-
1
-
-
66149089601
-
Characterization of UGTs active against SAHA and association between SAHA glucuronidation activity phenotype with UGT genotype
-
Balliet RM, Chen G, Gallagher CJ, Dellinger RW, Sun D, and Lazarus P (2009) Characterization of UGTs active against SAHA and association between SAHA glucuronidation activity phenotype with UGT genotype. Cancer Res 69:2981-2989.
-
(2009)
Cancer Res
, vol.69
, pp. 2981-2989
-
-
Balliet, R.M.1
Chen, G.2
Gallagher, C.J.3
Dellinger, R.W.4
Sun, D.5
Lazarus, P.6
-
2
-
-
34547899883
-
Reverse transcriptase-PCR quantification of mRNA levels from cytochrome (CYP)1, CYP2 and CYP3 families in 22 different human tissues
-
DOI 10.1097/FPC.0b013e32810f2e58, PII 0121301120070900000006
-
Bièche I, Narjoz C, Asselah T, Vacher S, Marcellin P, Lidereau R, Beaune P, and de Waziers I (2007) Reverse transcriptase-PCR quantification of mRNA levels from cytochrome (CYP)1, CYP2 and CYP3 families in 22 different human tissues. Pharmacogenet Genomics 17:731-742. (Pubitemid 47263068)
-
(2007)
Pharmacogenetics and Genomics
, vol.17
, Issue.9
, pp. 731-742
-
-
Bieche, I.1
Narjoz, C.2
Asselah, T.3
Vacher, S.4
Marcellin, P.5
Lidereau, R.6
Beaune, P.7
De Waziers, I.8
-
4
-
-
78751612798
-
Characterization of UDP-glucuronosyltransferase 2A1 (UGT2A1) variants and their potential role in tobacco carcinogenesis
-
Bushey RT, Chen G, Blevins-Primeau AS, Krzeminski J, Amin S, and Lazarus P (2011) Characterization of UDP-glucuronosyltransferase 2A1 (UGT2A1) variants and their potential role in tobacco carcinogenesis. Pharmacogenet Genomics 21:55-65.
-
(2011)
Pharmacogenet Genomics
, vol.21
, pp. 55-65
-
-
Bushey, R.T.1
Chen, G.2
Blevins-Primeau, A.S.3
Krzeminski, J.4
Amin, S.5
Lazarus, P.6
-
5
-
-
84869208721
-
Identification and functional characterization of a novel UGT2A1 splice variant: Potential importance in tobacco-related cancer susceptibility
-
Bushey RT and Lazarus P (2012) Identification and functional characterization of a novel UGT2A1 splice variant: Potential importance in tobacco-related cancer susceptibility. J Pharmacol Exp Ther 343:712-724.
-
(2012)
J Pharmacol Exp Ther
, vol.343
, pp. 712-724
-
-
Bushey, R.T.1
Lazarus, P.2
-
6
-
-
40049105052
-
Identification of a prevalent functional missense polymorphism in the UGT2B10 gene and its association with UGT2B10 inactivation against tobacco-specific nitrosamines
-
Chen G, Dellinger RW, Gallagher CJ, Sun D, and Lazarus P (2008a) Identification of a prevalent functional missense polymorphism in the UGT2B10 gene and its association with UGT2B10 inactivation against tobacco-specific nitrosamines. Pharmacogenet Genomics 18:181- 191.
