Advances in acute and chronic pancreatitis: From development to inflammation and repair

Gastroenterology

Volumn 144, Issue 1, 2013, Pages

  Pasca Di Magliano, Marina ^a   Forsmark, Christopher ^b   Freedman, Steven ^c   Hebrok, Matthias ^d   Pasricha, Pankaj J ^e   Saluja, Ashok ^f   Stanger, Ben Z ^g   Holt, Jane ^h   Serrano, Jose ⁱ   James, Stephen P ⁱ   Rustgi, Anil K ^g  

^a UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

^b UNIVERSITY OF FLORIDA COLLEGE OF MEDICINE   (United States)

^c HARVARD MEDICAL SCHOOL   (United States)

^d UNIVERSITY OF CALIFORNIA   (United States)

^e JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^f UNIVERSITY OF MINNESOTA MEDICAL SCHOOL   (United States)

^g UNIVERSITY OF PENNSYLVANIA   (United States)

^h National Pancreas Foundation   (United States)

ⁱ NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BETA CATENIN; CRE RECOMBINASE; CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR; HEPATOCYTE NUCLEAR FACTOR 3BETA; INTERLEUKIN 6; STAT3 PROTEIN; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR GATA 4; TRANSCRIPTION FACTOR NR5A2; TRANSCRIPTION FACTOR PTF1A; TRANSCRIPTION FACTOR RBPJL; TRANSCRIPTION FACTOR SOX9; UNCLASSIFIED DRUG; WNT PROTEIN;

ACINAR CELL; ACUTE PANCREATITIS; CELL DEDIFFERENTIATION; CHRONIC PANCREATITIS; CONFERENCE PAPER; EXOCRINE CELL; GENETIC ASSOCIATION; GENETIC VARIABILITY; INFLAMMATION; MICROENVIRONMENT; MULTIPOTENT STEM CELL; NONHUMAN; ORGANOGENESIS; PATHOGENESIS; PHENOTYPIC PLASTICITY; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; WNT SIGNALING PATHWAY;

EID: 84871311767     PISSN: 00165085     EISSN: 15280012     Source Type: Journal    
DOI: 10.1053/j.gastro.2012.11.018     Document Type: Conference Paper

References (20)

1. J.L. Kopp, C.L. Dubois, A.E. Schaffer Sox9+ ductal cells are multipotent progenitors throughout development but do not produce new endocrine cells in the normal or injured adult pancreas Development 138 2011 653 665
2. M. Rovira, S.G. Scott, A.S. Liss Isolation and characterization of centroacinar/terminal ductal progenitor cells in adult mouse pancreas Proc Natl Acad Sci U S A 107 2010 75 80
3. S.R. Smukler, M.E. Arntfield, R. Razavi The adult mouse and human pancreas contain rare multipotent stem cells that express insulin Cell Stem Cell 8 2011 281 293
4. X. Molero, E.C. Vaquero, M. Flández Gene expression dynamics after murine pancreatitis unveils novel roles for Hnf1 in acinar cell homeostasis Gut 61 2012 1187 1196
5. X. Chen, M.D. Sans, J.R. Strahler Quantitative organellar proteomics analysis of rough endoplasmic reticulum from normal and acute pancreatitis rat pancreas J Proteome Res 9 2010 885 896
6. S. Pan, R. Chen, T. Stevens Proteomics portrait of archival lesions of chronic pancreatitis PLoS One 6 2011 e27574
7. S. Pan, R. Chen, D.A. Crispin Protein alterations associated with pancreatic cancer and chronic pancreatitis found in human plasma using global quantitative proteomics profiling J Proteome Res 10 2011 2359 2376
8. S. Gaiser, J. Daniluk, Y. Liu Intracellular activation of trypsinogen in transgenic mice induces acute but not chronic pancreatitis Gut 60 2011 1379 1388
9. B. Ji, L. Tsou, H. Wang Ras activity levels control the development of pancreatic diseases Gastroenterology 137 2009 1072 1082
10. J. Daniluk, Y. Liu, D. Deng An NF-κB pathway-mediated positive feedback loop amplifies Ras activity to pathological levels in mice J Clin Invest 122 2012 1519 1528
11. D.C. Whitcomb, M.C. Gorry, R.A. Preston Hereditary pancreatitis is caused by a mutation in the cationic trypsinogen gene Nature Genetics 14 1996 141 145
12. A. Szabo, M. Sahin-Toth Increased activation of hereditary pancreatitis-associated human cationic trypsinogen mutants in the presence of chymotrypsin C J Biol Chem 287 2012 20701 20710
13. J. Zhou, M. Sahin-Toth Chymotrypsin C mutations in chronic pancreatitis J Gastroenterol Hepatol 26 2011 1238 1246
14. C.Y. Ooi, R. Dorfman, M. Cipolli Type of CFTR mutation determines risk of pancreatitis in patients with cystic fibrosis Gastroenterology 140 2011 153 161
15. G.R. Boocock, J.A. Morrison, M. Popovic Mutations in SBDS are associated with Shwachman-Diamond syndrome Nat Genet 33 2003 97 101
16. M.E. Tourlakis, J. Zhong Deficiency of SBDS in the mouse pancreas leads to features of Shwachman-Diamond syndrome, with loss of zymogen granules Gastroenterology 143 2012 481 492
17. T. Wartmann, J. Mayerle, T. Kähne Cathepsin L inactivates human trypsinogen, whereas cathepsin L-deletion reduces the severity of pancreatitis in mice Gastroenterology 138 2010 726 737
18. P.J. Pasricha Unraveling the mystery of pain in chronic pancreatitis Nat Rev Gastroenterol Hepatol 9 2012 140 151
19. R.A. Liddle, J.D. Nathan Neurogenic inflammation and pancreatitis Pancreatology 4 2004 551 559
20. I.E. Demir, H. Friess, G.O. Ceyhan Nerve-cancer interactions in the stromal biology of pancreatic cancer Front Physiol 3 2012 97