메뉴 건너뛰기




Volumn 168, Issue 2, 2013, Pages 502-517

Abnormal NMDA receptor function exacerbates experimental autoimmune encephalomyelitis

Author keywords

excitotoxicity; glutamate; inflammation; multiple sclerosis; neurodegeneration

Indexed keywords

6 CYANO 7 NITRO 2,3 QUINOXALINEDIONE; DIZOCILPINE; GLUTAMIC ACID; MOG 3555; MYELIN OLIGODENDROCYTE GLYCOPROTEIN; MYELIN OLIGODENDROCYTE GLYCOPROTEIN 35 55; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; UNCLASSIFIED DRUG; VOLTAGE DEPENDENT ANION CHANNEL; VOLTAGE GATED SODIUM CHANNEL;

EID: 84871575473     PISSN: 00071188     EISSN: 14765381     Source Type: Journal    
DOI: 10.1111/j.1476-5381.2012.02178.x     Document Type: Article
Times cited : (39)

References (93)
  • 1
    • 0026609559 scopus 로고
    • Alternative excitotoxic hypotheses
    • Albin RL, Greenamyre JT, (1992). Alternative excitotoxic hypotheses. Neurology 42: 733-738.
    • (1992) Neurology , vol.42 , pp. 733-738
    • Albin, R.L.1    Greenamyre, J.T.2
  • 2
    • 81355156238 scopus 로고    scopus 로고
    • Guide to Receptors and Channels (GRAC), 5th edition (2011)
    • Alexander SPH, Mathie A, Peters JA, (2011). Guide to Receptors and Channels (GRAC), 5th edition (2011). Br J Pharmacol 164: S1-S324.
    • (2011) Br J Pharmacol , vol.164
    • Alexander, S.P.H.1    Mathie, A.2    Peters, J.A.3
  • 3
    • 1842558602 scopus 로고    scopus 로고
    • Molecular mechanisms of glutamate-dependent neurodegeneration in ischemia and traumatic brain injury
    • Arundine M, Tymianski M, (2004). Molecular mechanisms of glutamate-dependent neurodegeneration in ischemia and traumatic brain injury. Cell Mol Life Sci 61: 657-668.
    • (2004) Cell Mol Life Sci , vol.61 , pp. 657-668
    • Arundine, M.1    Tymianski, M.2
  • 4
  • 5
    • 0036141452 scopus 로고    scopus 로고
    • T2 hypointensity in the deep gray matter of patients with multiple sclerosis: A quantitative magnetic resonance imaging study
    • Bakshi R, Benedict RH, Bermel RA, Caruthers SD, Puli SR, Tjoa CW, et al,. (2002). T2 hypointensity in the deep gray matter of patients with multiple sclerosis: a quantitative magnetic resonance imaging study. Arch Neurol 59: 62-68.
    • (2002) Arch Neurol , vol.59 , pp. 62-68
    • Bakshi, R.1    Benedict, R.H.2    Bermel, R.A.3    Caruthers, S.D.4    Puli, S.R.5    Tjoa, C.W.6
  • 7
    • 84856702269 scopus 로고    scopus 로고
    • Basal ganglia, thalamus and neocortical atrophy predicting slowed cognitive processing in multiple sclerosis
    • Batista S, Zivadinov R, Hoogs M, Bergsland N, Heininen-Brown M, Dwyer MG, et al,. (2012). Basal ganglia, thalamus and neocortical atrophy predicting slowed cognitive processing in multiple sclerosis. J Neurol 259: 139-146.
    • (2012) J Neurol , vol.259 , pp. 139-146
    • Batista, S.1    Zivadinov, R.2    Hoogs, M.3    Bergsland, N.4    Heininen-Brown, M.5    Dwyer, M.G.6
  • 8
    • 0030868197 scopus 로고    scopus 로고
    • MK-801 limits neurovascular dysfunction during experimental allergic encephalomyelitis
    • Bolton C, Paul C, (1997). MK-801 limits neurovascular dysfunction during experimental allergic encephalomyelitis. J Pharmacol Exp Ther 282: 397-402.
    • (1997) J Pharmacol Exp Ther , vol.282 , pp. 397-402
    • Bolton, C.1    Paul, C.2
  • 9
    • 33750353468 scopus 로고    scopus 로고
    • NAD(P)H fluorescence transients after synaptic activity in brain slices: Predominant role of mitochondrial function
    • Brennan AM, Connor JA, Shuttleworth CW, (2006). NAD(P)H fluorescence transients after synaptic activity in brain slices: predominant role of mitochondrial function. J Cereb Blood Flow Metab 26: 1389-1406.
    • (2006) J Cereb Blood Flow Metab , vol.26 , pp. 1389-1406
    • Brennan, A.M.1    Connor, J.A.2    Shuttleworth, C.W.3
  • 10
    • 35848954074 scopus 로고    scopus 로고
    • Modulation of the amplitude of NAD(P)H fluorescence transients after synaptic stimulation
    • Brennan AM, Connor JA, Shuttleworth CW, (2007). Modulation of the amplitude of NAD(P)H fluorescence transients after synaptic stimulation. J Neurosci Res 85: 3233-3243.
    • (2007) J Neurosci Res , vol.85 , pp. 3233-3243
    • Brennan, A.M.1    Connor, J.A.2    Shuttleworth, C.W.3
  • 11
    • 78650086750 scopus 로고    scopus 로고
    • KB-R7943, an inhibitor of the reverse Na+ /Ca2+ exchanger, blocks N-methyl-D-aspartate receptor and inhibits mitochondrial complex i
    • Brustovetsky T, Brittain MK, Sheets PL, Cummins TR, Pinelis V, Brustovetsky N, (2011). KB-R7943, an inhibitor of the reverse Na+ /Ca2+ exchanger, blocks N-methyl-D-aspartate receptor and inhibits mitochondrial complex I. Br J Pharmacol 162: 255-270.
