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Volumn 7, Issue 12, 2012, Pages

Gene Expression Profiling Combined with Bioinformatics Analysis Identify Biomarkers for Parkinson Disease

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGICAL MARKER; EARLY GROWTH RESPONSE FACTOR 3; HEPATIC LEUKEMIA FACTOR; STAT4 PROTEIN; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR E2F1; TRANSCRIPTION FACTOR NKX3.1; TRANSCRIPTION FACTOR RFX1; TRANSCRIPTION FACTOR TAL1; UNCLASSIFIED DRUG;

EID: 84871675217     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0052319     Document Type: Article
Times cited : (24)

References (43)
  • 1
    • 77954840500 scopus 로고    scopus 로고
    • Parkinson disease: Progress towards a molecular biomarker for Parkinson disease
    • Foulds P, Mann DM, Mitchell JD, Allsop D, (2010) Parkinson disease: Progress towards a molecular biomarker for Parkinson disease. Nat Rev Neurol 6: 359-361.
    • (2010) Nat Rev Neurol , vol.6 , pp. 359-361
    • Foulds, P.1    Mann, D.M.2    Mitchell, J.D.3    Allsop, D.4
  • 2
    • 41149163183 scopus 로고    scopus 로고
    • Parkinson's disease: clinical features and diagnosis
    • Jankovic J, (2008) Parkinson's disease: clinical features and diagnosis. J Neurol Neurosurg Psychiatry 79: 368-376.
    • (2008) J Neurol Neurosurg Psychiatry , vol.79 , pp. 368-376
    • Jankovic, J.1
  • 3
    • 34248146514 scopus 로고    scopus 로고
    • Interaction between genes and environment in neurodegenerative diseases
    • Elbaz A, Dufouil C, Alperovitch A, (2007) Interaction between genes and environment in neurodegenerative diseases. C R Biol 330: 318-328.
    • (2007) C R Biol , vol.330 , pp. 318-328
    • Elbaz, A.1    Dufouil, C.2    Alperovitch, A.3
  • 4
    • 77956362155 scopus 로고    scopus 로고
    • Protein homeostasis and aging in neurodegeneration
    • Douglas PM, Dillin A, (2010) Protein homeostasis and aging in neurodegeneration. J Cell Biol 190: 719-729.
    • (2010) J Cell Biol , vol.190 , pp. 719-729
    • Douglas, P.M.1    Dillin, A.2
  • 6
    • 0032888789 scopus 로고    scopus 로고
    • Alpha-synuclein in Lewy body disease and Alzheimer's disease
    • Hashimoto M, Masliah E, (1999) Alpha-synuclein in Lewy body disease and Alzheimer's disease. Brain Pathol 9: 707-720.
    • (1999) Brain Pathol , vol.9 , pp. 707-720
    • Hashimoto, M.1    Masliah, E.2
  • 7
    • 70350759686 scopus 로고    scopus 로고
    • Pathogenesis of familial Parkinson's disease: new insights based on monogenic forms of Parkinson's disease
    • Hatano T, Kubo S, Sato S, Hattori N, (2009) Pathogenesis of familial Parkinson's disease: new insights based on monogenic forms of Parkinson's disease. J Neurochem 111: 1075-1093.
    • (2009) J Neurochem , vol.111 , pp. 1075-1093
    • Hatano, T.1    Kubo, S.2    Sato, S.3    Hattori, N.4
  • 8
    • 79958233724 scopus 로고    scopus 로고
    • Salivary alpha-synuclein and DJ-1: potential biomarkers for Parkinson's disease
    • Devic I, Hwang H, Edgar JS, Izutsu K, Presland R, et al. (2011) Salivary alpha-synuclein and DJ-1: potential biomarkers for Parkinson's disease. Brain 134: e178.
