메뉴 건너뛰기




Volumn 34, Issue 8, 2013, Pages 1995-2004

Three-dimensional cell aggregates composed of HUVECs and cbMSCs for therapeutic neovascularization in a mouse model of hindlimb ischemia

Author keywords

Cell based therapy; Critical limb ischemia; Neovascularization; Thermo responsive hydrogel; Tissue engineering

Indexed keywords

ADHESION MOLECULES; BLOOD PERFUSION; CELL AGGREGATES; CELL FUNCTIONS; CELL-BASED; CELL-BASED THERAPY; CELL-CELL COMMUNICATIONS; CELL-CELL CONTACT; CRITICAL LIMB ISCHEMIA; EXTRACELLULAR MATRICES; HIND LIMBS; HUMAN UMBILICAL VEIN ENDOTHELIAL CELLS; IMMUNOSTAINING; ISCHEMIC LIMBS; MESENCHYMAL STEM CELL; MOUSE MODELS; MYOCARDIN; NEOVASCULARIZATION; REAL-TIME PCR; SMOOTH MUSCLE CELLS; THERAPEUTIC STRATEGY; THERMO-RESPONSIVE; TUBULAR NETWORKS; TUBULAR STRUCTURES; VESSEL FORMATION;

EID: 84871529171     PISSN: 01429612     EISSN: 18785905     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2012.11.045     Document Type: Article
Times cited : (43)

References (42)
  • 1
    • 79954630368 scopus 로고    scopus 로고
    • Protease-resistant stromal cell-derived factor-1 for the treatment of experimental peripheral artery disease
    • Segers V.F., Revin V., Wu W., Qiu H., Yan Z., Lee R.T., et al. Protease-resistant stromal cell-derived factor-1 for the treatment of experimental peripheral artery disease. Circulation 2011, 123:1306-1315.
    • (2011) Circulation , vol.123 , pp. 1306-1315
    • Segers, V.F.1    Revin, V.2    Wu, W.3    Qiu, H.4    Yan, Z.5    Lee, R.T.6
  • 2
    • 73949085704 scopus 로고    scopus 로고
    • Synergistic effect of HIF-1alpha gene therapy and HIF-1-activated bone marrow-derived angiogenic cells in a mouse model of limb ischemia
    • Rey S., Lee K., Wang C.J., Gupta K., Chen S., McMillan A., et al. Synergistic effect of HIF-1alpha gene therapy and HIF-1-activated bone marrow-derived angiogenic cells in a mouse model of limb ischemia. Proc Natl Acad Sci USA 2009, 106:20399-20404.
    • (2009) Proc Natl Acad Sci USA , vol.106 , pp. 20399-20404
    • Rey, S.1    Lee, K.2    Wang, C.J.3    Gupta, K.4    Chen, S.5    McMillan, A.6
  • 3
    • 84866149882 scopus 로고    scopus 로고
    • Transfection of VEGF(165) genes into endothelial progenitor cells and in vivo imaging using quantum dots in an ischemia hind limb model
    • Yang H.N., Park J.S., Woo D.G., Jeon S.Y., Park K.H. Transfection of VEGF(165) genes into endothelial progenitor cells and in vivo imaging using quantum dots in an ischemia hind limb model. Biomaterials 2012, 33:8670-8684.
    • (2012) Biomaterials , vol.33 , pp. 8670-8684
    • Yang, H.N.1    Park, J.S.2    Woo, D.G.3    Jeon, S.Y.4    Park, K.H.5
  • 4
    • 48849116997 scopus 로고    scopus 로고
    • Role of nox2-based NADPH oxidase in bone marrow and progenitor cell function involved in neovascularization induced by hindlimb ischemia
    • Urao N., Inomata H., Razvi M., Kim H.W., Wary K., McKinney R., et al. Role of nox2-based NADPH oxidase in bone marrow and progenitor cell function involved in neovascularization induced by hindlimb ischemia. Circ Res 2008, 103:212-220.