    • (2011) Br J Pharmacol , vol.162 , pp. 255-270
    • Brustovetsky, T.1    Brittain, M.K.2    Sheets, P.L.3    Cummins, T.R.4    Pinelis, V.5    Brustovetsky, N.6
  • 12
    • 77957594342 scopus 로고    scopus 로고
    • Basal ganglia and frontal/parietal cortical atrophy is associated with fatigue in relapsing-remitting multiple sclerosis
    • Calabrese M, Rinaldi F, Grossi P, Mattisi I, Bernardi V, Favaretto A, et al,. (2010). Basal ganglia and frontal/parietal cortical atrophy is associated with fatigue in relapsing-remitting multiple sclerosis. Mult Scler 16: 1220-1228.
    • (2010) Mult Scler , vol.16 , pp. 1220-1228
    • Calabrese, M.1    Rinaldi, F.2    Grossi, P.3    Mattisi, I.4    Bernardi, V.5    Favaretto, A.6
  • 14
    • 63849213783 scopus 로고    scopus 로고
    • Inflammation triggers synaptic alteration and degeneration in experimental autoimmune encephalomyelitis
    • Centonze D, Muzio L, Rossi S, Cavasinni F, De Chiara V, Bergami A, et al,. (2009). Inflammation triggers synaptic alteration and degeneration in experimental autoimmune encephalomyelitis. J Neurosci 29: 3442-3452.
    • (2009) J Neurosci , vol.29 , pp. 3442-3452
    • Centonze, D.1    Muzio, L.2    Rossi, S.3    Cavasinni, F.4    De Chiara, V.5    Bergami, A.6
  • 15
    • 0000613615 scopus 로고
    • Intracellular oxidation-reduction states in vivo
    • Chance B, Cohen P, Jobsis F, Schoener B, (1962). Intracellular oxidation-reduction states in vivo. Science 137: 499-508.
    • (1962) Science , vol.137 , pp. 499-508
    • Chance, B.1    Cohen, P.2    Jobsis, F.3    Schoener, B.4
  • 16
    • 33847157194 scopus 로고    scopus 로고
    • Metabolite findings in tumefactive demyelinating lesions utilizing short echo time proton magnetic resonance spectroscopy
    • Cianfoni A, Niku S, Imbesi SG, (2007). Metabolite findings in tumefactive demyelinating lesions utilizing short echo time proton magnetic resonance spectroscopy. AJNR Am J Neuroradiol 28: 272-277.
    • (2007) AJNR Am J Neuroradiol , vol.28 , pp. 272-277
    • Cianfoni, A.1    Niku, S.2    Imbesi, S.G.3
  • 17
    • 54149084585 scopus 로고    scopus 로고
    • Multiple sclerosis
    • Compston A, Coles A, (2008). Multiple sclerosis. Lancet 372: 1502-1517.
    • (2008) Lancet , vol.372 , pp. 1502-1517
    • Compston, A.1    Coles, A.2
  • 18
    • 0017147001 scopus 로고
    • Relation between oxidative metabolism and slow rhythmic potentials in mammalian intestinal muscle
    • Connor JA, Kreulen DL, Prosser CL, (1976). Relation between oxidative metabolism and slow rhythmic potentials in mammalian intestinal muscle. Proc Natl Acad Sci U S A 73: 4239-4243.
    • (1976) Proc Natl Acad Sci U S A , vol.73 , pp. 4239-4243
    • Connor, J.A.1    Kreulen, D.L.2    Prosser, C.L.3
  • 19
    • 0141566748 scopus 로고    scopus 로고
    • Temporal course of upregulation of Na(v)1.8 in Purkinje neurons parallels the progression of clinical deficit in experimental allergic encephalomyelitis
    • Craner MJ, Kataoka Y, Lo AC, Black JA, Baker D, Waxman SG, (2003). Temporal course of upregulation of Na(v)1.8 in Purkinje neurons parallels the progression of clinical deficit in experimental allergic encephalomyelitis. J Neuropathol Exp Neurol 62: 968-975.
    • (2003) J Neuropathol Exp Neurol , vol.62 , pp. 968-975
    • Craner, M.J.1    Kataoka, Y.2    Lo, A.C.3    Black, J.A.4    Baker, D.5    Waxman, S.G.6
  • 20
    • 0742305831 scopus 로고    scopus 로고
    • Co-localization of sodium channel Nav1.6 and the sodium-calcium exchanger at sites of axonal injury in the spinal cord in EAE
    • Craner MJ, Hains BC, Lo AC, Black JA, Waxman SG, (2004a). Co-localization of sodium channel Nav1.6 and the sodium-calcium exchanger at sites of axonal injury in the spinal cord in EAE. Brain 127: 294-303.
    • (2004) Brain , vol.127 , pp. 294-303
    • Craner, M.J.1    Hains, B.C.2    Lo, A.C.3    Black, J.A.4    Waxman, S.G.5
  • 21
    • 2542619146 scopus 로고    scopus 로고
    • Molecular changes in neurons in multiple sclerosis: Altered axonal expression of Nav1.2 and Nav1.6 sodium channels and Na+/Ca2+ exchanger
    • Craner MJ, Newcombe J, Black JA, Hartle C, Cuzner ML, Waxman SG, (2004b). Molecular changes in neurons in multiple sclerosis: altered axonal expression of Nav1.2 and Nav1.6 sodium channels and Na+/Ca2+ exchanger. Proc Natl Acad Sci U S A 101: 8168-8173.
    • (2004) Proc Natl Acad Sci U S A , vol.101 , pp. 8168-8173
    • Craner, M.J.1    Newcombe, J.2    Black, J.A.3    Hartle, C.4    Cuzner, M.L.5    Waxman, S.G.6
  • 22
    • 57049142576 scopus 로고    scopus 로고
    • Time-dependent increases in protease activities for neuronal apoptosis in spinal cords of Lewis rats during development of acute experimental autoimmune encephalomyelitis
    • Das A, Guyton MK, Matzelle DD, Ray SK, Banik NL, (2008). Time-dependent increases in protease activities for neuronal apoptosis in spinal cords of Lewis rats during development of acute experimental autoimmune encephalomyelitis. J Neurosci Res 86: 2992-3001.
    • (2008) J Neurosci Res , vol.86 , pp. 2992-3001
    • Das, A.1    Guyton, M.K.2    Matzelle, D.D.3    Ray, S.K.4    Banik, N.L.5
  • 23
    • 85057918783 scopus 로고    scopus 로고
    • Presynaptic NMDA Receptors
    • Van Dongen A.M. (ed.). CRC Press: Boca Raton, FL
    • Duguid IC, Smart TG, (2009). Presynaptic NMDA Receptors. In:, Van Dongen AM, (ed.). Biology of the NMDA Receptor. CRC Press: Boca Raton, FL, pp. 313-328.
