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Volumn 11, Issue 12, 2012, Pages 2654-2663

Targeting the inhibitor of apoptosis proteins as a novel therapeutic strategy in medulloblastoma

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; CASPASE 8; CASPASE 9; CISPLATIN; INHIBITOR OF APOPTOSIS PROTEIN; LBW 242; UNCLASSIFIED DRUG; VINCRISTINE;

EID: 84871390666     PISSN: 15357163     EISSN: 15388514     Source Type: Journal    
DOI: 10.1158/1535-7163.MCT-12-0352     Document Type: Article
Times cited : (11)

References (29)
  • 2
    • 0037261086 scopus 로고    scopus 로고
    • Advances in the diagnosis, molecular genetics, and treatment of pediatric embryonal CNS tumors
    • DOI 10.1634/theoncologist.8-2-174
    • MacDonald TJ, Rood BR, Santi MR, Vezina G, Bingaman K, Cogen PH, et al. Advances in the diagnosis, molecular genetics, and treatment of pediatric embryonal CNS tumors. Oncologist 2003;8:174-86. (Pubitemid 36428283)
    • (2003) Oncologist , vol.8 , Issue.2 , pp. 174-186
    • MacDonald, T.J.1    Rood, B.R.2    Santi, M.R.3    Vezina, G.4    Bingaman, K.5    Cogen, P.H.6    Packer, R.J.7
  • 4
    • 79954991010 scopus 로고    scopus 로고
    • Integrative genomic analysis of medulloblastoma identifies a molecular subgroup that drives poor clinical outcome
    • Cho Y-J, Tsherniak A, Tamayo P, Santagata S, Ligon A, Greulich H, et al. Integrative genomic analysis of medulloblastoma identifies a molecular subgroup that drives poor clinical outcome. J Clin Oncol 2011;29:1424-30.
    • (2011) J Clin Oncol , vol.29 , pp. 1424-1430
    • Cho, Y.-J.1    Tsherniak, A.2    Tamayo, P.3    Santagata, S.4    Ligon, A.5    Greulich, H.6
  • 5
    • 79954992066 scopus 로고    scopus 로고
    • Definition of disease-risk stratification groups in childhood medulloblastoma using combined clinical, pathologic, and molecular variables
    • Ellison DW, Kocak M, Dalton J, Megahed H, Lusher ME, Ryan SL, et al. Definition of disease-risk stratification groups in childhood medulloblastoma using combined clinical, pathologic, and molecular variables. J Clin Oncol 2011;29:1400-7.
    • (2011) J Clin Oncol , vol.29 , pp. 1400-1407
    • Ellison, D.W.1    Kocak, M.2    Dalton, J.3    Megahed, H.4    Lusher, M.E.5    Ryan, S.L.6
  • 6
    • 28544445217 scopus 로고    scopus 로고
    • High-dose busulfan and thiotepa followed by autologous stem cell transplantation (ASCT) In previously irradiated medulloblastoma patients: High toxicity and lack of efficacy
    • DOI 10.1038/sj.bmt.1705162, PII 1705162
    • Valteau-Couanet D, Fillipini B, Benhamou E, Grill J, Kalifa C, Couanet D, et al. High-dose busulfan and thiotepa followed by autologous stem cell transplantation (ASCT) in previously irradiated medulloblastoma patients: high toxicity and lack of efficacy. Bone Marrow Transplant 2005;36:939-45. (Pubitemid 41741555)
    • (2005) Bone Marrow Transplantation , vol.36 , Issue.11 , pp. 939-945
    • Valteau-Couanet, D.1    Fillipini, B.2    Benhamou, E.3    Grill, J.4    Kalifa, C.5    Couanet, D.6    Habrand, J.L.7    Hartmann, O.8
  • 9
    • 0347601880 scopus 로고    scopus 로고
    • A decade of caspases
    • DOI 10.1038/sj.onc.1207107
    • Degterev A, Boyce M, Yuan J. A decade of caspases. Oncogene 2003;22:8543-67. (Pubitemid 38028527)
    • (2003) Oncogene , vol.22 , Issue.53 REV. ISS. 7 , pp. 8543-8567
    • Degterev, A.1    Boyce, M.2    Yuan, J.3
  • 10
    • 1542357606 scopus 로고    scopus 로고
    • Apoptosis pathways in cancer and cancer therapy
    • Debatin K-M. Apoptosis pathways in cancer and cancer therapy. Cancer Immunol Immunother 2004;53:153.
