Bi-directional relationship between pregnancy and periodontal disease

Periodontology 2000

Volumn 61, Issue 1, 2013, Pages 160-176

  Armitage, Gary C ^a  

^a NONE

Author keywords

[No Author keywords available]

Indexed keywords

ADAPTIVE IMMUNITY; ARTICLE; DISEASE PREDISPOSITION; FEMALE; HUMAN; IMMUNOLOGY; INNATE IMMUNITY; MICROBIOLOGY; PERIODONTAL DISEASE; PERIODONTIUM; PREGNANCY; PREGNANCY COMPLICATION; PREGNANCY OUTCOME;

ADAPTIVE IMMUNITY; DISEASE SUSCEPTIBILITY; FEMALE; HUMANS; IMMUNITY, INNATE; PERIODONTAL DISEASES; PERIODONTIUM; PREGNANCY; PREGNANCY COMPLICATIONS; PREGNANCY OUTCOME;

EID: 84871245019     PISSN: 09066713     EISSN: 16000757     Source Type: Journal    
DOI: 10.1111/j.1600-0757.2011.00396.x     Document Type: Article

References (223)

1. Agueda A, Ramón JM, Manau C, Guerrero A, Echeverría JJ. Periodontal disease as a risk factor for adverse pregnancy outcomes: a prospective cohort study. J Clin Periodontol 2008: 35: 16-22.
2. Ainamo J, Barmes D, Beagrie G, Cutress T, Martin J, Sardo-Infirri J. Development of the World Health Organization (WHO) community periodontal index of treatment needs (CPITN). Int Dent J 1982: 32: 281-291.
3. Alves RT, Ribeiro RA. Relationship between maternal periodontal disease and birth of preterm low weight babies. Braz Oral Res 2006: 20: 318-323.
4. Amino N, Tada H, Hidaka Y. Postpartum autoimmune thyroid syndrome: a model of aggravation of autoimmune disease. Thyroid 1999: 9: 705-713.
5. Annapureddy SR, Masterson SW, David HG, Greig JR. Post partum osteomyelitis due to Cryptococcus neoformans. Scand J Infect Dis 2007: 39: 354-356.
6. Apatzidou DA, Kinane DF. Quadrant root planing versus same-day full-mouth root planing. I. Clinical findings. J Clin Periodontol 2004: 31: 132-140.
7. Arafat AH. Periodontal status during pregnancy. J Periodontol 1974: 45: 641-643.
8. Armitage GC. Effect of periodontal therapy on general health - is there a missing component in the design of these clinical trials? J Clin Periodontol 2008: 35: 1011-1012.
9. Barak S, Oettinger-Barak O, Machtei EE, Sprecher H, Ohel G. Evidence of periopathogenic microorganisms in placentas of women with preeclampsia. J Periodontol 2007: 78: 670-676.
10. Bassani DG, Olinto MTA, Kreiger N. Periodontal disease and perinatal outcomes: a case-control study. J Clin Periodontol 2007: 34: 31-39.
11. Bearfield C, Davenport ES, Sivapathasundaram V, Allaker RP. Possible association between amniotic fluid micro-organism infection and microflora in the mouth. Br J Obstet Gynaecol 2002: 109: 527-533.
12. Beck JD, Offenbacher S. Relationships among clinical measures of periodontal disease and their associations with systemic markers. Ann Periodontol 2002: 7: 79-89.
13. Beer AE, Billingham RE. Immunobiology of mammalian reproduction. Adv Immunol 1971: 14: 1-84.
14. Belcher C, Doherty M, Crouch SPM. Synovial fluid neutrophil function in RA: the effect of pregnancy associated proteins. Ann Rheum Dis 2002: 61: 379-380.
15. Benhaim RD, Davies TF. Increased risk of Graves' disease after pregnancy. Thyroid 2005: 15: 1287-1290.
16. Bobetsis YA, Barros SP, Lin DM, Weidman JR, Dolinoy DC, Jirtle RL, Boggess KA, Beck JD, Offenbacher S. Bacterial infection promotes DNA methylation. J Dent Res 2007: 86: 169-174.
17. Boggess KA, Lieff S, Murtha AP, Moss K, Beck J, Offenbacher S. Maternal periodontal disease is associated with an increased risk of preeclampsia. Obstet Gynecol 2003: 101: 227-231.
18. Boggess KA, Moss K, Madianos P, Murtha AP, Beck J, Offenbacher S. Fetal immune response to oral pathogens and risk of preterm birth. Am J Obstet Gynecol 2005: 193: 1121-1126.
19. Boggess KA, Beck JD, Murtha AP, Moss K, Offenbacher S. Maternal periodontal disease in early pregnancy and risk for a small-for-gestational-age infant. Am J Obstet Gynecol 2006: 194: 1316-1322.
20. Boggess KA, for the Society for Maternal-Fetal Medicine Publications Committee. Maternal oral health in pregnancy. Obstet Gynecol 2008: 111: 976-986.
21. Boggess KA. Editorial. Treatment of localized periodontal disease in pregnancy does not reduce the occurrence of preterm birth: results from the Periodontal Infections and Prematurity Study (PIPS). Am J Obstet Gynecol 2010: 202: 101-102.
22. Bond TE. Pregnancy. In: A practical treatise on dental medicine, 2nd edn. Philadelphia, PA: Lindsay & Blakiston, 1852: 163-164.
23. Bosnjak A, Relja T, Vucicevic-Boras V, Plasaj H, Plancak D. Pre-term delivery and periodontal disease: a case-control study from Croatia. J Clin Periodontol 2006: 33: 710-716.
24. Buduneli N, Baylas H, Buduneli E, Tükoglu O, Dahlen G. Evaluation of the relationship between smoking during pregnancy and subgingival microbiota. J Clin Periodontol 2005: 32: 68-74.
25. Buduneli N, Baylas H, Buduneli E, Türkoglu O, Köse T, Dahlen G. Periodontal infections and pre-term low birth weight: a case-control study. J Clin Periodontol 2005: 32: 174-181.