    • (2009) Biology of the NMDA Receptor , pp. 313-328
    • Duguid, I.C.1    Smart, T.G.2
  • 24
    • 33746196730 scopus 로고    scopus 로고
    • A physiological mechanism to regulate d-aspartic acid and NMDA levels in mammals revealed by d-aspartate oxidase deficient mice
    • Errico F, Pirro MT, Affuso A, Spinelli P, De Felice M, D'Aniello A, et al,. (2006). A physiological mechanism to regulate d-aspartic acid and NMDA levels in mammals revealed by d-aspartate oxidase deficient mice. Gene 374: 50-57.
    • (2006) Gene , vol.374 , pp. 50-57
    • Errico, F.1    Pirro, M.T.2    Affuso, A.3    Spinelli, P.4    De Felice, M.5    D'Aniello, A.6
  • 25
    • 55249126223 scopus 로고    scopus 로고
    • D-aspartate prevents corticostriatal long-term depression and attenuates schizophrenia-like symptoms induced by amphetamine and MK-801
    • Errico F, Rossi S, Napolitano F, Catuogno V, Topo E, Fisone G, et al,. (2008). d-aspartate prevents corticostriatal long-term depression and attenuates schizophrenia-like symptoms induced by amphetamine and MK-801. J Neurosci 28: 10404-10414.
    • (2008) J Neurosci , vol.28 , pp. 10404-10414
    • Errico, F.1    Rossi, S.2    Napolitano, F.3    Catuogno, V.4    Topo, E.5    Fisone, G.6
  • 26
    • 58149460658 scopus 로고    scopus 로고
    • Postsynaptic mechanisms of excitotoxicity: Involvement of postsynaptic density proteins, radicals, and oxidant molecules
    • Forder JP, Tymianski M, (2009). Postsynaptic mechanisms of excitotoxicity: involvement of postsynaptic density proteins, radicals, and oxidant molecules. Neuroscience 158: 293-300.
    • (2009) Neuroscience , vol.158 , pp. 293-300
    • Forder, J.P.1    Tymianski, M.2
  • 27
    • 77952403219 scopus 로고    scopus 로고
    • Estradiol inhibits ongoing autoimmune neuroinflammation and NFkappaB-dependent CCL2 expression in reactive astrocytes
    • Giraud SN, Caron CM, Pham-Dinh D, Kitabgi P, Nicot AB, (2010). Estradiol inhibits ongoing autoimmune neuroinflammation and NFkappaB-dependent CCL2 expression in reactive astrocytes. Proc Natl Acad Sci U S A 107: 8416-8421.
    • (2010) Proc Natl Acad Sci U S A , vol.107 , pp. 8416-8421
    • Giraud, S.N.1    Caron, C.M.2    Pham-Dinh, D.3    Kitabgi, P.4    Nicot, A.B.5
  • 28
    • 70449441220 scopus 로고    scopus 로고
    • BMP signaling mediates effects of exercise on hippocampal neurogenesis and cognition in mice
    • Gobeske KT, Das S, Bonaguidi MA, Weiss C, Radulovic J, Disterhoft JF, et al,. (2009). BMP signaling mediates effects of exercise on hippocampal neurogenesis and cognition in mice. Plos ONE 4: e7506.
    • (2009) Plos ONE , vol.4
    • Gobeske, K.T.1    Das, S.2    Bonaguidi, M.A.3    Weiss, C.4    Radulovic, J.5    Disterhoft, J.F.6
  • 29
    • 53049093018 scopus 로고    scopus 로고
    • Neurodegeneration in multiple sclerosis: The role of oxidative stress and excitotoxicity
    • Gonsette RE, (2008). Neurodegeneration in multiple sclerosis: the role of oxidative stress and excitotoxicity. J Neurol Sci 274: 48-53.
    • (2008) J Neurol Sci , vol.274 , pp. 48-53
    • Gonsette, R.E.1
  • 30
    • 80051769464 scopus 로고    scopus 로고
    • Macroglial plasticity and the origins of reactive astroglia in experimental autoimmune encephalomyelitis
    • Guo F, Maeda Y, Ma J, Delgado M, Sohn J, Miers L, et al,. (2011). Macroglial plasticity and the origins of reactive astroglia in experimental autoimmune encephalomyelitis. J Neurosci 31: 11914-11928.
    • (2011) J Neurosci , vol.31 , pp. 11914-11928
    • Guo, F.1    Maeda, Y.2    Ma, J.3    Delgado, M.4    Sohn, J.5    Miers, L.6
  • 31
    • 84855702764 scopus 로고    scopus 로고
    • Disruption of NMDA receptors in oligodendroglial lineage cells does not alter their susceptibility to experimental autoimmune encephalomyelitis or their normal development
    • Guo F, Maeda Y, Ko EM, Delgado M, Horiuchi M, Soulika A, et al,. (2012). Disruption of NMDA receptors in oligodendroglial lineage cells does not alter their susceptibility to experimental autoimmune encephalomyelitis or their normal development. J Neurosci 32: 639-645.
    • (2012) J Neurosci , vol.32 , pp. 639-645
    • Guo, F.1    Maeda, Y.2    Ko, E.M.3    Delgado, M.4    Horiuchi, M.5    Soulika, A.6
  • 33
    • 0031148953 scopus 로고    scopus 로고
    • Glutamate metabolism is down-regulated in astrocytes during experimental allergic encephalomyelitis
    • Hardin-Pouzet H, Krakowski M, Bourbonniere L, Didier-Bazes M, Tran E, Owens T, (1997). Glutamate metabolism is down-regulated in astrocytes during experimental allergic encephalomyelitis. Glia 20: 79-85.
    • (1997) Glia , vol.20 , pp. 79-85
    • Hardin-Pouzet, H.1    Krakowski, M.2    Bourbonniere, L.3    Didier-Bazes, M.4    Tran, E.5    Owens, T.6
  • 34
    • 80053621692 scopus 로고    scopus 로고
    • Impact of extended-release dalfampridine on walking ability in patients with multiple sclerosis
    • Hayes KC, (2011). Impact of extended-release dalfampridine on walking ability in patients with multiple sclerosis. Neuropsychiatr Dis Treat 7: 229-239.
