메뉴 건너뛰기




Volumn 96, Issue 1, 2013, Pages 75-88

Identification of lactoferrin peptides generated by digestion with human gastrointestinal enzymes

Author keywords

Human gastrointestinal enzyme; Lactoferricin; Lactoferrin; Model digestion

Indexed keywords

LACTOFERRIN; PEPTIDE FRAGMENT;

EID: 84871623844     PISSN: 00220302     EISSN: 15253198     Source Type: Journal    
DOI: 10.3168/jds.2012-5946     Document Type: Article
Times cited : (95)

References (50)
  • 2
    • 33750129519 scopus 로고    scopus 로고
    • In vitro studies of the digestion of caprine whey proteins by human gastric and duodenal juice and the effects on selected microorganisms
    • Almaas H., Holm H., Langsrud T., Flengsrud R., Vegarud G.E. In vitro studies of the digestion of caprine whey proteins by human gastric and duodenal juice and the effects on selected microorganisms. Br. J. Nutr. 2006, 96:562-569.
    • (2006) Br. J. Nutr. , vol.96 , pp. 562-569
    • Almaas, H.1    Holm, H.2    Langsrud, T.3    Flengsrud, R.4    Vegarud, G.E.5
  • 3
    • 24944504306 scopus 로고    scopus 로고
    • Biological effects of milk proteins and their peptides with emphasis on those related to the gastrointestinal ecosystem
    • Baldi A., Ioannis P., Chiara P., Eleonora F., Roubini C., Vittorio D. Biological effects of milk proteins and their peptides with emphasis on those related to the gastrointestinal ecosystem. J. Dairy Res. 2005, 72(Spec. No.):66-72.
    • (2005) J. Dairy Res. , vol.72 , Issue.SPEC. NO. , pp. 66-72
    • Baldi, A.1    Ioannis, P.2    Chiara, P.3    Eleonora, F.4    Roubini, C.5    Vittorio, D.6
  • 4
    • 0026475489 scopus 로고
    • Antibacterial spectrum of lactoferricin-B, a potent bactericidal peptide derived from the N-terminal region of bovine lactoferrin
    • Bellamy W., Takase M., Wakabayashi H., Kawase K., Tomita M. Antibacterial spectrum of lactoferricin-B, a potent bactericidal peptide derived from the N-terminal region of bovine lactoferrin. J. Appl. Bacteriol. 1992, 73:472-479.
    • (1992) J. Appl. Bacteriol. , vol.73 , pp. 472-479
    • Bellamy, W.1    Takase, M.2    Wakabayashi, H.3    Kawase, K.4    Tomita, M.5
  • 5
    • 0020508495 scopus 로고
    • The effect of trypsin and chymotrypsin on the in vitro antimicrobial and iron-binding properties of lactoferrin in human milk and bovine colostrum. Unusual resistance of human apolactoferrin to proteolytic digestion
    • Brines R.D., Brock J.H. The effect of trypsin and chymotrypsin on the in vitro antimicrobial and iron-binding properties of lactoferrin in human milk and bovine colostrum. Unusual resistance of human apolactoferrin to proteolytic digestion. Biochim. Biophys. Acta 1983, 759:229-235.
    • (1983) Biochim. Biophys. Acta , vol.759 , pp. 229-235
    • Brines, R.D.1    Brock, J.H.2
  • 8
    • 85022241054 scopus 로고
    • Spectrophotometric assay using ortho-phthaldialdehyde for determination of proteolysis in milk and isolated milk proteins
    • Church F.C., Swaisgood H.E., Porter D.H., Catignani G.L. Spectrophotometric assay using ortho-phthaldialdehyde for determination of proteolysis in milk and isolated milk proteins. J. Dairy Sci. 1983, 66:1219-1227.
