Hepatitis C virus impairs p53 via persistent overexpression of β-hydroxysterol Δ24-reductase

Journal of Biological Chemistry

Volumn 284, Issue 52, 2009, Pages 36442-36452

  Nishimura, Tomohiro ^a,b   Kohara, Michinori ^c   Izumi, Kosuke ^d   Kasama, Yuri ^a   Hirata, Yuichi ^c   Huang, Ying ^d,f   Shuda, Masahiro ^c,g   Mukaidani, Chise ^e   Takano, Takashi ^c   Tokunaga, Yuko ^a   Nuriya, Hideko ^c   Satoh, Masaaki ^a   Saito, Makoto ^a   Kai, Chieko ^d   Tsukiyama Kohara, Kyoko ^a  

^a KUMAMOTO UNIVERSITY   (Japan)

^b Chemo Sero Therapeutic Research Institute   (Japan)

^c TOKYO METROPOLITAN INSTITUTE OF MEDICAL SCIENCE   (Japan)

^d UNIVERSITY OF TOKYO   (Japan)

^e PhoenixBio USA Corporation   (Japan)

^f NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES   (United States)

^g UNIVERSITY OF PITTSBURGH CANCER INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLATION; AMINO ACIDS; CELL CULTURE; CELL DEATH; MONOCLONAL ANTIBODIES;

AFTER-TREATMENT; HEPATITIS C VIRUS; HUMAN HEPATOCYTES; LYSINE RESIDUES; OVER-EXPRESSION; PERSISTENT INFECTION; STRESS RESPONSE; UBIQUITIN LIGASES;

VIRUSES;

PROTEIN P53;

ACETYLATION; ARTICLE; CARCINOGENICITY; CONTROLLED STUDY; CYTOPLASM; DEREGULATION; GENE OVEREXPRESSION; HEPATITIS C; HEPATITIS C VIRUS; HEPATOBLASTOMA; HUMAN; HUMAN CELL; LIVER CELL; NONHUMAN; NUCLEOTIDE SEQUENCE; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN PHOSPHORYLATION; STRESS;

HEPATITIS C VIRUS;

EID: 73649087627     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M109.043232     Document Type: Article

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