer Res Treat
, vol.112
, pp. 533-543
-
-
Cameron, D.1
Casey, M.2
Press, M.3
Lindquist, D.4
Pienkowski, T.5
Romieu, C.G.6
Chan, S.7
Jagiello-Gruszfeld, A.8
Kaufman, B.9
Crown, J.10
Chan, A.11
Campone, M.12
Viens, P.13
Davidson, N.14
Gorbounova, V.15
Raats, J.I.16
Skarlos, D.17
Newstat, B.18
Roychowdhury, D.19
Paoletti, P.20
Oliva, C.21
Rubin, S.22
Stein, S.23
Geyer, C.E.24
more..
-
78
-
-
84855348673
-
Impact of anti-HER2 therapy on overall survival in HER2-overexpressing breast cancer patients with brain metastases
-
22127284 10.1038/bjc.2011.531 1:CAS:528:DC%2BC38XktFCgtQ%3D%3D
-
Bartsch R, Berghoff A, Pluschnig U, Bago-Horvath Z, Dubsky P, Rottenfusser A, Devries C, Rudas M, Fitzal F, Dieckmann K, Mader RM, Gnant M, Zielinski CC, Steger GG (2012) Impact of anti-HER2 therapy on overall survival in HER2-overexpressing breast cancer patients with brain metastases. Br J Cancer 106:25-31
-
(2012)
Br J Cancer
, vol.106
, pp. 25-31
-
-
Bartsch, R.1
Berghoff, A.2
Pluschnig, U.3
Bago-Horvath, Z.4
Dubsky, P.5
Rottenfusser, A.6
Devries, C.7
Rudas, M.8
Fitzal, F.9
Dieckmann, K.10
Mader, R.M.11
Gnant, M.12
Zielinski, C.C.13
Steger, G.G.14
-
79
-
-
77956060394
-
High dose weekly erlotinib achieves therapeutic concentrations in CSF and is effective in leptomeningeal metastases from epidermal growth factor receptor mutant lung cancer
-
20146086 10.1007/s11060-010-0128-6
-
Clarke JL, Pao W, Wu N, Miller VA, Lassman AB (2010) High dose weekly erlotinib achieves therapeutic concentrations in CSF and is effective in leptomeningeal metastases from epidermal growth factor receptor mutant lung cancer. J Neurooncol 99:283-286
-
(2010)
J Neurooncol
, vol.99
, pp. 283-286
-
-
Clarke, J.L.1
Pao, W.2
Wu, N.3
Miller, V.A.4
Lassman, A.B.5
-
80
-
-
33749046899
-
Response and resistance in a non-small-cell lung cancer patient with an epidermal growth factor receptor mutation and leptomeningeal metastases treated with high-dose gefitinib
-
16983123 10.1200/JCO.2006.06.6126
-
Jackman DM, Holmes AJ, Lindeman N, Wen PY, Kesari S, Borras AM, Bailey C, de Jong F, Janne PA, Johnson BE (2006) Response and resistance in a non-small-cell lung cancer patient with an epidermal growth factor receptor mutation and leptomeningeal metastases treated with high-dose gefitinib. J Clin Oncol 24:4517-4520
-
(2006)
J Clin Oncol
, vol.24
, pp. 4517-4520
-
-
Jackman, D.M.1
Holmes, A.J.2
Lindeman, N.3
Wen, P.Y.4
Kesari, S.5
Borras, A.M.6
Bailey, C.7
De Jong, F.8
Janne, P.A.9
Johnson, B.E.10
-
81
-
-
77950497981
-
Neratinib, an irreversible ErbB receptor tyrosine kinase inhibitor, in patients with advanced ErbB2-positive breast cancer
-
20142587 10.1200/JCO.2009.25.8707 1:CAS:528:DC%2BC3cXksFSqtbs%3D
-
Burstein HJ, Sun Y, Dirix LY, Jiang Z, Paridaens R, Tan AR, Awada A, Ranade A, Jiao S, Schwartz G, Abbas R, Powell C, Turnbull K, Vermette J, Zacharchuk C, Badwe R (2010) Neratinib, an irreversible ErbB receptor tyrosine kinase inhibitor, in patients with advanced ErbB2-positive breast cancer. J Clin Oncol 28:1301-1307