26. Canakci V, Canakci CF, Canakci H, Canakci E, Cicek Y, Ingec M, Ozgoz M, Demir T, Dilsiz A, Yagiz H. Periodontal disease as a risk factor for pre-eclampsia: a case-control study. Aust NZ J Obstet Gynaecol 2004: 44: 568-573.
27. Canakci V, Canacki CF, Yildirim A, Ingec M, Eltas A, Erturk A. Periodontal disease increases the risk of severe pre-eclampsia among pregnant women. J Clin Periodontol 2007: 34: 639-645.
28. Canacki V, Yildirim A, Canacki CF, Eltas A, Cicek Y, Canacki H. Total antioxidant capacity and antioxidant enzymes in serum, saliva, and gingival crevicular fluid of preeclamptic women with and without periodontal disease. J Periodontol 2007: 78: 1602-1611.
29. Castaldi JL, Berin MS, Giménez F, Lede R. Periodontal disease: is it a risk factor for premature labor, low birth weight or preeclampsia? Rev Panam Salud Publica 2006: 19: 253-258 [Article in Spanish].
30. Chaouat G. Innately moving away from the Th1/Th2 paradigm in pregnancy. Clin Exp Immunol 2003: 131: 393-395.
31. Chen JD, Chung JL, Kao JH, Chen DS. Post-partum acute exacerbation of chronic hepatitis in a hepatitisC carrier mother. J Gastroenterol Hepatol 2001: 16: 705-708.
32. Cheng VCC, Woo PCY, Lau SKP, Cheung CHY, Yung RWH, Yam LYC, Yuen KY. Peripartum tuberculosis as a form of immunorestitution disease. Eur J Clin Microbiol Infect Dis 2003: 22: 313-317.
33. Christensen K, Gaist D, Jeune B, Vaupel JW. A tooth per child? Lancet 1998: 352: 204.
34. Cohen DW, Friedman L, Shapiro J, Kyle GC. A longitudinal investigation of the periodontal changes during pregnancy. J Periodontol 1969: 40: 563-570.
35. Cohen DW, Shapiro J, Friedman L, Kyle GC, Franklin S. A longitudinal investigation of the periodontal changes during pregnancy and fifteen months post-partum: II. J Periodontol 1971: 42: 653-657.
36. Conde-Agudelo A, Villar J, Lindheimer M. Maternal infection and risk of preeclampsia: systematic review and metaanalysis. Am J Obstet Gynecol 2008: 198: 7-22.
37. Confavreux C, Hutchinson M, Hours MM, Cortinovis-Tourniaire P, Moreau T, for the Pregnancy in Multiple Sclerosis Group. Rate of pregnancy-related relapse in multiple sclerosis. N Engl J Med 1998: 339: 285-291.
38. Contreras A, Herrera JA, Soto JE, Arce RM, Jaramillo A, Botero JE. Periodontitis is associated with preeclampsia in pregnant women. J Periodontol 2006: 77: 182-188.
39. Cota LOM, Guimarães AN, Costa JE, Lorentz TCM, Costa FO. Association between maternal periodontitis and increased risk of preeclampsia. J Periodontol 2006: 77: 2063-2069.
40. Crocker I, Lawson N, Daniels I, Baker P, Fletcher J. Significance of fatty acids in pregnancy-induced immunosuppression. Clin Diagn Lab Immunol 1999: 6: 587-593.
41. Crocker I, Baker P, Fletcher J. Neutrophil function in pregnancy and rheumatoid arthritis. Ann Rheum Dis 2000: 59: 555-564.
42. Crouch SP, Crocker IP, Fletcher J. The effect of pregnancy on polymorphonuclear leukocyte function. J Immunol 1995: 155: 5436-5443.
43. Cruz SS, Costa MCN, Filho ISG, Vianna MIP, Santos CT. Maternal periodontal disease as a factor associated with low birth weight. Rev Saúde Pública 2005: 39: 782-787. [Article in Portuguese].
44. Dasanayake AP. Poor periodontal health of the pregnant woman as a risk factor for low birth weight. Ann Periodontol 1998: 3: 206-212.
45. Dasanayake AP, Boyd D, Madianos PN, Offenbacher S, Hills E. The association between Porphyromonas gingivalis-specific maternal serum IgG and low birth weight. J Periodontol 2001: 72: 1491-1497.
46. Dasanayake AP, Chhun N, Tanner ACR, Craig RG, Lee MJ, Moore AF, Norman RG. Periodontal pathogens and gestational diabetes. J Dent Res 2008: 87: 328-333.
47. Da Silva JAP, Spector TD. The role of pregnancy in the course and aetiology of rheumatoid arthritis. Clin Rheumatol 1992: 11: 189-194.
48. Davenport ES, Williams CECS, Sterne JAC, Sivapathasundram V, Fearne JM, Curtis MA. The East London study of maternal chronic periodontal disease and preterm low birth weight infants: study design and prevalence data. Ann Periodontol 1998: 3: 213-221.
49. Davenport ES, Williams CECS, Sterne JAC, Murad S, Sivapathasundram V, Curtis MA. Maternal periodontal disease and preterm low birthweight: case-control study. J Dent Res 2002: 81: 313-318.
50. Demir Y, Demir S, Aktepe F. Cutaneous lobular capillary hemangioma induced by pregnancy. J Cutan Pathol 2004: 31: 77-80.
51. Dorn BR, Dunn WA Jr, Progulske-Fox A. Bacterial interactions with the autophagic pathway. Cell Microbiol 2002: 4: 1-10.
52. Dörtbudak O, Eberhardt R, Ulm M, Persson GR. Periodontitis, a marker of risk in pregnancy for preterm birth. J Clin Periodontol 2005: 32: 45-52.
53. Duncan ME, Melsom R, Pearson JM, Ridley DS. The association of pregnancy and leprosy. I. New cases, relapse of cured patients and deterioration in patients on treatment during pregnancy and lactation - results of a prospective study of 154 pregnancies in 147 Ethiopian women. Lepr Rev 1981: 52: 245-262.
54. 2+signaling, and gene expression in Tlymphocytes. J Exp Med 1998: 188: 1593-1602.
55. El-Ashiry GM, El-Kafrawy A-H, Nasr MF, Younis N. Gingival condition of Egyptian pregnant women. J Periodontol 1971: 42: 271-275.
