A small-molecule IAP inhibitor overcomes resistance to cytotoxic therapies in malignant gliomas in vitro and in vivo

Neuro-Oncology

Volumn 13, Issue 8, 2011, Pages 820-829

  Ziegler, David S ^a,f,g   Keating, Joanna ^f   Kesari, Santosh ^a,b,h   Fast, Eva M ^a,b,i   Zawel, Leigh ^e,k   Ramakrishna, Naren ^a,b,j   Barnes, Jessica ^c   Kieran, Mark W ^a,c,d   Van Zanten, Sophie E M Veldhuijzen ^a   Kung, Andrew L ^a,d  

^a DANA FARBER CANCER INSTITUTE   (United States)

^b BRIGHAM AND WOMEN S HOSPITAL   (United States)

^c HARVARD MEDICAL SCHOOL   (United States)

^d BOSTON CHILDREN S HOSPITAL   (United States)

^e NOVARTIS INSTITUTES FOR BIOMEDICAL RESEARCH   (United States)

^f UNIVERSITY OF NEW SOUTH WALES   (Australia)

^g SYDNEY CHILDREN'S HOSPITAL   (Australia)

^h UNIVERSITY OF CALIFORNIA   (United States)

ⁱ Boston University   (United States)

^j M D ANDERSON CANCER CENTER ORLANDO   (United States)

^k MERCK RESEARCH LABORATORIES   (United States)

more..

Author keywords

Apoptosis; Glioma; Inhibitor of Apoptosis Protein; Radiotherapy

Indexed keywords

ANTINEOPLASTIC AGENT; CASPASE 8; CASPASE 9; INHIBITOR OF APOPTOSIS PROTEIN INHIBITOR; LBW 242; TEMOZOLOMIDE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CANCER GROWTH; CANCER RADIOTHERAPY; CONTROLLED STUDY; CYTOTOXICITY; GLIOBLASTOMA; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; MOUSE; NONHUMAN; TREATMENT DURATION; XENOGRAFT;

ANIMALS; ANTINEOPLASTIC AGENTS; APOPTOSIS; BLOTTING, WESTERN; BRAIN NEOPLASMS; CELL LINE, TUMOR; CELL PROLIFERATION; COMBINED MODALITY THERAPY; DACARBAZINE; GAMMA RAYS; GLIOMA; HUMANS; INHIBITOR OF APOPTOSIS PROTEINS; MICE; MICE, NUDE; OLIGOPEPTIDES; RADIATION-SENSITIZING AGENTS; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 80052731000     PISSN: 15228517     EISSN: 15235866     Source Type: Journal    
DOI: 10.1093/neuonc/nor066     Document Type: Article

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