-
1
-
-
79954486763
-
Regulatory T cells and Foxp3
-
Rudensky AY. Regulatory T cells and Foxp3. Immunol Rev. 2011;241:260-268.
-
(2011)
Immunol Rev
, vol.241
, pp. 260-268
-
-
Rudensky, A.Y.1
-
2
-
-
0035167967
-
The immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome (IPEX) is caused by mutations of FOXP3
-
Bennett CL, Christie J, Ramsdell F, et al. The immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome (IPEX) is caused by mutations of FOXP3. Nat Genet. 2001;27:20-21.
-
(2001)
Nat Genet
, vol.27
, pp. 20-21
-
-
Bennett, C.L.1
Christie, J.2
Ramsdell, F.3
-
3
-
-
0035162560
-
Disruption of a new forkhead/winged-helix protein, scurfin, results in the fatal lymphoproliferative disorder of the scurfy mouse
-
Brunkow ME, Jeffery EW, Hjerrild KA, et al. Disruption of a new forkhead/winged-helix protein, scurfin, results in the fatal lymphoproliferative disorder of the scurfy mouse. Nat Genet. 2001;27:68-73.
-
(2001)
Nat Genet
, vol.27
, pp. 68-73
-
-
Brunkow, M.E.1
Jeffery, E.W.2
Hjerrild, K.A.3
-
4
-
-
0035141865
-
Escape from tolerance in the human X-linked autoimmunity-allergic disregulation syndrome and the Scurfy mouse
-
Patel DD. Escape from tolerance in the human X-linked autoimmunity-allergic disregulation syndrome and the Scurfy mouse. J Clin Invest. 2001;107:155-157.
-
(2001)
J Clin Invest
, vol.107
, pp. 155-157
-
-
Patel, D.D.1
-
5
-
-
0035163909
-
X-linked neonatal diabetes mellitus, enteropathy and endocrinopathy syndrome is the human equivalent of mouse scurfy
-
Wildin RS, Ramsdell F, Peake J, et al. X-linked neonatal diabetes mellitus, enteropathy and endocrinopathy syndrome is the human equivalent of mouse scurfy. Nat Genet. 2001;27:18-20.
-
(2001)
Nat Genet
, vol.27
, pp. 18-20
-
-
Wildin, R.S.1
Ramsdell, F.2
Peake, J.3
-
6
-
-
4344682025
-
CD4+ CD25bright T cells in human intestinal lamina propria as regulatory cells
-
Makita S, Kanai T, Oshima S, Uraushihara K, et al. CD4+ CD25bright T cells in human intestinal lamina propria as regulatory cells. J Immunol. 2004;173:3119-3130.
-
(2004)
J Immunol
, vol.173
, pp. 3119-3130
-
-
Makita, S.1
Kanai, T.2
Oshima, S.3
Uraushihara, K.4
-
7
-
-
20444434616
-
Peripheral and intestinal regulatory CD4+ CD25(high) T cells in inflammatory bowel disease
-
Maul J, Loddenkemper C, Mundt P, et al. Peripheral and intestinal regulatory CD4+ CD25(high) T cells in inflammatory bowel disease. Gastroenterology. 2005;128:1868-1878.
-
(2005)
Gastroenterology
, vol.128
, pp. 1868-1878
-
-
Maul, J.1
Loddenkemper, C.2
Mundt, P.3
-
8
-
-
36249014365
-
Characterization of FOXP3+ CD4+ regulatory T cells in Crohn's disease
-
Saruta M, Yu QT, Fleshner PR, et al. Characterization of FOXP3+ CD4+ regulatory T cells in Crohn's disease. Clin Immunol. 2007;125:281-290.
-
(2007)
Clin Immunol
, vol.125
, pp. 281-290
-
-
Saruta, M.1
Yu, Q.T.2
Fleshner, P.R.3
-
9
-
-
33750375612
-
Characterization of Foxp3+ CD4+ CD25+ and IL-10-secreting CD4+ CD25+ T cells during cure of colitis
-
Uhlig HH, Coombes J, Mottet C, et al. Characterization of Foxp3+ CD4+ CD25+ and IL-10-secreting CD4+ CD25+ T cells during cure of colitis. J Immunol. 2006;177:5852-5860.
-
(2006)
J Immunol
, vol.177
, pp. 5852-5860
-
-
Uhlig, H.H.1
Coombes, J.2
Mottet, C.3
-
10
-
-
27644449311
-
The role of 2 FOXP3 isoforms in the generation of human CD4+ Tregs
-
Allan SE, Passerini L, Bacchetta R, et al. The role of 2 FOXP3 isoforms in the generation of human CD4+ Tregs. J Clin Invest. 2005;115:3276-3284.
-
(2005)
J Clin Invest
, vol.115
, pp. 3276-3284
-
-
Allan, S.E.1
Passerini, L.2
Bacchetta, R.3
-
11
-
-
67749130955
-
Absence of leucine zipper in the natural FOXP3Delta2Delta7 isoform does not affect dimerization but abrogates suppressive capacity
-
Mailer RK, Falk K, Rotzschke O. Absence of leucine zipper in the natural FOXP3Delta2Delta7 isoform does not affect dimerization but abrogates suppressive capacity. PLoS One. 2009;4:e6104.