    • (1983) J. Dairy Sci. , vol.66 , pp. 1219-1227
    • Church, F.C.1    Swaisgood, H.E.2    Porter, D.H.3    Catignani, G.L.4
  • 9
    • 0031115106 scopus 로고    scopus 로고
    • Antibacterial peptides of bovine lactoferrin: Purification and characterization
    • Dionysius D.A., Milne J.M. Antibacterial peptides of bovine lactoferrin: Purification and characterization. J. Dairy Sci. 1997, 80:667-674.
    • (1997) J. Dairy Sci. , vol.80 , pp. 667-674
    • Dionysius, D.A.1    Milne, J.M.2
  • 11
    • 0036882390 scopus 로고    scopus 로고
    • Structure and mechanism of the pepsin-like family of aspartic peptidases
    • Dunn B.M. Structure and mechanism of the pepsin-like family of aspartic peptidases. Chem. Rev. 2002, 102:4431-4458.
    • (2002) Chem. Rev. , vol.102 , pp. 4431-4458
    • Dunn, B.M.1
  • 12
    • 85066894965 scopus 로고    scopus 로고
    • Scientific opinion on bovine lactoferrin
    • EFSA Panel on Dietetic Products Nutrition and Allergies
    • Scientific opinion on bovine lactoferrin. EFSA J 2012, 10:1-26. EFSA Panel on Dietetic Products Nutrition and Allergies.
    • (2012) EFSA J , vol.10 , pp. 1-26
  • 13
    • 0036153455 scopus 로고    scopus 로고
    • A physiological approach for preparing and conducting intestinal bioavailability studies using experimental systems
    • Ekmekcioglu C. A physiological approach for preparing and conducting intestinal bioavailability studies using experimental systems. Food Chem. 2002, 76:225-230.
    • (2002) Food Chem. , vol.76 , pp. 225-230
    • Ekmekcioglu, C.1
  • 14
    • 77954818390 scopus 로고    scopus 로고
    • Novel antibacterial lactoferrin peptides generated by rennet digestion and autofocusing technique
    • Elbarbary H.A., Abdou A.M., Park E.Y., Nakamura Y., Mohamed H.A., Sato K. Novel antibacterial lactoferrin peptides generated by rennet digestion and autofocusing technique. Int. Dairy J. 2010, 20:646-651.
    • (2010) Int. Dairy J. , vol.20 , pp. 646-651
    • Elbarbary, H.A.1    Abdou, A.M.2    Park, E.Y.3    Nakamura, Y.4    Mohamed, H.A.5    Sato, K.6
  • 18
    • 67649236592 scopus 로고    scopus 로고
    • Lactoferricin treatment decreases the rate of cell proliferation of a human colon cancer cell line
    • Freiburghaus C., Janicke B., Lindmark-Mansson H., Oredsson S.M., Paulsson M.A. Lactoferricin treatment decreases the rate of cell proliferation of a human colon cancer cell line. J. Dairy Sci. 2009, 92:2477-2484.
    • (2009) J. Dairy Sci. , vol.92 , pp. 2477-2484
    • Freiburghaus, C.1    Janicke, B.2    Lindmark-Mansson, H.3    Oredsson, S.M.4    Paulsson, M.A.5
  • 20
    • 0031845193 scopus 로고    scopus 로고
    • Protective function of proteins and lipids in human milk
    • Hamosh M. Protective function of proteins and lipids in human milk. Biol. Neonate 1998, 74:163-176.
    • (1998) Biol. Neonate , vol.74 , pp. 163-176
    • Hamosh, M.1
  • 22
    • 0020546727 scopus 로고
    • Amino acid sequence restriction in relation to proteolysis
    • Jörnvall H., Persson B. Amino acid sequence restriction in relation to proteolysis. Biosci. Rep. 1983, 3:225-232.
    • (1983) Biosci. Rep. , vol.3 , pp. 225-232
    • Jörnvall, H.1    Persson, B.2
  • 23
    • 32244434196 scopus 로고    scopus 로고
    • Characterization of the human upper gastrointestinal contents under conditions simulating bioavailability/bioequivalence studies
    • Kalantzi L., Goumas K., Kalioras V., Abrahamsson B., Dressman J.B., Reppas C. Characterization of the human upper gastrointestinal contents under conditions simulating bioavailability/bioequivalence studies. Pharm. Res. 2006, 23:165-176.
