Micelles of zinc protoporphyrin conjugated to N-(2-hydroxypropyl) methacrylamide (HPMA) copolymer for imaging and light-induced antitumor effects in vivo

Journal of Controlled Release

Volumn 165, Issue 3, 2013, Pages 191-198

  Nakamura, Hideaki ^a   Liao, Long ^a   Hitaka, Yuki ^a   Tsukigawa, Kenji ^a   Subr, Vladimir ^b   Fang, Jun ^a   Ulbrich, Karel ^b   Maeda, Hiroshi ^a  

^a SOJO UNIVERSITY   (Japan)

^b INSTITUTE OF MACROMOLECULAR CHEMISTRY   (Czech Republic)

Author keywords

EPR effect; Fluorescence imaging; Fluorescent nanoprobe; HPMA ZnPP conjugate; Keywords; Singlet oxygen; Tumor targeting

Indexed keywords

EPR EFFECT; FLUORESCENCE IMAGING; HPMA-ZNPP CONJUGATE; KEYWORDS; SINGLET OXYGEN; TUMOR TARGETING;

CONJUGATED POLYMERS; CYTOTOXICITY; ENDOSCOPY; FLUORESCENCE; IRRADIATION; MAMMALS; MICELLES; NANOPROBES; OXYGEN;

TUMORS;

COPOLYMER; N (2 HYDROXYPROPYL)METHACRYLAMIDE; PROTOPORPHYRIN ZINC;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER DIAGNOSIS; CONTROLLED STUDY; DRUG CONJUGATION; DRUG STABILITY; ENDOSCOPY; FLUORESCENCE IMAGING; HELA CELL; HUMAN; HUMAN CELL; HYDROPHOBICITY; IRRADIATION; LIGHT EXPOSURE; MALE; MICELLE; MICELLIZATION; MOUSE; NANOPROBE; NONHUMAN; PARTICLE SIZE; PHOTOCHEMISTRY; PLASMA HALF LIFE; PRIORITY JOURNAL; SURFACE CHARGE; TISSUE DISTRIBUTION; TUMOR GROWTH;

ACRYLAMIDES; ANIMALS; ANTINEOPLASTIC AGENTS; CELL LINE, TUMOR; CELL SURVIVAL; HELA CELLS; HUMANS; LIGHT; MALE; MICE; MICELLES; NEOPLASMS; OPTICAL IMAGING; PHOTOCHEMOTHERAPY; PHOTOSENSITIZING AGENTS; PROTOPORPHYRINS; TUMOR BURDEN;

EID: 84871361336     PISSN: 01683659     EISSN: 18734995     Source Type: Journal    
DOI: 10.1016/j.jconrel.2012.11.017     Document Type: Article

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