Ubiquitin-specific protease 9x deubiquitinates and stabilizes the spinal muscular atrophy protein-survival motor neuron

Journal of Biological Chemistry

Volumn 287, Issue 52, 2012, Pages 43741-43752

  Han, Ke Jun ^a   Foster, Daniel G ^a   Zhang, Nan Yan ^a,c   Kanisha, Kavdia ^b   Dzieciatkowska, Monika ^a   Sclafani, Robert A ^a   Hansen, Kirk C ^a   Peng, Junmin ^b   Liu, Chang Wei ^a  

^a UNIVERSITY OF COLORADO SCHOOL OF MEDICINE   (United States)

^b ST JUDE CHILDREN S RESEARCH HOSPITAL   (United States)

^c MEDICAL COLLEGE OF WISCONSIN   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DEUBIQUITINATING ENZYMES; GENETIC DISORDERS; INFANT MORTALITY; LOW LEVEL; MAMMALIAN CELLS; MOTOR NEURONS; POST-TRANSCRIPTIONAL; PROTEASOMES; PROTEIN LEVEL; SPINAL MUSCULAR ATROPHY; SURVIVAL MOTOR NEURONS;

BRAIN; NEUROMUSCULAR REHABILITATION; NEURONS; TRANSCRIPTION;

PROTEINS;

PROTEASOME; PROTEINASE; SURVIVAL MOTOR NEURON PROTEIN; SURVIVAL MOTOR NEURON PROTEIN 2; SURVIVAL MOTOR NEURON PROTEIN DELTA7; UBIQUITIN; UBIQUITIN SPECIFIC PROTEASE 9X; UNCLASSIFIED DRUG;

ARTICLE; CELL LEVEL; CELL NUCLEUS; COMPLEX FORMATION; CONTROLLED STUDY; DEUBIQUITINATION; GENE SILENCING; HUMAN; HUMAN CELL; IN VITRO STUDY; MAMMAL CELL; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN DEGRADATION; PROTEIN FUNCTION; PROTEIN MODIFICATION; PROTEIN PROTEIN INTERACTION; PROTEIN STABILITY; SMN2 GENE; SPINAL MUSCULAR ATROPHY; UBIQUITINATION;

GENE KNOCKDOWN TECHNIQUES; HEK293 CELLS; HELA CELLS; HUMANS; PROTEIN STABILITY; PROTEOLYSIS; SPINAL MUSCULAR ATROPHIES OF CHILDHOOD; SURVIVAL OF MOTOR NEURON 1 PROTEIN; SURVIVAL OF MOTOR NEURON 2 PROTEIN; UBIQUITIN THIOLESTERASE; UBIQUITINATION;

MAMMALIA;

EID: 84871547640     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M112.372318     Document Type: Article

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