-
(2009)
PLoS One
, vol.4
-
-
Mailer, R.K.1
Falk, K.2
Rotzschke, O.3
-
12
-
-
18244378309
-
Novel mutations of FOXP3 in two Japanese patients with immune dysregulation, polyendocrinopathy, enteropathy, X linked syndrome (IPEX)
-
Kobayashi I, Shiari R, Yamada M, et al. Novel mutations of FOXP3 in two Japanese patients with immune dysregulation, polyendocrinopathy, enteropathy, X linked syndrome (IPEX). J Med Genet. 2001;38:874-876.
-
(2001)
J Med Genet
, vol.38
, pp. 874-876
-
-
Kobayashi, I.1
Shiari, R.2
Yamada, M.3
-
13
-
-
34948875308
-
Immune dysregulation, polyendocrinopathy, enteropathy, X-linked: Forkhead box protein 3 mutations and lack of regulatory T cells
-
Torgerson TR, Ochs HD. Immune dysregulation, polyendocrinopathy, enteropathy, X-linked: forkhead box protein 3 mutations and lack of regulatory T cells. J Allergy Clin Immunol. 2007;120:744-750.
-
(2007)
J Allergy Clin Immunol
, vol.120
, pp. 744-750
-
-
Torgerson, T.R.1
Ochs, H.D.2
-
14
-
-
56749151293
-
Th17 cells in immunity and autoimmunity
-
Oukka M. Th17 cells in immunity and autoimmunity. Ann Rheum Dis. 2008;67:iii26-iii29.
-
(2008)
Ann Rheum Dis
, vol.67
-
-
Oukka, M.1
-
15
-
-
34547734621
-
Phenotypic and functional features of human Th17 cells
-
Annunziata F, Cosmi L, Santarlasci V, et al. Phenotypic and functional features of human Th17 cells. J Exp Med. 2007;204:1849-1861.
-
(2007)
J Exp Med
, vol.204
, pp. 1849-1861
-
-
Annunziata, F.1
Cosmi, L.2
Santarlasci, V.3
-
16
-
-
1642369092
-
Interleukin-17: A mediator of inflammatory responses
-
Witowski J, Ksiazek K, Jorres A. Interleukin-17: a mediator of inflammatory responses. Cell Mol Life Sci. 2004;61:567-579.
-
(2004)
Cell Mol Life Sci
, vol.61
, pp. 567-579
-
-
Witowski, J.1
Ksiazek, K.2
Jorres, A.3
-
17
-
-
32244442562
-
TGFbeta in the context of an inflammatory cytokine milieu supports de novo differentiation of IL-17-producing T cells
-
Veldhoen M, Hocking RJ, Atkins CJ, Locksley RM, Stockinger B. TGFbeta in the context of an inflammatory cytokine milieu supports de novo differentiation of IL-17-producing T cells. Immunity. 2006;24:179-189.
-
(2006)
Immunity
, vol.24
, pp. 179-189
-
-
Veldhoen, M.1
Hocking, R.J.2
Atkins, C.J.3
Locksley, R.M.4
Stockinger, B.5
-
18
-
-
34249030920
-
IL-23 receptor (IL-23R) gene protects against pediatric Crohn's disease
-
Dubinsky MC, Wang D, Picornell Y, et al. IL-23 receptor (IL-23R) gene protects against pediatric Crohn's disease. Inflamm Bowel Dis. 2007;13:511-515.
-
(2007)
Inflamm Bowel Dis
, vol.13
, pp. 511-515
-
-
Dubinsky, M.C.1
Wang, D.2
Picornell, Y.3
-
19
-
-
33845340501
-
A genome-wide association study identifies IL23R as an inflammatory bowel disease gene
-
Duerr RH, Taylor KD, Brant SR, et al. A genome-wide association study identifies IL23R as an inflammatory bowel disease gene. Science. 2006;314:1461-1463.
-
(2006)
Science
, vol.314
, pp. 1461-1463
-
-
Duerr, R.H.1
Taylor, K.D.2
Brant, S.R.3
-
20
-
-
78649489009
-
Genome-wide metaanalysis increases to 71 the number of confirmed Crohn's disease susceptibility loci
-
Franke A, McGovern DP, Barrett JC, et al. Genome-wide metaanalysis increases to 71 the number of confirmed Crohn's disease susceptibility loci. Nat Genet. 2010;42:1118-1125.
-
(2010)
Nat Genet
, vol.42
, pp. 1118-1125
-
-
Franke, A.1
McGovern, D.P.2
Barrett, J.C.3
-
21
-
-
53049091561
-
A randomized trial of Ustekinumab, a human interleukin-12/23 monoclonal antibody, in patients with moderate-to-severe Crohn's disease
-
Sandborn WJ, Feagan BG, Fedorak RN, et al. A randomized trial of Ustekinumab, a human interleukin-12/23 monoclonal antibody, in patients with moderate-to-severe Crohn's disease. Gastroenterology. 2008;135:1130-1141.