    • (2011) Neuropsychiatr Dis Treat , vol.7 , pp. 229-239
    • Hayes, K.C.1
  • 36
    • 34447640526 scopus 로고    scopus 로고
    • The involvement of mitochondria in the pathogenesis of multiple sclerosis
    • Kalman B, Laitinen K, Komoly S, (2007). The involvement of mitochondria in the pathogenesis of multiple sclerosis. J Neuroimmunol 188: 1-12.
    • (2007) J Neuroimmunol , vol.188 , pp. 1-12
    • Kalman, B.1    Laitinen, K.2    Komoly, S.3
  • 37
    • 79960152288 scopus 로고    scopus 로고
    • A possible pivotal role of mitochondrial free calcium in neurotoxicity mediated by N-methyl-d-aspartate receptors in cultured rat hippocampal neurons
    • Kambe Y, Nakamichi N, Takarada T, Fukumori R, Nakazato R, Hinoi E, et al,. (2011). A possible pivotal role of mitochondrial free calcium in neurotoxicity mediated by N-methyl-d-aspartate receptors in cultured rat hippocampal neurons. Neurochem Int 59: 10-20.
    • (2011) Neurochem Int , vol.59 , pp. 10-20
    • Kambe, Y.1    Nakamichi, N.2    Takarada, T.3    Fukumori, R.4    Nakazato, R.5    Hinoi, E.6
  • 38
    • 20444424174 scopus 로고    scopus 로고
    • Glutamate inhibition in MS: The neuroprotective properties of riluzole
    • Killestein J, Kalkers NF, Polman CH, (2005). Glutamate inhibition in MS: the neuroprotective properties of riluzole. J Neurol Sci 233: 113-115.
    • (2005) J Neurol Sci , vol.233 , pp. 113-115
    • Killestein, J.1    Kalkers, N.F.2    Polman, C.H.3
  • 39
    • 84859401434 scopus 로고    scopus 로고
    • Quantitative high-field imaging of sub-cortical gray matter in multiple sclerosis
    • Lebel RM, Eissa A, Seres P, Blevins G, Wilman AH, (2012). Quantitative high-field imaging of sub-cortical gray matter in multiple sclerosis. Mult Scler 18: 433-441.
    • (2012) Mult Scler , vol.18 , pp. 433-441
    • Lebel, R.M.1    Eissa, A.2    Seres, P.3    Blevins, G.4    Wilman, A.H.5
  • 40
    • 84859006923 scopus 로고    scopus 로고
    • The N-methyl-d-aspartic acid receptor antagonist memantine ameliorates and delays the development of arthritis by enhancing regulatory T cells
    • Lindblad SS, Mydel P, Hellvard A, Jonsson IM, Bokarewa MI, (2012). The N-methyl-d-aspartic acid receptor antagonist memantine ameliorates and delays the development of arthritis by enhancing regulatory T cells. Neurosignals 20: 61-71.
    • (2012) Neurosignals , vol.20 , pp. 61-71
    • Lindblad, S.S.1    Mydel, P.2    Hellvard, A.3    Jonsson, I.M.4    Bokarewa, M.I.5
  • 41
    • 79951625758 scopus 로고    scopus 로고
    • Reorganization in cognitive networks with progression of multiple sclerosis: Insights from fMRI
    • Loitfelder M, Fazekas F, Petrovic K, Fuchs S, Ropele S, Wallner-Blazek M, et al,. (2011). Reorganization in cognitive networks with progression of multiple sclerosis: insights from fMRI. Neurology 76: 526-533.
    • (2011) Neurology , vol.76 , pp. 526-533
    • Loitfelder, M.1    Fazekas, F.2    Petrovic, K.3    Fuchs, S.4    Ropele, S.5    Wallner-Blazek, M.6
  • 42
    • 76049123627 scopus 로고    scopus 로고
    • Dynamic NAD(P)H post-synaptic autofluorescence signals for the assessment of mitochondrial function in a neurodegenerative disease: Monitoring the primary motor cortex of G93A mice, an amyotrophic lateral sclerosis model
    • Loizzo S, Pieri M, Ferri A, Carri MT, Zona C, Fortuna A, et al,. (2010). Dynamic NAD(P)H post-synaptic autofluorescence signals for the assessment of mitochondrial function in a neurodegenerative disease: monitoring the primary motor cortex of G93A mice, an amyotrophic lateral sclerosis model. Mitochondrion 10: 108-114.
    • (2010) Mitochondrion , vol.10 , pp. 108-114
    • Loizzo, S.1    Pieri, M.2    Ferri, A.3    Carri, M.T.4    Zona, C.5    Fortuna, A.6
  • 43
    • 0033004856 scopus 로고    scopus 로고
    • Presynaptic ionotropic receptors and the control of transmitter release
    • MacDermott AB, Role LW, Siegelbaum SA, (1999). Presynaptic ionotropic receptors and the control of transmitter release. Annu Rev Neurosci 22: 443-485.
    • (1999) Annu Rev Neurosci , vol.22 , pp. 443-485
    • MacDermott, A.B.1    Role, L.W.2    Siegelbaum, S.A.3
  • 44
    • 46849122006 scopus 로고    scopus 로고
    • Mitochondrial defects in acute multiple sclerosis lesions
    • Mahad D, Ziabreva I, Lassmann H, Turnbull D, (2008). Mitochondrial defects in acute multiple sclerosis lesions. Brain 131: 1722-1735.
    • (2008) Brain , vol.131 , pp. 1722-1735
    • Mahad, D.1    Ziabreva, I.2    Lassmann, H.3    Turnbull, D.4
  • 45
    • 0027368451 scopus 로고
    • Modulation of synaptic transmission and long-term potentiation: Effects on paired pulse facilitation and EPSC variance in the CA1 region of the hippocampus
    • Manabe T, Wyllie DJ, Perkel DJ, Nicoll RA, (1993). Modulation of synaptic transmission and long-term potentiation: effects on paired pulse facilitation and EPSC variance in the CA1 region of the hippocampus. J Neurophysiol 70: 1451-1459.