    • (2004) Cancer Immunol Immunother , vol.53 , pp. 153
    • Debatin, K.-M.1
  • 11
    • 10044282921 scopus 로고    scopus 로고
    • Apoptosis pathway-targeted drugs -from the bench to the clinic
    • Cummings J, Ward TH, Ranson M, Dive C. Apoptosis pathway-targeted drugs -from the bench to the clinic. Biochim Biophys Acta 2004;1705:53.
    • (2004) Biochim Biophys Acta , vol.1705 , pp. 53
    • Cummings, J.1    Ward, T.H.2    Ranson, M.3    Dive, C.4
  • 12
    • 0038013875 scopus 로고    scopus 로고
    • Senescence, apoptosis and therapy - Cutting the lifelines of cancer
    • Schmitt CA. Senescence, apoptosis and therapy - cutting the lifelines of cancer. Nat Rev Cancer 2003;3:286.
    • (2003) Nat Rev Cancer , vol.3 , pp. 286
    • Schmitt, C.A.1
  • 13
    • 0041853572 scopus 로고    scopus 로고
    • Inhibition of neuroepithelial patched-induced apoptosis by Sonic hedgehog
    • DOI 10.1126/science.1085405
    • Thibert C, Teillet MA, Lapointe F, Mazelin L, Le Douarin NM, Mehlen P. Inhibition of neuroepithelial patched-induced apoptosis by sonic hedgehog. Science 2003;301:843-6. (Pubitemid 36962627)
    • (2003) Science , vol.301 , Issue.5634 , pp. 843-846
    • Thibert, C.1    Teillet, M.-A.2    Lapointe, F.3    Mazelin, L.4    Le, D.N.M.5    Mehlen, P.6
  • 14
    • 34347241369 scopus 로고    scopus 로고
    • Apoptosis suppression by somatic cell transfer of Bcl-2 promotes Sonic hedgehog-dependent medulloblastoma formation in mice
    • DOI 10.1158/0008-5472.CAN-06-4177
    • McCall TD, Pedone CA, Fults DW. Apoptosis suppression by somatic cell transfer of bcl-2 promotes sonic hedgehog-dependent medulloblastoma formation in mice. Cancer Res 2007;67:5179-85. (Pubitemid 46997255)
    • (2007) Cancer Research , vol.67 , Issue.11 , pp. 5179-5185
    • McCall, T.D.1    Pedone, C.A.2    Fults, D.W.3
  • 15
    • 0031762951 scopus 로고    scopus 로고
    • Activation of the CD95 (APO-1/Fas) pathway in drug- And gamma-irradiation-induced apoptosis of brain tumor cells
    • Fulda S, Scaf fidi C, Pietsch T, Krammer PH, Peter ME, Debatin KM. Activation of the CD95 (APO-1/Fas) pathway in drug- and gamma-irradiation- induced apoptosis of brain tumor cells. Cell Death Differ 1998;5:884-93.
    • (1998) Cell Death Differ , vol.5 , pp. 884-893
    • Fulda, S.1    Scaf Fidi, C.2    Pietsch, T.3    Krammer, P.H.4    Peter, M.E.5    Debatin, K.M.6
  • 16
    • 14844321871 scopus 로고    scopus 로고
    • Survivin, Survivin-2B, and Survivin-deltaEx3 expression in medulloblastoma: Biologic markers of tumour morphology and clinical outcome
    • DOI 10.1038/sj.bjc.6602317
    • Fangusaro JR, Jiang Y, Holloway MP, Caldas H, Singh V, Boue DR, et al. Survivin, Survivin-2B, and Survivin-deItaEx3 expression in medulloblastoma: biologic markers of tumour morphology and clinical outcome. Br J Cancer 2005;92:359-65. (Pubitemid 40343153)
    • (2005) British Journal of Cancer , vol.92 , Issue.2 , pp. 359-365
    • Fangusaro, J.R.1    Jiang, Y.2    Holloway, M.P.3    Caldas, H.4    Singh, V.5    Boue, D.R.6    Hayes, J.7    Altura, R.A.8
  • 19
    • 37549000486 scopus 로고    scopus 로고
    • A Smac mimetic rescue screen reveals roles for inhibitor of apoptosis proteins in tumor necrosis factor-alpha signaling
    • Gaither A, Porter D, Yao Y, Borawski J, Yang G, Donovan J, et al. A Smac mimetic rescue screen reveals roles for inhibitor of apoptosis proteins in tumor necrosis factor-alpha signaling. Cancer Res 2007;67:11493-8.