    • (2008) Circ Res , vol.103 , pp. 212-220
    • Urao, N.1    Inomata, H.2    Razvi, M.3    Kim, H.W.4    Wary, K.5    McKinney, R.6
  • 5
    • 34249732615 scopus 로고    scopus 로고
    • In vivo vasculogenic potential of human blood-derived endothelial progenitor cells
    • Melero-Martin J.M., Khan Z.A., Picard A., Wu X., Paruchuri S., Bischoff J. In vivo vasculogenic potential of human blood-derived endothelial progenitor cells. Blood 2007, 109:4761-4768.
    • (2007) Blood , vol.109 , pp. 4761-4768
    • Melero-Martin, J.M.1    Khan, Z.A.2    Picard, A.3    Wu, X.4    Paruchuri, S.5    Bischoff, J.6
  • 7
    • 67649962976 scopus 로고    scopus 로고
    • Paradoxical effects of PDGF-BB overexpression in endothelial cells on engineered blood vessels in vivo
    • Au P., Tam J., Duda D.G., Lin P.C., Munn L.L., Fukumura D., et al. Paradoxical effects of PDGF-BB overexpression in endothelial cells on engineered blood vessels in vivo. Am J Pathol 2009, 175:294-302.
    • (2009) Am J Pathol , vol.175 , pp. 294-302
    • Au, P.1    Tam, J.2    Duda, D.G.3    Lin, P.C.4    Munn, L.L.5    Fukumura, D.6
  • 8
    • 77950671531 scopus 로고    scopus 로고
    • Micropatterned three-dimensional hydrogel system to study human endothelial-mesenchymal stem cell interactions
    • Trkov S., Eng G., Di Liddo R., Parnigotto P.P., Vunjak-Novakovic G. Micropatterned three-dimensional hydrogel system to study human endothelial-mesenchymal stem cell interactions. J Tissue Eng Regen Med 2010, 4:205-215.
    • (2010) J Tissue Eng Regen Med , vol.4 , pp. 205-215
    • Trkov, S.1    Eng, G.2    Di Liddo, R.3    Parnigotto, P.P.4    Vunjak-Novakovic, G.5
  • 10
    • 61949381850 scopus 로고    scopus 로고
    • Building a vessel wall with notch signaling
    • Regan J.N., Majesky M.W. Building a vessel wall with notch signaling. Circ Res 2009, 104:419-421.
    • (2009) Circ Res , vol.104 , pp. 419-421
    • Regan, J.N.1    Majesky, M.W.2
  • 11
    • 44949166671 scopus 로고    scopus 로고
    • Three-dimensional cell culture matrices: state of the art
    • Lee J., Cuddihy M.J., Kotov N.A. Three-dimensional cell culture matrices: state of the art. Tissue Eng Part B Rev 2008, 14:61-86.
    • (2008) Tissue Eng Part B Rev , vol.14 , pp. 61-86
    • Lee, J.1    Cuddihy, M.J.2    Kotov, N.A.3
  • 12
    • 33644683263 scopus 로고    scopus 로고
    • Endothelial extracellular matrix: biosynthesis, remodeling, and functions during vascular morphogenesis and neovessel stabilization
    • Davis G.E., Senger D.R. Endothelial extracellular matrix: biosynthesis, remodeling, and functions during vascular morphogenesis and neovessel stabilization. Circ Res 2005, 97:1093-1107.
    • (2005) Circ Res , vol.97 , pp. 1093-1107
    • Davis, G.E.1    Senger, D.R.2
  • 13
    • 0042358985 scopus 로고    scopus 로고
    • Cell culture: biology's new dimension
    • Abbott A. Cell culture: biology's new dimension. Nature 2003, 424:870-872.
    • (2003) Nature , vol.424 , pp. 870-872
    • Abbott, A.1
  • 14
    • 0000529678 scopus 로고
    • " ECM" : its nature, origin and function in cell aggregation
    • Steinberg M.S. " ECM" : its nature, origin and function in cell aggregation. Exp Cell Res 1963, 30:257-279.
