AL Amyloid Imaging and Therapy with a Monoclonal Antibody to a Cryptic Epitope on Amyloid Fibrils

PLoS ONE

Volumn 7, Issue 12, 2012, Pages

  Wall, Jonathan S ^a   Kennel, Stephen J ^a   Williams, Angela ^a   Richey, Tina ^a   Stuckey, Alan ^a   Huang, Ying ^a   Macy, Sallie ^a   Donnell, Robert ^b   Barbour, Robin ^c   Seubert, Peter ^c   Schenk, Dale ^c  

^a UNIVERSITY OF TENNESSEE GRADUATE SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF TENNESSEE   (United States)

^c Neotope Biosciences   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMYLOID; AMYLOID A PROTEIN; ANTIGEN; ASPARTIC ACID; CRYPTIC EPITOPE; EPITOPE; GLUTAMIC ACID; IODINE 131; MONOCLONAL ANTIBODY; MONOCLONAL ANTIBODY 2A4; MONOCLONAL ANTIBODY 2A4 I 131; UNCLASSIFIED DRUG;

AMYLOIDOSIS; ANIMAL EXPERIMENT; ANTIGEN BINDING; ARTICLE; BINDING AFFINITY; CONCENTRATION RESPONSE; CONTROLLED STUDY; HUMAN; HUMAN TISSUE; IMMUNOGLOBULIN LIGHT CHAIN AMYLOIDOSIS; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; IN VIVO STUDY; ISOTOPE LABELING; LIGHT CHAIN; MACROPHAGE; MOUSE; NEUTROPHIL; NONHUMAN; PROTEIN LOCALIZATION; SINGLE PHOTON EMISSION COMPUTER TOMOGRAPHY; SURFACE PLASMON RESONANCE; TISSUE DISTRIBUTION;

AMINO ACID SEQUENCE; AMYLOID; AMYLOIDOSIS; ANIMALS; ANTIBODIES, MONOCLONAL, MURINE-DERIVED; ANTIBODY AFFINITY; BENCE JONES PROTEIN; BINDING, COMPETITIVE; EPITOPES; HUMANS; IMMUNOTHERAPY; KIDNEY; LIVER; MICE; MICE, SCID; ORGAN SPECIFICITY; PANCREAS; PEPTIDE FRAGMENTS; PROTEIN BINDING; RADIOPHARMACEUTICALS; TISSUE DISTRIBUTION; TOMOGRAPHY, EMISSION-COMPUTED, SINGLE-PHOTON; WHOLE BODY IMAGING;

ANIMALIA; MUS;

EID: 84871601016     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0052686     Document Type: Article

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