    • (2007) Cancer Res , vol.67 , pp. 11493-11498
    • Gaither, A.1    Porter, D.2    Yao, Y.3    Borawski, J.4    Yang, G.5    Donovan, J.6
  • 21
    • 80052731000 scopus 로고    scopus 로고
    • A small-molecule IAP inhibitor overcomes resistance to cytotoxic therapies in malignant gliomas in vitro and in vivo
    • Ziegler DS, Keating J, Kesari S, Fast EM, Zawel L, Ramakrishna N, et al. A small-molecule IAP inhibitor overcomes resistance to cytotoxic therapies in malignant gliomas in vitro and in vivo. Neurooncol 2011;13:820-9.
    • (2011) Neurooncol , vol.13 , pp. 820-829
    • Ziegler, D.S.1    Keating, J.2    Kesari, S.3    Fast, E.M.4    Zawel, L.5    Ramakrishna, N.6
  • 22
    • 51349124367 scopus 로고    scopus 로고
    • Resistance of human glioblastoma multiforme cells to growth factor inhibitors is overcome by blockade of inhibitor of apoptosis proteins
    • Ziegler DS, Wright RD, Kesari S, Lemieux ME, Tran MA, Jain M, et al. Resistance of human glioblastoma multiforme cells to growth factor inhibitors is overcome by blockade of inhibitor of apoptosis proteins. J Clin Invest 2008;118:3109-22.
    • (2008) J Clin Invest , vol.118 , pp. 3109-3122
    • Ziegler, D.S.1    Wright, R.D.2    Kesari, S.3    Lemieux, M.E.4    Tran, M.A.5    Jain, M.6
  • 23
    • 0021118703 scopus 로고
    • Quantitative analysis of dose-effect relationships: The combined effects of multiple drugs or enzyme inhibitors
    • Chou TC, Talalay P. Quantitative analysis of dose-effect relationships: the combined effects of multiple drugs or enzyme inhibitors. Adv Enzyme Regul 1984;22:27-55.
    • (1984) Adv Enzyme Regul , vol.22 , pp. 27-55
    • Chou, T.C.1    Talalay, P.2
  • 26
    • 0036341291 scopus 로고    scopus 로고
    • Smac agonists sensitize for Apo2L/TRAIL- Or anticancer drug-induced apoptosis and induce regression of malignant glioma in vivo
    • Fulda S, Wick W, Weller M, Debatin KM. Smac agonists sensitize for Apo2L/TRAIL- or anticancer drug-induced apoptosis and induce regression of malignant glioma in vivo . Nat Med 2002;8:808-15.
    • (2002) Nat Med , vol.8 , pp. 808-815
    • Fulda, S.1    Wick, W.2    Weller, M.3    Debatin, K.M.4
  • 28
    • 36549070757 scopus 로고    scopus 로고
    • Therapeutic targeting of apoptosis pathways in cancer
    • DOI 10.1097/CCO.0b013e3282f310f6, PII 0000162220080100000015
    • Ziegler DS, Kung AL. Therapeutic targeting of apoptosis pathways in cancer. Curr Opin Oncol 2008;20:97-103. (Pubitemid 350190988)
    • (2008) Current Opinion in Oncology , vol.20 , Issue.1 , pp. 97-103
    • Ziegler, D.S.1    Kung, A.L.2
  • 29
    • 84861151960 scopus 로고    scopus 로고
    • Smac mimetic LBW242 sensitizes XIAP-overexpressing neuroblastoma cells for TNF-α-independent apoptosis
    • Eschenburg G, Eggert A, Schramm A, Lode HN, Hundsdoerfer P. Smac mimetic LBW242 sensitizes XIAP-overexpressing neuroblastoma cells for TNF-α-independent apoptosis. Cancer Res 2012;72:2645-56.
    • (2012) Cancer Res , vol.72 , pp. 2645-2656
    • Eschenburg, G.1    Eggert, A.2    Schramm, A.3    Lode, H.N.4    Hundsdoerfer, P.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.