56. El-Maallem H, Fletcher J. Impaired neutrophil function and myeloperoxidase deficiency in pregnancy. Br J Haematol 1980: 44: 375-381.
57. Epivatianos A, Antoniades D, Zaraboukas T, Zairi E, Poulopoulos A, Kiziridou A, Iordanidis S. Pyogenic granuloma of the oral cavity: comparative study of its clinicopathological and immunohistochemical features. Pathol Int 2005: 55: 391-397.
58. Erb A, Brzezinsky A. Gingivitis in pregnant Israeli women. J Periodontol 1963: 34: 447-450.
59. Farrell S, Ide M, Wilson RF. The relationship between maternal periodontitis, adverse pregnancy outcome and miscarriage in never smokers. J Clin Periodontol 2006: 33: 115-120.
60. Ferguson JE, Hansen WF, Novak KF, Novak MJ. Should we treat periodontal disease during gestation to improve pregnancy outcomes? Clin Obstet Gynecol 2007: 50: 454-467.
61. Fievet N, Tami G, Maubert B, Moussa M, Shaw IK, Cot M, Holder AA, Chaouat G, Deloron P. Cellular immune response to Plasmodium falciparum after pregnancy is related to previous placental infection and parity. Malar J 2002: 1: 16.
62. Gazolla CM, Ribeiro A, Moysés MR, Oliveira LAM, Pereira LJ, Sallum AW. Evaluation of the incidence of preterm low birth weight in patients undergoing periodontal therapy. J Periodontol 2007: 78: 842-848.
63. Goepfert AR, Jeffcoat MK, Andrews WW, Faye-Petersen O, Cliver SP, Goldenberg RL, Hauth JC. Periodontal disease and upper genital tract inflammation in early spontaneous preterm birth. Obstet Gynecol 2004: 104: 777-783.
64. Goldenberg RL, Culhane JF. Prepregnancy health status and the risk of preterm delivery. Arch Pediatr Adolesc Med 2005: 159: 89-90.
65. Goldenberg RL, Culhane JF. Preterm birth and periodontal disease. N Engl J Med 2006: 355: 1925-1927.
66. Goldenberg RL, Culhane JF, Iams JD, Romero R. Epidemiology and causes of preterm birth. Lancet 2008: 371: 75-84.
67. Gomes-Filho IS, Cruz SS, Rezende EJC, dos Santos CAST, Soldade KR, Magalhães MA, de Azavedo ACO, Trindade SC, Vianna MIP, de S. Passos JCerqueira EMM. Exposure measurement in the association between periodontal disease and prematurity/low birth weight. J Clin Periodontol 2007: 34: 957-963.
68. Gridly MS. Gingival condition in pregnant women. A report based on the examination of the gingivae of 1, 002 pregnant women. Oral Surg Oral Med Oral Pathol 1954: 7: 641-646.
69. Gürsoy M, Pajukanta R, Sorsa T, Könönen E. Clinical changes in periodontium during pregnancy and post-partum. J Clin Periodontol 2008: 35: 576-583.
70. Han YW, Ikegami A, Bissada NF, Herbst M, Redline RW, Ashmead GG. Transmission of uncultivated Bergeyella strain from the oral cavity to amniotic fluid in a case of preterm birth. J Clin Microbiol 2006: 44: 1475-1483.
71. Hasegawa K, Furuichi Y, Shimotsu A, Nakamura M, Yoshinaga M, Kamitoma M, Hatae M, Maruyama I, Izumi Y. Associations between systemic status, periodontal status, serum cytokine levels, and delivery outcomes in pregnant women with a diagnosis of threatened premature labor. J Periodontol 2003: 74: 1764-1770.
72. Herrera JA, Parra B, Herrera E, Botero JE, Arce RM, Contreras A, López-Jaramillo P. Periodontal disease severity is related to high levels of C-reactive protein in pre-eclampsia. J Hypertens 2007: 25: 1459-1464.
73. Hill GB. Preterm birth: associations with genital and possibly oral microflora. Ann Periodontol 1998: 3: 222-232.
74. Holbrook WP, Óskarsdóttir Á, Fridjónsson T, Einarsson H, Hauksson A, Geirsson RT. No link between low-grade periodontal disease and preterm birth: a pilot study in a healthy Caucasian population. Acta Odontol Scand 2004: 62: 177-179.
75. Hujoel PP, Lydon-Rochelle M, Robertson PB, del Aquila MA. Cessation of periodontal care during pregnancy: effect on infant birthweight. Eur J Oral Sci 2006: 114: 2-7.
76. Iams JD, Romero R, Culhane JF, Goldenberg RL. Primary, secondary, and tertiary interventions to reduce the morbidity and mortality of preterm birth. Lancet 2008: 371: 164-175.
77. Jadaon J, Shushan A, Ezra Y, Sela HY, Ozcan C, Rojansky N. Behçet's disease and pregnancy. Acta Obstet Gynecol Scand 2005: 84: 939-944.
78. Jamieson DJ, Theiler RN, Rasmussen SA. Emerging infections and pregnancy. Emerg Infect Dis 2006: 12: 1638-1643.
79. Jarjoura K, Devine PC, Perez-Delboy A, Herrera-Abreu M, D'Alton M, Papapanou PN. Markers of periodontal infection and preterm birth. Am J Obstet Gynecol 2005: 192: 513-519.
80. Jeffcoat MK, Geurs NC, Reddy MS, Cliver SP, Goldenberg RL, Hauth JC. Periodontal infection and preterm birth: results of a prospective study. J Am Dent Assoc 2001: 132: 875-880.
81. Jeffcoat MK, Hauth JC, Geurs NC, Reddy MS, Cliver SP, Hodgkins PM, Goldenberg RL. Periodontal disease and preterm birth: results of a pilot intervention study. J Periodontol 2003: 74: 1214-1218.
82. Jensen J, Liljemark W, Bloomquist C. The effect of female sex hormones on subgingival plaque. J Periodontol 1981: 52: 599-602.
83. Jonsson R, Howland BE, Bowden GHW. Relationships between periodontal health, salivary steroids, and Bacteroides intermedius in males, pregnant and non-pregnant women. J Dent Res 1988: 67: 1062-1069.