    • (1993) J Neurophysiol , vol.70 , pp. 1451-1459
    • Manabe, T.1    Wyllie, D.J.2    Perkel, D.J.3    Nicoll, R.A.4
  • 46
    • 77549083017 scopus 로고    scopus 로고
    • Calcium dyshomeostasis in white matter pathology
    • Matute C, (2010). Calcium dyshomeostasis in white matter pathology. Cell Calcium 47: 150-157.
    • (2010) Cell Calcium , vol.47 , pp. 150-157
    • Matute, C.1
  • 48
    • 0023799539 scopus 로고
    • Fiber optic surface fluorometry/reflectometry and 31-p-NMR for monitoring the intracellular energy state in vivo
    • Mayevsky A, Nioka S, Chance B, (1988). Fiber optic surface fluorometry/reflectometry and 31-p-NMR for monitoring the intracellular energy state in vivo. Adv Exp Med Biol 222: 365-374.
    • (1988) Adv Exp Med Biol , vol.222 , pp. 365-374
    • Mayevsky, A.1    Nioka, S.2    Chance, B.3
  • 49
    • 77954331629 scopus 로고    scopus 로고
    • Guidelines for reportingexperiments involving animals: The ARRIVE guidelines
    • (2010)
    • McGrath J, Drummond G, McLachlan E, Kilkenny C, Wainwright C, (2010). Guidelines for reportingexperiments involving animals: the ARRIVE guidelines. Br J Pharmacol 160: 1573-1576.
    • Br J Pharmacol , vol.160 , pp. 1573-1576
    • McGrath, J.1    Drummond, G.2    McLachlan, E.3    Kilkenny, C.4    Wainwright, C.5
  • 50
    • 27844496574 scopus 로고    scopus 로고
    • Human T lymphocytes express N-methyl-D-aspartate receptors functionally active in controlling T cell activation
    • Miglio G, Varsaldi F, Lombardi G, (2005). Human T lymphocytes express N-methyl-D-aspartate receptors functionally active in controlling T cell activation. Biochem Biophys Res Commun 338: 1875-1883.
    • (2005) Biochem Biophys Res Commun , vol.338 , pp. 1875-1883
    • Miglio, G.1    Varsaldi, F.2    Lombardi, G.3
  • 51
    • 0344688265 scopus 로고    scopus 로고
    • Activity-dependent mRNA splicing controls ER export and synaptic delivery of NMDA receptors
    • Mu Y, Otsuka T, Horton AC, Scott DB, Ehlers MD, (2003). Activity-dependent mRNA splicing controls ER export and synaptic delivery of NMDA receptors. Neuron 40: 581-594.
    • (2003) Neuron , vol.40 , pp. 581-594
    • Mu, Y.1    Otsuka, T.2    Horton, A.C.3    Scott, D.B.4    Ehlers, M.D.5
  • 52
    • 79960207611 scopus 로고    scopus 로고
    • Transient receptor potential vanilloid 1 channels modulate the synaptic effects of TNF-α and of IL-1β in experimental autoimmune encephalomyelitis
    • Musumeci G, Grasselli G, Rossi S, De Chiara V, Musella A, Motta C, et al,. (2011). Transient receptor potential vanilloid 1 channels modulate the synaptic effects of TNF-α and of IL-1β in experimental autoimmune encephalomyelitis. Neurobiol Dis 43: 669-677.
    • (2011) Neurobiol Dis , vol.43 , pp. 669-677
    • Musumeci, G.1    Grasselli, G.2    Rossi, S.3    De Chiara, V.4    Musella, A.5    Motta, C.6
  • 54
    • 0033047334 scopus 로고    scopus 로고
    • Expression mechanisms underlying NMDA receptor-dependent long-term potentiation
    • Nicoll RA, Malenka RC, (1999). Expression mechanisms underlying NMDA receptor-dependent long-term potentiation. Ann N Y Acad Sci 868: 515-525.
    • (1999) Ann N y Acad Sci , vol.868 , pp. 515-525
    • Nicoll, R.A.1    Malenka, R.C.2
  • 55
    • 0036228051 scopus 로고    scopus 로고
    • Altered expression of glutamate transporters in experimental autoimmune encephalomyelitis
    • Ohgoh M, Hanada T, Smith T, Hashimoto T, Ueno M, Yamanishi Y, et al,. (2002). Altered expression of glutamate transporters in experimental autoimmune encephalomyelitis. J Neuroimmunol 125: 170-178.
    • (2002) J Neuroimmunol , vol.125 , pp. 170-178
    • Ohgoh, M.1    Hanada, T.2    Smith, T.3    Hashimoto, T.4    Ueno, M.5    Yamanishi, Y.6
  • 56
    • 77952106356 scopus 로고    scopus 로고
    • A diminished response to formalin stimulation reveals a role for the glutamate transporters in the altered pain sensitivity of mice with experimental autoimmune encephalomyelitis (EAE)
    • Olechowski CJ, Parmar A, Miller B, Stephan J, Tenorio G, Tran K, et al,. (2010). A diminished response to formalin stimulation reveals a role for the glutamate transporters in the altered pain sensitivity of mice with experimental autoimmune encephalomyelitis (EAE). Pain 149: 565-572.
    • (2010) Pain , vol.149 , pp. 565-572
    • Olechowski, C.J.1    Parmar, A.2    Miller, B.3    Stephan, J.4    Tenorio, G.5    Tran, K.6
  • 57
    • 0014668762 scopus 로고
    • Brain lesions, obesity, and other disturbances in mice treated with monosodium glutamate
    • Olney JW, (1969). Brain lesions, obesity, and other disturbances in mice treated with monosodium glutamate. Science 164: 719-721.
    • (1969) Science , vol.164 , pp. 719-721
    • Olney, J.W.1
  • 59
    • 33847203207 scopus 로고    scopus 로고
    • Astrocytes target presynaptic NMDA receptors to give synapses a boost
    • Parri R, Crunelli V, (2007). Astrocytes target presynaptic NMDA receptors to give synapses a boost. Nat Neurosci 10: 271-273.
