메뉴 건너뛰기




Volumn 54, Issue 1, 2013, Pages 44-54

CCN1 expression in hepatocytes contributes to macrophage infiltration in nonalcoholic fatty liver disease in mice

Author keywords

Cell signaling; Chemotaxis; Cyr61; Cytokines; Diet and dietary lipids; Fatty acid; Nonalcoholic steatohepatitis

Indexed keywords

ALANINE AMINOTRANSFERASE; ALPHA INTEGRIN; ALPHA M INTEGRIN; ASPARTATE AMINOTRANSFERASE; CYSTEINE RICH PROTEIN 61; FATTY ACID; LIPOPOLYSACCHARIDE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE KINASE 2; MYELOID DIFFERENTIATION FACTOR 88; TOLL LIKE RECEPTOR 4; TRANSCRIPTION FACTOR AP 1; UNCLASSIFIED DRUG;

EID: 84871242322     PISSN: 00222275     EISSN: 15397262     Source Type: Journal    
DOI: 10.1194/jlr.M026013     Document Type: Article
Times cited : (56)

References (32)
  • 1
    • 79959517565 scopus 로고    scopus 로고
    • Human fatty liver disease: Old questions and new insights
    • Cohen, J. C., J. D. Horton, and H. H. Hobbs. 2011. Human fatty liver disease: old questions and new insights. Science. 332: 1519-1523.
    • (2011) Science , vol.332 , pp. 1519-1523
    • Cohen, J.C.1    Horton, J.D.2    Hobbs, H.H.3
  • 2
    • 33644547706 scopus 로고    scopus 로고
    • Nonalcoholic fatty liver disease: From steatosis to cirrhosis
    • Farrell, G. C., and C. Z. Larter. 2006. Nonalcoholic fatty liver disease: from steatosis to cirrhosis. Hepatology. 43: S99-S112.
    • (2006) Hepatology , vol.43
    • Farrell, G.C.1    Larter, C.Z.2
  • 4
    • 1942454793 scopus 로고    scopus 로고
    • Nonalcoholic Steatohepatitis
    • DOI 10.1055/s-2004-823098
    • Brunt, E. M. 2004. Nonalcoholic steatohepatitis. Semin. Liver Dis. 24: 3-20. (Pubitemid 38496045)
    • (2004) Seminars in Liver Disease , vol.24 , Issue.1 , pp. 3-20
    • Brunt, E.M.1
  • 5
    • 78049522194 scopus 로고    scopus 로고
    • Evolution of inflammation in nonalcoholic fatty liver disease: The multiple parallel hits hypothesis
    • Tilg, H., and A. R. Moschen. 2010. Evolution of inflammation in nonalcoholic fatty liver disease: the multiple parallel hits hypothesis. Hepatology. 52: 1836-1846.
    • (2010) Hepatology , vol.52 , pp. 1836-1846
    • Tilg, H.1    Moschen, A.R.2
  • 6
    • 59649107705 scopus 로고    scopus 로고
    • Functions and mechanisms of action of CCN matricellular proteins
    • Chen, C. C., and L. F. Lau. 2009. Functions and mechanisms of action of CCN matricellular proteins. Int. J. Biochem. Cell Biol. 41: 771-783.
    • (2009) Int. J. Biochem. Cell Biol. , vol.41 , pp. 771-783
    • Chen, C.C.1    Lau, L.F.2
  • 7
    • 0347915577 scopus 로고    scopus 로고
    • CCN proteins: Multifunctional signalling regulators
    • DOI 10.1016/S0140-6736(03)15172-0
    • Perbal, B. 2004. CCN proteins: multifunctional signalling regulators. Lancet. 363: 62-64. (Pubitemid 38076928)
    • (2004) Lancet , vol.363 , Issue.9402 , pp. 62-64
    • Perbal, B.1
  • 8
    • 77951921964 scopus 로고    scopus 로고
    • Matricellular protein CCN1 activates a proinflammatory genetic program in murine macrophages
    • Bai, T., C. C. Chen, and L. F. Lau. 2010. Matricellular protein CCN1 activates a proinflammatory genetic program in murine macrophages. J. Immunol. 184: 3223-3232.
    • (2010) J. Immunol. , vol.184 , pp. 3223-3232
    • Bai, T.1    Chen, C.C.2    Lau, L.F.3
  • 9
    • 35948937180 scopus 로고    scopus 로고
    • Cyr61/CCN1 is a tumor suppressor in human hepatocellular carcinoma and involved in DNA damage response