    • (2011) Brain , vol.134
    • Devic, I.1    Hwang, H.2    Edgar, J.S.3    Izutsu, K.4    Presland, R.5
  • 9
    • 33646833404 scopus 로고    scopus 로고
    • Increased level of DJ-1 in the cerebrospinal fluids of sporadic Parkinson's disease
    • Waragai M, Wei J, Fujita M, Nakai M, Ho GJ, et al. (2006) Increased level of DJ-1 in the cerebrospinal fluids of sporadic Parkinson's disease. Biochem Biophys Res Commun 345: 967-972.
    • (2006) Biochem Biophys Res Commun , vol.345 , pp. 967-972
    • Waragai, M.1    Wei, J.2    Fujita, M.3    Nakai, M.4    Ho, G.J.5
  • 10
    • 38049011407 scopus 로고    scopus 로고
    • Secretion of DJ-1 into the serum of patients with Parkinson's disease
    • Maita C, Tsuji S, Yabe I, Hamada S, Ogata A, et al. (2008) Secretion of DJ-1 into the serum of patients with Parkinson's disease. Neurosci Lett 431: 86-89.
    • (2008) Neurosci Lett , vol.431 , pp. 86-89
    • Maita, C.1    Tsuji, S.2    Yabe, I.3    Hamada, S.4    Ogata, A.5
  • 11
    • 33748325848 scopus 로고    scopus 로고
    • Decreased alpha-synuclein in cerebrospinal fluid of aged individuals and subjects with Parkinson's disease
    • Tokuda T, Salem SA, Allsop D, Mizuno T, Nakagawa M, et al. (2006) Decreased alpha-synuclein in cerebrospinal fluid of aged individuals and subjects with Parkinson's disease. Biochem Biophys Res Commun 349: 162-166.
    • (2006) Biochem Biophys Res Commun , vol.349 , pp. 162-166
    • Tokuda, T.1    Salem, S.A.2    Allsop, D.3    Mizuno, T.4    Nakagawa, M.5
  • 12
    • 58149469520 scopus 로고    scopus 로고
    • Cerebrospinal fluid alpha-synuclein in neurodegenerative disorders-a marker of synapse loss?
    • Ohrfelt A, Grognet P, Andreasen N, Wallin A, Vanmechelen E, et al. (2009) Cerebrospinal fluid alpha-synuclein in neurodegenerative disorders-a marker of synapse loss? Neurosci Lett 450: 332-335.
    • (2009) Neurosci Lett , vol.450 , pp. 332-335
    • Ohrfelt, A.1    Grognet, P.2    Andreasen, N.3    Wallin, A.4    Vanmechelen, E.5
  • 13
    • 77950223687 scopus 로고    scopus 로고
    • DJ-1 and alpha-synuclein in human cerebrospinal fluid as biomarkers of Parkinson's disease
    • Hong Z, Shi M, Chung KA, Quinn JF, Peskind ER, et al. (2010) DJ-1 and alpha-synuclein in human cerebrospinal fluid as biomarkers of Parkinson's disease. Brain 133: 713-726.
    • (2010) Brain , vol.133 , pp. 713-726
    • Hong, Z.1    Shi, M.2    Chung, K.A.3    Quinn, J.F.4    Peskind, E.R.5
  • 14
    • 14744296610 scopus 로고    scopus 로고
    • Inflammatory process in Parkinson's disease: role for cytokines
    • Nagatsu T, Sawada M, (2005) Inflammatory process in Parkinson's disease: role for cytokines. Curr Pharm Des 11: 999-1016.
    • (2005) Curr Pharm Des , vol.11 , pp. 999-1016
    • Nagatsu, T.1    Sawada, M.2
  • 15
    • 15244357268 scopus 로고    scopus 로고
    • Urinary 8-hydroxydeoxyguanosine levels as a biomarker for progression of Parkinson disease
    • Sato S, Mizuno Y, Hattori N, (2005) Urinary 8-hydroxydeoxyguanosine levels as a biomarker for progression of Parkinson disease. Neurology 64: 1081-1083.
