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Volumn 108, Issue 11, 2012, Pages 2054-2065

Immune status is more affected by age than by carotenoid depletion-repletion in healthy human subjects

Author keywords

Carotene; Chemotaxis; Delayed type hypersensitivity; Dietary depletion and repletion; Immunoglobulins; Interleukins; Phagocytosis

Indexed keywords

BETA CAROTENE; CAROTENOID; CD45RA ANTIGEN; CD45RO ANTIGEN; IMMUNOGLOBULIN A; IMMUNOGLOBULIN G; IMMUNOGLOBULIN M; INTERLEUKIN 2; LYCOPENE; PHYTOHEMAGGLUTININ; XANTHOPHYLL;

EID: 84871270647     PISSN: 00071145     EISSN: 14752662     Source Type: Journal    
DOI: 10.1017/S0007114512000177     Document Type: Article
Times cited : (17)

References (44)
  • 1
    • 0034773365 scopus 로고    scopus 로고
    • Dietary carotenoids and human immune function
    • Hughes DA (2001) Dietary carotenoids and human immune function. Nutrition 17, 823-827.
    • (2001) Nutrition , vol.17 , pp. 823-827
    • Hughes, D.A.1
  • 2
    • 0346726169 scopus 로고    scopus 로고
    • Carotenoid action on the immune response
    • Chew BP & Park JS (2004) Carotenoid action on the immune response. J Nutr 134, 257S-261S.
    • (2004) J Nutr , vol.134
    • Chew, B.P.1    Park, J.S.2
  • 3
    • 0029945201 scopus 로고    scopus 로고
    • Beta-carotene, carotenoids, and disease prevention in humans
    • Mayne ST (1996) Beta-carotene, carotenoids, and disease prevention in humans. FASEB J 10, 690-701.
    • (1996) FASEB J , vol.10 , pp. 690-701
    • Mayne, S.T.1
  • 4
    • 0347986902 scopus 로고    scopus 로고
    • Carotenoids in health and disease: Recent scientific evaluations, research recommendations and the consumer
    • Cooper DA (2004) Carotenoids in health and disease: recent scientific evaluations, research recommendations and the consumer. J Nutr 134, 221S-224S.
    • (2004) J Nutr , vol.134
    • Cooper, D.A.1
  • 5
    • 0035436859 scopus 로고    scopus 로고
    • Vitamin A, vitamin e and carotenoid status and metabolism during ageing: Functional and nutritional consequences (VITAGE PROJECT)
    • Rock E, Winklhofer-Roob BM, Ribalta J, et al. (2001) Vitamin A, vitamin E and carotenoid status and metabolism during ageing: functional and nutritional consequences (VITAGE PROJECT). Nutr Metab Cardiovasc Dis 11, 4 Suppl., 70-73.
    • (2001) Nutr Metab Cardiovasc Dis , vol.11 , Issue.4 SUPPL. , pp. 70-73
    • Rock, E.1    Winklhofer-Roob, B.M.2    Ribalta, J.3
  • 6
    • 0028172118 scopus 로고
    • Effect of low beta-carotene diet on the immune functions of adult women
    • Daudu PA, Kelley DS, Taylor PC, et al. (1994) Effect of low beta-carotene diet on the immune functions of adult women. Am J Clin Nutr 60, 969-972.
    • (1994) Am J Clin Nutr , vol.60 , pp. 969-972
    • Daudu, P.A.1    Kelley, D.S.2    Taylor, P.C.3
  • 7
    • 1342333678 scopus 로고    scopus 로고
    • Supplementation of a low-carotenoid diet with tomato or carrot juice modulates immune functions in healthy men
    • Watzl B, Bub A, Briviba K, et al. (2003) Supplementation of a low-carotenoid diet with tomato or carrot juice modulates immune functions in healthy men. Ann Nutr Metab 47, 255-261.
    • (2003) Ann Nutr Metab , vol.47 , pp. 255-261
    • Watzl, B.1    Bub, A.2    Briviba, K.3
  • 8
    • 0029670923 scopus 로고    scopus 로고
    • Beta-carotene supplementation enhances lymphocyte proliferation with mitogens in human peripheral blood lymphocytes
    • Moriguchi S, Okishima N, Sumida S, et al. (1996) Beta-carotene supplementation enhances lymphocyte proliferation with mitogens in human peripheral blood lymphocytes. Nutr Res 16, 211-218.