    • (1963) Exp Cell Res , vol.30 , pp. 257-279
    • Steinberg, M.S.1
  • 16
    • 79951580027 scopus 로고    scopus 로고
    • Angiogenesis in ischemic tissue produced by spheroid grafting of human adipose-derived stromal cells
    • Bhang S.H., Cho S.W., La W.G., Lee T.J., Yang H.S., Sun A.Y., et al. Angiogenesis in ischemic tissue produced by spheroid grafting of human adipose-derived stromal cells. Biomaterials 2011, 32:2734-2747.
    • (2011) Biomaterials , vol.32 , pp. 2734-2747
    • Bhang, S.H.1    Cho, S.W.2    La, W.G.3    Lee, T.J.4    Yang, H.S.5    Sun, A.Y.6
  • 17
    • 68549118666 scopus 로고    scopus 로고
    • The use of injectable spherically symmetric cell aggregates self-assembled in a thermo-responsive hydrogel for enhanced cell transplantation
    • Lee W.Y., Chang Y.H., Yeh Y.C., Chen C.H., Lin K.M., Huang C.C., et al. The use of injectable spherically symmetric cell aggregates self-assembled in a thermo-responsive hydrogel for enhanced cell transplantation. Biomaterials 2009, 30:5505-5513.
    • (2009) Biomaterials , vol.30 , pp. 5505-5513
    • Lee, W.Y.1    Chang, Y.H.2    Yeh, Y.C.3    Chen, C.H.4    Lin, K.M.5    Huang, C.C.6
  • 18
    • 79957881448 scopus 로고    scopus 로고
    • Enhancement of cell retention and functional benefits in myocardial infarction using human amniotic-fluid stem-cell bodies enriched with endogenous ECM
    • Lee W.Y., Wei H.J., Lin W.W., Yeh Y.C., Hwang S.M., Wang J.J., et al. Enhancement of cell retention and functional benefits in myocardial infarction using human amniotic-fluid stem-cell bodies enriched with endogenous ECM. Biomaterials 2011, 32:5558-5567.
    • (2011) Biomaterials , vol.32 , pp. 5558-5567
    • Lee, W.Y.1    Wei, H.J.2    Lin, W.W.3    Yeh, Y.C.4    Hwang, S.M.5    Wang, J.J.6
  • 19
    • 80052961157 scopus 로고    scopus 로고
    • Core-shell cell bodies composed of human cbMSCs and HUVECs for functional vasculogenesis
    • Lee W.Y., Tsai H.W., Chiang J.H., Hwang S.M., Chen D.Y., Hsu L.W., et al. Core-shell cell bodies composed of human cbMSCs and HUVECs for functional vasculogenesis. Biomaterials 2011, 32:8446-8455.
    • (2011) Biomaterials , vol.32 , pp. 8446-8455
    • Lee, W.Y.1    Tsai, H.W.2    Chiang, J.H.3    Hwang, S.M.4    Chen, D.Y.5    Hsu, L.W.6
  • 20
    • 77954443496 scopus 로고    scopus 로고
    • Establishment of immortalized mesenchymal stromal cells with red fluorescence protein expression for in vivo transplantation and tracing in the rat model with traumatic brain injury
    • Hung C.J., Yao C.L., Cheng F.C., Wu M.L., Wang T.H., Hwang S.M. Establishment of immortalized mesenchymal stromal cells with red fluorescence protein expression for in vivo transplantation and tracing in the rat model with traumatic brain injury. Cytotherapy 2010, 12:455-465.
    • (2010) Cytotherapy , vol.12 , pp. 455-465
    • Hung, C.J.1    Yao, C.L.2    Cheng, F.C.3    Wu, M.L.4    Wang, T.H.5    Hwang, S.M.6
  • 21
    • 79952164899 scopus 로고    scopus 로고
    • Dentin matrix protein 1 induces membrane expression of VE-cadherin on endothelial cells and inhibits VEGF-induced angiogenesis by blocking VEGFR-2 phosphorylation
    • Pirotte S., Lamour V., Lambert V., Alvarez Gonzalez M.L., Ormenese S., Noel A., et al. Dentin matrix protein 1 induces membrane expression of VE-cadherin on endothelial cells and inhibits VEGF-induced angiogenesis by blocking VEGFR-2 phosphorylation. Blood 2011, 117:2515-2526.
