Three-dimensional cell grafting enhances the angiogenic efficacy of human umbilical vein endothelial cells

Tissue Engineering - Part A

Volumn 18, Issue 3-4, 2012, Pages 310-319

  Bhang, Suk Ho ^a   Lee, Seahyoung ^a   Lee, Tae Jin ^b   La, Wan Geun ^a   Yang, Hee Seok ^b   Cho, Seung Woo ^c   Kim, Byung Soo ^a  

^a Seoul National University   (South Korea)

^b Hanyang University   (South Korea)

^c Yonsei University   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

CELL CULTURE; CELL DEATH; DISEASE CONTROL; MAMMALS; MONOLAYERS; PHYSIOLOGY; TISSUE;

ANGIOGENESIS; ATHYMIC MICE; CELL SURVIVAL; CELL THERAPY; ENGRAFTMENT; HIND LIMBS; HUMAN UMBILICAL VEIN ENDOTHELIAL CELLS; HYPOXIA-INDUCIBLE FACTOR 1; ISCHEMIC LIMBS; ISCHEMIC TISSUES; MONOLAYER CULTURE; PARACRINE; PROGENITOR CELL; THERAPEUTIC METHOD;

ENDOTHELIAL CELLS;

MUS; MUS MUSCULUS;

ANGIOGENIC FACTOR;

ANGIOGENESIS; ANIMAL; ARTICLE; CELL SURVIVAL; CYTOLOGY; EXTRACELLULAR MATRIX; HINDLIMB; HUMAN; ISCHEMIA; ISCHEMIC PRECONDITIONING; METABOLISM; METHODOLOGY; MOUSE; MULTICELLULAR SPHEROID; PATHOLOGY; SECRETION; TISSUE ENGINEERING; TRANSPLANTATION; UMBILICAL VEIN ENDOTHELIAL CELL; VASCULARIZATION;

ANGIOGENESIS INDUCING AGENTS; ANIMALS; CELL SURVIVAL; EXTRACELLULAR MATRIX; HINDLIMB; HUMAN UMBILICAL VEIN ENDOTHELIAL CELLS; HUMANS; ISCHEMIA; ISCHEMIC PRECONDITIONING; MICE; NEOVASCULARIZATION, PHYSIOLOGIC; SPHEROIDS, CELLULAR; TISSUE ENGINEERING;

EID: 84856287996     PISSN: 19373341     EISSN: 1937335X     Source Type: Journal    
DOI: 10.1089/ten.tea.2011.0193     Document Type: Article

References (34)