    • (2006) Pharm. Res. , vol.23 , pp. 165-176
    • Kalantzi, L.1    Goumas, K.2    Kalioras, V.3    Abrahamsson, B.4    Dressman, J.B.5    Reppas, C.6
  • 24
    • 79960060285 scopus 로고    scopus 로고
    • Review of paediatric gastrointestinal physiology data relevant to oral drug delivery
    • Kaye J.L. Review of paediatric gastrointestinal physiology data relevant to oral drug delivery. Int. J. Clin. Pharm. 2011, 33:20-24.
    • (2011) Int. J. Clin. Pharm. , vol.33 , pp. 20-24
    • Kaye, J.L.1
  • 25
    • 20944443596 scopus 로고    scopus 로고
    • Human pancreatic exocrine response to nutrients in health and disease
    • 10.1136/gut.2005.065946
    • Keller J., Layer P. Human pancreatic exocrine response to nutrients in health and disease. Gut 2005, 54:1-28. 10.1136/gut.2005.065946.
    • (2005) Gut , vol.54 , pp. 1-28
    • Keller, J.1    Layer, P.2
  • 26
    • 0034673322 scopus 로고    scopus 로고
    • Antimicrobial peptide of Korean native goat lactoferrin and identification of the part essential for this activity
    • Kimura M., Nam M.S., Ohkouchi Y., Kumura H., Shimazaki K., Yu D.Y. Antimicrobial peptide of Korean native goat lactoferrin and identification of the part essential for this activity. Biochem. Biophys. Res. Commun. 2000, 268:333-336.
    • (2000) Biochem. Biophys. Res. Commun. , vol.268 , pp. 333-336
    • Kimura, M.1    Nam, M.S.2    Ohkouchi, Y.3    Kumura, H.4    Shimazaki, K.5    Yu, D.Y.6
  • 27
    • 0034906217 scopus 로고    scopus 로고
    • Functional fragments of ingested lactoferrin are resistant to proteolytic degradation in the gastrointestinal tract of adult rats
    • Kuwata H., Yamauchi K., Teraguchi S., Ushida Y., Shimokawa Y., Toida T., Hayasawa H. Functional fragments of ingested lactoferrin are resistant to proteolytic degradation in the gastrointestinal tract of adult rats. J. Nutr. 2001, 131:2121-2127.
    • (2001) J. Nutr. , vol.131 , pp. 2121-2127
    • Kuwata, H.1    Yamauchi, K.2    Teraguchi, S.3    Ushida, Y.4    Shimokawa, Y.5    Toida, T.6    Hayasawa, H.7
  • 28
    • 0032437146 scopus 로고    scopus 로고
    • Direct evidence of the generation in human stomach of an antimicrobial peptide domain (lactoferricin) from ingested lactoferrin
    • a
    • Kuwata H., Yip T.T., Tomita M., Hutchens T.W. Direct evidence of the generation in human stomach of an antimicrobial peptide domain (lactoferricin) from ingested lactoferrin. Biochim. Biophys. Acta 1998, 1429:129-141. a.
    • (1998) Biochim. Biophys. Acta , vol.1429 , pp. 129-141
    • Kuwata, H.1    Yip, T.T.2    Tomita, M.3    Hutchens, T.W.4
  • 30
    • 0014949207 scopus 로고
    • Cleavage of structural proteins during assembly of head of bacteriophage-T4
    • Laemmli U.K. Cleavage of structural proteins during assembly of head of bacteriophage-T4. Nature 1970, 227:680-685.
    • (1970) Nature , vol.227 , pp. 680-685
    • Laemmli, U.K.1
  • 31
    • 0029126185 scopus 로고
    • Lactoferrin-A general review
    • Levay P.F., Viljoen M. Lactoferrin-A general review. Haematologica 1995, 80:252-267.
