Effects of transient cerebral ischemia on the expression of DNA methyltransferase 1 in the gerbil hippocampal CA1 region

Neurochemical Research

Volumn 38, Issue 1, 2013, Pages 74-81

  Lee, Jae Chul ^a   Park, Joon Ha ^a   Yan, Bing Chun ^a   Kim, In Hye ^a   Cho, Geum Sil ^b   Jeoung, Dooil ^a   Kwon, Young Geun ^c   Kim, Young Myeong ^a   Lee, Yun Lyul ^d   Shin, Hyung Cheul ^d   Won, Moo Ho ^a  

^a Kangwon National University   (South Korea)

^b Korea University College of Medicine   (South Korea)

^c Yonsei University   (South Korea)

^d Hallym University   (South Korea)

Author keywords

Delayed neuronal death; DNA methyltransferases 1; GABAergic neurons; Hippocampus; Ischemic damage; Pyramidal neurons

Indexed keywords

DNA METHYLTRANSFERASE 1; NEURON SPECIFIC NUCLEAR PROTEIN;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; ASTROCYTE; BRAIN LEVEL; BRAIN NERVE CELL; CELL DEATH; CONTROLLED STUDY; GABAERGIC SYSTEM; GERBIL; HIPPOCAMPAL CA1 REGION; IMMUNOREACTIVITY; INTERNEURON; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PYRAMIDAL NERVE CELL; STRATUM PYRAMIDALE; TRANSIENT ISCHEMIC ATTACK;

ANIMALS; ASTROCYTES; BLOTTING, WESTERN; CA1 REGION, HIPPOCAMPAL; CELL DEATH; DNA (CYTOSINE-5-)-METHYLTRANSFERASE; FLUORESCEINS; FLUORESCENT ANTIBODY TECHNIQUE, INDIRECT; FLUORESCENT DYES; GERBILLINAE; IMMUNOHISTOCHEMISTRY; INTERNEURONS; ISCHEMIC ATTACK, TRANSIENT; MALE; PYRAMIDAL CELLS;

GERBILLINAE;

EID: 84871623734     PISSN: 03643190     EISSN: 15736903     Source Type: Journal    
DOI: 10.1007/s11064-012-0890-2     Document Type: Article

References (35)

