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Volumn 22, Issue 3, 2011, Pages 625-630

Clinical outcome of patients with brain metastases from HER2-positive breast cancer treated with lapatinib and capecitabine

Author keywords

Brain metastases; Capecitabine; Central nervous system; HER2; Lapatinib; Metastatic breast cancer

Indexed keywords

ANTHRACYCLINE; CAPECITABINE; EPIDERMAL GROWTH FACTOR RECEPTOR 2; LAPATINIB; TAXANE DERIVATIVE; TRASTUZUMAB;

EID: 79952017724     PISSN: 09237534     EISSN: 15698041     Source Type: Journal    
DOI: 10.1093/annonc/mdq434     Document Type: Article
Times cited : (144)

References (28)
  • 1
    • 37049183697 scopus 로고
    • Human breast cancer: correlation of relapse and survival with amplification of the HER-2/neu oncogene
    • Slamon DJ, Clark GM, Wong SG et al. Human breast cancer: correlation of relapse and survival with amplification of the HER-2/neu oncogene. Science 1987; 235: 177-182.
    • (1987) Science , vol.235 , pp. 177-182
    • Slamon, D.J.1    Clark, G.M.2    Wong, S.G.3
  • 2
    • 73949090721 scopus 로고    scopus 로고
    • Prognosis of women with metastatic breast cancer by HER2 status and trastuzumab treatment: an institutional-based review
    • Dawood S, Broglio K, Buzdar AU et al. Prognosis of women with metastatic breast cancer by HER2 status and trastuzumab treatment: an institutional-based review. J Clin Oncol 2010; 28: 92-98.
    • (2010) J Clin Oncol , vol.28 , pp. 92-98
    • Dawood, S.1    Broglio, K.2    Buzdar, A.U.3
  • 3
    • 34247346051 scopus 로고    scopus 로고
    • Prognostic significance of human epidermal growth factor receptor positivity for the development of brain metastasis after newly diagnosed breast cancer
    • Gabos Z, Sinha R, Hanson J et al. Prognostic significance of human epidermal growth factor receptor positivity for the development of brain metastasis after newly diagnosed breast cancer. J Clin Oncol 2006; 24: 5658-5663.
    • (2006) J Clin Oncol , vol.24 , pp. 5658-5663
    • Gabos, Z.1    Sinha, R.2    Hanson, J.3
  • 4
    • 33646869874 scopus 로고    scopus 로고
    • Identifying breast cancer patients at risk for Central Nervous System (CNS) metastases in trials of the International Breast Cancer Study Group (IBCSG)
    • Pestalozzi BC, Zahrieh D, Price KN et al. Identifying breast cancer patients at risk for Central Nervous System (CNS) metastases in trials of the International Breast Cancer Study Group (IBCSG). Ann Oncol 2006; 17: 935-944.
    • (2006) Ann Oncol , vol.17 , pp. 935-944
    • Pestalozzi, B.C.1    Zahrieh, D.2    Price, K.N.3
  • 5
    • 46149111250 scopus 로고    scopus 로고
    • Trastuzumab in the adjuvant treatment of early-stage breast cancer: a systematic review and meta-analysis of randomized controlled trials
    • Dahabreh IJ, Linardou H, Siannis F et al. Trastuzumab in the adjuvant treatment of early-stage breast cancer: a systematic review and meta-analysis of randomized controlled trials. Oncologist 2008; 13: 620-630.
    • (2008) Oncologist , vol.13 , pp. 620-630
    • Dahabreh, I.J.1    Linardou, H.2    Siannis, F.3
  • 6
    • 40649124149 scopus 로고    scopus 로고
    • Trastuzumab treatment and the risk of central nervous system (CNS) metastases
    • abstract 1018
    • Pinder MC, Chang H, Broglio KR et al. Trastuzumab treatment and the risk of central nervous system (CNS) metastases. Proc Am Soc Clin Oncol 2007; 25: abstract 1018.
    • (2007) Proc Am Soc Clin Oncol , vol.25
