Detection of Porphyromonas gingivalis in the amniotic fluid in pregnant women with a diagnosis of threatened premature labor

Journal of Periodontology

Volumn 78, Issue 7, 2007, Pages 1249-1255

  León, Rubén ^a   Silva, Nora ^a   Ovalle, Alfredo ^b   Chaparro, Alejandra ^a   Ahumada, Alexis ^a   Gajardo, Marta ^a   Martinez, Maria ^b   Gamonal, Jorge ^a  

^a UNIVERSITY OF CHILE   (Chile)

^b HOSPITAL SAN BORJA ARRIARÁN   (Chile)

Author keywords

Periodontal diseases; Porphyromonas gingivalis; Pregnant women; Premature labor

Indexed keywords

BACTERIAL DNA;

AMNION FLUID; ARTICLE; FEMALE; GENETICS; GINGIVITIS; HUMAN; ISOLATION AND PURIFICATION; MICROBIOLOGY; PERIODONTAL DISEASE; PERIODONTICS; PERIODONTITIS; PORPHYROMONAS GINGIVALIS; PREGNANCY; PREMATURE LABOR;

AMNIOTIC FLUID; DNA, BACTERIAL; FEMALE; GINGIVAL CREVICULAR FLUID; HUMANS; OBSTETRIC LABOR, PREMATURE; PERIODONTAL DISEASES; PERIODONTAL INDEX; PERIODONTAL POCKET; PORPHYROMONAS GINGIVALIS; PREGNANCY;

EID: 34547486474     PISSN: 00223492     EISSN: None     Source Type: Journal    
DOI: 10.1902/jop.2007.060368     Document Type: Article

References (33)

