Increased risk of brain metastases in patients with HER-2/neu-positive breast carcinoma

Cancer

Volumn 103, Issue 3, 2005, Pages 442-443

  Altaha, Ramin ^a,b   Crowell, Edward ^a   Hobbs, Gerry ^a   Higa, Gerry ^a   Abraham, Jame ^a  

^a WEST VIRGINIA UNIVERSITY   (United States)

^b WEST VIRGINIA UNIVERSITY HOSPITALS   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

TRASTUZUMAB;

AGE; BLOOD BRAIN BARRIER; BRAIN METASTASIS; BREAST CARCINOMA; CANCER RISK; CORRELATION ANALYSIS; DISEASE ASSOCIATION; DISEASE COURSE; DRUG EFFICACY; DRUG PENETRATION; FLUORESCENCE IN SITU HYBRIDIZATION; GENE OVEREXPRESSION; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; MAJOR CLINICAL STUDY; MEDICAL RECORD; METASTASIS; METASTASIS POTENTIAL; NONBIOLOGICAL MODEL; ONCOGENE NEU; PRIORITY JOURNAL; PROGNOSIS; RETROSPECTIVE STUDY; REVIEW; STATISTICAL SIGNIFICANCE; UNITED STATES; UNIVERSITY HOSPITAL;

BRAIN NEOPLASMS; BREAST NEOPLASMS; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; IMMUNOHISTOCHEMISTRY; IN SITU HYBRIDIZATION, FLUORESCENCE; PROPORTIONAL HAZARDS MODELS; RECEPTOR, ERBB-2; RETROSPECTIVE STUDIES; RISK ASSESSMENT; RISK FACTORS; SURVIVAL ANALYSIS; TUMOR MARKERS, BIOLOGICAL; UP-REGULATION;

EID: 12744279331     PISSN: 0008543X     EISSN: None     Source Type: Journal    
DOI: 10.1002/cncr.20813     Document Type: Review

References (6)

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2. Bendell JC, Domchek SM, Burstein HJ, et al. Central nervous system metastases in women who receive trastuzumab-based therapy for metastatic breast carcinoma. Cancer. 2003;97:2972-2977.
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6. Lower EE, Drosick DR, Blau R, Brennan L, Danneman W, Hawley DK. Increased rate of brain metastasis with trastuzumab therapy not associated with impaired survival. Clin Breast Cancer. 2003;4:114-119.