-
(2010)
J Clin Oncol
, vol.28
, pp. 1301-1307
-
-
Burstein, H.J.1
Sun, Y.2
Dirix, L.Y.3
Jiang, Z.4
Paridaens, R.5
Tan, A.R.6
Awada, A.7
Ranade, A.8
Jiao, S.9
Schwartz, G.10
Abbas, R.11
Powell, C.12
Turnbull, K.13
Vermette, J.14
Zacharchuk, C.15
Badwe, R.16
-
82
-
-
73849142191
-
Neratinib in combination with trastuzumab for the treatment of advanced breast cancer: A phase I/II study
-
Swaby R, Blackwell K, Jiang Z, Sun Y, Dieras V, Zaman K, Zacharchuk C, Powell C, Abbas R, Thakuria M (2009) Neratinib in combination with trastuzumab for the treatment of advanced breast cancer: a phase I/II study. J Clin Oncol 27:1004
-
(2009)
J Clin Oncol
, vol.27
, pp. 1004
-
-
Swaby, R.1
Blackwell, K.2
Jiang, Z.3
Sun, Y.4
Dieras, V.5
Zaman, K.6
Zacharchuk, C.7
Powell, C.8
Abbas, R.9
Thakuria, M.10
-
83
-
-
77949693587
-
Safety and efficacy of neratinib (HKI-272) in combination with paclitaxel in ErbB2+ metastatic breast cancer
-
December 9-13, 2009, San Antonio, TX, Abstract 5081
-
Chow L, Gupta S, Hershman D, Jiang Z, Epstein R, Bondarenko I, Coughlin C, Freyman A, Zhao Y, Abbas R, Awada A (2009) Safety and efficacy of neratinib (HKI-272) in combination with paclitaxel in ErbB2+ metastatic breast cancer. Presented at the 32nd Annual CTRC-AACR San Antonio Breast Cancer Symposium; December 9-13, 2009, San Antonio, TX, Abstract 5081
-
(2009)
Presented at the 32nd Annual CTRC-AACR San Antonio Breast Cancer Symposium
-
-
Chow, L.1
Gupta, S.2
Hershman, D.3
Jiang, Z.4
Epstein, R.5
Bondarenko, I.6
Coughlin, C.7
Freyman, A.8
Zhao, Y.9
Abbas, R.10
Awada, A.11
-
84
-
-
38049038935
-
A phase i dose escalation study of BIBW 2992, an irreversible dual inhibitor of epidermal growth factor receptor 1 (EGFR) and 2 (HER2) tyrosine kinase in a 2-week on, 2-week off schedule in patients with advanced solid tumours
-
18026190 10.1038/sj.bjc.6604108 1:CAS:528:DC%2BD1cXisF2qtg%3D%3D
-
Eskens FA, Mom CH, Planting AS, Gietema JA, Amelsberg A, Huisman H, van Doorn L, Burger H, Stopfer P, Verweij J, de Vries EG (2008) A phase I dose escalation study of BIBW 2992, an irreversible dual inhibitor of epidermal growth factor receptor 1 (EGFR) and 2 (HER2) tyrosine kinase in a 2-week on, 2-week off schedule in patients with advanced solid tumours. Br J Cancer 98:80-85
-
(2008)
Br J Cancer
, vol.98
, pp. 80-85
-
-
Eskens, F.A.1
Mom, C.H.2
Planting, A.S.3
Gietema, J.A.4
Amelsberg, A.5
Huisman, H.6
Van Doorn, L.7
Burger, H.8
Stopfer, P.9
Verweij, J.10
De Vries, E.G.11
-
85
-
-
84867621201
-
Target binding properties and cellular activity of Afatinib (BIBW 2992), an irreversible ErbB Family Blocker
-
Solca F, Dahl G, Zoephel A, Bader G, Sanderson M, Klein C, Kraemer O, Himmelsbach F, Haaksma E, Adolf GR (2012) Target binding properties and cellular activity of Afatinib (BIBW 2992), an irreversible ErbB Family Blocker. J Pharmacol Exp Ther 343:342-350
-
(2012)
J Pharmacol Exp Ther
, vol.343
, pp. 342-350
-
-
Solca, F.1
