Identifying infants at high risk of peanut allergy: The Learning Early about Peanut Allergy (LEAP) screening study

Journal of Allergy and Clinical Immunology

Volumn 131, Issue 1, 2013, Pages

  Du Toit, George ^a   Roberts, Graham ^b   Sayre, Peter H ^c   Plaut, Marshall ^d   Bahnson, Henry T ^e   Mitchell, Herman ^e   Radulovic, Suzana ^a   Chan, Susan ^a   Fox, Adam ^a   Turcanu, Victor ^a   Lack, Gideon ^a  

^a KING'S COLLEGE LONDON   (United Kingdom)

^b UNIVERSITY OF SOUTHAMPTON   (United Kingdom)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES   (United States)

^e Rho Federal Systems   (United States)

Author keywords

allergy prevention; allergy risk factors; eczema; egg allergy; LEAP study; patient recruitment; peanut allergy; Peanut sensitization

Indexed keywords

CALCINEURIN INHIBITOR; CORTICOSTEROID; IMMUNOGLOBULIN E;

AFRICAN AMERICAN; ARTICLE; CLINICAL ASSESSMENT; COHORT ANALYSIS; CONTROLLED STUDY; CORTICOSTEROID THERAPY; DIAGNOSTIC TEST ACCURACY STUDY; DISEASE ASSOCIATION; DISEASE SEVERITY; ECZEMA; EGG ALLERGY; FEMALE; HIGH RISK INFANT; HUMAN; IMMUNE RESPONSE; IMMUNOGLOBULIN BLOOD LEVEL; INFANT; LEARNING EARLY ABOUT PEANUT ALLERGY; MAJOR CLINICAL STUDY; MALE; OBSERVATIONAL STUDY; PEANUT; PEANUT ALLERGY; PRICK TEST; PRIORITY JOURNAL; PROSPECTIVE STUDY; QUESTIONNAIRE; RACE DIFFERENCE; SCREENING TEST; SENSITIVITY AND SPECIFICITY; SKIN PRICK TEST; SKIN SENSITIZATION; SKIN TEST; URTICARIA;

EID: 84871714117     PISSN: 00916749     EISSN: 10976825     Source Type: Journal    
DOI: 10.1016/j.jaci.2012.09.015     Document Type: Article

References (33)

