Conserved Acidic Amino Acid Residues in a Second RNA Recognition Motif Regulate Assembly and Function of TDP-43

PLoS ONE

Volumn 7, Issue 12, 2012, Pages

  Shodai, Akemi ^a   Ido, Akemi ^a   Fujiwara, Noriko ^b   Ayaki, Takashi ^c   Morimura, Toshifumi ^a   Oono, Miki ^a,c   Uchida, Tsukasa ^a,c   Takahashi, Ryosuke ^c   Ito, Hidefumi ^c,d   Urushitani, Makoto ^a  

^a SHIGA UNIVERSITY OF MEDICAL SCIENCE   (Japan)

^b HYOGO COLLEGE OF MEDICINE   (Japan)

^c KYOTO UNIVERSITY   (Japan)

^d WAKAYAMA MEDICAL UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ASPARTIC ACID; DIMER; GLUTAMIC ACID; GLYCINE; MONOMER; OLIGOMER; REGULATOR PROTEIN; RRM2 PROTEIN; TAR DNA BINDING PROTEIN; UNCLASSIFIED DRUG;

ADULT; AGED; AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; AMYOTROPHIC LATERAL SCLEROSIS; ARTICLE; BINDING AFFINITY; CELL CULTURE; CLINICAL ARTICLE; CONTROLLED STUDY; CYTOSOL; DNA BINDING; EMBRYO; FIBER; HUMAN; HUMAN CELL; HUMAN TISSUE; PROTEIN ASSEMBLY; PROTEIN CONFORMATION; PROTEIN DNA INTERACTION; PROTEIN DOMAIN; PROTEIN FOLDING; PROTEIN FUNCTION; PROTEIN STABILITY; RNA SPLICING; SPINAL CORD; WILD TYPE;

AGED; AMINO ACID MOTIFS; AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; AMYOTROPHIC LATERAL SCLEROSIS; ANIMALS; ANTIBODIES, MONOCLONAL, MURINE-DERIVED; CONSERVED SEQUENCE; DNA-BINDING PROTEINS; HEK293 CELLS; HUMANS; HYDROGEN BONDING; INCLUSION BODIES; MICE; MICE, INBRED C57BL; MIDDLE AGED; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; NUCLEAR LOCALIZATION SIGNALS; PROTEIN BINDING; PROTEIN FOLDING; PROTEIN MULTIMERIZATION; PROTEIN STRUCTURE, QUATERNARY; PROTEIN STRUCTURE, TERTIARY; PROTEIN TRANSPORT; RNA SPLICING; SOLUBILITY; SPINAL CORD;

EID: 84871565762     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0052776     Document Type: Article

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