    • (1996) Nutr Res , vol.16 , pp. 211-218
    • Moriguchi, S.1    Okishima, N.2    Sumida, S.3
  • 9
    • 0030891323 scopus 로고    scopus 로고
    • The effect of beta-carotene supplementation on the immune function of blood monocytes from healthy male nonsmokers
    • Hughes DA, Wright AJ, Finglas PM, et al. (1997) The effect of beta-carotene supplementation on the immune function of blood monocytes from healthy male nonsmokers. J Lab Clin Med 129, 309-317.
    • (1997) J Lab Clin Med , vol.129 , pp. 309-317
    • Hughes, D.A.1    Wright, A.J.2    Finglas, P.M.3
  • 10
    • 0021855256 scopus 로고
    • Oral beta-carotene can increase the number of OKT4 cells in human blood
    • Alexander M, Newmark H & Miller RG (1985) Oral beta-carotene can increase the number of OKT4 cells in human blood. Immunol Lett 9, 221-224.
    • (1985) Immunol Lett , vol.9 , pp. 221-224
    • Alexander, M.1    Newmark, H.2    Miller, R.G.3
  • 11
    • 0026085868 scopus 로고
    • Effect of beta-carotene on lymphocyte subpopulations in elderly humans: Evidence for a dose-response relationship
    • Watson RR, Prabhala RH, Plezia PM, et al. (1991) Effect of beta-carotene on lymphocyte subpopulations in elderly humans: evidence for a dose-response relationship. Am J Clin Nutr 53, 90-94.
    • (1991) Am J Clin Nutr , vol.53 , pp. 90-94
    • Watson, R.R.1    Prabhala, R.H.2    Plezia, P.M.3
  • 12
    • 0025908398 scopus 로고
    • Beta-carotene's effects on serum lipoproteins and immunologic indices in humans
    • Ringer TV, De Loof MJ, Winterrowd GE, et al. (1991) Beta-carotene's effects on serum lipoproteins and immunologic indices in humans. Am J Clin Nutr 53, 688-694.
    • (1991) Am J Clin Nutr , vol.53 , pp. 688-694
    • Ringer, T.V.1    De Loof, M.J.2    Winterrowd, G.E.3
  • 13
    • 0034067067 scopus 로고    scopus 로고
    • Effect of beta-carotene supplementation and lactation on caroten-oid metabolism and mitogenic T lymphocyte proliferation
    • Gossage C, Deyhim M, Moser-Veillon PB, et al. (2000) Effect of beta-carotene supplementation and lactation on caroten-oid metabolism and mitogenic T lymphocyte proliferation. Am J Clin Nutr 71, 950-955.
    • (2000) Am J Clin Nutr , vol.71 , pp. 950-955
    • Gossage, C.1    Deyhim, M.2    Moser-Veillon, P.B.3
  • 14
    • 33845510496 scopus 로고    scopus 로고
    • Effect of a mixture of micronutrients, but not of bovine colostrum concentrate, on immune function parameters in healthy volunteers: A randomized placebo-controlled study
    • Wolvers DA, van Herpen-Broekmans WM, Logman MH, et al. (2006) Effect of a mixture of micronutrients, but not of bovine colostrum concentrate, on immune function parameters in healthy volunteers: a randomized placebo-controlled study. Nutr J 5, 28.
    • (2006) Nutr J , vol.5 , pp. 28
    • Wolvers, D.A.1    Van Herpen-Broekmans, W.M.2    Logman, M.H.3
  • 15
    • 67649435597 scopus 로고    scopus 로고
    • Bioavailability and nutritional effects of carotenoids from organically and conventionally produced carrots in healthy men
    • Stracke BA, Rüfer CE, Bub A, et al. (2009) Bioavailability and nutritional effects of carotenoids from organically and conventionally produced carrots in healthy men. Br J Nutr 101, 1664-1672.
    • (2009) Br J Nutr , vol.101 , pp. 1664-1672
    • Stracke, B.A.1    Rüfer, C.E.2    Bub, A.3
  • 16
    • 0030823264 scopus 로고    scopus 로고
    • Short-and long-term beta-carotene supplementation do not influence T cell-mediated immunity in healthy elderly persons
    • Santos MS, Leka LS, Ribaya-Mercado JD, et al. (1997) Short-and long-term beta-carotene supplementation do not influence T cell-mediated immunity in healthy elderly persons. Am J Clin Nutr 66, 917-924.
    • (1997) Am J Clin Nutr , vol.66 , pp. 917-924
    • Santos, M.S.1    Leka, L.S.2    Ribaya-Mercado, J.D.3
  • 17
    • 0029964813 scopus 로고    scopus 로고
    • Natural killer cell activity in elderly men is enhanced by beta-carotene supplementation
    • Santos MS, Meydani SN, Leka L, et al. (1996) Natural killer cell activity in elderly men is enhanced by beta-carotene supplementation. Am J Clin Nutr 64, 772-777.
