Cdx1 and c-Myc foster the initiation of transdifferentiation of the normal esophageal squamous epithelium toward Barrett's esophagus

PLoS ONE

Volumn 3, Issue 10, 2008, Pages

  Stairs, Douglas B ^a   Nakagawa, Hiroshi ^a   Klein Szanto, Andres ^b   Mitchell, Shukriyyah D ^a   Silberg, Debra G ^a   Tobias, John W ^a   Lynch, John P ^a   Rustgi, Anil K ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b FOX CHASE CANCER CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

MYC PROTEIN; TRANSCRIPTION FACTOR CDX1; BIOLOGICAL MARKER; CDX1 PROTEIN, HUMAN; HOMEODOMAIN PROTEIN; MYC PROTEIN, HUMAN; UNCLASSIFIED DRUG;

ARTICLE; BARRETT ESOPHAGUS; CELL DIFFERENTIATION; CONTROLLED STUDY; CULTURE TECHNIQUE; DISEASE COURSE; ESOPHAGUS MUCOSA; GENE EXPRESSION; GENE FUNCTION; GENE IDENTIFICATION; GENETIC ASSOCIATION; HUMAN; HUMAN TISSUE; INTESTINE BIOPSY; KERATINOCYTE; MICROARRAY ANALYSIS; NUCLEOTIDE SEQUENCE; SIGNAL TRANSDUCTION; SQUAMOUS EPITHELIUM; TRANSCRIPTION INITIATION; CELL CULTURE; CELL TRANSDIFFERENTIATION; CLUSTER ANALYSIS; COMPARATIVE STUDY; DNA MICROARRAY; ESOPHAGUS; ESOPHAGUS TUMOR; GENE EXPRESSION PROFILING; GENETICS; METABOLISM; PATHOLOGY; PHYSIOLOGY; PRECANCER; SQUAMOUS CELL CARCINOMA;

BARRETT ESOPHAGUS; BIOLOGICAL MARKERS; CARCINOMA, SQUAMOUS CELL; CELL TRANSDIFFERENTIATION; CELLS, CULTURED; CLUSTER ANALYSIS; ESOPHAGEAL NEOPLASMS; ESOPHAGUS; GENE EXPRESSION PROFILING; HOMEODOMAIN PROTEINS; HUMANS; KERATINOCYTES; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PRECANCEROUS CONDITIONS; PROTO-ONCOGENE PROTEINS C-MYC;

EID: 55849117334     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0003534     Document Type: Article

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