    • (2011) Blood , vol.117 , pp. 2515-2526
    • Pirotte, S.1    Lamour, V.2    Lambert, V.3    Alvarez Gonzalez, M.L.4    Ormenese, S.5    Noel, A.6
  • 23
    • 33847654322 scopus 로고    scopus 로고
    • The effect of the controlled release of basic fibroblast growth factor from ionic gelatin-based hydrogels on angiogenesis in a murine critical limb ischemic model
    • Layman H., Spiga M.G., Brooks T., Pham S., Webster K.A., Andreopoulos F.M. The effect of the controlled release of basic fibroblast growth factor from ionic gelatin-based hydrogels on angiogenesis in a murine critical limb ischemic model. Biomaterials 2007, 28:2646-2654.
    • (2007) Biomaterials , vol.28 , pp. 2646-2654
    • Layman, H.1    Spiga, M.G.2    Brooks, T.3    Pham, S.4    Webster, K.A.5    Andreopoulos, F.M.6
  • 24
    • 3242695063 scopus 로고    scopus 로고
    • Improvement of postnatal neovascularization by human adipose tissue-derived stem cells
    • Miranville A., Heeschen C., Sengenes C., Curat C.A., Busse R., Bouloumie A. Improvement of postnatal neovascularization by human adipose tissue-derived stem cells. Circulation 2004, 110:349-355.
    • (2004) Circulation , vol.110 , pp. 349-355
    • Miranville, A.1    Heeschen, C.2    Sengenes, C.3    Curat, C.A.4    Busse, R.5    Bouloumie, A.6
  • 25
    • 77953344230 scopus 로고    scopus 로고
    • Cellular cardiomyoplasty with human amniotic fluid stem cells: in vitro and in vivo studies
    • Yeh Y.C., Wei H.J., Lee W.Y., Yu C.L., Chang Y., Hsu L.W., et al. Cellular cardiomyoplasty with human amniotic fluid stem cells: in vitro and in vivo studies. Tissue Eng Part A 2010, 16:1925-1936.
    • (2010) Tissue Eng Part A , vol.16 , pp. 1925-1936
    • Yeh, Y.C.1    Wei, H.J.2    Lee, W.Y.3    Yu, C.L.4    Chang, Y.5    Hsu, L.W.6
  • 26
    • 34547931078 scopus 로고    scopus 로고
    • Modeling tissue morphogenesis and cancer in 3D
    • Yamada K.M., Cukierman E. Modeling tissue morphogenesis and cancer in 3D. Cell 2007, 130:601-610.
    • (2007) Cell , vol.130 , pp. 601-610
    • Yamada, K.M.1    Cukierman, E.2
  • 27
    • 34547871326 scopus 로고    scopus 로고
    • Construction and characterization of fragmented mesenchymal-stem-cell sheets for intramuscular injection
    • Chen C.H., Chang Y., Wang C.C., Huang C.H., Huang C.C., Yeh Y.C., et al. Construction and characterization of fragmented mesenchymal-stem-cell sheets for intramuscular injection. Biomaterials 2007, 28:4643-4651.
    • (2007) Biomaterials , vol.28 , pp. 4643-4651
    • Chen, C.H.1    Chang, Y.2    Wang, C.C.3    Huang, C.H.4    Huang, C.C.5    Yeh, Y.C.6
  • 28
    • 34948881293 scopus 로고    scopus 로고
    • Novel method of forming human embryoid bodies in a polystyrene dish surface-coated with a temperature-responsive methylcellulose hydrogel
    • Yang M.J., Chen C.H., Lin P.J., Huang C.H., Chen W., Sung H.W. Novel method of forming human embryoid bodies in a polystyrene dish surface-coated with a temperature-responsive methylcellulose hydrogel. Biomacromolecules 2007, 8:2746-2752.