    • (1996) Am J Clin Nutr , vol.64 , pp. 772-777
    • Santos, M.S.1    Meydani, S.N.2    Leka, L.3
  • 18
    • 0031780613 scopus 로고    scopus 로고
    • Beta-carotene-induced enhancement of natural killer cell activity in elderly men: An investigation of the role of cytokines
    • Santos MS, Gaziano JM, Leka LS, et al. (1998) Beta-carotene-induced enhancement of natural killer cell activity in elderly men: an investigation of the role of cytokines. Am J Clin Nutr 68, 164-170.
    • (1998) Am J Clin Nutr , vol.68 , pp. 164-170
    • Santos, M.S.1    Gaziano, J.M.2    Leka, L.S.3
  • 19
    • 0033506266 scopus 로고    scopus 로고
    • Beta-carotene and selenium supplementation enhances immune response in aged humans
    • Wood SM, Beckham C, Yosioka A, et al. (2000) Beta-carotene and selenium supplementation enhances immune response in aged humans. Integr Med 2, 85-92.
    • (2000) Integr Med , vol.2 , pp. 85-92
    • Wood, S.M.1    Beckham, C.2    Yosioka, A.3
  • 20
    • 0034748745 scopus 로고    scopus 로고
    • Specific and nonspecific immune responses to fasting and refeeding differ in healthy young adult and elderly persons
    • Walrand S, Moreau K, Caldefie F, et al. (2001) Specific and nonspecific immune responses to fasting and refeeding differ in healthy young adult and elderly persons. Am J Clin Nutr 74, 670-678.
    • (2001) Am J Clin Nutr , vol.74 , pp. 670-678
    • Walrand, S.1    Moreau, K.2    Caldefie, F.3
  • 21
    • 0032710872 scopus 로고    scopus 로고
    • Modulation of human T-lymphocyte functions by the consumption of carotenoid-rich vegetables
    • Watzl B, Bub A, Brandstetter BR, et al. (1999) Modulation of human T-lymphocyte functions by the consumption of carotenoid-rich vegetables. Br J Nutr 82, 383-389.
    • (1999) Br J Nutr , vol.82 , pp. 383-389
    • Watzl, B.1    Bub, A.2    Brandstetter, B.R.3
  • 22
    • 0033817671 scopus 로고    scopus 로고
    • Effects of lycopene and lutein supplementation on the expression of functionally associated surface molecules on blood monocytes from healthy male nonsmokers
    • Hughes DA, Wright AJ, Finglas PM, et al. (2000) Effects of lycopene and lutein supplementation on the expression of functionally associated surface molecules on blood monocytes from healthy male nonsmokers. J Infect Dis 182, Suppl. 1, S11-S15.
    • (2000) J Infect Dis , vol.182 , Issue.SUPPL. 1
    • Hughes, D.A.1    Wright, A.J.2    Finglas, P.M.3
  • 23
    • 0034882534 scopus 로고    scopus 로고
    • Low-dose supplementation with lycopene or beta-carotene does not enhance cell-mediated immunity in healthy free-living elderly humans
    • Corridan BM, O'Donoghue M, Hughes DA, et al. (2001) Low-dose supplementation with lycopene or beta-carotene does not enhance cell-mediated immunity in healthy free-living elderly humans. Eur J Clin Nutr 55, 627-635.
    • (2001) Eur J Clin Nutr , vol.55 , pp. 627-635
    • Corridan, B.M.1    O'Donoghue, M.2    Hughes, D.A.3
  • 25
    • 0021739814 scopus 로고
    • Admission criteria for immunogerontological studies in man: The SENIEUR protocol
    • Ligthart GJ, Corberand JX, Fournier C, et al. (1984) Admission criteria for immunogerontological studies in man: the SENIEUR protocol. Mech Ageing Dev 28, 47-55.
    • (1984) Mech Ageing Dev , vol.28 , pp. 47-55
    • Ligthart, G.J.1    Corberand, J.X.2    Fournier, C.3
  • 26
    • 18344389163 scopus 로고    scopus 로고
    • A European multicentre, placebo-controlled supplementation study with alpha-tocopherol, carotene-rich palm oil, lutein or lycopene: Analysis of serum responses
    • Olmedilla B, Granado F, Southon S, et al. (2002) A European multicentre, placebo-controlled supplementation study with alpha-tocopherol, carotene-rich palm oil, lutein or lycopene: analysis of serum responses. Clin Sci (Lond) 102, 447-456.