    • (2007) Nat Neurosci , vol.10 , pp. 271-273
    • Parri, R.1    Crunelli, V.2
  • 60
    • 0036085267 scopus 로고    scopus 로고
    • Modulation of blood-brain barrier dysfunction and neurological deficits during acute experimental allergic encephalomyelitis by the N-methyl-D-aspartate receptor antagonist memantine
    • Paul C, Bolton C, (2002). Modulation of blood-brain barrier dysfunction and neurological deficits during acute experimental allergic encephalomyelitis by the N-methyl-D-aspartate receptor antagonist memantine. J Pharmacol Exp Ther 302: 50-57.
    • (2002) J Pharmacol Exp Ther , vol.302 , pp. 50-57
    • Paul, C.1    Bolton, C.2
  • 61
    • 0033958462 scopus 로고    scopus 로고
    • Glutamate excitotoxicity in a model of multiple sclerosis
    • Pitt D, Werner P, Raine CS, (2000). Glutamate excitotoxicity in a model of multiple sclerosis. Nat Med 6: 67-70.
    • (2000) Nat Med , vol.6 , pp. 67-70
    • Pitt, D.1    Werner, P.2    Raine, C.S.3
  • 62
    • 0345327739 scopus 로고    scopus 로고
    • Glutamate uptake by oligodendrocytes: Implications for excitotoxicity in multiple sclerosis
    • Pitt D, Nagelmeier IE, Wilson HC, Raine CS, (2003). Glutamate uptake by oligodendrocytes: implications for excitotoxicity in multiple sclerosis. Neurology 61: 1113-1120.
    • (2003) Neurology , vol.61 , pp. 1113-1120
    • Pitt, D.1    Nagelmeier, I.E.2    Wilson, H.C.3    Raine, C.S.4
  • 63
    • 0023100903 scopus 로고
    • Effectiveness of amantadine in reducing relapses in multiple sclerosis
    • Plaut GS, (1987). Effectiveness of amantadine in reducing relapses in multiple sclerosis. J R Soc Med 80: 91-93.
    • (1987) J R Soc Med , vol.80 , pp. 91-93
    • Plaut, G.S.1
  • 64
    • 78751501874 scopus 로고    scopus 로고
    • Genetically induced adult oligodendrocyte cell death is associated with poor myelin clearance, reduced remyelination, and axonal damage
    • Pohl HB, Porcheri C, Mueggler T, Bachmann LC, Martino G, Riethmacher D, et al,. (2011). Genetically induced adult oligodendrocyte cell death is associated with poor myelin clearance, reduced remyelination, and axonal damage. J Neurosci 31: 1069-1080.
    • (2011) J Neurosci , vol.31 , pp. 1069-1080
    • Pohl, H.B.1    Porcheri, C.2    Mueggler, T.3    Bachmann, L.C.4    Martino, G.5    Riethmacher, D.6
  • 65
    • 33846025116 scopus 로고    scopus 로고
    • Mitochondrial protein nitration primes neurodegeneration in experimental autoimmune encephalomyelitis
    • Qi X, Lewin AS, Sun L, Hauswirth WW, Guy J, (2006). Mitochondrial protein nitration primes neurodegeneration in experimental autoimmune encephalomyelitis. J Biol Chem 281: 31950-31962.
    • (2006) J Biol Chem , vol.281 , pp. 31950-31962
    • Qi, X.1    Lewin, A.S.2    Sun, L.3    Hauswirth, W.W.4    Guy, J.5
  • 66
    • 77949710746 scopus 로고    scopus 로고
    • The NR1 subunit of NMDA receptor regulates monocyte transmigration through the brain endothelial cell barrier
    • Reijerkerk A, Kooij G, van der Pol SM, Leyen T, Lakeman K, Hof B, et al,. (2010). The NR1 subunit of NMDA receptor regulates monocyte transmigration through the brain endothelial cell barrier. J Neurochem 113: 447-453.
    • (2010) J Neurochem , vol.113 , pp. 447-453
    • Reijerkerk, A.1    Kooij, G.2    Van Der Pol, S.M.3    Leyen, T.4    Lakeman, K.5    Hof, B.6
  • 67
    • 77954403183 scopus 로고    scopus 로고
    • Glutamate-induced alterations in Ca2+ signaling are modulated by mitochondrial Ca2+ handling capacity in brain slices of R6/1 transgenic mice
    • Rosenstock TR, Bertoncini CR, Teles AV, Hirata H, Fernandes MJ, Smaili SS, (2010). Glutamate-induced alterations in Ca2+ signaling are modulated by mitochondrial Ca2+ handling capacity in brain slices of R6/1 transgenic mice. Eur J Neurosci 32: 60-70.
    • (2010) Eur J Neurosci , vol.32 , pp. 60-70
    • Rosenstock, T.R.1    Bertoncini, C.R.2    Teles, A.V.3    Hirata, H.4    Fernandes, M.J.5    Smaili, S.S.6
  • 68
    • 77957232734 scopus 로고    scopus 로고
    • Abnormal activity of the Na/Ca exchanger enhances glutamate transmission in experimental autoimmune encephalomyelitis
    • Rossi S, De Chiara V, Furlan R, Musella A, Cavasinni F, Muzio L, et al,. (2010). Abnormal activity of the Na/Ca exchanger enhances glutamate transmission in experimental autoimmune encephalomyelitis. Brain Behav Immun 24: 1379-1385.
    • (2010) Brain Behav Immun , vol.24 , pp. 1379-1385
    • Rossi, S.1    De Chiara, V.2    Furlan, R.3    Musella, A.4    Cavasinni, F.5    Muzio, L.6
  • 70
    • 84856174835 scopus 로고    scopus 로고
    • Interleukin-1β causes synaptic hyperexcitability in multiple sclerosis
    • Rossi S, Furlan R, De Chiara V, Motta C, Studer V, Mori F, et al,. (2012). Interleukin-1β causes synaptic hyperexcitability in multiple sclerosis. Ann Neurol 71: 76-83.
    • (2012) Ann Neurol , vol.71 , pp. 76-83
    • Rossi, S.1    Furlan, R.2    De Chiara, V.3    Motta, C.4    Studer, V.5    Mori, F.6
  • 71
    • 4444262693 scopus 로고    scopus 로고
    • Abnormal Purkinje cell activity in vivo in experimental allergic encephalomyelitis
    • Saab CY, Craner MJ, Kataoka Y, Waxman SG, (2004). Abnormal Purkinje cell activity in vivo in experimental allergic encephalomyelitis. Exp Brain Res 158: 1-8.