-
(2008)
Gastroenterology
, vol.135
, pp. 1130-1141
-
-
Sandborn, W.J.1
Feagan, B.G.2
Fedorak, R.N.3
-
22
-
-
33646577466
-
Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells
-
Bettelli E, Carrier Y, Gao W, et al. Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells. Nature. 2006;441:235-238.
-
(2006)
Nature
, vol.441
, pp. 235-238
-
-
Bettelli, E.1
Carrier, Y.2
Gao, W.3
-
23
-
-
0027447515
-
Cytokine mRNA expression in intestine from normal and inflammatory bowel disease patients
-
McCabe RP, Secrist H, Botney M, Egan M, Peters MG. Cytokine mRNA expression in intestine from normal and inflammatory bowel disease patients. Clin Immunol Immunopathol. 1993;66: 52-58.
-
(1993)
Clin Immunol Immunopathol.
, vol.66
, pp. 52-58
-
-
McCabe, R.P.1
Secrist, H.2
Botney, M.3
Egan, M.4
Peters, M.G.5
-
24
-
-
79952300978
-
Characterization of interleukin-17-producing regulatory T cells in inflamed intestinal mucosa from patients with inflammatory bowel diseases
-
Hovhannisyan Z, Treatman J, Littman DR, Mayer L. Characterization of interleukin-17-producing regulatory T cells in inflamed intestinal mucosa from patients with inflammatory bowel diseases. Gastroenterology. 2011;140:957-965.
-
(2011)
Gastroenterology
, vol.140
, pp. 957-965
-
-
Hovhannisyan, Z.1
Treatman, J.2
Littman, D.R.3
Mayer, L.4
-
25
-
-
33748588423
-
The orphan nuclear receptor RORgammat directs the differentiation programof proinflammatory IL-17+ T helper cells
-
Ivanov II, McKenzie BS, Zhou L, et al. The orphan nuclear receptor RORgammat directs the differentiation programof proinflammatory IL-17+ T helper cells. Cell. 2006;126:1121-1133.
-
(2006)
Cell
, vol.126
, pp. 1121-1133
-
-
Ivanov, I.I.1
McKenzie, B.S.2
Zhou, L.3
-
26
-
-
47749124186
-
Foxp3 inhibits RORgammat-mediated IL-17A mRNA transcription through direct interaction with RORgammat
-
Ichiyama K, Yoshida H, Wakabayashi Y, et al. Foxp3 inhibits RORgammat-mediated IL-17A mRNA transcription through direct interaction with RORgammat. J Biol Chem. 2008;283: 17003-17008.
-
(2008)
J Biol Chem.
, vol.283
, pp. 17003-17008
-
-
Ichiyama, K.1
Yoshida, H.2
Wakabayashi, Y.3
-
27
-
-
43449135305
-
TGF-beta-induced Foxp3 inhibits T(H)17 cell differentiation by antagonizing RORgammat function
-
Zhou L, Lopes JE, Chong MM, et al. TGF-beta-induced Foxp3 inhibits T(H)17 cell differentiation by antagonizing RORgammat function. Nature. 2008;453:236-240.
-
(2008)
Nature
, vol.453
, pp. 236-240
-
-
Zhou, L.1
Lopes, J.E.2
Chong, M.M.3
-
28
-
-
66649115650
-
Human memory FOXP3+ Tregs secrete IL-17 ex vivo and constitutively express the T(H)17 lineage-specific transcription factor RORgamma t
-
Ayyoub M, Deknuydt F, Raimbaud I, et al. Human memory FOXP3+ Tregs secrete IL-17 ex vivo and constitutively express the T(H)17 lineage-specific transcription factor RORgamma t. Proc Natl Acad Sci U S A. 2009;106:8635-8640.
-
(2009)
Proc Natl Acad Sci U S A
, vol.106
, pp. 8635-8640
-
-
Ayyoub, M.1
Deknuydt, F.2
Raimbaud, I.3
-
29
-
-
63849183918
-
Identification of IL-17-producing FOXP3+ regulatory T cells in humans
-
Voo KS, Wang YH, Santori FR, et al. Identification of IL-17-producing FOXP3+ regulatory T cells in humans. Proc Natl Acad Sci U S A. 2009;106:4793-4798.
-
(2009)
Proc Natl Acad Sci U S A
, vol.106
, pp. 4793-4798
-
-
Voo, K.S.1
Wang, Y.H.2
Santori, F.R.3
-
30
-
-
34249309861
-
Expression and functional characterization of FOXP3+ CD4+ regulatory T cells in ulcerative colitis
-
Yu QT, Saruta M, Avanesyan A, Fleshner PR, Banham AH, Papadakis KA. Expression and functional characterization of FOXP3+ CD4+ regulatory T cells in ulcerative colitis. Inflamm Bowel Dis. 2007;13:191-199.
-
(2007)
Inflamm Bowel Dis
, vol.13
, pp. 191-199
-
-
Yu, Q.T.1
Saruta, M.2
Avanesyan, A.3
Fleshner, P.R.4
Banham, A.H.5
Papadakis, K.A.6
|