Expression of Tie-2, angiopoietin-1, angiopoietin-2, ephrinB2 and EphB4 in pyogenic granuloma of human gingiva implicates their roles in inflammatory angiogenesis

Journal of Periodontal Research

Volumn 35, Issue 3, 2000, Pages 165-171

  Yuan, Kuo ^a   Jin, Ying Tai ^a   Lin, Ming T ^a  

^a NATIONAL CHENG KUNG UNIVERSITY   (Taiwan)

Author keywords

Angiogenesis; Angiopoietin; Eph; Pyogenic granuloma; Tie 2

Indexed keywords

ANGIOPOIETIN 1; ANGIOPOIETIN 2; ANGIOPOIETIN RECEPTOR; ANGPT1 PROTEIN, HUMAN; AUTACOID; EPHRIN B2; MEMBRANE PROTEIN; PROTEIN TYROSINE KINASE;

ADULT; ARTICLE; BIOSYNTHESIS; DRUG ANTAGONISM; ENZYMOLOGY; FEMALE; GINGIVA; GINGIVA DISEASE; HUMAN; IMMUNOHISTOCHEMISTRY; MACROPHAGE; MALE; METABOLISM; MIDDLE AGED; MONOCYTE; NEOVASCULARIZATION (PATHOLOGY); PERIODONTITIS; PROTEIN SYNTHESIS; PYOGENIC GRANULOMA; UPREGULATION; VASCULAR ENDOTHELIUM; VASCULARIZATION;

ADULT; ANGIOPOIETIN-1; ANGIOPOIETIN-2; ENDOTHELIUM, VASCULAR; EPHRIN-B2; FEMALE; GINGIVA; GINGIVAL DISEASES; GRANULOMA, PYOGENIC; HUMANS; IMMUNOHISTOCHEMISTRY; INFLAMMATION MEDIATORS; MACROPHAGES; MALE; MEMBRANE GLYCOPROTEINS; MEMBRANE PROTEINS; MIDDLE AGED; MONOCYTES; NEOVASCULARIZATION, PATHOLOGIC; PERIODONTITIS; PROTEIN BIOSYNTHESIS; RECEPTOR PROTEIN-TYROSINE KINASES; RECEPTOR, TIE-2; UP-REGULATION;

EID: 0034198659     PISSN: 00223484     EISSN: None     Source Type: Journal    
DOI: 10.1034/j.1600-0765.2000.035003165.x     Document Type: Article

References (26)

1. Angeloppulous AP. Pyogenic granuloma of the oral cavity: statistical analysis of its clinical feature. J Oral Surg 1971; 29:840-845.
2. Aley TD, Nartey NO, Wysocki GP. Pregnancy tumor: an analysis. Oral Surg Oral Med Oral Pathol 1991;72: 196-199.
3. Regezi JA, Sciubba JJ. Oral pathology: clinical-pathologic correlations. Philadelphia: WB Saunders, 1989;131-132.
4. Hanahan D. Signaling vascular morphogenesis and maintenance. Science 1997;277:48-50.
5. Wang HU, Chen Z-F, Anderson DJ. Molecular distinction and angiogenic interaction between embryonic arteries and veins revealed by ephrin-B2 and its receptor Eph-B4. Cell 1998;93:741-753.
6. Sato TN, Tozawa Y, Deutsch U et al. Distinct roles of the receptor tyrosine kinases Tie-1 and Tie-2 in blood vessel formation. Nature 1995;376:70-74.
7. Vikkula M, Boon LM, Carraway KL et al. Vascular dysmorphogenesis caused by an activating mutation in the receptor tyrosine kinase TIE2. Cell 1996;87:1181-1190.
8. Suri C, Jones PF, Patan S et al. Requisite role of angiopoietin-1, a ligand for the Tie-2 receptor, during embryonic angiogenesis. Cell 1996;87:1171-1180.
9. Maisonpierre PC, Suri C, Jones PF et al. Angiopoietin-2, a natural antagonist for Tie2 that disrupts in vivo angiogenesis. Science 1997;277:55-60.
10. Stratmann A, Risau W, Plate KH. Cell type-specific expression of angiopoietin-1 and angiopoietin-2 suggests a role in glioblastoma angiogenesis. Am J Pathol 1998; 153:1459-1466.
11. Witzenbichler B, Maisonpierre PC, Jones P et al. Chemotactic properties of angiopoietin-1 and -2, ligands for the endothelial-specific receptor tyrosine kinase Tie2. J Biol Chem 1998;273:18514-18521.
12. Goede V, Schmidt T, Kimmina S et al. Analysis of blood vessel maturation processes during cyclic ovarian angiogenesis. Lab Invest 1998;78:1385-1394.
13. Asahara T, Chen D, Takahashi T et al. Tie2 receptor ligands, angiopoietin-1 and angiopoietin-2, modulate VEGF-induced postnatal neovascularization. Circ Res 1998;83:233-240.
14. Drescher U. The Eph family in the patterning of neural development. Curr Biol 1997;7:R799-R807.
15. Bruckner K, Klein R. Signaling by Eph receptors and their ephrin ligands. Curr Opin Neurobiol 1998;8:375-382.
16. Page RC, Schroeder HE. Pathogenesis of inflammatory periodontal diseases. A summary of current work. Lab Invest 1976;33:235-249.
17. Caffesse RG, Nasjleti CE, Kowalski CJ. Carrageenan-induced inflammation and its effects on mitotic activity and keratinization of gingival epithelium. A histologic and autoradiographic study. J Periodontol 1985;56:132-138.
18. Goede V, Schmidt T, Kimmina S et al. Analysis of blood vessel maturation processes during cyclic ovarian angiogenesis. Lab Invest 1998;78:1385-1394.
19. Nikolova Z. Djonov V, Zuercher G et al. Cell-type specific and estrogen dependent expression of the receptor tyrosine kinase EphB4 and its ligand ephrin-B2 during mammary gland morphogenesis. J Cell Sci 1998;111:2741-2751.
20. Korpelainen EI, Alitalo K. Signaling angiogenesis and lymphangiogenesis. Curr Opin Cell Biol 1998;10:159-164.
21. Korhonen J, Polvi A, Partanen J et al. The mouse tie receptor tyrosine kinase gene: expression during embryonic angiogenesis. Oncogene 1994;9:395-403.
22. Dumont DJ, Fong G-H, Puri MC et al. Vascularization of the mouse embryo: a study of flk-1, tek, tie and VEGF expression during development. Dev Dynam 1995; 203:80-92.
23. Dumont DJ, Gradwohl G, Fong G-H et al. Dominant-negative and targeted null mutations in the endothelial-specific receptor tyrosine kinase, tek, reveal a critical role in vasculogenesis of the embryo. Gene Dev 1994;8:1897-1909.
24. Lauren J, Gunji Y, Alitalo K. Is angiopoietin-2 necessary for the initiation of tumor angiogenesis? Am J Pathol 1998;153:1333-1339.
25. Adams RH, Wilkinson GA, Weiss C et al. Roles of ephrinB ligands and EphB receptors in cardiovascular development: demarcation of arterial/venous domains, vascular morphogenesis, and sprouting angiogenesis. Gene Dev 1999;13:295-306.
26. Phillips GD, Whitehead RA, Knighton DR. Initiation and pattern of angiogenesis in wound healing in the rat. Am J Anat 1991;192:257-262.