Dahl, G.2
Zoephel, A.3
Bader, G.4
Sanderson, M.5
Klein, C.6
Kraemer, O.7
Himmelsbach, F.8
Haaksma, E.9
Adolf, G.R.10
-
86
-
-
84863715765
-
A phase II study of afatinib (BIBW 2992), an irreversible ErbB family blocker, in patients with HER2-positive metastatic breast cancer progressing after trastuzumab
-
Lin NU, Winer EP, Wheatley D, Carey LA, Houston S, Mendelson D, Munster P, Frakes L, Kelly S, Garcia AA, Cleator S, Uttenreuther-Fischer M, Jones H, Wind S, Vinisko R, Hickish T (2012) A phase II study of afatinib (BIBW 2992), an irreversible ErbB family blocker, in patients with HER2-positive metastatic breast cancer progressing after trastuzumab. Breast Cancer Res Treat 133:1057-1065
-
(2012)
Breast Cancer Res Treat
, vol.133
, pp. 1057-1065
-
-
Lin, N.U.1
Winer, E.P.2
Wheatley, D.3
Carey, L.A.4
Houston, S.5
Mendelson, D.6
Munster, P.7
Frakes, L.8
Kelly, S.9
Garcia, A.A.10
Cleator, S.11
Uttenreuther-Fischer, M.12
Jones, H.13
Wind, S.14
Vinisko, R.15
Hickish, T.16
-
87
-
-
77957585027
-
Phase i trial of the irreversible EGFR and HER2 kinase inhibitor BIBW 2992 in patients with advanced solid tumors
-
20679611 10.1200/JCO.2009.26.7278 1:CAS:528:DC%2BC3cXht1eqsbzF
-
Yap TA, Vidal L, Adam J, Stephens P, Spicer J, Shaw H, Ang J, Temple G, Bell S, Shahidi M, Uttenreuther-Fischer M, Stopfer P, Futreal A, Calvert H, de Bono JS, Plummer R (2010) Phase I trial of the irreversible EGFR and HER2 kinase inhibitor BIBW 2992 in patients with advanced solid tumors. J Clin Oncol 28:3965-3972
-
(2010)
J Clin Oncol
, vol.28
, pp. 3965-3972
-
-
Yap, T.A.1
Vidal, L.2
Adam, J.3
Stephens, P.4
Spicer, J.5
Shaw, H.6
Ang, J.7
Temple, G.8
Bell, S.9
Shahidi, M.10
Uttenreuther-Fischer, M.11
Stopfer, P.12
Futreal, A.13
Calvert, H.14
De Bono, J.S.15
Plummer, R.16
-
90
-
-
82255177135
-
A phase II study of sagopilone (ZK 219477; ZK-EPO) in patients with breast cancer and brain metastases
-
21697017 10.1016/j.clbc.2011.03.024 1:CAS:528:DC%2BC38Xht1agtbg%3D
-
Freedman RA, Bullitt E, Sun L, Gelman R, Harris G, Ligibel JA, Krop IE, Partridge AH, Eisenberg E, Winer EP, Lin NU (2011) A phase II study of sagopilone (ZK 219477; ZK-EPO) in patients with breast cancer and brain metastases. Clin Breast Cancer 11:376-383
-
(2011)
Clin Breast Cancer
, vol.11
, pp. 376-383
-
-
Freedman, R.A.1
Bullitt, E.2
Sun, L.3
Gelman, R.4
Harris, G.5
Ligibel, J.A.6
Krop, I.E.7
Partridge, A.H.8
Eisenberg, E.9
Winer, E.P.10
Lin, N.U.11
-
91
-
-
84863131334
-
Safety, pharmacokinetics, and activity of GRN1005, a novel conjugate of angiopep-2, a peptide facilitating brain penetration, and paclitaxel, in patients with advanced solid tumors
-
22203732 10.1158/1535-7163.MCT-11-0566 1:CAS:528:DC%2BC38XitFWltLk%3D
-
Kurzrock R, Gabrail N, Chandhasin C, Moulder S, Smith C, Brenner A, Sankhala K, Mita A, Elian K, Bouchard D, Sarantopoulos J (2012) Safety, pharmacokinetics, and activity of GRN1005, a novel conjugate of angiopep-2, a peptide facilitating brain penetration, and paclitaxel, in patients with advanced solid tumors. Mol Cancer Ther 11:308-316
