SOX9 is expressed in normal stomach, intestinal metaplasia, and gastric carcinoma in humans

Journal of Gastroenterology

Volumn 46, Issue 11, 2011, Pages 1292-1299

  Sashikawa Kimura, Miho ^a   Mutoh, Hiroyuki ^a   Sugano, Kentaro ^a  

^a JICHI MEDICAL UNIVERSITY   (Japan)

Author keywords

Gastric carcinoma; Intestinal metaplasia; SOX9; Stomach

Indexed keywords

TRANSCRIPTION FACTOR SOX9;

ARTICLE; CELLULAR DISTRIBUTION; CONTROLLED STUDY; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; INTESTINE METAPLASIA; PRECANCER; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; STOMACH CARCINOMA;

BIOLOGICAL MARKERS; CELL PROLIFERATION; DISEASE PROGRESSION; GENE EXPRESSION REGULATION, NEOPLASTIC; HELICOBACTER PYLORI; HUMANS; IMMUNOHISTOCHEMISTRY; INTESTINES; METAPLASIA; PROLIFERATING CELL NUCLEAR ANTIGEN; SOX9 TRANSCRIPTION FACTOR; STOMACH; STOMACH NEOPLASMS; TUMOR MARKERS, BIOLOGICAL;

EID: 84655163473     PISSN: 09441174     EISSN: 14355922     Source Type: Journal    
DOI: 10.1007/s00535-011-0443-5     Document Type: Article

References (22)

1. P Blache M van de Wetering I Duluc C Domon P Berta JN Freund H Clevers P Jay 2004 SOX9 is an intestine crypt transcription factor, is regulated by the Wnt pathway, and represses the CDX2 and MUC2 genes J Cell Biol 166 37 47 (Pubitemid 38931915)
2. P Jay P Berta P Blache 2005 Expression of the carcinoembryonic antigen gene is inhibited by SOX9 in human colon carcinoma cells Cancer Res 65 2193 2198 (Pubitemid 40490127)
3. P Bastide C Darido J Pannequin R Kist S Robine C Marty-Double F Bibeau G Scherer D Joubert F Hollande P Blache P Jay 2007 Sox9 regulates cell proliferation and is required for Paneth cell differentiation in the intestinal epithelium J Cell Biol 178 635 648 (Pubitemid 47267275)
4. T Reya H Clevers 2005 Wnt signalling in stem cells and cancer Nature 434 843 850 (Pubitemid 40558990)
5. B Moniot S Biau S Faure CM Nielsen P Berta DJ Roberts P de Santa Barbara 2004 SOX9 specifies the pyloric sphincter epithelium through mesenchymal-epithelial signals Development 131 3795 3804 (Pubitemid 39199386)
6. B Lu J Xu M Lai H Zhang J Chen 2006 A transcriptome anatomy of human colorectal cancers BMC Cancer 6 40
7. B Helpap T Hattori P Gedigk 1981 Repair of gastric ulcer. A cell kinetic study Virchows Arch A Pathol Anat Histol 392 159 170 (Pubitemid 11079043)
8. T Hattori B Helpap P Gedigk 1982 The morphology and cell kinetics of pseudopyloric glands Virchows Arch B Cell Pathol Incl Mol Pathol 39 31 40 (Pubitemid 12133306)
9. MF Dixon RM Genta JH Yardley P Correa 1996 Classification and grading of gastritis. The updated Sydney System. International workshop on the histopathology of gastritis, Houston 1994 Am J Surg Pathol 20 1161 1181
10. H Mutoh Y Hakamata K Sato A Eda I Yanaka S Honda H Osawa Y Kaneko K Sugano 2002 Conversion of gastric mucosa to intestinal metaplasia in Cdx2-expressing transgenic mice Biochem Biophys Res Commun 294 470 479 (Pubitemid 34694118)
11. H Mutoh K Satoh H Kita H Sakamoto H Hayakawa H Yamamoto N Isoda K Tamada K Ido K Sugano 2005 Cdx2 specifies the differentiation of morphological as well as functional absorptive enterocytes of the small intestine Int J Dev Biol 49 867 871 (Pubitemid 41503255)
12. P Correa MC Camargo MB Piazuelo 2008
13. P Correa 1992 Human gastric carcinogenesis: a multistep and multifactorial process-first American Cancer Society Award lecture on cancer epidemiology and prevention Cancer Res 52 6735 6740 (Pubitemid 23006271)
14. AD Gracz S Ramalingam ST Magness 2010 Sox9 expression marks a subset of CD24-expressing small intestine epithelial stem cells that form organoids in vitro Am J Physiol Gastrointest Liver Physiol 298 G590 G600
15. SS Jiang WT Fang YH Hou SF Huang BL Yen JL Chang SM Li HP Liu YL Liu CT Huang YW Li TH Jang SH Chan SJ Yang CA Hsiung CW Wu LH Wang IS Chang 2010 Upregulation of SOX9 in lung adenocarcinoma and its involvement in the regulation of cell growth and tumorigenicity Clin Cancer Res 16 4363 4373
16. T Reya SJ Morrison MF Clarke IL Weissman 2001 Stem cells, cancer, and cancer stem cells Nature 414 105 111 (Pubitemid 33041634)
17. M Quante TC Wang 2009 Stem cells in gastroenterology and hepatology Nat Rev Gastroenterol Hepatol 6 724 737
18. S Sell GB Pierce 1994 Maturation arrest of stem cell differentiation is a common pathway for the cellular origin of teratocarcinomas and epithelial cancers Lab Invest 70 6 22 (Pubitemid 24080100)
19. GB Pierce 1977 Neoplastic stem cells Adv Pathobiol. 6 141 152
20. NA Lobo Y Shimono D Qian MF Clarke 2007 The biology of cancer stem cells Annu Rev Cell Dev Biol 23 675 699
21. PN Kelly A Dakic JM Adams SL Nutt A Strasser 2007 Tumor growth need not be driven by rare cancer stem cells Science 317 337 (Pubitemid 47106366)
22. C Li DG Heidt P Dalerba CF Burant L Zhang V Adsay M Wicha MF Clarke DM Simeone 2007 Identification of pancreatic cancer stem cells Cancer Res 67 1030 1037