84. Kaaja RJ, Greer IA. Manifestations of chronic disease during pregnancy. J Am Med Assoc 2005: 294: 2751-2757.
85. Kanda N, Watanabe S. Regulatory roles of sex hormones in cutaneous biology and immunology. J Dermatol Sci 2004: 38: 1-7.
86. Kaplan G, Kiessling R, Teklemariam S, Hancock G, Sheftel G, Job CK, Converse P, Ottenhoff TH, Becx-Bleumink M, Dietz M. The reconstitution of cell-mediated immunity in the cutaneous lesions of lepromatous leprosy by recombinant interleukin-2. J Exp Med 1989: 169: 893-907.
87. Kerr DA. Granuloma pyogenicum. Oral Surg Oral Med Oral Pathol 1951: 4: 158-176.
88. Khader YS, Jibreal M, Al-Omiri M, Amarin Z. Lack of association between periodontal parameters and preeclampsia. J Periodontol 2006: 77: 1681-1687.
89. Klebanoff M, Searle K. The role of inflammation in preterm birth - focus on periodontitis. Br J Obstet Gynaecol 2006: 113(Suppl. 3): 43-45.
90. Kornman KS, Loesche WJ. The subgingival microbial flora during pregnancy. J Periodontal Res 1980: 15: 111-122.
91. Kornman KS, Loesche WJ. Direct interaction between estradiol and progesterone with Bacteroides asaccharolyticus and Bacteroides melaninogenicus. Infect Immun 1982: 35: 256-263.
92. Kornman KS. Age, supragingival plaque, and steroid hormones as ecological determinants of the subgingival plaque. In: Genco RJ, Mergenhagen RJ. Host-parasite interactions in periodontal disease. Washington DC: American Society for Microbiology, 1982: 132-138.
93. Kostadinov S, Pinar H. Amniotic fluid infection syndrome and neonatal mortality caused by Eikenella corrodens. Pediatr Dev Pathol 2005: 8: 489-492.
94. Kunnen A, Blaauw J, van Doormaal JJ, van Pampus MG, van der Schans CP, Aarnoudse JG, van Winkelhoff AJ, Abbas F. Women with a recent history of early-onset pre-eclampsia have a worse periodontal condition. J Clin Periodontol 2007: 34: 202-207.
95. Laine MA. Effect of pregnancy on periodontal and dental health. Acta Odontol Scand 2002: 60: 257-264.
96. Le HT, Jareinpituk S, Kaewkungwal J, Pitiphat W. Increased risk of preterm birth among non-smoking, non-alcohol drinking women with maternal periodontitis. Southeast Asian J Trop Med Public Health 2007: 38: 586-593.
97. León R, Silva N, Ovalle A, Chaparro A, Ahumada A, Gajardo M, Martinez M, Gamonal J. Detection of Porphyromonas gingivalis in the amniotic fluid in pregnant women with a diagnosis of threatened premature labor. J Periodontol 2007: 78: 1249-1255.
98. Levy I, Rolain JM, Lepidi H, Raoult D, Feinmesser M, Lapidoth M, Ben-Amitai D. Is pyogenic granuloma associated with Bartonella infection? J Am Acad Dermatol 2005: 53: 1065-1066.
99. Lieff S, Boggess KA, Murtha AP, Jared H, Madianos PN, Moss K, Beck J, Offenbacher S. The oral conditions and pregnancy study: periodontal status of a cohort of pregnant women. J Periodontol 2004: 75: 116-126.
100. Lin D, Moss K, Beck JD, Hefti A, Offenbacher S. Persistently high levels of periodontal pathogens associated with preterm pregnancy outcome. J Periodontol 2007: 78: 833-841.
101. Löe H, Silness J. Periodontal disease in pregnancy. I. Prevalence and severity. Acta Odontol Scand 1963: 21: 533-551.
102. López NJ, Smith PC, Gutierrez J. Higher risk of preterm birth and low birth weight in women with periodontal disease. J Dent Res 2002: 81: 58-63.
103. López NJ, Smith PC, Gutierrez J. Periodontal therapy may reduce the risk of preterm low birth weight in women with periodontal disease: a randomized controlled trial. J Periodontol 2002: 73: 911-924.
104. López NJ, Da Silva J, Ipinza J, Gutiérrez J. Periodontal therapy reduces the rate of preterm low birth weight in women with pregnancy-associated gingivitis. J Periodontol 2005: 76: 2144-2153.
105. Louro PM, Fiori HH, Filho PL, Steibel J, Fiori RM. Periodontal disease in pregnancy and low birth weight. J Pediatr (Rio J) 2001: 77: 23-28.
106. Lunardelli AN, Peres MA. Is there an association between periodontal disease, prematurity and low birth weight? A population-based study J Clin Periodontol 2005: 32: 938-946.
107. Machtei EE, Mahler D, Sanduri H, Peled M. The effect of menstrual cycle on periodontal health. J Periodontol 2004: 75: 408-412.
108. Machuca G, Khoshfeiz O, Lacalle JR, Machuca C, Bullón P. The influence of general health and socio-cultural variables on the periodontal condition of pregnant women. J Periodontol 1999: 70: 779-785.
109. Macones GA, Parry S, Nelson DB, Strauss JF, Ludmir J, Cohen AW, Stamilio DM, Appleby D, Clothier B, Sammel MD, Jeffcoat M. Treatment of localized periodontal disease in pregnancy does not reduce the occurrence of preterm birth: results from the Periodontal Infections and Prematurity Study (PIPS). Am J Obstet Gynecol 2010: 202: 147.e1-147.e8.
110. Madianos PN, Lieff S, Murtha AP, Boggess KA, Auten RL Jr, Beck JD, Offenbacher S. Maternal periodontitis and prematurity. Part II: maternal infection and fetal exposure. Ann Periodontol 2001: 6: 175-182.
111. Mahmoud F, Abul H, Omu A, Al-Rayes S, Haines D, Whaley K. Pregnancy-associated changes in peripheral blood lymphocyte populations in normal Kuwaiti women. Gynecol Obstet Invest 2001: 52: 232-236.