-
(2008)
Pharmacogenet Genomics
, vol.18
, pp. 181-191
-
-
Chen, G.1
Dellinger, R.W.2
Gallagher, C.J.3
Sun, D.4
Lazarus, P.5
-
7
-
-
42449104914
-
Glucuronidation of tobacco-specific nitrosamines by UGT2B10
-
DOI 10.1124/dmd.107.019406
-
Chen G, Dellinger RW, Sun D, Spratt TE, and Lazarus P (2008b) Glucuronidation of tobacco-specific nitrosamines by UGT2B10. Drug Metab Dispos 36:824-830. (Pubitemid 351574879)
-
(2008)
Drug Metabolism and Disposition
, vol.36
, Issue.5
, pp. 824-830
-
-
Chen, G.1
Dellinger, R.W.2
Sun, D.3
Spratt, T.E.4
Lazarus, P.5
-
8
-
-
50449083633
-
Novel polymorphic human UDP-glucuronosyltransferase 2A3: Cloning, functional characterization of enzyme variants, comparative tissue expression, and gene induction
-
Court MH, Hazarika S, Krishnaswamy S, Finel M, and Williams JA (2008) Novel polymorphic human UDP-glucuronosyltransferase 2A3: cloning, functional characterization of enzyme variants, comparative tissue expression, and gene induction. Mol Pharmacol 74:744-754.
-
(2008)
Mol Pharmacol
, vol.74
, pp. 744-754
-
-
Court, M.H.1
Hazarika, S.2
Krishnaswamy, S.3
Finel, M.4
Williams, J.A.5
-
9
-
-
35549008096
-
Glucuronidation of PhIP and N-OH-PhIP by UDP-glucuronosyltransferase 1A10
-
DOI 10.1093/carcin/bgm164
-
Dellinger RW, Chen G, Blevins-Primeau AS, Krzeminski J, Amin S, and Lazarus P (2007) Glucuronidation of PhIP and N-OH-PhIP by UDP- glucuronosyltransferase 1A10. Carcinogenesis 28:2412-2418. (Pubitemid 350111602)
-
(2007)
Carcinogenesis
, vol.28
, Issue.11
, pp. 2412-2418
-
-
Dellinger, R.W.1
Chen, G.2
Blevins-Primeau, A.S.3
Krzeminski, J.4
Amin, S.5
Lazarus, P.6
-
10
-
-
33646804138
-
139LYS isoform
-
DOI 10.1124/dmd.105.009100
-
Dellinger RW, Fang JL, Chen G, Weinberg R, and Lazarus P (2006) Importance of UDP-glucuronosyltransferase 1A10 (UGT1A10) in the detoxification of polycyclic aromatic hydrocarbons: decreased glucuronidative activity of the UGT1A10139Lys isoform. Drug Metab Dispos 34:943-949. (Pubitemid 43763749)
-
(2006)
Drug Metabolism and Disposition
, vol.34
, Issue.6
, pp. 943-949
-
-
Dellinger, R.W.1
Fang, J.-L.2
Chen, G.3
Weinberg, R.4
Lazarus, P.5
-
11
-
-
0036532140
-
Characterization of benzo(a)pyrene-trans-7,8-dihydrodiol glucuronidation by human tissue microsomes and overexpressed UDP-glucuronosyltransferase enzymes
-
Fang JL, Beland FA, Doerge DR, Wiener D, Guillemette C, Marques MM, and Lazarus P (2002) Characterization of benzo(a)pyrene-trans-7,8-dihydrodiol glucuronidation by human tissue microsomes and overexpressed UDP-glucuronosyltransferase enzymes. Cancer Res 62:1978-1986. (Pubitemid 34408441)
-
(2002)
Cancer Research
, vol.62
, Issue.7
, pp. 1978-1986
-
-
Fang, J.-L.1
Beland, F.A.2
Doerge, D.R.3
Wiener, D.4
Guillemette, C.5
Marques, M.M.6
Lazarus, P.7
-
12
-
-
79959503826
-
The International HapMap Project
-
International HapMap Consortium
-
Gibbs RA; International HapMap Consortium (2003) The International HapMap Project. Nature 426:789-796.
-
(2003)
Nature
, vol.426
, pp. 789-796
-
-
Gibbs, R.A.1
-
13
-
-
0032211978
-
Glucuronidation: A dual control
-
DOI 10.1016/S0306-3623(98)00114-1, PII S0306362398001141
-
Guéraud F and Paris A (1998) Glucuronidation: a dual control. Gen Pharmacol 31:683-688. (Pubitemid 28520043)
-
(1998)
General Pharmacology
, vol.31
, Issue.5
, pp. 683-688
-
-
Gueraud, F.1
Paris, A.2
-
14
-
-
0033591845
-
Tobacco smoke carcinogens and lung cancer
-
Hecht SS (1999) Tobacco smoke carcinogens and lung cancer. J Natl Cancer Inst 91:1194-1210.
