Sequential metabolism of 2,3,7-trichlorodibenzo-p-dioxin (2,3,7-triCDD) by cytochrome P450 and UDP-glucuronosyltransferase in human liver microsomes

Drug Metabolism and Disposition

Volumn 32, Issue 8, 2004, Pages 870-875

  Kasai, Noriyuki ^a   Sakaki, Toshiyuki ^a,b   Shinkyo, Raku ^a   Ikushiro, Shin Ichi ^c   Iyanagi, Takashi ^f   Kamao, Maya ^d   Okano, Toshio ^d   Ohta, Miho ^e   Inouye, Kuniyo ^a  

^a KYOTO UNIVERSITY   (Japan)

^b TOYAMA PREFECTURAL UNIVERSITY   (Japan)

^c UNIVERSITY OF HYOGO   (Japan)

^d KOBE PHARMACEUTICAL UNIVERSITY   (Japan)

^e Koshien Junior College   (Japan)

^f NONE

Author keywords

[No Author keywords available]

Indexed keywords

2,3,7 TRICHLORODIBENZO PARA DIOXIN; 8 HYDROXY 2,3,7 TRICHLORODIBENZO PARA DIOXIN; CYTOCHROME P450; DIOXIN; GLUCURONOSYLTRANSFERASE; GLUCURONOSYLTRANSFERASE 1A1; GLUCURONOSYLTRANSFERASE 1A9; GLUCURONOSYLTRANSFERASE 2B7; UNCLASSIFIED DRUG;

ARTICLE; BACULOVIRUS; CHEMICAL REACTION KINETICS; DRUG METABOLISM; GLUCURONIDATION; HUMAN; HUMAN CELL; HYDROXYLATION; INSECT CELL; LIVER MICROSOME; PRIORITY JOURNAL; YEAST;

ANIMALS; CYTOCHROME P-450 ENZYME SYSTEM; DOSE-RESPONSE RELATIONSHIP, DRUG; GLUCURONOSYLTRANSFERASE; HUMANS; MICROSOMES, LIVER; RATS; TETRACHLORODIBENZODIOXIN;

INSECTA; UNIDENTIFIED BACULOVIRUS;

EID: 3242710218     PISSN: 00909556     EISSN: None     Source Type: Journal    
DOI: 10.1124/dmd.32.8.870     Document Type: Article

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