1. Kirino T (1982) Delayed neuronal death in the gerbil hippocampus following ischemia. Brain Res 239:57-69
2. Hwang IK, Yoo KY, Suh HW et al (2008) Folic acid deficiency increases delayed neuronal death, DNA damage, platelet endothelial cell adhesion molecule-1 immunoreactivity, and gliosis in the hippocampus after transient cerebral ischemia. J Neurosci Res 86:2003-2015
3. Lee CH, Park JH, Yoo KY et al (2011) Pre- and post-treatments with escitalopram protect against experimental ischemic neuronal damage via regulation of BDNF expression and oxidative stress. Exp Neurol 229:450-459
4. Jaenisch R (1997) DNA methylation and imprinting: why bother? Trends Genet 13:323-329
5. Robertson KD, Wolffe AP (2000) DNA methylation in health and disease. Nat Rev Genet 1:11-19
6. Bird A (1992) The essentials of DNA methylation. Cell 70:5-8
7. Laird PW, Jaenisch R (1996) The role of DNA methylation in cancer genetic and epigenetics. Annu Rev Genet 30:441-464
8. Brooks PJ, Marietta C, Goldman D (1996) DNA mismatch repair and DNA methylation in adult brain neurons. J Neurosci 16:939-945
9. Fan G, Beard C, Chen RZ et al (2001) DNA hypomethylation perturbs the function and survival of CNS neurons in postnatal animals. J Neurosci 21:788-797
10. Levenson JM, Roth TL, Lubin FD et al (2006) Evidence that DNA (cytosine-5) methyltransferase regulates synaptic plasticity in the hippocampus. J Biol Chem 281:15763-15773
11. Bestor T, Laudano A, Mattaliano R et al (1988) Cloning and sequencing of a cDNA encoding DNA methyltransferase of mouse cells. The carboxyl-terminal domain of the mammalian enzymes is related to bacterial restriction methyltransferases. J Mol Biol 203:971-983
12. Veldic M, Caruncho HJ, Liu WS et al (2004) DNA-methyltransferase 1 mRNA is selectively overexpressed in telencephalic GABAergic interneurons of schizophrenia brains. Proc Natl Acad Sci USA 101:348-353
13. Inano K, Suetake I, Ueda T et al (2000) Maintenance-type DNA methyltransferase is highly expressed in post-mitotic neurons and localized in the cytoplasmic compartment. J Biochem 128:315-321
14. Miller CA, Sweatt JD (2007) Covalent modification of DNA regulates memory formation. Neuron 53:857-869
15. LaPlant Q, Vialou V, Covington HE 3rd et al (2010) Dnmt3a regulates emotional behavior and spine plasticity in the nucleus accumbens. Nat Neurosci 13:1137-1143
16. Endres M, Fan G, Meisel A et al (2001) Effects of cerebral ischemia in mice lacking DNA methyltransferase 1 in post-mitotic neurons. NeuroReport 12:3763-3766
17. Endres M, Meisel A, Biniszkiewicz D et al (2000) DNA methyltransferase contributes to delayed ischemic brain injury. J Neurosci 20:3175-3181
18. Hu Z, Zeng L, Xie L et al (2007) Morphological alteration of Golgi apparatus and subcellular compartmentalization of TGF-beta1 in Golgi apparatus in gerbils following transient forebrain ischemia. Neurochem Res 32:1927-1931
19. Ji X, Li C, Lu Y et al (2007) Post-ischemic continuous administration of galantamine attenuates cognitive deficits and hippocampal neurons loss after transient global ischemia in gerbils. Neurosci Lett 416:92-95
20. Shelat PB, Coulibaly AP, Wang Q et al (2006) Ischemia-induced increase in RGS7 mRNA expression in gerbil hippocampus. Neurosci Lett 403:157-161
21. Lee CH, Moon SM, Yoo KY et al (2010) Long-term changes in neuronal degeneration and microglial activation in the hippocampal CA1 region after experimental transient cerebral ischemic damage. Brain Res 1342:138-149
22. Schmued LC, Hopkins KJ (2000) Fluoro-Jade B: a high affinity fluorescent marker for the localization of neuronal degeneration. Brain Res 874:123-130
23. Lee CH, Moon SM, Yoo KY et al (2010) Long-term changes in neuronal degeneration and microglial activation in the hippocampal CA1 region after experimental transient cerebral ischemic damage. Brain Res 1342:138-149
24. Liu PK, Hsu CY, Dizdaroglu M et al (1996) Damage, repair, and mutagenesis in nuclear genes after mouse forebrain ischemia-reperfusion. J Neurosci 16:6795-6806
25. MacManus JP, Linnik MD (1997) Gene expression induced by cerebral ischemia: an apoptotic perspective. J Cereb Blood Flow Metab 17:815-832
26. Cui J, Holmes EH, Liu PK (1999) Oxidative damage to the c-fos gene and reduction of its transcription after focal cerebral ischemia. J Neurochem 73:1164-1174
27. Noh JS, Sharma RP, Veldic M et al (2005) DNA methyltransferase 1 regulates reelin mRNA expression in mouse primary cortical cultures. Proc Natl Acad Sci USA 102:1749-1754
28. Chestnut BA, Chang Q, Price A et al (2011) Epigenetic regulation of motor neuron cell death through DNA methylation. J Neurosci 31:16619-16636
29. Cerda S, Weitzman SA (1997) Influence of oxygen radical injury on DNA methylation. Mutat Res 386:141-152
30. Won MH, Kang TC, Jeon GS et al (1999) Immunohistochemical detection of oxidative DNA damage induced by ischemia-reperfusion insults in gerbil hippocampus in vivo. Brain Res 836:70-78
31. Lundberg J, Karimi M, von Gertten C et al (2009) Traumatic brain injury induces relocalization of DNA-methyltransferase 1. Neurosci Lett 457:8-11
32. Ruzicka WB, Zhubi A, Veldic M et al (2007) Selective epigenetic alteration of layer I GABAergic neurons isolated from prefrontal cortex of schizophrenia patients using laser-assisted microdissection. Mol Psychiatr 12:385-397
33. Fan G, Martinowich K, Chin MH et al (2005) DNA methylation controls the timing of astrogliogenesis through regulation of JAK-STAT signaling. Development 132:3345-3356
34. Liu Y, Ford B, Mann MA et al (2001) Neuregulins increase alpha7 nicotinic acetylcholine receptors and enhance excitatory synaptic transmission in GABAergic interneurons of the hippocampus. J Neurosci 21:5660-5669
35. Fukuda T, Nakano S, Yoshiya I et al (1993) Persistent degenerative state of non-pyramidal neurons in the CA1 region of the gerbil hippocampus following transient forebrain ischemia. Neuroscience 53:23-38