    • (1995) Haematologica , vol.80 , pp. 252-267
    • Levay, P.F.1    Viljoen, M.2
  • 33
    • 67649939005 scopus 로고    scopus 로고
    • Emulsification alters simulated gastrointestinal proteolysis of β-casein and β-lactoglobulin
    • Macierzanka A., Sancho A.I., Mills E.N.C., Rigby N.M., Mackie A.R. Emulsification alters simulated gastrointestinal proteolysis of β-casein and β-lactoglobulin. Soft Matter 2009, 5:538-550.
    • (2009) Soft Matter , vol.5 , pp. 538-550
    • Macierzanka, A.1    Sancho, A.I.2    Mills, E.N.C.3    Rigby, N.M.4    Mackie, A.R.5
  • 34
    • 1442286045 scopus 로고    scopus 로고
    • Proline versus charge concept for protein stabilization against proteolytic attack
    • Markert Y., Koditz J., Ulbrich-Hofmann R., Arnold U. Proline versus charge concept for protein stabilization against proteolytic attack. Protein Eng. 2003, 16:1041-1046.
    • (2003) Protein Eng. , vol.16 , pp. 1041-1046
    • Markert, Y.1    Koditz, J.2    Ulbrich-Hofmann, R.3    Arnold, U.4
  • 35
    • 49349095143 scopus 로고    scopus 로고
    • Bovine lactoferrin supplementation supports immune and antioxidant status in healthy human males
    • Mulder A.M., Connellan P.A., Oliver C.J., Morris C.A., Stevenson L.M. Bovine lactoferrin supplementation supports immune and antioxidant status in healthy human males. Nutr. Res. 2008, 28:583-589.
    • (2008) Nutr. Res. , vol.28 , pp. 583-589
    • Mulder, A.M.1    Connellan, P.A.2    Oliver, C.J.3    Morris, C.A.4    Stevenson, L.M.5
  • 36
    • 3342928851 scopus 로고    scopus 로고
    • The antimicrobial activity of lactoferrin: Current status and perspectives
    • Orsi N. The antimicrobial activity of lactoferrin: Current status and perspectives. Biometals 2004, 17:189-196.
    • (2004) Biometals , vol.17 , pp. 189-196
    • Orsi, N.1
  • 37
    • 0033009966 scopus 로고    scopus 로고
    • Two ion-exchange chromatographic methods for the isolation of antibacterial peptides from lactoferrin. In situ enzymatic hydrolysis on an ion-exchange membrane
    • Recio I., Visser S. Two ion-exchange chromatographic methods for the isolation of antibacterial peptides from lactoferrin. In situ enzymatic hydrolysis on an ion-exchange membrane. J. Chromatogr. A 1999, 831:191-201.
    • (1999) J. Chromatogr. A , vol.831 , pp. 191-201
    • Recio, I.1    Visser, S.2
  • 38
    • 0034488923 scopus 로고    scopus 로고
    • Antibacterial and binding characteristics of bovine, ovine and caprine lactoferrins: A comparative study
    • Recio I., Visser S. Antibacterial and binding characteristics of bovine, ovine and caprine lactoferrins: A comparative study. Int. Dairy J. 2000, 10:597-605.
    • (2000) Int. Dairy J. , vol.10 , pp. 597-605
    • Recio, I.1    Visser, S.2
  • 39
    • 33747597566 scopus 로고    scopus 로고
    • Review article: Human pepsins-Their multiplicity, function and role in reflux disease
    • Roberts N.B. Review article: Human pepsins-Their multiplicity, function and role in reflux disease. Aliment. Pharmacol. Ther. 2006, 24:2-9.