    • (2005) Neurology , vol.64 , pp. 1081-1083
    • Sato, S.1    Mizuno, Y.2    Hattori, N.3
  • 16
    • 77952564443 scopus 로고    scopus 로고
    • Increased serum insulin-like growth factor 1 in early idiopathic Parkinson's disease
    • Godau J, Herfurth M, Kattner B, Gasser T, Berg D, (2010) Increased serum insulin-like growth factor 1 in early idiopathic Parkinson's disease. J Neurol Neurosurg Psychiatry 81: 536-538.
    • (2010) J Neurol Neurosurg Psychiatry , vol.81 , pp. 536-538
    • Godau, J.1    Herfurth, M.2    Kattner, B.3    Gasser, T.4    Berg, D.5
  • 17
    • 0037805576 scopus 로고    scopus 로고
    • The KEGG database
    • discussion 101-103, 119-128, 244-152
    • Kanehisa M (2002) The KEGG database. Novartis Foundation symposium 247: 91-101; discussion 101-103, 119-128, 244-152.
    • (2002) Novartis Foundation symposium , vol.247 , pp. 91-101
    • Kanehisa, M.1
  • 18
    • 0033982936 scopus 로고    scopus 로고
    • KEGG: kyoto encyclopedia of genes and genomes
    • Kanehisa M, Goto S, (2000) KEGG: kyoto encyclopedia of genes and genomes. Nucleic Acids Res 28: 27-30.
    • (2000) Nucleic Acids Res , vol.28 , pp. 27-30
    • Kanehisa, M.1    Goto, S.2
  • 19
    • 0141993704 scopus 로고    scopus 로고
    • A gene-coexpression network for global discovery of conserved genetic modules
    • Stuart JM, Segal E, Koller D, Kim SK, (2003) A gene-coexpression network for global discovery of conserved genetic modules. Science 302: 249-255.
    • (2003) Science , vol.302 , pp. 249-255
    • Stuart, J.M.1    Segal, E.2    Koller, D.3    Kim, S.K.4
  • 20
    • 3042514191 scopus 로고    scopus 로고
    • Coexpression analysis of human genes across many microarray data sets
    • Lee HK, Hsu AK, Sajdak J, Qin J, Pavlidis P, (2004) Coexpression analysis of human genes across many microarray data sets. Genome Res 14: 1085-1094.
    • (2004) Genome Res , vol.14 , pp. 1085-1094
    • Lee, H.K.1    Hsu, A.K.2    Sajdak, J.3    Qin, J.4    Pavlidis, P.5
  • 21
    • 19344374050 scopus 로고    scopus 로고
    • Similarities and differences in genome-wide expression data of six organisms
    • Bergmann S, Ihmels J, Barkai N, (2004) Similarities and differences in genome-wide expression data of six organisms. PLoS Biol 2: E9.
    • (2004) PLoS Biol , vol.2
    • Bergmann, S.1    Ihmels, J.2    Barkai, N.3
  • 22
    • 77957813589 scopus 로고    scopus 로고
    • DCGL: an R package for identifying differentially coexpressed genes and links from gene expression microarray data
    • Liu BH, Yu H, Tu K, Li C, Li YX, et al. (2010) DCGL: an R package for identifying differentially coexpressed genes and links from gene expression microarray data. Bioinformatics 26: 2637-2638.
    • (2010) Bioinformatics , vol.26 , pp. 2637-2638
    • Liu, B.H.1    Yu, H.2    Tu, K.3    Li, C.4    Li, Y.X.5
  • 23
    • 79960892858 scopus 로고    scopus 로고
    • Link-based quantitative methods to identify differentially coexpressed genes and gene pairs
    • Yu H, Liu BH, Ye ZQ, Li C, Li YX, et al. (2011) Link-based quantitative methods to identify differentially coexpressed genes and gene pairs. BMC Bioinformatics 12: 315.
    • (2011) BMC Bioinformatics , vol.12 , pp. 315
    • Yu, H.1    Liu, B.H.2    Ye, Z.Q.3    Li, C.4    Li, Y.X.5
  • 26
    • 61449172037 scopus 로고    scopus 로고
    • Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources
    • Huang da W, Sherman BT, Lempicki RA, (2009) Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources. Nat Protoc 4: 44-57.