1. Page RC, Schroeder HE. Current status of the host response in chronic marginal periodontitis. J Periodontol 1981;52:477-491.
2. Ebersole JL, Taubman MA. The protective nature of host responses in periodontal diseases. Periodontol 2000 1994;5:112-141.
3. Socransky SS, Haffajee AD, Cugini MA, Smith C, Kent RL Jr. Microbial complexes in subgingival plaque. J Clin Periodontol 1998;25:134-144.
4. Slots J, Listgarten MA. Bacteroides gingivalis, Bacteroides intermedius and Actinobacillus actinomycetemcomitans in human periodontal diseases. J Clin Periodontol 1988;15:85-93.
5. Socransky SS, Haffajee AD. Dental biofilms: Difficult therapeutic targets. Periodontol 2000 2002;28:12-55.
6. Offenbacher S, Katz V, Fertik G, et al. Periodontal infection as a possible risk factor for preterm low birth weight. J Periodontol 1996;67:1103-1113.
7. Jeffcoat M, Geurs N, Reddy M, Cliver S, Goldenberg R, Hauth J. Periodontal infection and preterm birth: Results of a prospective study. J Am Dent Assoc 2001;132:875-880.
8. Offenbacher S, Lieff S, Boggess K, et al. Maternal periodontitis and prematurity-part I: Obstetric outcome of prematurity and growth restriction. Ann Periodontol 2001;6:164-174.
9. Boggess K, Lieff S, Murtha A, Moss K, Beck J, Offenbacher S. Maternal periodontal disease is associated with an increased risk for preeclampsia. Obstet Gynecol 2003;101:227-231.
10. Contreras A, Herrera J, Soto J, Arce R, Jaramillo A, Botero J. Periodontitis is associated with preeclampsia in pregnant women. J Periodontol 2006;77:182-188.
11. Lopez N, Smith P, Gutierrez J. Periodontal therapy may reduce the risk of preterm low birth weight in women with periodontal disease: A randomized controlled trial. J Periodontol 2002;73:911-924.
12. Offenbacher S, Jared H, O'Reilly P, et al. Potential pathogenic mechanisms of periodontitis associated pregnancy complications. Ann Periodontol 1998;3: 233-250.
13. Arias F, Rodríguez L, Rayne S, Kraus F. Maternal placental vasculopathy and infection: Two distinct subgroups among patients with preterm labor and preterm ruptured membranes. Am J Obstet Gynecol 1993;168:585-591.
14. Dasanayake A, Boyd D, Madianos P, Offenbacher S, Hills E. The association between Porphyromonas gingivalis-specific maternal serum IgG and low birth weight. J Periodontol 2001;72:1491-1497.
15. Goldenberg R, Hauth J, Andrews W. Intrauterine infection and preterm delivery. N Engl J Med 2000;342: 1500-1507.
16. Ashimoto A, Chen C, Bakker I, Slots J. Polymerase chain reaction detection of 8 putative periodontal pathogens in subgingival plaque of gingivitis and advanced periodontitis lesions. Oral Microbiol Immunol 1996;11:266-273.
17. Sambrook J, Russell D. Molecular Cloning: A Laboratory Manual, 3rd ed. Cold Spring Harbor, NY: Cold Spring Harbor Laboratory Press; 2001.
18. Lin D, Smith M, Champagne C, Elter J, Beck J, Offenbacher S. Effects of a Porphyromonas gingivalis infection during pregnancy increases maternal tumor necrosis factor alpha, suppresses maternal interleukin-10, and enhances fetal growth restriction and resorption in mice. Infect Immun 2003;71:5156-5162.
19. Jeffcoat M, Geurs N, Reddy M, Cliver S, Goldenerg R, Hauth J. Periodontal infection and preterm birth: Results of a prospective study. J Am Dent Assoc 2001; 132:875-880.
20. Boggess K, Madianos P, Preisser J, Moise K, Oftenbacher S. Chronic maternal and fetal Porphyromonas gingivalis exposure during pregnancy in rabbits. Am J Obstet Gynecol 2005;192:554-557.
21. Boggess K, Price W, Preisser J, Moise K, Offenbacher S. Insulin-like growth factor and interleukin-1β levels and subsequent fetal size in response to chronic Porphyromonas gingivalis exposure in the pregnant rabbit. Am J Obstet Gynecol 2005;193:1219-1223.
22. Lin D, Smith M, Elter J, et al. Porphyromonas gingivalis infection in pregnant mice is associated with placental dissemination, an increase in the placental Th1/Th2 cytokine ratio, and fetal growth restriction. Infect Immun 2003;71:5163-5168.
23. Madianos P, Lieff S, Murtha A, et al. Maternal periodontitis and prematury - part II: Maternal infection and fetal exposure. Ann Periodontol 2001;6: 175-182.
24. Gemmell E, Winning T, Bird P, Seymour G. Cytokine profiles of lesional and splenic T cells in Porphyromonas gingivalis infection in a murine model. J Periodontol 1998;69:1131-1138.
25. Gemmell E, Grieco D, Cullinan M, Westerman B, Seymour G. The proportion of interleukin-4, interferon-gamma and interleukin-10-positive cells in Porphyromonas gingivalis-specific T-cell lines established from P. gingivalis-positive subjects. Oral Microbiol Immunol 1999;14:267-274.
26. Sacks G, Sargent I, Redman C. An innate view of human pregnancy. Immunol Today 1999;20:114-118.
27. Vizi E, Szelenyi J, Selmeczy Z, Papp Z, Nemeth Z, Hasko G. Enhanced tumor necrosis factor-alpha-specific and decreased interleukin-10-specific immune responses to LPS during the third trimester of pregnancy in mice. J Endocrinol 2001;171:355-361.
28. Nitsos I, Moss T, Cock M, Harding R, Newnham J. Fetal responses to intra-amniotic endotoxin in sheep. J Soc Gynecol Investig 2002;9:80-85.
29. Jobe A, Newnham J, Willet K, et al. Effects of antenatal endotoxin and glucocorticoids on the lungs of preterm lambs. Am J Obstet Gynecol 2000;182:401-408.
30. Newnham J, Shub A, Jobe A, et al. The effects of intra-amniotic injection of periodontopathic lipopolysaccharides in sheep. Am J Obstet Gynecol 2005; 193:313-321.
31. Katz J, Ward D, Michalek S. Effect of host responses on the pathogenicity of strains of Porphyromonas gingivalis. Oral Microbiol Immunol 1996;11:309-318.
32. Hah Y, Redline R, Li M, Yin L, Hill G, McCormick T. Fusobacterium nucleatum induces premature and term stillbirths in pregnant mice: Implication of oral bacteria in preterm birth. Infect Immun 2004;72:2272-2279.
33. Hah Y, Ikegami A, Bissada N, Herbst M, Redline R, Ashmead G. Transmission of an uncultivated Bergeyella strain from oral cavity to amniotic fluid in a case of preterm birth. J Clin Microbiol 2006;44:1475-1483.