-
(2012)
Mol Cancer Ther
, vol.11
, pp. 308-316
-
-
Kurzrock, R.1
Gabrail, N.2
Chandhasin, C.3
Moulder, S.4
Smith, C.5
Brenner, A.6
Sankhala, K.7
Mita, A.8
Elian, K.9
Bouchard, D.10
Sarantopoulos, J.11
-
92
-
-
12144291334
-
Association between HER-2/neu and vascular endothelial growth factor expression predicts clinical outcome in primary breast cancer patients
-
15014023 10.1158/1078-0432.CCR-0951-3 1:CAS:528:DC%2BD2cXhvFCltrs%3D
-
Konecny GE, Meng YG, Untch M, Wang HJ, Bauerfeind I, Epstein M, Stieber P, Vernes JM, Gutierrez J, Hong K, Beryt M, Hepp H, Slamon DJ, Pegram MD (2004) Association between HER-2/neu and vascular endothelial growth factor expression predicts clinical outcome in primary breast cancer patients. Clin Cancer Res 10:1706-1716
-
(2004)
Clin Cancer Res
, vol.10
, pp. 1706-1716
-
-
Konecny, G.E.1
Meng, Y.G.2
Untch, M.3
Wang, H.J.4
Bauerfeind, I.5
Epstein, M.6
Stieber, P.7
Vernes, J.M.8
Gutierrez, J.9
Hong, K.10
Beryt, M.11
Hepp, H.12
Slamon, D.J.13
Pegram, M.D.14
-
93
-
-
0034691674
-
Heregulin selectively upregulates vascular endothelial growth factor secretion in cancer cells and stimulates angiogenesis
-
10918604 10.1038/sj.onc.1203685 1:CAS:528:DC%2BD3cXlslyhsbs%3D
-
Yen L, You XL, Al Moustafa AE, Batist G, Hynes NE, Mader S, Meloche S, Alaoui-Jamali MA (2000) Heregulin selectively upregulates vascular endothelial growth factor secretion in cancer cells and stimulates angiogenesis. Oncogene 19:3460-3469
-
(2000)
Oncogene
, vol.19
, pp. 3460-3469
-
-
Yen, L.1
You, X.L.2
Al Moustafa, A.E.3
Batist, G.4
Hynes, N.E.5
Mader, S.6
Meloche, S.7
Alaoui-Jamali, M.A.8
-
94
-
-
21044443432
-
Phase i combined biological therapy of breast cancer using 2 humanized monoclonal antibodies directed against HER2 proto-oncogene and vascular endothelial growth factor (VEGF)
-
Abstract 3039
-
Pegram MD, Yeon C, Ku NC, Gaudreault J, Slamon DJ (2010) Phase I combined biological therapy of breast cancer using 2 humanized monoclonal antibodies directed against HER2 proto-oncogene and vascular endothelial growth factor (VEGF). Breast Cancer Res Treat 88:S124 (Abstract 3039)
-
(2010)
Breast Cancer Res Treat
, vol.88
-
-
Pegram, M.D.1
Yeon, C.2
Ku, N.C.3
Gaudreault, J.4
Slamon, D.J.5
-
95
-
-
67649819585
-
Bevacizumab and paclitaxel for breast cancer patients with central nervous system metastases: A case series
-
19433393 10.3816/CBC.2009.n.021 1:CAS:528:DC%2BD1MXmtlahtbw%3D
-
Labidi SI, Bachelot T, Ray-Coquard I, Mosbah K, Treilleux I, Fayette J, Favier B, Galy G, Blay JY, Guastalla JP (2009) Bevacizumab and paclitaxel for breast cancer patients with central nervous system metastases: a case series. Clin Breast Cancer 9:118-121
-
(2009)
Clin Breast Cancer
, vol.9
, pp. 118-121
-
-
Labidi, S.I.1
Bachelot, T.2
Ray-Coquard, I.3
Mosbah, K.4
Treilleux, I.5
Fayette, J.6
Favier, B.7
Galy, G.8
Blay, J.Y.9
Guastalla, J.P.10
-
96
-
-
84871735461
-