    • (2009) Nat Protoc , vol.4 , pp. 44-57
    • da Huang, W.1    Sherman, B.T.2    Lempicki, R.A.3
  • 27
    • 77951944593 scopus 로고    scopus 로고
    • Regulatory impact factors: unraveling the transcriptional regulation of complex traits from expression data
    • Reverter A, Hudson NJ, Nagaraj SH, Perez-Enciso M, Dalrymple BP, (2010) Regulatory impact factors: unraveling the transcriptional regulation of complex traits from expression data. Bioinformatics 26: 896-904.
    • (2010) Bioinformatics , vol.26 , pp. 896-904
    • Reverter, A.1    Hudson, N.J.2    Nagaraj, S.H.3    Perez-Enciso, M.4    Dalrymple, B.P.5
  • 28
    • 0242490780 scopus 로고    scopus 로고
    • Cytoscape: a software environment for integrated models of biomolecular interaction networks
    • Shannon P, Markiel A, Ozier O, Baliga NS, Wang JT, et al. (2003) Cytoscape: a software environment for integrated models of biomolecular interaction networks. Genome Res 13: 2498-2504.
    • (2003) Genome Res , vol.13 , pp. 2498-2504
    • Shannon, P.1    Markiel, A.2    Ozier, O.3    Baliga, N.S.4    Wang, J.T.5
  • 29
    • 36949004781 scopus 로고    scopus 로고
    • Mechanisms of Disease: biomarkers and molecular targets from microarray gene expression studies in prostate cancer
    • Cooper CS, Campbell C, Jhavar S, (2007) Mechanisms of Disease: biomarkers and molecular targets from microarray gene expression studies in prostate cancer. Nat Clin Pract Urol 4: 677-687.
    • (2007) Nat Clin Pract Urol , vol.4 , pp. 677-687
    • Cooper, C.S.1    Campbell, C.2    Jhavar, S.3
  • 31
    • 84858167696 scopus 로고    scopus 로고
    • Analyzing microarray data of Alzheimer's using cluster analysis to identify the biomarker genes
    • Guttula SV, Allam A, Gumpeny RS, (2012) Analyzing microarray data of Alzheimer's using cluster analysis to identify the biomarker genes. Int J Alzheimers Dis 2012: 649456.
    • (2012) Int J Alzheimers Dis , vol.2012 , pp. 649456
    • Guttula, S.V.1    Allam, A.2    Gumpeny, R.S.3
  • 32
    • 0033135718 scopus 로고    scopus 로고
    • Expression of E2A-HLF chimeric protein induced T-cell apoptosis, B-cell maturation arrest, and development of acute lymphoblastic leukemia
    • Honda H, Inaba T, Suzuki T, Oda H, Ebihara Y, et al. (1999) Expression of E2A-HLF chimeric protein induced T-cell apoptosis, B-cell maturation arrest, and development of acute lymphoblastic leukemia. Blood 93: 2780-2790.
    • (1999) Blood , vol.93 , pp. 2780-2790
    • Honda, H.1    Inaba, T.2    Suzuki, T.3    Oda, H.4    Ebihara, Y.5
  • 33
    • 0026744416 scopus 로고
    • Fusion of the leucine zipper gene HLF to the E2A gene in human acute B-lineage leukemia
    • Inaba T, Roberts WM, Shapiro LH, Jolly KW, Raimondi SC, et al. (1992) Fusion of the leucine zipper gene HLF to the E2A gene in human acute B-lineage leukemia. Science 257: 531-534.
    • (1992) Science , vol.257 , pp. 531-534
    • Inaba, T.1    Roberts, W.M.2    Shapiro, L.H.3    Jolly, K.W.4    Raimondi, S.C.5
  • 34
    • 0033608459 scopus 로고    scopus 로고
    • Expression patterns of the hepatic leukemia factor gene in the nervous system of developing and adult mice
    • Hitzler JK, Soares HD, Drolet DW, Inaba T, O'Connel S, et al. (1999) Expression patterns of the hepatic leukemia factor gene in the nervous system of developing and adult mice. Brain Res 820: 1-11.