    • (2007) Biomacromolecules , vol.8 , pp. 2746-2752
    • Yang, M.J.1    Chen, C.H.2    Lin, P.J.3    Huang, C.H.4    Chen, W.5    Sung, H.W.6
  • 29
    • 34547187820 scopus 로고    scopus 로고
    • Mesenchymal stem cells support migration, extracellular matrix invasion, proliferation, and survival of endothelial cells in vitro
    • Potapova I.A., Gaudette G.R., Brink P.R., Robinson R.B., Rosen M.R., Cohen I.S., et al. Mesenchymal stem cells support migration, extracellular matrix invasion, proliferation, and survival of endothelial cells in vitro. Stem Cells 2007, 25:1761-1768.
    • (2007) Stem Cells , vol.25 , pp. 1761-1768
    • Potapova, I.A.1    Gaudette, G.R.2    Brink, P.R.3    Robinson, R.B.4    Rosen, M.R.5    Cohen, I.S.6
  • 30
    • 0025814829 scopus 로고
    • Intracellular mechanisms involved in basement membrane induced blood vessel differentiation in vitro
    • Grant D.S., Lelkes P.I., Fukuda K., Kleinman H.K. Intracellular mechanisms involved in basement membrane induced blood vessel differentiation in vitro. In Vitro Cell Dev Biol 1991, 27A:327-336.
    • (1991) In Vitro Cell Dev Biol , vol.27 A , pp. 327-336
    • Grant, D.S.1    Lelkes, P.I.2    Fukuda, K.3    Kleinman, H.K.4
  • 31
    • 67650169752 scopus 로고    scopus 로고
    • Hydrogels as extracellular matrix mimics for 3D cell culture
    • Tibbitt M.W., Anseth K.S. Hydrogels as extracellular matrix mimics for 3D cell culture. Biotechnol Bioeng 2009, 103:655-663.
    • (2009) Biotechnol Bioeng , vol.103 , pp. 655-663
    • Tibbitt, M.W.1    Anseth, K.S.2
  • 32
    • 34648834682 scopus 로고    scopus 로고
    • The third dimension bridges the gap between cell culture and live tissue
    • Pampaloni F., Reynaud E.G., Stelzer E.H. The third dimension bridges the gap between cell culture and live tissue. Nat Rev Mol Cell Biol 2007, 8:839-845.
    • (2007) Nat Rev Mol Cell Biol , vol.8 , pp. 839-845
    • Pampaloni, F.1    Reynaud, E.G.2    Stelzer, E.H.3
  • 33
    • 78349308470 scopus 로고    scopus 로고
    • Functional neovascularization of biodegradable dextran hydrogels with multiple angiogenic growth factors
    • Sun G., Shen Y.I., Kusuma S., Fox-Talbot K., Steenbergen C.J., Gerecht S. Functional neovascularization of biodegradable dextran hydrogels with multiple angiogenic growth factors. Biomaterials 2011, 32:95-106.
    • (2011) Biomaterials , vol.32 , pp. 95-106
    • Sun, G.1    Shen, Y.I.2    Kusuma, S.3    Fox-Talbot, K.4    Steenbergen, C.J.5    Gerecht, S.6
  • 34
    • 84860516385 scopus 로고    scopus 로고
    • A comparison of human smooth muscle and mesenchymal stem cells as potential cell sources for tissue-engineered vascular patches
    • Williams C., Xie A.W., Emani S., Yamato M., Okano T., Emani S.M., et al. A comparison of human smooth muscle and mesenchymal stem cells as potential cell sources for tissue-engineered vascular patches. Tissue Eng Part A 2012, 18:986-998.
    • (2012) Tissue Eng Part A , vol.18 , pp. 986-998
    • Williams, C.1    Xie, A.W.2    Emani, S.3    Yamato, M.4    Okano, T.5    Emani, S.M.6
  • 35
    • 1542344006 scopus 로고    scopus 로고
    • Expression, regulation, and function of IGF-1, IGF-1R, and IGF-1 binding proteins in blood vessels
    • Delafontaine P., Song Y.H., Li Y. Expression, regulation, and function of IGF-1, IGF-1R, and IGF-1 binding proteins in blood vessels. Arterioscler Thromb Vasc Biol 2004, 24:435-444.