112. Maier AW, Orban B. Gingivitis in pregnancy. Oral Surg Oral Med Oral Pathol 1949: 2: 334-373.
113. Maltzer MC, Silva J Jr. In vitro defects of phagocyte chemotaxis during pregnancy. J Clin Microbiol 1980: 11: 170-173.
114. Manau C, Echeverria A, Agueda A, Guerrero A, Echeverria JJ. Periodontal disease definition may determine the association between periodontitis and pregnancy outcomes. J Clin Periodontol 2008: 35: 385-397.
115. Marakoglu I, Gursoy UK, Marakoglu K, Cakmak H, Ataoglu T. Periodontitis as a risk factor for preterm low birth weight. Yonsei Med J 2008: 49: 200-203.
116. Marin C, Segura-Egea JJ, Martínez-Sahuquillo Á, Bullón P. Correlation between infant birth weight and mother's periodontal status. J Clin Periodontol 2005: 32: 299-304.
117. Medawar PB. Some immunological and endocrinological problems raised by the evolution of viviparity in vertebrates. Symp Soc Exp Biol 1953: 7: 320-328.
118. Meurman JH, Furuholm J, Kaaja R, Rintamäki H, Tikkanen U. Oral health in women with pregnancy and delivery complications. Clin Oral Invest 2006: 10: 96-101.
119. Michalowicz BS, Hodges JS, DiAngelis AJ, Lupo VR, Novak MJ, Ferguson JE, Buchanan W, Bofill J, Papapanou PN, Mitchell DA, Matseoane S, Tschida PA, for the OPT Study. Treatment of periodontal disease and the risk of preterm birth. N Engl J Med 2006: 355: 1885-1894.
120. Michalowicz BS, Durand R. Maternal periodontal disease and spontaneous preterm birth. Periodontol 2000 2007: 44: 103-112.
121. Michalowicz BS, DiAngelis AJ, Novak MJ, Buchanan W, Papapanou PN, Mitchell DA, Curran AE, Lupo VR, Ferguson JE, Bofill J, Matseoane S, Deinard AS Jr, Rogers TB. Examining the safety of dental treatment in pregnant women. J Am Dent Assoc 2008: 139: 685-695.
122. Miller AM, Sahl WJ, Brown SA, Young SK, Quinlan CM, Patel PR, Benbrook DM, Naylor MF. The role of human papillomavirus in the development of pyogenic granulomas. Int J Dermatol 1997: 36: 673-676.
123. Mills SE, Cooper PH, Fechner RE. Lobular capillary hemangioma: the underlying lesion of pyogenic granuloma. A study of 73 cases from the oral and nasal mucous membranes. Am J Surg Pathol 1980: 4: 470-479.
124. Mitchell-Lewis D, Engebretson SP, Chen J, Lamster IB, Papapanou PN. Periodontal infections and pre-term birth: early findings from a cohort of young minority women in New York. Eur J Oral Sci 2001: 109: 34-39.
125. Miyagi M, Aoyama H, Morishita M, Iwamoto Y. Effects of sex hormones on chemotaxis of human peripheral polymorphonuclear leukocytes and monocytes. J Periodontol 1992: 63: 28-32.
126. 2 by human peripheral monocytes. J Periodontol 1993: 64: 1075-1078.
127. Mokeem SA, Molla GN, Al-Jewair TS. The prevalence and relationship between periodontal disease and pre-term low birth weight infants at King Khalid University Hospital in Riyadh, Saudi Arabia. J Contemp Dent Pract 2004: 5: 40-56.
128. Moliterno LFM, Montiero B, da Silva Figuerdo CM, Fischer RG. Association between periodontitis and low birth weight: a case-control study. J Clin Periodontol 2005: 32: 886-890.
129. Moore S, Ide M, Coward PY, Randhawa M, Borkowska E, Baylis R, Wilson RF. A prospective study to investigate the relationship between periodontal disease and adverse pregnancy outcome. Br Dent J 2004: 197: 251-258.
130. Moore S, Randhawa M, Ide M. A case-control study to investigate an association between adverse pregnancy outcome and periodontal disease. J Clin Periodontol 2005: 32: 1-5.
131. Moreu G, Téllez L, González-Jaranay M. Relationship between maternal periodontal disease and low-birth-weight pre-term infants. J Clin Periodontol 2005: 32: 622-627.
132. Moss KL, Beck JD, Offenbacher S. Clinical risk factors associated with incidence and progression of periodontal conditions in pregnant women. J Clin Periodontol 2005: 32: 492-498.
133. Moss KL, Ruvo AT, Offenbacher S, Beck JD, Mauriello SM, White RP Jr. Third molars and progression of periodontal pathology during pregnancy. J Oral Maxillofac Surg 2007: 65: 1065-1069.
134. Muñoz M, Monje F, del Hoyo JRA, Martín-Granizo R. Oral angiosarcoma misdiagnosed as pyogenic granuloma. J Oral Maxillofac Surg 1998: 56: 488-491.
135. Newnham JP, Newnham IA, Ball CM, Wright M, Pennell CE, Swain J, Doherty DA. Treatment of periodontal disease during pregnancy. A randomized controlled trial. Obstet Gynecol 2009: 114: 1239-1248.
136. Noack B, Klingenberg J, Weigelt J, Hoffmann T. Periodontal status and preterm low birth weight: a case-control study. J Periodontal Res 2005: 40: 339-345.
137. Novak KF, Taylor GW, Dawson DR, Ferguson JE, Novak MJ. Periodontitis and gestational diabetes mellitus: exploring the link in NHANESIII. J Public Health Dent 2006: 66: 163-168.
138. Nugent JL, Baker PN. Periodontal disease and adverse pregnancy outcomes: a systematic review. Br J Obstet Gynaecol 2006: 113: 848-849.
139. Oettinger-Barak O, Barak S, Ohel G, Oettinger M, Kreutzer H, Peled M, Machtei EE. Severe pregnancy complication (preeclampsia) is associated with greater periodontal destruction. J Periodontol 2005: 76: 134-137.
140. Offenbacher S, Katz V, Fertik G, Collins J, Boyd D, Maynor G, McKaig R, Beck J. Periodontal infection as a possible factor for preterm low birth weight. J Periodontol 1996: 67: 1103-1113.