    • (1999) Brain Res , vol.820 , pp. 1-11
    • Hitzler, J.K.1    Soares, H.D.2    Drolet, D.W.3    Inaba, T.4    O'Connel, S.5
  • 35
    • 0037073753 scopus 로고    scopus 로고
    • Activation of the Rb/E2F1 pathway by the nonproliferative p38 MAPK during Fas (APO1/CD95)-mediated neuronal apoptosis
    • Hou ST, Xie X, Baggley A, Park DS, Chen G, et al. (2002) Activation of the Rb/E2F1 pathway by the nonproliferative p38 MAPK during Fas (APO1/CD95)-mediated neuronal apoptosis. J Biol Chem 277: 48764-48770.
    • (2002) J Biol Chem , vol.277 , pp. 48764-48770
    • Hou, S.T.1    Xie, X.2    Baggley, A.3    Park, D.S.4    Chen, G.5
  • 36
    • 33847229429 scopus 로고    scopus 로고
    • Neuropilin-1 is a direct target of the transcription factor E2F1 during cerebral ischemia-induced neuronal death in vivo
    • Jiang SX, Sheldrick M, Desbois A, Slinn J, Hou ST, (2007) Neuropilin-1 is a direct target of the transcription factor E2F1 during cerebral ischemia-induced neuronal death in vivo. Mol Cell Biol 27: 1696-1705.
    • (2007) Mol Cell Biol , vol.27 , pp. 1696-1705
    • Jiang, S.X.1    Sheldrick, M.2    Desbois, A.3    Slinn, J.4    Hou, S.T.5
  • 37
    • 0042020021 scopus 로고    scopus 로고
    • Involvement of the transcription factor E2F1/Rb in kainic acid-induced death of murine cerebellar granule cells
    • Smith RA, Walker T, Xie X, Hou ST, (2003) Involvement of the transcription factor E2F1/Rb in kainic acid-induced death of murine cerebellar granule cells. Brain Res Mol Brain Res 116: 70-79.
    • (2003) Brain Res Mol Brain Res , vol.116 , pp. 70-79
    • Smith, R.A.1    Walker, T.2    Xie, X.3    Hou, S.T.4
  • 39
    • 77955152366 scopus 로고    scopus 로고
    • Pathogenic LRRK2 negatively regulates microRNA-mediated translational repression
    • Gehrke S, Imai Y, Sokol N, Lu B, (2010) Pathogenic LRRK2 negatively regulates microRNA-mediated translational repression. Nature 466: 637-641.
    • (2010) Nature , vol.466 , pp. 637-641
    • Gehrke, S.1    Imai, Y.2    Sokol, N.3    Lu, B.4
  • 40
    • 0028228543 scopus 로고
    • Stat4, a novel gamma interferon activation site-binding protein expressed in early myeloid differentiation
    • Yamamoto K, Quelle FW, Thierfelder WE, Kreider BL, Gilbert DJ, et al. (1994) Stat4, a novel gamma interferon activation site-binding protein expressed in early myeloid differentiation. Mol Cell Biol 14: 4342-4349.
    • (1994) Mol Cell Biol , vol.14 , pp. 4342-4349
    • Yamamoto, K.1    Quelle, F.W.2    Thierfelder, W.E.3    Kreider, B.L.4    Gilbert, D.J.5
  • 42
    • 33750363298 scopus 로고    scopus 로고
    • The roles of intracellular protein-degradation pathways in neurodegeneration
    • Rubinsztein DC, (2006) The roles of intracellular protein-degradation pathways in neurodegeneration. Nature 443: 780-786.
    • (2006) Nature , vol.443 , pp. 780-786
    • Rubinsztein, D.C.1
  • 43
    • 44949138796 scopus 로고    scopus 로고
    • A review of Parkinson's disease
    • Davie CA, (2008) A review of Parkinson's disease. Br Med Bull 86: 109-127.
    • (2008) Br Med Bull , vol.86 , pp. 109-127
    • Davie, C.A.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.