    • (2006) Aliment. Pharmacol. Ther. , vol.24 , pp. 2-9
    • Roberts, N.B.1
  • 41
    • 0019353008 scopus 로고
    • Characterization of human exocrine pancreatic proteins by two-dimensional isoelectric focusing/sodium dodecyl sulfate gel electrophoresis
    • Scheele G., Bartelt D., Bieger W. Characterization of human exocrine pancreatic proteins by two-dimensional isoelectric focusing/sodium dodecyl sulfate gel electrophoresis. Gastroenterology 1981, 80:461-473.
    • (1981) Gastroenterology , vol.80 , pp. 461-473
    • Scheele, G.1    Bartelt, D.2    Bieger, W.3
  • 43
    • 0242637115 scopus 로고    scopus 로고
    • Cathelicidin family of antimicrobial peptides: Proteolytic processing and protease resistance
    • Shinnar A.E., Butler K.L., Park H.J. Cathelicidin family of antimicrobial peptides: Proteolytic processing and protease resistance. Bioorg. Chem. 2003, 31:425-436.
    • (2003) Bioorg. Chem. , vol.31 , pp. 425-436
    • Shinnar, A.E.1    Butler, K.L.2    Park, H.J.3
  • 44
    • 78349309161 scopus 로고    scopus 로고
    • Structural characteristic, pH and thermal stabilities of apo and holo forms of caprine and bovine lactoferrins
    • Sreedhara A., Flengsrud R., Langsrud T., Kaul P., Prakash V., Vegarud G.E. Structural characteristic, pH and thermal stabilities of apo and holo forms of caprine and bovine lactoferrins. Biometals 2010, 23:1159-1170.
    • (2010) Biometals , vol.23 , pp. 1159-1170
    • Sreedhara, A.1    Flengsrud, R.2    Langsrud, T.3    Kaul, P.4    Prakash, V.5    Vegarud, G.E.6
  • 46
    • 0036714306 scopus 로고    scopus 로고
    • Orally ingested human lactoferrin is digested and secreted in the upper gastrointestinal tract in vivo in women with ileostomies
    • Troost F.J., Saris W.H.M., Brummer R.J.M. Orally ingested human lactoferrin is digested and secreted in the upper gastrointestinal tract in vivo in women with ileostomies. J. Nutr. 2002, 132:2597-2600.
    • (2002) J. Nutr. , vol.132 , pp. 2597-2600
    • Troost, F.J.1    Saris, W.H.M.2    Brummer, R.J.M.3
  • 47
    • 0034894840 scopus 로고    scopus 로고
    • Gastric digestion of bovine lactoferrin in vivo in adults
    • Troost F.J., Steijns J., Saris W.H., Brummer R.J. Gastric digestion of bovine lactoferrin in vivo in adults. J. Nutr. 2001, 131:2101-2104.
    • (2001) J. Nutr. , vol.131 , pp. 2101-2104
    • Troost, F.J.1    Steijns, J.2    Saris, W.H.3    Brummer, R.J.4
  • 48
    • 84856200765 scopus 로고    scopus 로고
    • Human gastrointestinal juices intended for use in in vitro digestion models
    • Ulleberg E.K., Comi I., Holm H., Herud E., Jacobsen M., Vegarud G. Human gastrointestinal juices intended for use in in vitro digestion models. Food Dig. 2011, 2:52-61.
    • (2011) Food Dig. , vol.2 , pp. 52-61
    • Ulleberg, E.K.1    Comi, I.2    Holm, H.3    Herud, E.4    Jacobsen, M.5    Vegarud, G.6
  • 50
    • 65449188232 scopus 로고    scopus 로고
    • Jalview Version 2-A multiple sequence alignment editor and analysis workbench
    • Waterhouse A.M., Procter J.B., Martin D.M., Clamp M., Barton G.J. Jalview Version 2-A multiple sequence alignment editor and analysis workbench. Bioinformatics 2009, 25:1189-1191.
    • (2009) Bioinformatics , vol.25 , pp. 1189-1191
    • Waterhouse, A.M.1    Procter, J.B.2    Martin, D.M.3    Clamp, M.4    Barton, G.J.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.