    • (2002) Clin Sci (Lond) , vol.102 , pp. 447-456
    • Olmedilla, B.1    Granado, F.2    Southon, S.3
  • 27
    • 0035946030 scopus 로고    scopus 로고
    • Simple method for clinical determination of 13 carotenoids in human plasma using an isocatric high-performance liquid chromatographic method
    • Lyan B, Azais-Braesco V, Cardinault N, et al. (2001) Simple method for clinical determination of 13 carotenoids in human plasma using an isocatric high-performance liquid chromatographic method. J Chromatogr B Biomed Sci Appl 751, 297-303.
    • (2001) J Chromatogr B Biomed Sci Appl , vol.751 , pp. 297-303
    • Lyan, B.1    Azais-Braesco, V.2    Cardinault, N.3
  • 28
    • 0037402817 scopus 로고    scopus 로고
    • Flow cytome-try study of polymorphonuclear neutrophil oxidative burst: A comparison of three fluorescent probes
    • Walrand S, Valeix S, Rodriguez C, et al. (2003) Flow cytome-try study of polymorphonuclear neutrophil oxidative burst: a comparison of three fluorescent probes. Clin Chim Acta 331, 103-110.
    • (2003) Clin Chim Acta , vol.331 , pp. 103-110
    • Walrand, S.1    Valeix, S.2    Rodriguez, C.3
  • 29
    • 0035076118 scopus 로고    scopus 로고
    • Serum concentrations of carotenoids and vitamins A, e and C in control subjects from five European countries
    • Olmedilla B, Granado F, Southon S, et al. (2001) Serum concentrations of carotenoids and vitamins A, E and C in control subjects from five European countries. Br J Nutr 80, 227-238.
    • (2001) Br J Nutr , vol.80 , pp. 227-238
    • Olmedilla, B.1    Granado, F.2    Southon, S.3
  • 30
    • 1042265444 scopus 로고    scopus 로고
    • Effects of aging on immune function
    • Burns EA (2004) Effects of aging on immune function. J Nutr Health Aging 8, 9-18.
    • (2004) J Nutr Health Aging , vol.8 , pp. 9-18
    • Burns, E.A.1
  • 31
    • 0034631866 scopus 로고    scopus 로고
    • Immune function and vaccine responses in healthy advanced elderly patients
    • Carson PJ, Nichol KL, O'Brien J, et al. (2000) Immune function and vaccine responses in healthy advanced elderly patients. Arch Intern Med 160, 2017-2024.
    • (2000) Arch Intern Med , vol.160 , pp. 2017-2024
    • Carson, P.J.1    Nichol, K.L.2    O'Brien, J.3
  • 32
    • 0026480855 scopus 로고
    • Changes in circulating B cells and immunoglobulin classes and subclasses in a healthy aged population
    • Paganelli R, Quinti I, Fagiolo U, et al. (1992) Changes in circulating B cells and immunoglobulin classes and subclasses in a healthy aged population. Clin Exp Immunol 90, 351-354.
    • (1992) Clin Exp Immunol , vol.90 , pp. 351-354
    • Paganelli, R.1    Quinti, I.2    Fagiolo, U.3
  • 33
    • 0032716683 scopus 로고    scopus 로고
    • The immune system in the elderly: I. Specific humoral immunity
    • Ginaldi L, De Martinis M, D'Ostilio A, et al. (1999) The immune system in the elderly: I. Specific humoral immunity. Immunol Res 20, 101-108.
    • (1999) Immunol Res , vol.20 , pp. 101-108
    • Ginaldi, L.1    De Martinis, M.2    D'Ostilio, A.3
  • 34
    • 0028122578 scopus 로고
    • Cell mediated immunity changes in ageing, relative importance of cell subpopulation switches and of nutritional factors
    • Lesourd BM & Meaume S (1994) Cell mediated immunity changes in ageing, relative importance of cell subpopulation switches and of nutritional factors. Immunol Lett 40, 235-242.
    • (1994) Immunol Lett , vol.40 , pp. 235-242
    • Lesourd, B.M.1    Meaume, S.2
  • 35
    • 77955669620 scopus 로고    scopus 로고
    • Neutro-phils are immune cells preferentially targeted by retinoic acid in elderly subjects
    • Minet-Quinard R, Farges MC, Thivat E, et al. (2010) Neutro-phils are immune cells preferentially targeted by retinoic acid in elderly subjects. Immun Ageing 7, 10.
