Effects of quercetin on mRNA expression of steroidogenesis genes in primary cultures of Leydig cells treated with atrazine

Toxicology in Vitro

Volumn 27, Issue 2, 2013, Pages 700-707

  Abarikwu, Sunny O ^a   Pant, Aditya B ^b   Farombi, Ebenezer O ^c  

^a REDEEMER S UNIVERSITY   (Nigeria)

^b CSIR INDIAN INSTITUTE OF TOXICOLOGY RESEARCH   (India)

^c UNIVERSITY OF IBADAN   (Nigeria)

Author keywords

Atrazine; Cyclic AMP; MRNA expression; Quercetin; Steroidogenesis genes

Indexed keywords

3(OR 17)BETA HYDROXYSTEROID DEHYDROGENASE; ANDROGEN RECEPTOR; ATRAZINE; CELL PROTEIN; CHOLESTEROL MONOOXYGENASE (SIDE CHAIN CLEAVING); CYCLIC AMP; ESTROGEN RECEPTOR ALPHA; INHIBIN A; INSULIN LIKE FACTOR 3; LUTEINIZING HORMONE RECEPTOR; MESSENGER RNA; PROTEIN CYP17A1; QUERCETIN; STEROIDOGENIC ACUTE REGULATORY PROTEIN; UNCLASSIFIED DRUG;

3BETA HYDROXYSTEROID DEHYDROGENASE GENE; ANDROGEN RECEPTOR GENE; ANIMAL CELL; ARTICLE; CELL ASSAY; CELL ISOLATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYP17A1 GENE; CYTOCHROME P450 11A1 GENE; DRUG EFFECT; DRUG MECHANISM; ESTROGEN RECEPTOR GENE; GENE; GENE EXPRESSION REGULATION; IN VITRO STUDY; INHIBIN A GENE; INSULIN LIKE FACTOR 3 GENE; LEYDIG CELL; LUTEINIZING HORMONE RECEPTOR GENE; MALE; NONHUMAN; RAT; REAL TIME POLYMERASE CHAIN REACTION; REPRODUCTIVE TOXICITY; STEROIDOGENIC ACUTE REGULATORY PROTEIN GENE; UPREGULATION;

17-HYDROXYSTEROID DEHYDROGENASES; ANIMALS; ANTIOXIDANTS; ATRAZINE; CELLS, CULTURED; CHOLESTEROL SIDE-CHAIN CLEAVAGE ENZYME; GENE EXPRESSION REGULATION; HERBICIDES; INHIBINS; INSULIN; LEYDIG CELLS; MALE; PHOSPHOPROTEINS; PROTEINS; QUERCETIN; RATS; RATS, WISTAR; RECEPTORS, STEROID; RNA, MESSENGER; STEROID 17-ALPHA-HYDROXYLASE;

EID: 84871646353     PISSN: 08872333     EISSN: 18793177     Source Type: Journal    
DOI: 10.1016/j.tiv.2012.11.005     Document Type: Article

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