141. Offenbacher S, Lieff S, Boggess KA, Murtha AP, Madianos PN, Champagne CME, McKaig RG, Jared HL, Mauriello SM, Auten RL Jr, Herbert WNP, Beck JD. Maternal periodontitis and prematurity. Part I: obstetric outcome of prematurity and growth restriction. Ann Periodontol 2001: 6: 164-174.
142. Offenbacher S, Riché EL, Barros SP, Bobetsis YA, Lin D, Beck JD. Effects of maternal Campylobacter rectus infection on murine placenta, fetal and neonatal survival, and brain development. J Periodontol 2005: 76: 2133-2143.
143. Offenbacher S, Boggess KA, Murtha AP, Jared HL, Lieff S, McKaig RG, Mauriello SM, Moss KL, Beck JD. Progressive periodontal disease and risk of very preterm delivery. Obstet Gynecol 2006: 107: 29-36.
144. Offenbacher S, Lin D, Strauss R, McKaig R, Irving J, Barros SP, Moss K, Barrow DA, Hefti A, Beck JD. Effects of periodontal therapy during pregnancy on periodontal status, biologic parameters, and pregnancy outcomes: a pilot study. J Periodontol 2006: 77: 2011-2024.
145. Offenbacher S, Beck JD, Jared HL, Mauriello SM, Mendoza LC, Couper DJ, Stewart DD, Murtha AP, Cochran DL, Dudley DJ, Reddy MS, Geurs NC, Hauth JC, for the Maternal Oral Health to Reduce Obstetric Risk (MOTOR) Investigators. Effects of periodontal therapy on rate of preterm delivery. A randomized controlled trial. Obstet Gynecol 2009: 114: 551-559.
146. Østensen M, Villiger PM. The remission of rheumatoid arthritis during pregnancy. Semin Immunopathol 2007: 29: 185-191.
147. Persson GR, Hitti J, Paul K, Hirschi R, Weibel M, Rothen M, Persson RE. Tannerella forsythia and Pseudomonas aeruginosa in subgingival bacterial samples from parous women. J Periodontol 2008: 79: 508-516.
148. Petty HR, Kindzelskii AL, Espinoza J, Romero R. Trophoblast contact deactivates human neutrophils. J Immunol 2006: 176: 3205-3214.
149. Pitiphat W, Gillman MW, Joshipura KJ, Williams PL, Douglass CW, Rich-Edwards JW. Plasma C-reactive protein in early pregnancy and preterm delivery. Am J Epidemiol 2005: 162: 1108-1113.
150. Pitiphat W, Joshipura KJ, Rich-Edwards JW, Williams PL, Douglass CW, Gillman MW. Periodontitis and plasma C-reactive protein during pregnancy. J Periodontol 2006: 77: 821-825.
151. Pitiphat W, Joshipura KJ, Gillman MW, Williams PL, Douglass CW, Rich-Edwards JW. Maternal periodontitis and adverse pregnancy outcomes. Community Dent Oral Epidemiol 2008: 36: 3-11.
152. Polyzos NP, Polyzos IP, Mauri D, Tzioras S, Tsappi M, Cortinovis I, Casazza G. Effect of periodontal disease treatment during pregnancy on preterm birth incidence: a meta-analysis of randomized trials. Am J Obstet Gynecol 2009: 200: 225-232.
153. Poole JA, Claman HN. Immunology of pregnancy. Implications for the mother. Clin Rev Allergy Immunol 2004: 26: 161-170.
154. Poser S, Poser W. Multiple sclerosis and gestation. Neurology 1983: 33: 1422-1427.
155. Powell JL, Bailey CL, Coopland AT, Otis CN, Frank JL, Meyer I. Nd:YAG laser excision of a giant gingival pyogenic granuloma of pregnancy. Lasers Surg Med 1994: 14: 178-183.
156. Pretorius C, Jagatt A, Lamont RF. The relationship between periodontal disease, bacterial vaginosis, and preterm birth. J Perinat Med 2007: 35: 93-99.
157. Progulske-Fox A, Kozarov E, Dorn B, Dunn W Jr, Burks J, Wu Y. Porphyromonas gingivalis virulence factors and invasion of cells of the cardiovascular system. J Periodontal Res 1999: 34: 393-399.
158. Raber-Durlacher JE, Van Steenbergen TJM, Van der Velden U, de Graaff J, Abraham-Inpijn L. Experimental gingivitis during pregnancy and post-partum: clinical, endocrinological, and microbiological aspects. J Clin Periodontol 1994: 21: 549-558.
159. Radnai M, Gorzó I, Nagy E, Urbán E, Novák T, Pál A. A possible association between preterm birth and early periodontitis. Pilot study. J Clin Periodontol 2004: 31: 736-741.
160. Radnai M, Gorzó I, Urbán E, Eller J, Novák T, Pál A. Possible association between mother's periodontal status and preterm delivery. J Clin Periodontol 2006: 33: 791-796.
161. Rajapakse PS, Nagarathne M, Chandrasekra KB, Dasanayake AP. Periodontal disease and prematurity among non-smoking Sri Lankan women. J Dent Res 2005: 84: 274-277.
162. Ramirez JR, Seoane J, Montero J, Gómez GCE, Cerero R. Isolated gingival metastases from hepatocellular carcinoma mimicking a pyogenic granuloma. J Clin Periodontol 2003: 30: 926-929.
163. Redman CW, Sargent IL. Latest advances in understanding preeclampsia. Science 2005: 308: 1592-1595.
164. Riché EL, Boggess KA, Lieff S, Murtha AP, Auten RL, Beck JD, Offenbacher S. Periodontal disease increases the risk of preterm delivery among preeclamptic women. Ann Periodontol 2002: 7: 95-101.
165. Romero BC, Chiquito CS, Elejalde LE, Bernardoni CB. Relationship between periodontal disease in pregnant women and the nutritional condition of their newborns. J Periodontol 2002: 73: 1177-1183.