-
(1999)
J Natl Cancer Inst
, vol.91
, pp. 1194-1210
-
-
Hecht, S.S.1
-
15
-
-
0033564554
-
Cloning and characterization of a novel human olfactory UDP-glucuronosyltransferase
-
DOI 10.1042/0264-6021:3400837
-
Jedlitschky G, Cassidy AJ, Sales M, Pratt N, and Burchell B (1999) Cloning and characterization of a novel human olfactory UDP- glucuronosyltransferase. Biochem J 340:837-843. (Pubitemid 29312884)
-
(1999)
Biochemical Journal
, vol.340
, Issue.3
, pp. 837-843
-
-
Jedlitschky, G.1
Cassidy, A.J.2
Sales, M.3
Pratt, N.4
Burchell, B.5
-
16
-
-
84865185090
-
Quantification of Hepatic UDP glucuronosyltransferase 1A splice variant expression and correlation of UDP glucuronosyltransferase 1A1 variant expression with glucuronidation activity
-
Jones NR, Sun D, Freeman WM, and Lazarus P (2012) Quantification of Hepatic UDP glucuronosyltransferase 1A splice variant expression and correlation of UDP glucuronosyltransferase 1A1 variant expression with glucuronidation activity. J Pharmacol Exp Ther 342:720-729.
-
(2012)
J Pharmacol Exp Ther
, vol.342
, pp. 720-729
-
-
Jones, N.R.1
Sun, D.2
Freeman, W.M.3
Lazarus, P.4
-
17
-
-
0034896633
-
Expression of the tumor suppressor gene maspin in human pancreatic cancers
-
Maass N, Hojo T, Ueding M, Lüttges J, Klöppel G, Jonat W, and Nagasaki K (2001) Expression of the tumor suppressor gene Maspin in human pancreatic cancers. Clin Cancer Res 7:812-817. (Pubitemid 32708715)
-
(2001)
Clinical Cancer Research
, vol.7
, Issue.4
, pp. 812-817
-
-
Maass, N.1
Hojo, T.2
Ueding, M.3
Luttges, J.4
Kloppel, G.5
Jonat, W.6
Nagasaki, K.7
-
18
-
-
0037298816
-
Glucosidation of hyodeoxycholic acid by UDP-glucuronosyltransferase 2B7
-
DOI 10.1016/S0006-2952(02)01522-8, PII S0006295202015228
-
Mackenzie P, Little JM, and Radominska-Pandya A (2003) Glucosidation of hyodeoxycholic acid by UDP-glucuronosyltransferase 2B7. Biochem Pharmacol 65:417-421. (Pubitemid 36084558)
-
(2003)
Biochemical Pharmacology
, vol.65
, Issue.3
, pp. 417-421
-
-
Mackenzie, P.1
Little, J.M.2
Radominska-Pandya, A.3
-
19
-
-
25144500468
-
Nomenclature update for the mammalian UDP glycosyltransferase (UGT) gene superfamily
-
Mackenzie PI, Bock KW, Burchell B, Guillemette C, Ikushiro S, Iyanagi T, Miners JO, Owens IS, and Nebert DW (2005) Nomenclature update for the mammalian UDP glycosyltransferase (UGT) gene superfamily. Pharmacogenet Genomics 15:677-685. (Pubitemid 41345319)
-
(2005)
Pharmacogenetics and Genomics
, vol.15
, Issue.10
, pp. 677-685
-
-
Mackenzie, P.I.1
Bock, K.W.2
Burchell, B.3
Guillemette, C.4
Ikushiro, S.-I.5
Iyanagi, T.6
Miners, J.O.7
Owens, I.S.8
Nebert, D.W.9
-
20
-
-
79951973325
-
The novel UDP glycosyltransferase 3A2: Cloning, catalytic properties, and tissue distribution
-
MacKenzie PI, Rogers A, Elliot DJ, Chau N, Hulin JA, Miners JO, and Meech R (2011) The novel UDP glycosyltransferase 3A2: cloning, catalytic properties, and tissue distribution. Mol Pharmacol 79:472-478.