1. Chekanov, V., Akhtar, M., Tchekanov, G., Dangas, G., Shehzad, M.Z., Tio, F., Adamian, M., Colombo, A., Roubin, G., Leon, M.B., Moses, J.W., and Kipshidze, N.N. Transplantation of autologous endothelial cells induces angiogenesis. Pacing Clin Electrophysiol 26, 496, 2003.
2. Kim, E.J., Li, R.K., Weisel, R.D., Mickle, D.A., Jia, Z.Q., Tomita, S., Sakai, T., and Yau, T.M. Angiogenesis by endothelial cell transplantation. J Thorac Cardiovasc Surg 122, 963, 2001.
3. Calvani, M., Rapisarda, A., Uranchimeg, B., Shoemaker, R.H., and Melillo, G. Hypoxic induction of an HIF-1alphadependent bFGF autocrine loop drives angiogenesis in human endothelial cells. Blood 107, 2705, 2006.
4. Zhang, M., Methot, D., Poppa, V., Fujio, Y., Walsh, K., and Murry, C.E. Cardiomyocyte grafting for cardiac repair: graft cell death and anti-death strategies. J Mol Cell Cardiol 33, 907, 2001.
5. Nakamura, Y., Yasuda, T., Weisel, R.D., and Li, R.K. Enhanced cell transplantation: preventing apoptosis increases cell survival and ventricular function. Am J Physiol Heart Circ Physiol 291, H939, 2006.
6. Hu, X., Yu, S.P., Fraser J.L., Lu, Z., Ogle, M.E., Wang, J.A., and Wei, L. Transplantation of hypoxia-preconditioned mesenchymal stem cells improves infracted heart function via enhanced survivial of implanted cells and angiogenesis. J Thorac Cardiovasc Surg 135, 799, 2008.
7. Stempien-Otero, A., Karsan, A., Cornejo, C.J., Xiang, H., Eunson, T., Morrison, R.S., Kay, M., Winn, R., and Harlan, J. Mechanisms of hypoxia-induced endothelial cell death. J Biol Chem 274, 8039, 1999.
8. Korff, T., and Augustin, H.G. Integration of endothelial cells in multicellular spheroids prevents apoptosis and induces differentiation. J Cell Biol 143, 1341, 1998.
9. Alajati, A., Laib, A.M., Weber, H., Boos, A.M., Bartol, A., Ikenberg, K., Korff, T., Zentgraf, H., Obodozie, C., Graeser, R., Christian, S., Finkenzeller, G., Stark, G.B., Heroult, M., and Augustin, H. Spheroid-based engineering of a human vasculature in mice. Nat Methods 5, 439, 2008.
10. Land, S.C., and Rae, C. iNOS initiates and sustains metabolic arrest in hypoxic lung adenocarcinoma cells: mechanism of cell survival in solid tumor core. Am J Physiol Cell Physiol 289, C918, 2005.
11. Pugh, C.W., and Ratcliffe, P.J. Regulation of angiogenesis by hypoxia: role of the HIF system. Nat Med 9, 677, 2003.
12. Chen, C.S., Mrksich, M., Huang, S., Whitesides, G.M., and Ingber, D.E. Geometric control of cell life and death. Science 276, 1425, 1997.
13. Lelièvre, S.A., Weaver, V.M., Nickerson, J.A., Larabell, C.A., Bhaumik, A., Petersen, O.W., and Bissell, M.J. Tissue phenotype depends on reciprocal interactions between the extracellular matrix and the structural organization of the nucleus. Proc Natl Acad Sci USA 95, 14711, 1998.
14. Frisch, S.M., and Francis, H. Disruption of epithelial cellmatrix interactions induces apoptosis. J Cell Biol 124, 619, 1994.
15. Frisch, S.M., and Screaton, R.A. Anoikis mechanisms. Curr Opin Cell Biol 13, 555, 2001.
16. Bhang, S.H., Cho, S.W., Lim, J.M., Kang, J.M., Lee, T.J., Yang, H.S., Song, Y.S., Park, M.H., Kim, H.S., Yoo, K.J., Jang, Y, Langer, R., Anderson, D.G., and Kim, B.S. Locally-delivered growth factor enhances the angiogenic efficacy of adiposederived stromal cells transplanted to ischemic limbs. Stem Cells 27, 1976, 2009.
17. Bhang, S.H., Cho, S.W., La, W.G., Lee, T.J., Yang, H.S., Sun, A.Y., Baek, S.H., Rhie, J.W., and Kim, B.S. Angiogenesis in ischemic tissue produced by spheroid grafting of human adiopose-derived stromal cells. Biomaterials 32, 2734, 2011.