1. G. Du Toit, Y. Katz, P. Sasieni, D. Mesher, S.J. Maleki, and R. Fisher Early consumption of peanuts in infancy is associated with a low prevalence of peanut allergy J Allergy Clin Immunol 122 2008 984 991
2. J. Grundy, S. Matthews, B. Bateman, T. Dean, and S.H. Arshad Rising prevalence of allergy to peanut in children: data from 2 sequential cohorts J Allergy Clin Immunol 110 2002 784 789
3. A.H. Liu, R. Jaramillo, S.H. Sicherer, R.A. Wood, S.A. Bock, and A.W. Burks National prevalence and risk factors for food allergy and relationship to asthma: results from the National Health and Nutrition Examination Survey 2005-2006 J Allergy Clin Immunol 126 2010 798 806 e13
4. C. Venter, S. Hasan Arshad, J. Grundy, B. Pereira, C. Bernie Clayton, and K. Voight Time trends in the prevalence of peanut allergy: three cohorts of children from the same geographical location in the UK Allergy 65 2010 103 108
5. S.H. Sicherer, A. Munoz-Furlong, J.H. Godbold, and H.A. Sampson US prevalence of self-reported peanut, tree nut, and sesame allergy: 11-year follow-up J Allergy Clin Immunol 125 2010 1322 1326
6. N.J. Osborne, J.J. Koplin, P.E. Martin, L.C. Gurrin, A.J. Lowe, and M.C. Matheson Prevalence of challenge-proven IgE-mediated food allergy using population-based sampling and predetermined challenge criteria in infants J Allergy Clin Immunol 127 2011 668 676 e1-2
7. R. Kumar, H.J. Tsai, X. Hong, X. Liu, G. Wang, and C. Pearson Race, ancestry, and development of food-allergen sensitization in early childhood Pediatrics 128 2011 e821 e829
8. S.A. Bock, A. Munoz-Furlong, and H.A. Sampson Fatalities due to anaphylactic reactions to foods J Allergy Clin Immunol 107 2001 191 193
9. D.M. Fleischer, M.K. Conover-Walker, L. Christie, A.W. Burks, and R.A. Wood The natural progression of peanut allergy: resolution and the possibility of recurrence J Allergy Clin Immunol 112 2003 183 189
10. J.O. Hourihane, S.A. Kilburn, P. Dean, and J.O. Warner Clinical characteristics of peanut allergy Clin Exp Allergy 27 1997 634 639
11. D.A. Moneret-Vautrin, M. Morisset, J. Flabbee, E. Beaudouin, and G. Kanny Epidemiology of life-threatening and lethal anaphylaxis: a review Allergy 60 2005 443 451
12. H.A. Sampson, L. Mendelson, and J.P. Rosen Fatal and near-fatal anaphylactic reactions to food in children and adolescents N Engl J Med 327 1992 380 384
13. S.H. Sicherer, R.A. Wood, D. Stablein, A.W. Burks, A.H. Liu, and S.M. Jones Immunologic features of infants with milk or egg allergy enrolled in an observational study (Consortium of Food Allergy Research) of food allergy J Allergy Clin Immunol 125 2010 1077 1083 e8
14. G. Lack, D. Fox, K. Northstone, and J. Golding Factors associated with the development of peanut allergy in childhood N Engl J Med 348 2003 977 985
15. S.H. Sicherer, R.A. Wood, D. Stablein, R. Lindblad, A.W. Burks, and A.H. Liu Maternal consumption of peanut during pregnancy is associated with peanut sensitization in atopic infants J Allergy Clin Immunol 126 2010 1191 1197
16. R.S. Zeiger, and S. Heller The development and prediction of atopy in high-risk children: follow-up at age seven years in a prospective randomized study of combined maternal and infant food allergen avoidance J Allergy Clin Immunol 95 1995 1179 1190
17. F.R. Greer, S.H. Sicherer, and A.W. Burks Effects of early nutritional interventions on the development of atopic disease in infants and children: the role of maternal dietary restriction, breastfeeding, timing of introduction of complementary foods, and hydrolyzed formulas Pediatrics 121 2008 183 191
18. A. Host, S. Halken, A. Muraro, S. Dreborg, B. Niggemann, and R. Aalberse Dietary prevention of allergic diseases in infants and small children Pediatr Allergy Immunol 19 2008 1 4
19. J.A. Boyce, A. Assa'ad, A.W. Burks, S.M. Jones, H.A. Sampson, and C.A. Woos Jr. Guidelines for the diagnosis and management of food allergy in the United States: report of the NIAID-sponsored expert panel J Allergy Clin Immunol 126 suppl 2010 S1 S58
20. LEAP Study Team. ITN032AD Learning Early About Peanut Allergy (The LEAP Study). Clinicaltrialsgov 2010. Available at: http://clinicaltrials.gov/ct2/ show/NCT00329784?term=LEAP&rank=6. Accessed October 10, 2012
21. D.J. Hill, C.S. Hosking, F.M. de Benedictis, A.P. Oranje, T.L. Diepgen, and V. Bauchau Confirmation of the association between high levels of immunoglobulin E food sensitization and eczema in infancy: an international study Clin Exp Allergy 38 2008 161 168
22. H.A. Sampson Clinical practice Peanut allergy N Engl J Med 346 2002 1294 1299
23. F. Rance, M. Abbal, and V. Lauwers-Cances Improved screening for peanut allergy by the combined use of skin prick tests and specific IgE assays J Allergy Clin Immunol 109 2002 1027 1033
24. G. Roberts, and G. Lack Diagnosing peanut allergy with skin prick and specific IgE testing J Allergy Clin Immunol 115 2005 1291 1296
25. H.A. Sampson, and D.G. Ho Relationship between food-specific IgE concentrations and the risk of positive food challenges in children and adolescents J Allergy Clin Immunol 100 1997 444 451
26. H.A. Sampson Utility of food-specific IgE concentrations in predicting symptomatic food allergy J Allergy Clin Immunol 107 2001 891 896
27. R. Sporik, D.J. Hill, and C.S. Hosking Specificity of allergen skin testing in predicting positive open food challenges to milk, egg and peanut in children Clin Exp Allergy 30 2000 1540 1546
28. D.J. Hill, R.G. Heine, and C.S. Hosking The diagnostic value of skin prick testing in children with food allergy Pediatr Allergy Immunol 15 2004 435 441
29. B. Kunz, A.P. Oranje, L. Labreze, J.F. Stalder, J. Ring, and A. Taieb Clinical validation and guidelines for the SCORAD index: consensus report of the European Task Force on Atopic Dermatitis Dermatology 195 1997 10 19
30. T.D. Dang, M. Tang, S. Choo, P.V. Licciardi, J.J. Koplin, and P.E. Martin Increasing the accuracy of peanut allergy diagnosis by using Ara h 2 J Allergy Clin Immunol 129 2012 1056 1063
31. A.M. Branum, and S.L. Lukacs Food allergy among children in the United States Pediatrics 124 2009 1549 1555
32. G. Du Toit, A. Santos, G. Roberts, A.T. Fox, P. Smith, and G. Lack The diagnosis of IgE-mediated food allergy in childhood Pediatr Allergy Immunol 20 2009 309 319
33. A. DunnGalvin, D. Daly, C. Cullinane, E. Stenke, D. Keeton, and M. Erlewyn-Lajeunesse Highly accurate prediction of food challenge outcome using routinely available clinical data J Allergy Clin Immunol 127 2011 633 639 e1-3