    • (2004) Exp Brain Res , vol.158 , pp. 1-8
    • Saab, C.Y.1    Craner, M.J.2    Kataoka, Y.3    Waxman, S.G.4
  • 72
    • 79955693720 scopus 로고    scopus 로고
    • Increased spontaneous apoptosis of rat primary neurospheres in vitro after experimental autoimmune encephalomyelitis
    • Sajad M, Zargan J, Sharma J, Chawla R, Arora R, Umar S, et al,. (2011). Increased spontaneous apoptosis of rat primary neurospheres in vitro after experimental autoimmune encephalomyelitis. Neurochem Res 36: 1017-1026.
    • (2011) Neurochem Res , vol.36 , pp. 1017-1026
    • Sajad, M.1    Zargan, J.2    Sharma, J.3    Chawla, R.4    Arora, R.5    Umar, S.6
  • 73
    • 0043025561 scopus 로고    scopus 로고
    • Excitatory amino acids and multiple sclerosis: Evidence from cerebrospinal fluid
    • Sarchielli P, Greco L, Floridi A, Gallai V, (2003). Excitatory amino acids and multiple sclerosis: evidence from cerebrospinal fluid. Arch Neurol 60: 1082-1088.
    • (2003) Arch Neurol , vol.60 , pp. 1082-1088
    • Sarchielli, P.1    Greco, L.2    Floridi, A.3    Gallai, V.4
  • 74
    • 0034954538 scopus 로고    scopus 로고
    • Monitoring NAD(P)H autofluorescence to assess mitochondrial metabolic functions in rat hippocampal-entorhinal cortex slices
    • Schuchmann S, Kovacs R, Kann O, Heinemann U, Buchheim K, (2001). Monitoring NAD(P)H autofluorescence to assess mitochondrial metabolic functions in rat hippocampal-entorhinal cortex slices. Brain Res Brain Res Protoc 7: 267-276.
    • (2001) Brain Res Brain Res Protoc , vol.7 , pp. 267-276
    • Schuchmann, S.1    Kovacs, R.2    Kann, O.3    Heinemann, U.4    Buchheim, K.5
  • 75
    • 0038673321 scopus 로고    scopus 로고
    • NAD(P)H fluorescence imaging of postsynaptic neuronal activation in murine hippocampal slices
    • Shuttleworth CW, Brennan AM, Connor JA, (2003). NAD(P)H fluorescence imaging of postsynaptic neuronal activation in murine hippocampal slices. J Neurosci 23: 3196-3208.
    • (2003) J Neurosci , vol.23 , pp. 3196-3208
    • Shuttleworth, C.W.1    Brennan, A.M.2    Connor, J.A.3
  • 76
    • 0033963231 scopus 로고    scopus 로고
    • Autoimmune encephalomyelitis ameliorated by AMPA antagonists
    • Smith T, Groom A, Zhu B, Turski L, (2000). Autoimmune encephalomyelitis ameliorated by AMPA antagonists. Nat Med 6: 62-66.
    • (2000) Nat Med , vol.6 , pp. 62-66
    • Smith, T.1    Groom, A.2    Zhu, B.3    Turski, L.4
  • 77
    • 18744407587 scopus 로고    scopus 로고
    • Evidence of elevated glutamate in multiple sclerosis using magnetic resonance spectroscopy at 3 T
    • Srinivasan R, Sailasuta N, Hurd R, Nelson S, Pelletier D, (2005). Evidence of elevated glutamate in multiple sclerosis using magnetic resonance spectroscopy at 3 T. Brain 128: 1016-1025.
    • (2005) Brain , vol.128 , pp. 1016-1025
    • Srinivasan, R.1    Sailasuta, N.2    Hurd, R.3    Nelson, S.4    Pelletier, D.5
  • 78
    • 73049090241 scopus 로고    scopus 로고
    • Differential NMDA receptor-dependent calcium loading and mitochondrial dysfunction in CA1 vs. CA3 hippocampal neurons
    • Stanika RI, Winters CA, Pivovarova NB, Andrews SB, (2010). Differential NMDA receptor-dependent calcium loading and mitochondrial dysfunction in CA1 vs. CA3 hippocampal neurons. Neurobiol Dis 37: 403-411.
    • (2010) Neurobiol Dis , vol.37 , pp. 403-411
    • Stanika, R.I.1    Winters, C.A.2    Pivovarova, N.B.3    Andrews, S.B.4
  • 79
    • 0024347556 scopus 로고
    • Modulation of neurotransmitter release by presynaptic autoreceptors
    • Starke K, Gothert M, Kilbinger H, (1989). Modulation of neurotransmitter release by presynaptic autoreceptors. Physiol Rev 69: 864-989.
    • (1989) Physiol Rev , vol.69 , pp. 864-989
    • Starke, K.1    Gothert, M.2    Kilbinger, H.3
  • 80
    • 0031442231 scopus 로고    scopus 로고
    • Cerebrospinal fluid hypoxanthine, xanthine and uric acid levels may reflect glutamate-mediated excitotoxicity in different neurological diseases
    • Stover JF, Lowitzsch K, Kempski OS, (1997). Cerebrospinal fluid hypoxanthine, xanthine and uric acid levels may reflect glutamate-mediated excitotoxicity in different neurological diseases. Neurosci Lett 238: 25-28.
    • (1997) Neurosci Lett , vol.238 , pp. 25-28
    • Stover, J.F.1    Lowitzsch, K.2    Kempski, O.S.3
  • 81
    • 66149150220 scopus 로고    scopus 로고
    • Deep gray matter atrophy in multiple sclerosis: A tensor based morphometry
    • Tao G, Datta S, He R, Nelson F, Wolinsky JS, Narayana PA, (2009). Deep gray matter atrophy in multiple sclerosis: a tensor based morphometry. J Neurol Sci 282: 39-46.
    • (2009) J Neurol Sci , vol.282 , pp. 39-46
    • Tao, G.1    Datta, S.2    He, R.3    Nelson, F.4    Wolinsky, J.S.5    Narayana, P.A.6
  • 82
    • 0034237814 scopus 로고    scopus 로고
    • Facilitation, augmentation and potentiation at central synapses
    • Thomson AM, (2000). Facilitation, augmentation and potentiation at central synapses. Trends Neurosci 23: 305-312.