    • DOI 10.1016/j.biocel.2007.06.020, PII S1357272507002191
    • Feng, P., B. Wang, and E. C. Ren. 2008. Cyr61/CCN1 is a tumor suppressor in human hepatocellular carcinoma and involved in DNA damage response. Int. J. Biochem. Cell Biol. 40: 98-109. (Pubitemid 350064578)
    • (2008) International Journal of Biochemistry and Cell Biology , vol.40 , Issue.1 , pp. 98-109
    • Feng, P.1    Wang, B.2    Ren, E.C.3
  • 10
    • 33947126121 scopus 로고    scopus 로고
    • Cytotoxicity of TNFalpha is regulated by integrin-mediated matrix signaling
    • DOI 10.1038/sj.emboj.7601596, PII 7601596
    • Chen, C. C., J. L. Young, R. I. Monzon, N. Chen, V. Todorovic, and L. F. Lau. 2007. Cytotoxicity of TNFalpha is regulated by integrin-mediated matrix signaling. EMBO J. 26: 1257-1267. (Pubitemid 46398716)
    • (2007) EMBO Journal , vol.26 , Issue.5 , pp. 1257-1267
    • Chen, C.-C.1    Young, J.L.2    Monzon, R.I.3    Chen, N.4    Todorovic, V.5    Lau, L.F.6
  • 11
    • 0031005034 scopus 로고    scopus 로고
    • The human growth factor-inducible immediate early gene, CYR61, maps to chromosome 1p
    • Jay, P., J. L. Berge-Lefranc, C. Marsollier, C. Mejean, S. Taviaux, and P. Berta. 1997. The human growth factor-inducible immediate early gene, CYR61, maps to chromosome 1p. Oncogene. 14: 1753-1757. (Pubitemid 27198948)
    • (1997) Oncogene , vol.14 , Issue.14 , pp. 1753-1757
    • Jay, P.1    Berge-Lefranc, J.L.2    Marsollier, C.3    Mejean, C.4    Taviaux, S.5    Berta, P.6
  • 14
    • 78149251115 scopus 로고    scopus 로고
    • Modulation of hepatic cytochrome P450s by Citrobacter rodentium infection in interleukin-6- And interferon-{gamma}-null mice
    • Nyagode, B. A., C. M. Lee, and E. T. Morgan. 2010. Modulation of hepatic cytochrome P450s by Citrobacter rodentium infection in interleukin-6- and interferon-{gamma}-null mice. J. Pharmacol. Exp. Ther. 335: 480-488.
    • (2010) J. Pharmacol. Exp. Ther. , vol.335 , pp. 480-488
    • Nyagode, B.A.1    Lee, C.M.2    Morgan, E.T.3
  • 15
    • 36849030710 scopus 로고    scopus 로고
    • Methods of in vitro macrophage maturation confer variable inflammatory responses in association with altered expression of cell surface dectin-1
    • DOI 10.1016/j.jim.2007.10.003, PII S0022175907003225
    • Gersuk, G. M., L. W. Razai, and K. A. Marr. 2008. Methods of in vitro macrophage maturation confer variable inflammatory responses in association with altered expression of cell surface dectin-1. J. Immunol. Methods. 329: 157-166. (Pubitemid 350235469)
    • (2008) Journal of Immunological Methods , vol.329 , Issue.1-2 , pp. 157-166
    • Gersuk, G.M.1    Razai, L.W.2    Marr, K.A.3
  • 16
    • 53249101515 scopus 로고    scopus 로고
    • Probiotics improve high fat diet-induced hepatic steatosis and insulin resistance by increasing hepatic NKT cells
    • Ma, X., J. Hua, and Z. Li. 2008. Probiotics improve high fat diet-induced hepatic steatosis and insulin resistance by increasing hepatic NKT cells. J. Hepatol. 49: 821-830.
    • (2008) J. Hepatol. , vol.49 , pp. 821-830
    • Ma, X.1    Hua, J.2    Li, Z.3
  • 17
    • 79953225865 scopus 로고    scopus 로고
    • Alterations in marginal zone macrophages and marginal zone B cells in old mice
    • Birjandi, S. Z., J. A. Ippolito, A. K. Ramadorai, and P. L. Witte. 2011. Alterations in marginal zone macrophages and marginal zone B cells in old mice. J. Immunol. 186: 3441-3451.