166. Romero R, Schaudinn C, Kusanovic JP, Gorur A, Gotsch F, Webster P, Nhan-Chang C-L, Erez O, Kim CJ, Espinoza J, Gonçalves LF, Vaisbuch E, Mazaki-Tovi S, Hassan SS, Costerton JW. Detection of a microbial biofilm in intraamniotic infection. Am J Obstet Gynecol 2008: 198: 135.e1-135.e5.
167. Runmarker B, Andersen O. Pregnancy is associated with a lower risk of onset and a better prognosis in multiple sclerosis. Brain 1995: 118: 253-261.
168. Sacks GP, Redman CWG, Sargent IL. Monocytes are primed to produce the Th1 type cytokine IL-12 in normal human pregnancy: an intracellular flow cytometric analysis of peripheral blood mononuclear cells. Clin Exp Immunol 2003: 131: 490-497.
169. Sadatmansouri S, Sedighpoor N, Aghaloo M. Effects of periodontal treatment phaseI on birth term and birth weight. J Indian Soc Pedod Prev Dent 2006: 24: 23-26.
170. Saddki N, Bachok N, Hussain NHN, Zainudin SLA, Sosroseno W. The association between maternal periodontitis and low birth weight infants among Malay women. Community Dent Oral Epidemiol 2008: 36: 296-304.
171. Samant A, Malik CP, Chabra SK, Devi PK. Gingivitis and periodontal disease in pregnancy. J Periodontol 1976: 47: 415-418.
172. Sánchez AR, Bagniewski S, Vallejos N. Correlations between maternal periodontal conditions and preterm birth weight infants. J Int Acad Periodontol 2007: 9: 34-41.
173. Santos-Pereira SA, Giraldo PC, Saba-Chujfi E, Amaral RLG, Morais SS, Fachini AM, Gonçalves AKS. Chronic periodontitis and pre-term labour in Brazilian pregnant women: an association to be analysed. J Clin Periodontol 2007: 34: 208-213.
174. Scannapieco FA, Bush RB, Paju S. Periodontal disease as a risk factor for adverse pregnancy outcomes. A systematic review. Ann Periodontol 2003: 8: 70-78.
175. Schenkein HA, Barbour SE, Berry CR, Kipps B, Tew JG. Invasion of human vascular endothelial cells by Actinobacillus actinomycetemcomitans via the receptor for platelet-activating factor. Infect Immun 2000: 68: 5416-5419.
176. Scheutz F, Baelum V, Matee MI, Mwangosi I. Motherhood and dental disease. Community Dent Health 2002: 19: 67-72.
177. Schumacher A, Wafula PO, Bertoja AZ, Sollwedel A, Thuere C, Wollenberg I, Yagita H, Volk H-D, Zenclussen AC. Mechanisms of action of regulatory Tcells specific for paternal antigens during pregnancy. Obstet Gynecol 2007: 110: 1137-1145.
178. Sembene M, Moreau JC, Mbaye MM, Diallo A, Diallo PD, Ngom M, Benoist HM. Periodontal infection in pregnant women and low birth weight babies. Odontostomatol Trop 2000: 23: 19-22. [Article in French].
179. Sharma R, Maimanuku LR, Morse Z, Pack AR. Preterm low birth weights associated with periodontal disease in the Fiji Islands. Int Dent J 2007: 57: 257-260.
180. Shub A, Swain JR, Newham JP. Periodontal disease and adverse pregnancy outcomes. J Matern Fetal Neonatal Med 2006: 19: 521-528.
181. Shub A, Wong C, Jennings B, Swain JR, Newnham JP. Maternal periodontal disease and perinatal mortality. Aust NZ J Obstet Gynaecol 2009: 49: 130-136.
182. Silness J, Löe H. Periodontal disease in pregnancy. II. Correlation between oral hygiene and periodontal condition. Acta Odontol Scand 1964: 22: 121-135.
183. Silness J, Löe H. Periodontal disease in pregnancy. III. Response to local treatment. Acta Odontol Scand 1964: 24: 747-759.
184. Singh N, Perfect JR. Immune reconstitution syndrome and exacerbation of infections after pregnancy. Clin Infect Dis 2007: 45: 1191-1199.
185. Siqueira FM, Cota LOM, Costa JE, Haddad JPA, Lana AMQ, Costa FO. Intrauterine growth restriction, low birth weight, and preterm birth: adverse pregnancy outcomes and their association with maternal periodontitis. J Periodontol 2007: 78: 2266-2276.
186. Siqueira FM, Cota LOM, Costa JE, Haddad JPA, Lana AMQ, Costa FO. Maternal periodontitis as a potential risk variable for preeclampsia: a case-control study. J Periodontol 2008: 79: 207-215.
187. Skuldbøl T, Johansen KH, Dahlén G, Stoltze K, Holmstrup P. Is pre-term labour associated with periodontitis in a Danish maternity ward? J Clin Periodontol 2006: 33: 177-183.
188. Söderström A, Norkrans G, Lindh M. Hepatitis B virus DNA during pregnancy and post partum: aspects of vertical transmission. J Gastroenterol Hepatol 2003: 35: 814-819.
189. + regulatory T-cell subset. Immunology 2004: 112: 38-43.
190. Song X-Y, Zeng L, Jin W, Pilo CM, Frank ME, Wahl SM. Suppression of streptococcal cell wall-induced arthritis by human chorionic gonadotropin. Arthritis Rheum 2000: 43: 2064-2072.
191. Southwick FS, Purich DL. Intracellular pathogenesis of listeriosis. N Engl J Med 1996: 334: 770-776.
192. Stimson WH. Are pregnancy-associated serum proteins responsible for the inhibition of lymphocyte transformation by pregnancy serum? Clin Exp Immunol 1980: 40: 157-160.
193. Strafford KE, Shellhaas C, Hade EM. Provider and patient perceptions about dental care during pregnancy. J Matern Fetal Neonatal Med 2008: 21: 63-71.
194. Szekeres-Bartho J. Immunological relationship between the mother and the fetus. Int Rev Immunol 2002: 21: 471-495.
195. Taani DQ, Habashneh R, Hammad MM, Batieha A. The periodontal status of pregnant women and its relationship with socio-demographic and clinical variables. J Oral Rehabil 2003: 30: 440-445.