    • Pinder, M.C.1    Chang, H.2    Broglio, K.R.3
  • 7
    • 62549135630 scopus 로고    scopus 로고
    • Trastuzumab treatment improves brain metastasis outcomes through control and durable prolongation of systemic extracranial disease in HER2-overexpressing breast cancer patients
    • Park YH, Park MJ, Ji SH et al. Trastuzumab treatment improves brain metastasis outcomes through control and durable prolongation of systemic extracranial disease in HER2-overexpressing breast cancer patients. Br J Cancer 2009; 24(100): 894-900.
    • (2009) Br J Cancer , vol.24 , Issue.100 , pp. 894-900
    • Park, Y.H.1    Park, M.J.2    Ji, S.H.3
  • 9
    • 33845599378 scopus 로고    scopus 로고
    • Ratio of trastuzumab levels in serum and cerebrospinal fluid is altered in HER2-positive breast cancer patients with brain metastases and impairment of blood-brain barrier
    • Stemmler HJ, Schmitt M, Willems A et al. Ratio of trastuzumab levels in serum and cerebrospinal fluid is altered in HER2-positive breast cancer patients with brain metastases and impairment of blood-brain barrier. Anticancer Drugs 2007; 18: 23-28.
    • (2007) Anticancer Drugs , vol.18 , pp. 23-28
    • Stemmler, H.J.1    Schmitt, M.2    Willems, A.3
  • 10
    • 0038010542 scopus 로고    scopus 로고
    • Central nervous system metastases in women who receive trastuzumab-based therapy for metastatic breast carcinoma
    • Bendell JC, Domchek SM, Burstein HJ et al. Central nervous system metastases in women who receive trastuzumab-based therapy for metastatic breast carcinoma. Cancer 2003; 97: 2972-2977.
    • (2003) Cancer , vol.97 , pp. 2972-2977
    • Bendell, J.C.1    Domchek, S.M.2    Burstein, H.J.3
  • 11
    • 4344691784 scopus 로고    scopus 로고
    • Incidence of cerebral metastases in patients treated with trastuzumab for metastatic breast cancer
    • Clayton AJ, Danson S, Jolly S et al. Incidence of cerebral metastases in patients treated with trastuzumab for metastatic breast cancer. Br J Cancer 2004; 91: 639-643.
    • (2004) Br J Cancer , vol.91 , pp. 639-643
    • Clayton, A.J.1    Danson, S.2    Jolly, S.3
  • 12
    • 33646372698 scopus 로고    scopus 로고
    • Characteristics of patients with brain metastases receiving trastuzumab for HER2 overexpressing metastatic breast cancer
    • Stemmler HJ, Kahlert S, Siekiera W et al. Characteristics of patients with brain metastases receiving trastuzumab for HER2 overexpressing metastatic breast cancer. Breast 2006; 15: 219-225.
    • (2006) Breast , vol.15 , pp. 219-225
    • Stemmler, H.J.1    Kahlert, S.2    Siekiera, W.3
  • 13
    • 34548241776 scopus 로고    scopus 로고
    • Central nervous system metastases in HER-2 positive metastatic breast cancer patients treated with trastuzumab: incidence, survival, and risk factors
    • Gori S, Rimondini S, De Angelis V et al. Central nervous system metastases in HER-2 positive metastatic breast cancer patients treated with trastuzumab: incidence, survival, and risk factors. Oncologist 2007; 12: 766-773.
    • (2007) Oncologist , vol.12 , pp. 766-773
    • Gori, S.1    Rimondini, S.2    De Angelis, V.3
  • 14
    • 38049075754 scopus 로고    scopus 로고
    • Clinical utility of continuing trastuzumab beyond brain progression in HER-2 positive metastatic breast cancer
    • Metro G, Sperduti I, Russillo M et al. Clinical utility of continuing trastuzumab beyond brain progression in HER-2 positive metastatic breast cancer. Oncologist 2007; 12: 1467-1469.