Bevacizumab, etoposide, and cisplatin (BEEP) in brain metastases of breast cancer progressing from radiotherapy: Results of the first stage of a multicenter phase II study
-
Abstract 1079
-
Lu Y-S, Chen W-W, Lin C-H, Tseng L-M, Yeh D-C, Wu P-F, Chen B-B, Chao T-C, Tsai Y-F, Huang S-M, Shih TT-F, Cheng A-F (2012) Bevacizumab, etoposide, and cisplatin (BEEP) in brain metastases of breast cancer progressing from radiotherapy: results of the first stage of a multicenter phase II study. J Clin Oncol 30:Abstract 1079
-
(2012)
J Clin Oncol
, vol.30
-
-
Lu, Y.-S.1
Chen, W.-W.2
Lin, C.-H.3
Tseng, L.-M.4
Yeh, D.-C.5
Wu, P.-F.6
Chen, B.-B.7
Chao, T.-C.8
Tsai, Y.-F.9
Huang, S.-M.10
Tt-F, S.11
Cheng, A.-F.12
-
97
-
-
0042200720
-
Occult central nervous system involvement in patients with metastatic breast cancer: Prevalence, predictive factors and impact on overall survival
-
12853349 10.1093/annonc/mdg300 1:STN:280:DC%2BD3szitlCrtg%3D%3D
-
Miller KD, Weathers T, Haney LG, Timmerman R, Dickler M, Shen J, Sledge GW Jr (2003) Occult central nervous system involvement in patients with metastatic breast cancer: prevalence, predictive factors and impact on overall survival. Ann Oncol 14:1072-1077
-
(2003)
Ann Oncol
, vol.14
, pp. 1072-1077
-
-
Miller, K.D.1
Weathers, T.2
Haney, L.G.3
Timmerman, R.4
Dickler, M.5
Shen, J.6
Sledge, Jr.G.W.7
-
98
-
-
77953571596
-
The effect of early detection of occult brain metastases in HER2-positive breast cancer patients on survival and cause of death
-
19932944 10.1016/j.ijrobp.2009.06.030
-
Niwinska A, Tacikowska M, Murawska M (2010) The effect of early detection of occult brain metastases in HER2-positive breast cancer patients on survival and cause of death. Int J Radiat Oncol Biol Phys 77:1134-1139
-
(2010)
Int J Radiat Oncol Biol Phys
, vol.77
, pp. 1134-1139
-
-
Niwinska, A.1
Tacikowska, M.2
Murawska, M.3
-
99
-
-
59649099684
-
Prophylactic cranial irradiation in advanced breast cancer: A case for caution
-
18954943 10.1016/j.ijrobp.2008.05.031
-
Huang F, Alrefae M, Langleben A, Roberge D (2009) Prophylactic cranial irradiation in advanced breast cancer: a case for caution. Int J Radiat Oncol Biol Phys 73:752-758
-
(2009)
Int J Radiat Oncol Biol Phys
, vol.73
, pp. 752-758
-
-
Huang, F.1
Alrefae, M.2
Langleben, A.3
Roberge, D.4
-
100
-
-
84867880323
-
LUX-breast 3: Randomized phase II study of afatinib alone or with vinorelbine versus investigator's choice of treatment in patients (pts) with HER2-positive breast cancer (BC) with progressive brain metastases (BM) after trastuzumab or lapatinib-based therapy
-
Abstract TPS647
-
Joensuu H, Kaci MO (2012) LUX-breast 3: Randomized phase II study of afatinib alone or with vinorelbine versus investigator's choice of treatment in patients (pts) with HER2-positive breast cancer (BC) with progressive brain metastases (BM) after trastuzumab or lapatinib-based therapy. J Clin Oncol 30:Abstract TPS647
-
(2012)
J Clin Oncol
, vol.30
-
-
Joensuu, H.1
Kaci, M.O.2
|