196. Tandon VR, Sharma S, Mahajan A, Khajuria V, Kumar A. Pregnancy and rheumatoid arthritis. Indian J Med Sci 2006: 60: 334-344.
197. Tarannum F, Faizuddin M. Effect of periodontal therapy on pregnancy outcome in women affected by periodontitis. J Periodontol 2007: 78: 2095-2103.
198. Tatakis DN, Trombelli L. Modulation of clinical expression of plaque-induced gingivitis. I. Background review and rationale. J Clin Periodontol 2004: 31: 229-238.
199. Tilakarante A, Soory M, Ranasinghe AW, Corea SMX, Ekanayake SL, De Silva M. Effects of hormonal contraceptives on the periodontium, in a population of rural Sri-Lankan women. J Clin Periodontol 2000: 27: 753-757.
200. Tilakaratne A, Soory M, Ranasinghe AW, Corea SMX, Ekanayake SL, De Silva M. Periodontal disease status during pregnancy and 3months post-partum, in a rural population of Sri-Lankan women. J Clin Periodontol 2000: 27: 787-792.
201. Tjoa ML, van Vugt JM, Go AT, Blankenstein MA, Oudejans CB, van Wijk IL. Elevated C-reactive protein levels during first trimester of pregnancy are indicative of preeclampsia and intrauterine growth restriction. J Reprod Immunol 2003: 59: 29-37.
202. Toida M, Hasegawa T, Watanabe F, Kato K, Makita H, Fujitsuka H, Kato Y, Miyamoto K, Shibata T, Shimokawa K. Lobular capillary hemangioma of the oral mucosa: clinicopathological study of 43 cases with a special reference to immunohistochemical characterization of the vascular elements. Pathol Int 2003: 53: 1-7.
203. Toygar HU, Seydaoglu G, Kurklu S, Guzeldemir E, Arpak N. Periodontal health and adverse pregnancy outcome in 3, 576 Turkish women. J Periodontol 2007: 78: 2081-2094.
204. Tsukimori K, Fukushima K, Komatsu H, Nakano H. Neutrophil function during pregnancy: is nitric acid production correlated with superoxide production? Am J Reprod Immunol 2006: 55: 99-105.
205. Urbán E, Radnai M, Novák T, Gorzó I, Pál A, Nagy E. Distribution of anaerobic bacteria among pregnant periodontitis patients who experience preterm delivery. Anaerobe 2006: 12: 52-57.
206. Vergnes J-N, Sixou M. Preterm low birth weight and maternal periodontal status: a meta-analysis. Am J Obstet Gynecol 2007: 196: 135.e1-135.e7.
207. Vettore MV, Lamarca GA, Leão ATT, Thomaz FB, Sheiham A, Leal MC. Periodontal infection and adverse pregnancy outcomes: a systematic review of epidemiological studies. Cad Saude Publica 2006: 22: 2041-2053 [Article in Portuguese]
208. Vettore MV, Leal MC, Leão AT, da Silva AMM, Lamarca GA, Sheiham A. The relationship between periodontitis and preterm low birthweight. J Dent Res 2008: 87: 73-78.
209. Wang P-H, Chao H-T, Lee W-L, Yuan C-C, Ng H-T. Severe bleeding from a pregnancy tumor. A case report. J Reprod Med 1997: 42: 359-362.
210. Whitaker SB, Bouquot JE, Alimario AE, Whitaker TJ Jr. Identification and semiquantification of estrogen and progesterone receptors in pyogenic granulomas of pregnancy. Oral Surg Oral Med Oral Pathol 1994: 78: 755-760.
211. Wood S, Frydman A, Cox S, Brant R, Needoba S, Eley B, Sauve R. Periodontal disease and spontaneous pre-term birth: a case-control study. BMC Pregnancy Childbirth 2006: 6: 24-30.
212. Xiong X, Buekens P, Fraser WD, Beck J, Offenbacher S. Periodontal disease and adverse pregnancy outcomes: a systematic review. Br J Obstet Gynaecol 2006: 113: 135-143.
213. Xiong X, Buekens P, Vastardis S, Pridjian G. Periodontal disease and gestational diabetes mellitus. Am J Obstet Gynecol 2006: 195: 605-615.
214. Xiong X, Buekens P, Vastardis S, Yu SM. Periodontal disease and pregnancy outcomes: state-of-the-science. Obstet Gynecol Surv 2007: 62: 1086-1089.
215. 2 concentrations and clinical parameters in pregnancy. J Periodontol 2002: 73: 173-177.
216. Yeo A, Smith MA, Lin D, Riché EL, Moore A, Elter J, Offenbacher S. Campylobacter rectus mediates growth restriction in pregnant mice. J Periodontol 2005: 76: 551-557.
217. Yokoyama M, Hinode D, Yoshioka M, Fukui M, Tanabe S, Grenier D, Ito H-O. Relationship between Campylobacter rectus and periodontal status during pregnancy. Oral Microbiol Immunol 2008: 23: 55-59.
218. Yuan K, Jin Y-T, Lin MT. Expression of Tie-2, angiopoietin-1, angiopoietin-2, ephrinB2 and EphB4 in pyogenic granuloma of human gingival implicates their roles in inflammatory angiogenesis. J Periodontal Res 2000: 35: 165-171.
219. Yuan K, Jin Y-T, Lin MT. The detection and comparison of angiogenesis-associated factors in pyogenic granuloma by immunochemistry. J Periodontol 2000: 71: 701-709.
220. Yuan K, Wing L-YC, Lin MT. Pathogenic roles of angiogenic factors in pyogenic granulomas in pregnancy are modulated by female sex hormones. J Periodontol 2002: 73: 701-708.
221. Yuan K, Lin MT. The roles of vascular endothelial growth factor and angiopoietin-2 in the regression of pregnancy pyogenic granuloma. Oral Dis 2004: 10: 179-185.
222. Zadeh-Modarres S, Amooian B, Bayat-Movahed S, Mohamadi M. Periodontal health in mothers of preterm and term infants. Taiwan J Obstet Gynecol 2007: 46: 157-161.
223. Ziskin DE, Nesse GJ. Pregnancy gingivitis: history, classification, etiology. Am J Orthod Oral Surg 1946: 32: 390-432.