    • (2011) J. Immunol. , vol.186 , pp. 3441-3451
    • Birjandi, S.Z.1    Ippolito, J.A.2    Ramadorai, A.K.3    Witte, P.L.4
  • 18
    • 25844437136 scopus 로고    scopus 로고
    • Dietary factors alter hepatic innate immune system in mice with nonalcoholic fatty liver disease
    • DOI 10.1002/hep.20826
    • Li, Z., M. J. Soloski, and A. M. Diehl. 2005. Dietary factors alter hepatic innate immune system in mice with nonalcoholic fatty liver disease. Hepatology. 42: 880-885. (Pubitemid 41401126)
    • (2005) Hepatology , vol.42 , Issue.4 , pp. 880-885
    • Li, Z.1    Soloski, M.J.2    Diehl, A.M.3
  • 19
    • 36349010120 scopus 로고    scopus 로고
    • A high-fat diet and regulatory T cells influence susceptibility to endotoxin-induced liver injury
    • DOI 10.1002/hep.21823
    • Ma, X., J. Hua, A. R. Mohamood, A. R. Hamad, R. Ravi, and Z. Li. 2007. A high-fat diet and regulatory T cells influence susceptibility to endotoxin-induced liver injury. Hepatology. 46: 1519-1529. (Pubitemid 350155534)
    • (2007) Hepatology , vol.46 , Issue.5 , pp. 1519-1529
    • Ma, X.1    Hua, J.2    Mohamood, A.R.3    Hamad, A.R.A.4    Ravi, R.5    Li, Z.6
  • 20
    • 0348134733 scopus 로고    scopus 로고
    • Diet associated hepatic steatosis sensitizes to Fas mediated liver injury in mice
    • DOI 10.1016/S0168-8278(03)00460-4
    • Feldstein, A. E., A. Canbay, M. E. Guicciardi, H. Higuchi, S. F. Bronk, and G. J. Gores. 2003. Diet associated hepatic steatosis sensitizes to Fas-mediated liver injury in mice. J. Hepatol. 39: 978-983. (Pubitemid 37523769)
    • (2003) Journal of Hepatology , vol.39 , Issue.6 , pp. 978-983
    • Feldstein, A.E.1    Canbay, A.2    Guicciardi, M.E.3    Higuchi, H.4    Bronk, S.F.5    Gores, G.J.6
  • 21
    • 0037097845 scopus 로고    scopus 로고
    • 2 as an adhesion receptor on peripheral blood monocytes for Cyr61 (CCN1) and connective tissue growth factor (CCN2): Immediate-early gene products expressed in atherosclerotic lesions
    • DOI 10.1182/blood.V99.12.4457
    • Schober, J. M., N. Chen, T. M. Grzeszkiewicz, I. Jovanovic, E. E. Emeson, T. P. Ugarova, R. D. Ye, L. F. Lau, and S. C. Lam. 2002. Identification of integrin alpha(M)beta(2) as an adhesion receptor on peripheral blood monocytes for Cyr61 (CCN1) and connective tissue growth factor (CCN2): immediate-early gene products expressed in atherosclerotic lesions. Blood. 99: 4457-4465. (Pubitemid 34627215)
    • (2002) Blood , vol.99 , Issue.12 , pp. 4457-4465
    • Schober, J.M.1    Chen, N.2    Grzeszkiewicz, T.M.3    Jovanovic, I.4    Emeson, E.E.5    Ugarova, T.P.6    Ye, R.D.7    Lau, L.F.8    Lam, S.C.-T.9
  • 22
    • 67649231054 scopus 로고    scopus 로고
    • Fas-mediated apoptosis is regulated by the extracellular matrix protein CCN1 (CYR61) in vitro and in vivo
    • Juric, V., C. C. Chen, and L. F. Lau. 2009. Fas-mediated apoptosis is regulated by the extracellular matrix protein CCN1 (CYR61) in vitro and in vivo. Mol. Cell. Biol. 29: 3266-3279.
    • (2009) Mol. Cell. Biol. , vol.29 , pp. 3266-3279
    • Juric, V.1    Chen, C.C.2    Lau, L.F.3
  • 23
    • 49649094683 scopus 로고    scopus 로고
    • Beyond insulin resistance: Innate immunity in nonalcoholic steatohepatitis
    • Maher, J. J., P. Leon, and J. C. Ryan. 2008. Beyond insulin resistance: innate immunity in nonalcoholic steatohepatitis. Hepatology. 48: 670-678.
    • (2008) Hepatology , vol.48 , pp. 670-678
    • Maher, J.J.1    Leon, P.2    Ryan, J.C.3
  • 25