-
(2011)
Mol Pharmacol
, vol.79
, pp. 472-478
-
-
MacKenzie, P.I.1
Rogers, A.2
Elliot, D.J.3
Chau, N.4
Hulin, J.A.5
Miners, J.O.6
Meech, R.7
-
21
-
-
61349136990
-
Identification of UDP glycosyltransferase 3A1 as a UDP N-acetylglucosaminyltransferase
-
Mackenzie PI, Rogers A, Treloar J, Jorgensen BR, Miners JO, and Meech R (2008) Identification of UDP glycosyltransferase 3A1 as a UDP N-acetylglucosaminyltransferase. J Biol Chem 283:36205-36210.
-
(2008)
J Biol Chem
, vol.283
, pp. 36205-36210
-
-
Mackenzie, P.I.1
Rogers, A.2
Treloar, J.3
Jorgensen, B.R.4
Miners, J.O.5
Meech, R.6
-
22
-
-
0032147023
-
Determinants of UDP glucuronosyltransferase membrane association and residency in the endoplasmic reticulum
-
DOI 10.1006/abbi.1998.0750
-
Meech R and Mackenzie PI (1998) Determinants of UDP glucuronosyltransferase membrane association and residency in the endoplasmic reticulum. Arch Biochem Biophys 356:77-85. (Pubitemid 28364357)
-
(1998)
Archives of Biochemistry and Biophysics
, vol.356
, Issue.1
, pp. 77-85
-
-
Meech, R.1
MacKenzie, P.I.2
-
23
-
-
74549142010
-
UGT3A: Novel UDP-glycosyltransferases of the UGT superfamily
-
Meech R and Mackenzie PI (2010) UGT3A: novel UDP-glycosyltransferases of the UGT superfamily. Drug Metab Rev 42:45-54.
-
(2010)
Drug Metab Rev
, vol.42
, pp. 45-54
-
-
Meech, R.1
Mackenzie, P.I.2
-
24
-
-
33645120407
-
Uridine diphosphoglucuronosyltransferase pharmacogenetics and cancer
-
Nagar S and Remmel RP (2006) Uridine diphosphoglucuronosyltransferase pharmacogenetics and cancer. Oncogene 25:1659-1672.
-
(2006)
Oncogene
, vol.25
, pp. 1659-1672
-
-
Nagar, S.1
Remmel, R.P.2
-
25
-
-
70349294431
-
Functional characterization of low-prevalence missense polymorphisms in the UDP-glucuronosyltransferase 1A9 gene
-
Olson KC, Dellinger RW, Zhong Q, Sun D, Amin S, Spratt TE, and Lazarus P (2009) Functional characterization of low-prevalence missense polymorphisms in the UDP-glucuronosyltransferase 1A9 gene. Drug Metab Dispos 37:1999-2007.
-
(2009)
Drug Metab Dispos
, vol.37
, pp. 1999-2007
-
-
Olson, K.C.1
Dellinger, R.W.2
Zhong, Q.3
Sun, D.4
Amin, S.5
Spratt, T.E.6
Lazarus, P.7
-
26
-
-
0023989064
-
Improved tools for biological sequence comparison
-
Pearson WR and Lipman DJ (1988) Improved tools for biological sequence comparison. Proc Natl Acad Sci USA 85:2444-2448.
