The Drosophila developmental gene fat facets has a human homologue in Xp11.4 which escapes X-inactivation and has related sequences on Yq11.2

Human Molecular Genetics

Volumn 5, Issue 11, 1996, Pages 1695-1701

  Jones, Michael H ^a,b   Furlong, Robert A ^a   Burkin, Heather ^a   Chalmers, I Jennifer ^a   Brown, Graeme M ^a   Khwaja, Omar ^a   Affara, Nabeel A ^a  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^b CHUGAI PHARMACEUTICAL CO LTD   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

PRIMER DNA; UBIQUITIN;

AMINO ACID SEQUENCE; ARTICLE; CELL PROLIFERATION; CHROMOSOME XP; CHROMOSOME YQ; CONTROLLED STUDY; DEVELOPMENTAL GENETICS; DROSOPHILA; EMBRYO; EMBRYO DEVELOPMENT; FEMALE; GENE LOCUS; GENE MAPPING; GENETIC TRANSCRIPTION; GONADAL DYSGENESIS; HUMAN; HUMAN CELL; HYDROLYSIS; LYMPHOBLASTOID CELL LINE; MALE; NONHUMAN; OOCYTE DEVELOPMENT; OPEN READING FRAME; PRIORITY JOURNAL; PROTEIN DOMAIN; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SEQUENCE HOMOLOGY; TESTIS; TURNER SYNDROME; X CHROMOSOME INACTIVATION;

ADULT; AMINO ACID SEQUENCE; ANIMALS; BASE SEQUENCE; CHROMOSOME MAPPING; CONSERVED SEQUENCE; DNA, COMPLEMENTARY; DOSAGE COMPENSATION, GENETIC; DROSOPHILA; ENDOPEPTIDASES; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GENES; GENES, DEVELOPMENTAL; HUMANS; MALE; MOLECULAR SEQUENCE DATA; ORGAN SPECIFICITY; RNA, MESSENGER; SEQUENCE ANALYSIS, DNA; SEQUENCE HOMOLOGY, AMINO ACID; TESTIS; X CHROMOSOME; Y CHROMOSOME;

EID: 0029830360     PISSN: 09646906     EISSN: None     Source Type: Journal    
DOI: 10.1093/hmg/5.11.1695     Document Type: Article

References (26)