    • 67349205002 scopus 로고    scopus 로고
    • Kupffer cells in non-alcoholic fatty liver disease: The emerging view
    • Baffy, G. 2009. Kupffer cells in non-alcoholic fatty liver disease: the emerging view. J. Hepatol. 51: 212-223.
    • (2009) J. Hepatol. , vol.51 , pp. 212-223
    • Baffy, G.1
  • 27
    • 67349139869 scopus 로고    scopus 로고
    • Lipopolysaccharide triggered TNF-alpha-induced hepatocyte apoptosis in a murine non-alcoholic steatohepatitis model
    • Kudo, H., T. Takahara, Y. Yata, K. Kawai, W. Zhang, and T. Sugiyama. 2009. Lipopolysaccharide triggered TNF-alpha-induced hepatocyte apoptosis in a murine non-alcoholic steatohepatitis model. J. Hepatol. 51: 168-175.
    • (2009) J. Hepatol. , vol.51 , pp. 168-175
    • Kudo, H.1    Takahara, T.2    Yata, Y.3    Kawai, K.4    Zhang, W.5    Sugiyama, T.6
  • 28
    • 77951918926 scopus 로고    scopus 로고
    • Macrophages, inflammation, and insulin resistance
    • Olefsky, J. M., and C. K. Glass. 2010. Macrophages, inflammation, and insulin resistance. Annu. Rev. Physiol. 72: 219-246.
    • (2010) Annu. Rev. Physiol. , vol.72 , pp. 219-246
    • Olefsky, J.M.1    Glass, C.K.2
  • 29
    • 56649083495 scopus 로고    scopus 로고
    • Mechanisms of disease progression in nonalcoholic fatty liver disease
    • Jou, J., S. S. Choi, and A. M. Diehl. 2008. Mechanisms of disease progression in nonalcoholic fatty liver disease. Semin. Liver Dis. 28: 370-379.
    • (2008) Semin. Liver Dis. , vol.28 , pp. 370-379
    • Jou, J.1    Choi, S.S.2    Diehl, A.M.3
  • 30
    • 3042824524 scopus 로고    scopus 로고
    • Free fatty acids promote hepatic lipotoxicity by stimulating TNF-alpha expression via a lysosomal pathway
    • DOI 10.1002/hep.20283
    • Feldstein, A. E., N. W. Werneburg, A. Canbay, M. E. Guicciardi, S. F. Bronk, R. Rydzewski, L. J. Burgart, and G. J. Gores. 2004. Free fatty acids promote hepatic lipotoxicity by stimulating TNF-alpha expression via a lysosomal pathway. Hepatology. 40: 185-194. (Pubitemid 38868937)
    • (2004) Hepatology , vol.40 , Issue.1 , pp. 185-194
    • Feldstein, A.E.1    Werneburg, N.W.2    Canbay, A.3    Guicciardi, M.E.4    Bronk, S.F.5    Rydzewski, R.6    Burgart, L.J.7    Gores, G.J.8
  • 31
    • 34548746833 scopus 로고    scopus 로고
    • Palmitic acid induces production of proinflammatory cytokine interleukin-8 from hepatocytes
    • DOI 10.1002/hep.21752
    • Joshi-Barve, S., S. S. Barve, K. Amancherla, L. Gobejishvili, D. Hill, M. Cave, P. Hote, and C. J. McClain. 2007. Palmitic acid induces production of proinflammatory cytokine interleukin-8 from hepatocytes. Hepatology. 46: 823-830. (Pubitemid 47436129)
    • (2007) Hepatology , vol.46 , Issue.3 , pp. 823-830
    • Joshi-Barve, S.1    Barve, S.S.2    Amancherla, K.3    Gobejishvili, L.4    Hill, D.5    Cave, M.6    Hote, P.7    McClain, C.J.8
  • 32
    • 79959573042 scopus 로고    scopus 로고
    • Fatty acid and endotoxin activate inflammasomes in mouse hepatocytes that release danger signals to stimulate immune cells
    • Csak, T., M. Ganz, J. Pespisa, K. Kodys, A. Dolganiuc, and G. Szabo. 2011. Fatty acid and endotoxin activate inflammasomes in mouse hepatocytes that release danger signals to stimulate immune cells. Hepatology. 54: 133-144.
    • (2011) Hepatology , vol.54 , pp. 133-144
    • Csak, T.1    Ganz, M.2    Pespisa, J.3    Kodys, K.4    Dolganiuc, A.5    Szabo, G.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.