    • (2000) Trends Neurosci , vol.23 , pp. 305-312
    • Thomson, A.M.1
  • 84
    • 34548297818 scopus 로고    scopus 로고
    • Altered glutamate reuptake in relapsing-remitting and secondary progressive multiple sclerosis cortex: Correlation with microglia infiltration, demyelination, and neuronal and synaptic damage
    • Vercellino M, Merola A, Piacentino C, Votta B, Capello E, Mancardi GL, et al,. (2007). Altered glutamate reuptake in relapsing-remitting and secondary progressive multiple sclerosis cortex: correlation with microglia infiltration, demyelination, and neuronal and synaptic damage. J Neuropathol Exp Neurol 66: 732-739.
    • (2007) J Neuropathol Exp Neurol , vol.66 , pp. 732-739
    • Vercellino, M.1    Merola, A.2    Piacentino, C.3    Votta, B.4    Capello, E.5    Mancardi, G.L.6
  • 85
    • 0030008498 scopus 로고    scopus 로고
    • Memantine abrogates neurological deficits, but not CNS inflammation, in Lewis rat experimental autoimmune encephalomyelitis
    • Wallström E, Diener P, Ljungdahl A, Khademi M, Nilsson CG, Olsson T, (1996). Memantine abrogates neurological deficits, but not CNS inflammation, in Lewis rat experimental autoimmune encephalomyelitis. J Neurol Sci 137: 89-96.
    • (1996) J Neurol Sci , vol.137 , pp. 89-96
    • Wallström, E.1    Diener, P.2    Ljungdahl, A.3    Khademi, M.4    Nilsson, C.G.5    Olsson, T.6
  • 86
    • 12344264565 scopus 로고    scopus 로고
    • Cerebellar dysfunction in multiple sclerosis: Evidence for an acquired channelopathy
    • Waxman SG, (2005). Cerebellar dysfunction in multiple sclerosis: evidence for an acquired channelopathy. Prog Brain Res 148: 353-365.
    • (2005) Prog Brain Res , vol.148 , pp. 353-365
    • Waxman, S.G.1
  • 87
    • 0034911054 scopus 로고    scopus 로고
    • Multiple sclerosis: Altered glutamate homeostasis in lesions correlates with oligodendrocyte and axonal damage
    • Werner P, Pitt D, Raine CS, (2001). Multiple sclerosis: altered glutamate homeostasis in lesions correlates with oligodendrocyte and axonal damage. Ann Neurol 2: 169-180.
    • (2001) Ann Neurol , vol.2 , pp. 169-180
    • Werner, P.1    Pitt, D.2    Raine, C.S.3
  • 88
    • 77955385260 scopus 로고    scopus 로고
    • Mitochondrial dysfunction: A potential link between neuroinflammation and neurodegeneration?
    • Witte ME, Geurts JJ, de Vries HE, van der Valk P, van Horssen J, (2010). Mitochondrial dysfunction: a potential link between neuroinflammation and neurodegeneration? Mitochondrion 10: 411-418.
    • (2010) Mitochondrion , vol.10 , pp. 411-418
    • Witte, M.E.1    Geurts, J.J.2    De Vries, H.E.3    Van Der Valk, P.4    Van Horssen, J.5
  • 89
    • 12144279973 scopus 로고    scopus 로고
    • A functional interaction of sodium and calcium in the regulation of NMDA receptor activity by remote NMDA receptors
    • Xin WK, Kwan CL, Zhao XH, Xu J, Ellen RP, McCulloch CA, et al,. (2005). A functional interaction of sodium and calcium in the regulation of NMDA receptor activity by remote NMDA receptors. J Neurosci 25: 139-148.
    • (2005) J Neurosci , vol.25 , pp. 139-148
    • Xin, W.K.1    Kwan, C.L.2    Zhao, X.H.3    Xu, J.4    Ellen, R.P.5    McCulloch, C.A.6
  • 90
    • 32544459068 scopus 로고    scopus 로고
    • Tonic facilitation of glutamate release by presynaptic NR2B-containing NMDA receptors is increased in the entorhinal cortex of chronically epileptic rats
    • Yang J, Woodhall GL, Jones RS, (2006). Tonic facilitation of glutamate release by presynaptic NR2B-containing NMDA receptors is increased in the entorhinal cortex of chronically epileptic rats. J Neurosci 26: 406-410.
    • (2006) J Neurosci , vol.26 , pp. 406-410
    • Yang, J.1    Woodhall, G.L.2    Jones, R.S.3
  • 91
    • 54049087697 scopus 로고    scopus 로고
    • Regulation of NMDA receptor subunit expression and its implications for LTD, LTP, and metaplasticity
    • Yashiro K, Philpot BD, (2008). Regulation of NMDA receptor subunit expression and its implications for LTD, LTP, and metaplasticity. Neuropharmacology 55: 1081-1094.
    • (2008) Neuropharmacology , vol.55 , pp. 1081-1094
    • Yashiro, K.1    Philpot, B.D.2
  • 92
    • 29844453962 scopus 로고    scopus 로고
    • The role of intracellular sodium in the regulation of NMDA-receptor-mediated channel activity and toxicity
    • Yu XM, (2006). The role of intracellular sodium in the regulation of NMDA-receptor-mediated channel activity and toxicity. Mol Neurobiol 33: 63-80.
    • (2006) Mol Neurobiol , vol.33 , pp. 63-80
    • Yu, X.M.1
  • 93
    • 77951792412 scopus 로고    scopus 로고
    • Hippocampal CA1 atrophy and synaptic loss during experimental autoimmune encephalomyelitis, EAE
    • Ziehn MO, Avedisian AA, Tiwari-Woodruff S, Voskuhl RR, (2010). Hippocampal CA1 atrophy and synaptic loss during experimental autoimmune encephalomyelitis, EAE. Lab Invest 90: 774-786.
    • (2010) Lab Invest , vol.90 , pp. 774-786
    • Ziehn, M.O.1    Avedisian, A.A.2    Tiwari-Woodruff, S.3    Voskuhl, R.R.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.