1. Adams et al. (1995). Initial assessment of human gene diversity and expression patterns based upon 83 million nucleotides of cDNA sequence. Nature, 377 (supplement), 3-17.
2. Sargent, C.A., Affara, N.A., Bentley, E., Pelmear, A., Bailey, D.M.D., Davey, P., Dow, D., Leversha, M., Aplin, H., Besley, G. and Ferguson-Smith, M.A. (1993). Cloning of the X-Linked glycerol kinase deficiency gene and its identification by sequence comparison to the Bacillus subtilis homologue. Hum. Mol. Genet., 2, 97-106.
3. Sargent, C.A., Young, C., Marsh, S., Ferguson-Smith, M.A. and Affara, N.A. (1994). The glycerol kinase gene family: structure of the Xp gene, and related intronless retroposons. Hum. Mol. Genet., 3, 1317-1324.
4. Affara, N.A., Bentley, E., Pelmear, A., Davey, P., Jones, M.H. (1994). The identification of novel gene sequences of the adult testis. Genomics, 22, 205-210.
5. Fischer-Vize, J.A., Rubin, G.M. and Lehmann, R. (1992). The fat facets gene is required for Drosophila eye and embryo development. Development, 116, 985-1000.
6. Huang, Y., Baker, R.T. and Fischer-Vize, J.A. (1995). Control of cell fate by a deubiquitinating enzyme encoded by the fat facets gene. Science, 270, 1828-1831.
7. Cockwell, A., MacKenzie, M., Youings, S., Jacobs, P. (1991). A cytogenetic and molecular study of a series of 45,X fetuses and their parents. J. Med. Genet., 28, 151-155.
8. Speed, R.M. (1986). Oocyte development in XO foetuses of man and mouse: the possible role of heterologous X chromosome pairing in germ cell survival. Chromosoma, 94, 115-124.
9. Jones, M.H., Khwaja, O., Briggs, H., Walker, E., Lambson, B., Davey, P., Chalmers, I.J., Zhou, C-Y., Walker, E.M., Zheng, Y., Todd, C., Ferguson-Smith, M.A. and Affara, N.A. (1994). A set of ninety-seven overlapping yeast artificial chromosome clones spanning the human Y chromosome euchromatin. Genomics, 24, 266-275.
10. Affara, N.A., Brown, W., Cooke, H., Davey, P., Ellis, N., Marshall Graves, J., Jones, M., Mitchell, M., Rappold, G., Toder, R., Tyler-Smith, C., Yen, P. and Lau, Y-F. C. (1996). Report of the Second International Workshop on Y Chromosome Mapping 1996. Cell Genet. Cytogenet., 73, 33-76.
11. Nelson, D. L., Ballabio, A., Cremers, F. Monaco, A.P. and Schlessinger, D. (1995). Report of the 6th International Workshop on X Chromosome Mapping 1995. Cytogenet. Cell Genet., 71, 307-342.
12. Kozak, C. (1986). Point mutations define a sequence flanking the AUG initiator codon that modulates translation by eukaryotic ribosomes. Cell, 44, 283-292.
13. Tobias J.W. and Varshavsky A. (1991). Cloning and functional analysis of the ubiquitin-specific protease gene UBP1 of Saccharomyces cerevisiae. J. Biol. Chem., 266, 12021-12028.
14. Baker R.T., Tobias J.W. and Varshavsky A. (1992). Ubiquitin-specific proteases of Saccharomyces cerevisiae - cloning of UBP2 and UBP3, and functional-analysis of the UBP gene family. J. Biol. Chem., 267, 23364-23375.
15. Papa F.R. and Hochstrasser M. (1993). The yeast DOA4 gene encodes a deubiquitinating enzyme related to a product of the human tre-2 oncogene. Nature, 366, 313-319.
16. Banfi, S., Borsani, G., Rossi, E., Bernard, L., Guffanti, A., Rubboli, F., Marchitiello, A., Giglio, S., Coluccia, E., Zollo, M., Zuffardi, O. and Ballabio, A. (1996). Identification and mapping of human cDNAs homologous to Drosophila mutant genes through EST database searching. Nature Genet., 13, 167-174.
17. Roepman R., van Duijnhoven G., Rosenberg T., Pinckers A.J.L.G., Bleeker-Wagemakers L.M., Bergen A.A.B., Post J., Beck A., Reinhardt R., Ropers H-H, Cremers F.P.M. and Berger W. (1996). Positional cloning of the gene for X-linked retinitis pigmentosa 3: homology with the guanine-nucleotide-exchange factor RCC1. Hum. Mol. Genet., 5, 1035-1041.
18. Ogata, T. and Matsuo, N. (1995). Turner syndrome and female sex chromosome aberrations: deduction of the principal factors involved in the development of clinical features. Hum. Genet., 95, 607-629.
19. Ferguson-Smith, M.A. (1965). Karyotype-phenotype correlations in gonadal dysgenesis and their bearing on the pathogenesis of malformations. J. Med. Genet., 2, 142-155.
20. Ferguson-Smith, M.A. (1991). Genotype-phenotype correlations in individuals with disorders of sex determination and development including Turner syndrome. Semin. Dev. Biol., 2, 265-276.
21. Zinn, A.R., Page, D.C., Fisher, E.M.C. (1993). Turner syndrome: the case of the missing sex chromosome. Trends Genet., 9, 90-93.
22. Maniatis, T. Fritsch, E.F. and Sambrook, J. (1982). Molecular Cloning: A Laboratory Handbook. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, New York.
23. Nakamura T., Hillova J., Mariage-Samson R., Onno M., Huebner K., Cannizzaro L.A., Boghosian-Sell L., Croce C.M., and Hill M. (1992). A novel transcriptional unit of the tre oncogene widely expressed in human cancer cells. Oncogene, 7, 733-741.
24. Swanson D.A., Freund C.L., PloderL., McInnes R.R. and Valle D. (1996). A ubiquitin C-terminal hydrolase gene on the proximal short arm of the X chromosome: implications for X-linked retinal disorders. Hum. Mol. Genet., 5, 533-538.
25. Gray D.A., Inazawa J., Gupta K., Wong A., Ueda R. and Takahashi. (1995). Elevated expression of Unph, a proto-oncogene at 3p21.3, in human lung tumors. Oncogene, 10, 2179-2183.
26. Gupta K., Copeland N.G., Gilbert D.J., Jenkins N.A. and Gray D.A. (1993). Unp, a mouse gene related to the tre oncogene. Oncogene, 8, 2307-2310.