-
(1988)
Proc Natl Acad Sci USA
, vol.85
, pp. 2444-2448
-
-
Pearson, W.R.1
Lipman, D.J.2
-
27
-
-
0033783035
-
O-Glucuronidation of the lung carcinogen 4-(methylnitrosamino)-1- (3-pyridyl)-1-butanol (NNAL) by human UDP-glucuronosyltransferases 2B7 and 1A9
-
Ren Q, Murphy SE, Zheng Z, and Lazarus P (2000) O-Glucuronidation of the lung carcinogen 4-(methylnitrosamino)-1- (3-pyridyl)-1-butanol (NNAL) by human UDP-glucuronosyltransferases 2B7 and 1A9. Drug Metab Dispos 28:1352-1360.
-
(2000)
Drug Metab Dispos
, vol.28
, pp. 1352-1360
-
-
Ren, Q.1
Murphy, S.E.2
Zheng, Z.3
Lazarus, P.4
-
28
-
-
73949103669
-
Human UDP-glucuronosyltransferase UGT2A2: cDNA construction, expression, and functional characterization in comparison with UGT2A1 and UGT2A3
-
Sneitz N, Court MH, Zhang X, Laajanen K, Yee KK, Dalton P, Ding X, and Finel M (2009) Human UDP-glucuronosyltransferase UGT2A2: cDNA construction, expression, and functional characterization in comparison with UGT2A1 and UGT2A3. Pharmacogenet Genomics 19:923-934.
-
(2009)
Pharmacogenet Genomics
, vol.19
, pp. 923-934
-
-
Sneitz, N.1
Court, M.H.2
Zhang, X.3
Laajanen, K.4
Yee, K.K.5
Dalton, P.6
Ding, X.7
Finel, M.8
-
29
-
-
34748901348
-
Glucuronidation of active tamoxifen metabolites by the human UDP glucuronosyltransferases
-
DOI 10.1124/dmd.107.017145
-
Sun D, Sharma AK, Dellinger RW, Blevins-Primeau AS, Balliet RM, Chen G, Boyiri T, Amin S, and Lazarus P (2007) Glucuronidation of active tamoxifen metabolites by the human UDP glucuronosyltransferases. Drug Metab Dispos 35:2006-2014. (Pubitemid 350010805)
-
(2007)
Drug Metabolism and Disposition
, vol.35
, Issue.11
, pp. 2006-2014
-
-
Sun, D.1
Sharma, A.K.2
Dellinger, R.W.3
Blevins-Primeau, A.S.4
Balliet, R.M.5
Chen, G.6
Boyiri, T.7
Amin, S.8
Lazarus, P.9
-
30
-
-
0025284207
-
UDP-glucuronosyltransferases: A family of detoxifying enzymes
-
DOI 10.1016/0165-6147(90)90008-V
-
Tephly TR and Burchell B (1990) UDP-glucuronosyltransferases: a family of detoxifying enzymes. Trends Pharmacol Sci 11:276-279. (Pubitemid 20205384)
-
(1990)
Trends in Pharmacological Sciences
, vol.11
, Issue.7
, pp. 276-279
-
-
Tephly, T.R.1
Burchell, B.2
-
31
-
-
1842536833
-
Human UDP-glucuronosyltransferases: Isoform selectivity and kinetics of 4-methylumbelliferone and 1-naphthol glucuronidation, effects of organic solvents, and inhibition by diclofenac and probenecid
-
DOI 10.1124/dmd.32.4.413
-
Uchaipichat V, Mackenzie PI, Guo XH, Gardner-Stephen D, Galetin A, Houston JB, and Miners JO (2004) Human udp-glucuronosyltransferases: isoform selectivity and kinetics of 4-methylumbelliferone and 1-naphthol glucuronidation, effects of organic solvents, and inhibition by diclofenac and probenecid. Drug Metab Dispos 32:413-423. (Pubitemid 38420275)
-
(2004)
Drug Metabolism and Disposition
, vol.32
, Issue.4
, pp. 413-423
-
-
Uchaipichat, V.1
Mackenzie, P.I.2
Guo, X.-H.3
Gardner-Stephen, D.4
Galetin, A.5
Houston, J.B.6
Miners, J.O.7
|