    • (2007) Oncologist , vol.12 , pp. 1467-1469
    • Metro, G.1    Sperduti, I.2    Russillo, M.3
  • 15
    • 49449112267 scopus 로고    scopus 로고
    • Effect of lapatinib on the outgrowth of metastatic breast cancer cells to the brain
    • Gril B, Palmieri D, Bronder JL et al. Effect of lapatinib on the outgrowth of metastatic breast cancer cells to the brain. J Natl Cancer Inst 2008; 100: 1092-1103.
    • (2008) J Natl Cancer Inst , vol.100 , pp. 1092-1103
    • Gril, B.1    Palmieri, D.2    Bronder, J.L.3
  • 16
    • 56549113680 scopus 로고    scopus 로고
    • A phase III randomized comparison of lapatinib plus capecitabine versus capecitabine alone in women with advanced breast cancer that has progressed on trastuzumab: updated efficacy and biomarker analyses
    • Cameron D, Casey M, Press M et al. A phase III randomized comparison of lapatinib plus capecitabine versus capecitabine alone in women with advanced breast cancer that has progressed on trastuzumab: updated efficacy and biomarker analyses. Breast Cancer Res Treat 2008; 112: 533-543.
    • (2008) Breast Cancer Res Treat , vol.112 , pp. 533-543
    • Cameron, D.1    Casey, M.2    Press, M.3
  • 17
    • 42949112556 scopus 로고    scopus 로고
    • Phase II trial of lapatinib for brain metastases in patients with human epidermal growth factor receptor 2-positive breast cancer
    • Lin NU, Carey LA, Liu MC et al. Phase II trial of lapatinib for brain metastases in patients with human epidermal growth factor receptor 2-positive breast cancer. J Clin Oncol 2008; 26: 1993-1999.
    • (2008) J Clin Oncol , vol.26 , pp. 1993-1999
    • Lin, N.U.1    Carey, L.A.2    Liu, M.C.3
  • 18
    • 63149110733 scopus 로고    scopus 로고
    • Multicenter phase II study of lapatinib in patients with brain metastases from HER2-positive breast cancer
    • Lin NU, Diéras V, Paul D et al. Multicenter phase II study of lapatinib in patients with brain metastases from HER2-positive breast cancer. Clin Cancer Res 2009; 15: 1452-1459.
    • (2009) Clin Cancer Res , vol.15 , pp. 1452-1459
    • Lin, N.U.1    Diéras, V.2    Paul, D.3
  • 20
    • 33745317987 scopus 로고    scopus 로고
    • Dramatic regression of multiple brain metastases from breast cancer with Capecitabine: another arrow at the bow?
    • Fabi A, Vidiri A, Ferretti G et al. Dramatic regression of multiple brain metastases from breast cancer with Capecitabine: another arrow at the bow? Cancer Invest 2006; 24: 466-468.
    • (2006) Cancer Invest , vol.24 , pp. 466-468
    • Fabi, A.1    Vidiri, A.2    Ferretti, G.3
  • 21
    • 35448952569 scopus 로고    scopus 로고
    • Capecitabine therapy of central nervous system metastases from breast cancer
    • Ekenel M, Hormigo AM, Peak S et al. Capecitabine therapy of central nervous system metastases from breast cancer. J Neurooncol 2007; 85: 223-227.
    • (2007) J Neurooncol , vol.85 , pp. 223-227
    • Ekenel, M.1    Hormigo, A.M.2    Peak, S.3
  • 22
    • 59149099189 scopus 로고    scopus 로고
    • Evaluation of lapatinib (Lap) plus capecitabine (Cap) in patients with brain metastases (BM) from HER2+ breast cancer (BC) enrolled in the Lapatinib Expanded Access Program (LEAP) and French Authorisation Temporaire d'Utilisation (ATU)
    • abstract 1094
    • Boccardo F, Kaufman B, Baselga J et al. Evaluation of lapatinib (Lap) plus capecitabine (Cap) in patients with brain metastases (BM) from HER2+ breast cancer (BC) enrolled in the Lapatinib Expanded Access Program (LEAP) and French Authorisation Temporaire d'Utilisation (ATU). Proc Am Soc Clin Oncol 2008; 26: abstract 1094.
