Dioxin suppresses benzo[a]pyrene-induced mutations and DNA adduct formation through cytochrome P450 1A1 induction and (±)-anti-benzo[a]pyrene-7,8-diol-9,10-epoxide inactivation in human hepatoma cells

Mutation Research - Genetic Toxicology and Environmental Mutagenesis

Volumn 750, Issue 1-2, 2013, Pages 77-85

  Shiizaki, Kazuhiro ^a   Kawanishi, Masanobu ^a   Yagi, Takashi ^a  

^a Osaka Prefecture University   (Japan)

Author keywords

Benzo a pyrene; BPDE; Cytochrome P450 1A1; DNA adduct; TCDD

Indexed keywords

2,3,7,8 TETRACHLORODIBENZO PARA DIOXIN; BENZO[A]PYRENE; CYTOCHROME P450 1A1; CYTOCHROME P450 2A1; CYTOCHROME P450 3A4; DNA; GLUCURONOSYLTRANSFERASE 1A1; MESSENGER RNA;

ANIMAL CELL; ARTICLE; BIOTRANSFORMATION; CATALYSIS; GENE EXPRESSION; GENE MUTATION; HEPATOMA CELL; HUMAN; HUMAN CELL; NONHUMAN; PRIORITY JOURNAL;

7,8-DIHYDRO-7,8-DIHYDROXYBENZO(A)PYRENE 9,10-OXIDE; ANIMALS; CARCINOMA, HEPATOCELLULAR; CELL LINE, TUMOR; CYTOCHROME P-450 CYP1A1; DIOXINS; DNA ADDUCTS; HUMANS; MICE; MUTATION; TETRACHLORODIBENZODIOXIN;

MURINAE;

EID: 84871718541     PISSN: 13835718     EISSN: 18793592     Source Type: Journal    
DOI: 10.1016/j.mrgentox.2012.09.008     Document Type: Article

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