    • (2004) Arterioscler Thromb Vasc Biol , vol.24 , pp. 435-444
    • Delafontaine, P.1    Song, Y.H.2    Li, Y.3
  • 36
    • 58149347238 scopus 로고    scopus 로고
    • Paracrine mechanisms in adult stem cell signaling and therapy
    • Gnecchi M., Zhang Z., Ni A., Dzau V.J. Paracrine mechanisms in adult stem cell signaling and therapy. Circ Res 2008, 103:1204-1219.
    • (2008) Circ Res , vol.103 , pp. 1204-1219
    • Gnecchi, M.1    Zhang, Z.2    Ni, A.3    Dzau, V.J.4
  • 37
    • 77950890007 scopus 로고    scopus 로고
    • Relative roles of direct regeneration versus paracrine effects of human cardiosphere-derived cells transplanted into infarcted mice
    • Chimenti I., Smith R.R., Li T.S., Gerstenblith G., Messina E., Giacomello A., et al. Relative roles of direct regeneration versus paracrine effects of human cardiosphere-derived cells transplanted into infarcted mice. Circ Res 2010, 106:971-980.
    • (2010) Circ Res , vol.106 , pp. 971-980
    • Chimenti, I.1    Smith, R.R.2    Li, T.S.3    Gerstenblith, G.4    Messina, E.5    Giacomello, A.6
  • 38
    • 84856287996 scopus 로고    scopus 로고
    • Three-dimensional cell grafting enhances the angiogenic efficacy of human umbilical vein endothelial cells
    • Bhang S.H., Lee S., Lee T.J., La W.G., Yang H.S., Cho S.W., et al. Three-dimensional cell grafting enhances the angiogenic efficacy of human umbilical vein endothelial cells. Tissue Eng Part A 2012, 18:310-319.
    • (2012) Tissue Eng Part A , vol.18 , pp. 310-319
    • Bhang, S.H.1    Lee, S.2    Lee, T.J.3    La, W.G.4    Yang, H.S.5    Cho, S.W.6
  • 39
    • 77950986580 scopus 로고    scopus 로고
    • Transforming growth factor-beta and notch signaling mediate stem cell differentiation into smooth muscle cells
    • Kurpinski K., Lam H., Chu J., Wang A., Kim A., Tsay E., et al. Transforming growth factor-beta and notch signaling mediate stem cell differentiation into smooth muscle cells. Stem Cells 2010, 28:734-742.
    • (2010) Stem Cells , vol.28 , pp. 734-742
    • Kurpinski, K.1    Lam, H.2    Chu, J.3    Wang, A.4    Kim, A.5    Tsay, E.6
  • 40
    • 0034654497 scopus 로고    scopus 로고
    • Controlling TGF-beta signaling
    • Massague J., Chen Y.G. Controlling TGF-beta signaling. Genes Dev 2000, 14:627-644.
    • (2000) Genes Dev , vol.14 , pp. 627-644
    • Massague, J.1    Chen, Y.G.2
  • 41
    • 21744461891 scopus 로고    scopus 로고
    • Forced myocardin expression primes cardiac and smooth muscle transcription patterning in human mesenchymal stem cells
    • Ventura C. Forced myocardin expression primes cardiac and smooth muscle transcription patterning in human mesenchymal stem cells. Cardiovasc Res 2005, 67:182-183.
    • (2005) Cardiovasc Res , vol.67 , pp. 182-183
    • Ventura, C.1
  • 42
    • 47149102903 scopus 로고    scopus 로고
    • Bone marrow-derived mesenchymal stem cells facilitate engineering of long-lasting functional vasculature
    • Au P., Tam J., Fukumura D., Jain R.K. Bone marrow-derived mesenchymal stem cells facilitate engineering of long-lasting functional vasculature. Blood 2008, 111:4551-4558.
    • (2008) Blood , vol.111 , pp. 4551-4558
    • Au, P.1    Tam, J.2    Fukumura, D.3    Jain, R.K.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.