    • (2008) Proc Am Soc Clin Oncol , vol.26
    • Boccardo, F.1    Kaufman, B.2    Baselga, J.3
  • 23
    • 77949542447 scopus 로고    scopus 로고
    • Treatment of HER2-positive metastatic breast cancer with lapatinib and capecitabine in the lapatinib expanded access programme, including efficacy in brain metastases-the UK experience
    • Sutherland S, Ashley S, Miles D et al. Treatment of HER2-positive metastatic breast cancer with lapatinib and capecitabine in the lapatinib expanded access programme, including efficacy in brain metastases-the UK experience. Br J Cancer 2010; 102: 995-1002.
    • (2010) Br J Cancer , vol.102 , pp. 995-1002
    • Sutherland, S.1    Ashley, S.2    Miles, D.3
  • 24
    • 53149153173 scopus 로고    scopus 로고
    • Do HER-2 positive metastatic breast cancer patients benefit from the use of trastuzumab beyond disease progression? A mono-institutional experience and systematic review of observational studies
    • Fabi A, Metro G, Ferretti G et al. Do HER-2 positive metastatic breast cancer patients benefit from the use of trastuzumab beyond disease progression? A mono-institutional experience and systematic review of observational studies. Breast 2008; 17: 499-505.
    • (2008) Breast , vol.17 , pp. 499-505
    • Fabi, A.1    Metro, G.2    Ferretti, G.3
  • 25
    • 65349110371 scopus 로고    scopus 로고
    • Trastuzumab beyond progression in human epidermal growth factor receptor 2-positive advanced breast cancer: a German breast group 26/breast international group 03-05 study
    • von Minckwitz G, du Bois A, Schmidt M et al. Trastuzumab beyond progression in human epidermal growth factor receptor 2-positive advanced breast cancer: a German breast group 26/breast international group 03-05 study. J Clin Oncol 2009; 27: 1999-2006.
    • (2009) J Clin Oncol , vol.27 , pp. 1999-2006
    • von Minckwitz, G.1    du Bois, A.2    Schmidt, M.3
  • 26
    • 77949884661 scopus 로고    scopus 로고
    • Randomized study of lapatinib alone or in combination with trastuzumab in women with ErbB2-positive, trastuzumabrefractory metastatic breast cancer
    • Blackwell KL, Burstein HJ, Storniolo AM et al. Randomized study of lapatinib alone or in combination with trastuzumab in women with ErbB2-positive, trastuzumabrefractory metastatic breast cancer. J Clin Oncol 2010; 28: 1124-1130.
    • (2010) J Clin Oncol , vol.28 , pp. 1124-1130
    • Blackwell, K.L.1    Burstein, H.J.2    Storniolo, A.M.3
  • 27
    • 36348947965 scopus 로고    scopus 로고
    • Trastuzumab prolongs overall survival in patients with brain metastases from Her2 positive breast cancer
    • Bartsch R, Rottenfusser A, Wenzel C et al. Trastuzumab prolongs overall survival in patients with brain metastases from Her2 positive breast cancer. J Neurooncol 2007; 85: 311-117.
    • (2007) J Neurooncol , vol.85 , pp. 311-117
    • Bartsch, R.1    Rottenfusser, A.2    Wenzel, C.3
  • 28
    • 58949099515 scopus 로고    scopus 로고
    • Trastuzumab treatment beyond brain progression in HER2-positive metastatic breast cancer
    • Park IH, Ro J, Lee KS et al. Trastuzumab treatment beyond brain progression in HER2-positive metastatic breast cancer. Ann Oncol 2009; 20: 56-62.
    • (2009) Ann Oncol , vol.20 , pp. 56-62
    • Park, I.H.1    Ro, J.2    Lee, K.S.3


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