18. Cho, S.W., Moon, S.H., Lee, S.H., Kang, S.W., Kim, J., Lim, J.M., Kim, H.S., Kim, B.S., and Chung, H.M. Improvement of postnatal neovascularization by human embryonic stem cell derived endothelial-like cell transplantation in a mouse model of hindlimb ischemia. Circulation 116, 2409, 2007.
19. Wu, L.W., Mayo, L.D., Dunbar, J.D., Kessler, K.M., Baerwald, M.R., Jaffe, E.A., Wang, D., Warren, R.S., and Donner, D.B. Utilization of distinct signaling pathways by receptors for vascular endothelial cell growth factor and other mitogens in the induction of endothelial cell proliferation. J Biol Chem 275, 5096, 2000.
20. Ye, L., Haider, H.K., Jiang, S.J., and Sim, E.K. Therapeutic angiogenesis using vascular endothelial growth factor. Asian Cardiovasc Thorac Ann 12, 173, 2004.
21. Bernaudin, M., Nedelec, A.S., Divoux, D., MacKenzie, E.T., Petit, E., and Schumann-Bard, P. Normobaric hypoxia induces tolerance to focal permanent cerebral ischemia in association with an increased expression of hypoxia-inducible factor-1 and its target genes, erythropoietin and VEGF, in the adult mouse brain. J Cereb Blood Flow Metab 4, 393, 2002.
22. Ma, D., Lim, T., Xu, J., Tang, H., Wan, Y., Zhao, H., Hossain, M., Maxwell, P.H., and Maze, M. Xenon preconditioning protects against renal ischemic-reperfusion injury via HIF-1alpha activation. J Am Soc Nephrol 20, 713, 2009.
23. De Vries, C., Escobedo, J.A., Ueno, H., Houck, K., Ferrara, N., and Williams, L.T. The fms-like tyrosine kinase, a receptor for vascular endothelial growth factor. Science 255, 989, 1992.
24. Nunez, G., and del Peso, L. Linking extracellular survival signals and the apoptotic machinery. Curr Opin Neurobiol 8, 613, 1998.
25. Cai, J., Ahmad, S., Jiang, W.G., Huang, J., Kontos, C.D., Boulton, M., and Ahmed, A. Activation of vascular endothelial growth factor receptor-1 sustains angiogenesis and Bcl-2 expression via the phosphatidylinositol 3-kinase pathway in endothelial cells. Diabetes 52, 2959, 2003.
26. Hutchings, H., Ortega, N., and Plouet, J. Extracellular matrix-bound vascular endothelial growth factor promotes endothelial cell adhesion, migration and survival through integrin ligation. FASEB J 17, 1520, 2003.
27. Marti, H.H., and Risau, W. Systemic hypoxia changes the organspecific distribution of vascular endothelial growth factor and its receptors. Proc Natl Acad Sci USA 95, 15809, 1998.
28. Munoz-Chapuli, R., Quesada, A.R., and Medina, M.A. Angiogenesis and signal transduction in endothelial cells. Cell Mol Life Sci 61, 2224, 2004.
29. Nor, J.E., Christensen, J., Mooney, D.J., and Polverini, P.J. Vascular endothelial growth factor (VEGF)-mediated angiogenesis is associated with enhanced endothelial cell survival and induction of Bcl-2 expression. Am J Pathol 154, 375, 1999.
30. Bouchentouf, M., Benabdallah, B.F., Rousseau, J., Schwartz, L.M., and Tremblay, J.P. Induction of anoikis following myoblast transplantation into SCID mouse muscles requires the Bit1 and FADD pathways. Am J Transplant 7, 1491, 2007.
31. Grossmann, J. Molecular mechanisms of "detachmentinduced apoptosis-Anoikis." Apoptosis 7, 247, 2002.
32. Yoon, C.H., Hur, J., Oh, I.Y., Park, K.W., Kim, T.Y., Shin, J.H., Kim, J.H., Lee, C.S., Chung, J.K., Park, Y.B., and Kim, H.S. Intercellular adhesion molecule-1 is upregulated in ischemic muscle, which mediates trafficking of endothelial progenitor cells. Artheioscler Thromb Vasc Biol 26, 1066, 2006.
33. Gaengel, K., Genové, G., Armulik, A., and Betsholtz, C. Endothelial-mural cell signaling in vascular development and angiogenesis. Arterioscler Thromb Vasc Biol 29, 630, 2009.
34. Kvanta, A., Sarman, S., Fagerholm, P., Seregard, S., and Steen, B. Expression of matrix metalloproteinase-2 (MMP-2) and vascular endothelial growth factor (VEGF) in inflammation-associated corneal neovascularization. Exp Eye Res 70, 419, 2000.