    • (2010) Immun Ageing , vol.7 , pp. 10
    • Minet-Quinard, R.1    Farges, M.C.2    Thivat, E.3
  • 36
    • 0032143491 scopus 로고    scopus 로고
    • Nutritional influences on immune response in healthy aged persons
    • Mazari L & Lesourd BM (1998) Nutritional influences on immune response in healthy aged persons. Mech Ageing Dev 104, 25-40.
    • (1998) Mech Ageing Dev , vol.104 , pp. 25-40
    • Mazari, L.1    Lesourd, B.M.2
  • 37
    • 0026200349 scopus 로고
    • Beta-carotene and the immune response
    • Bendich A (1991) Beta-carotene and the immune response. Proc Nutr Soc 50, 263-274.
    • (1991) Proc Nutr Soc , vol.50 , pp. 263-274
    • Bendich, A.1
  • 38
    • 0035906336 scopus 로고    scopus 로고
    • Carotenoids and genomic stability
    • Collins AR (2001) Carotenoids and genomic stability. Mutat Res 475, 21-28.
    • (2001) Mutat Res , vol.475 , pp. 21-28
    • Collins, A.R.1
  • 39
    • 0345874648 scopus 로고    scopus 로고
    • Evidence that dietary supplementation with carotenoids and carotenoid-rich foods modulates the DNA damage: Repair balance in human lymphocytes
    • Astley SB, Elliott RM, Archer DB, et al. (2004) Evidence that dietary supplementation with carotenoids and carotenoid-rich foods modulates the DNA damage: repair balance in human lymphocytes. Br J Nutr 91, 63-72.
    • (2004) Br J Nutr , vol.91 , pp. 63-72
    • Astley, S.B.1    Elliott, R.M.2    Archer, D.B.3
  • 40
    • 26044440174 scopus 로고    scopus 로고
    • Markers to measure immunomodulation in human nutrition intervention studies
    • Albers R, Antoine JM, Bourdet-Sicard R, et al. (2005) Markers to measure immunomodulation in human nutrition intervention studies. Br J Nutr 94, 452-481.
    • (2005) Br J Nutr , vol.94 , pp. 452-481
    • Albers, R.1    Antoine, J.M.2    Bourdet-Sicard, R.3
  • 41
    • 0033844994 scopus 로고    scopus 로고
    • Vitamin A, vitamin e and carotenoid status and metabolism during ageing: Functional and nutritional consequences
    • Azais-Braesco V, Winklhofer-Roob B, Ribalta J, et al. (2000) Vitamin A, vitamin E and carotenoid status and metabolism during ageing: functional and nutritional consequences. Endocr Regul 34, 97-98.
    • (2000) Endocr Regul , vol.34 , pp. 97-98
    • Azais-Braesco, V.1    Winklhofer-Roob, B.2    Ribalta, J.3
  • 42
    • 0025201385 scopus 로고
    • Effects of b-carotene repletion on b-carotene absorption, lipid peroxidation, and neutrophil superoxide formation in young men
    • Mobarhan S, Bowen P, Andersen B, et al. (1990) Effects of b-carotene repletion on b-carotene absorption, lipid peroxidation, and neutrophil superoxide formation in young men. Nutr Cancer 14, 195-206.
    • (1990) Nutr Cancer , vol.14 , pp. 195-206
    • Mobarhan, S.1    Bowen, P.2    Andersen, B.3
  • 43
    • 0027996609 scopus 로고
    • Effects of a carotene-deficient diet on measures of oxidative susceptibility and superoxide dismutase activity in adult women
    • Dixon ZR, Burri BJ, Clifford A, et al. (1994) Effects of a carotene-deficient diet on measures of oxidative susceptibility and superoxide dismutase activity in adult women. Free Radic Biol Med 17, 537-544.
    • (1994) Free Radic Biol Med , vol.17 , pp. 537-544
    • Dixon, Z.R.1    Burri, B.J.2    Clifford, A.3
  • 44
    • 0030858674 scopus 로고    scopus 로고
    • Effect of two year supplementation with low doses of antioxidant vitamins and/or minerals in elderly subjects on levels of nutrients and antioxidant defense parameters
    • Girodon F, Blache D, Monget AL, et al. (1997) Effect of two year supplementation with low doses of antioxidant vitamins and/or minerals in elderly subjects on levels of nutrients and antioxidant defense parameters. J Am Coll Nutr 16, 357-365.
    • (1997) J Am Coll Nutr , vol.16 , pp. 357-365
    • Girodon, F.1    Blache, D.2    Monget, A.L.3


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